| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arwen L Hunter, Jingchun Zhang, Shirley C Chen, Xiaoning Si, Brian Wong, Daryoush Ekhterae, Honglin Luo, David J Granvill. Apoptosis repressor with caspase recruitment domain (ARC) inhibits myogenic differentiation. FEBS letters. vol 581. issue 5. 2007-04-17. PMID:17292893. |
apoptosis repressor with caspase recruitment domain (arc) inhibits myogenic differentiation. |
2007-04-17 |
2023-08-12 |
Not clear |
| Arwen L Hunter, Jingchun Zhang, Shirley C Chen, Xiaoning Si, Brian Wong, Daryoush Ekhterae, Honglin Luo, David J Granvill. Apoptosis repressor with caspase recruitment domain (ARC) inhibits myogenic differentiation. FEBS letters. vol 581. issue 5. 2007-04-17. PMID:17292893. |
apoptosis repressor with caspase recruitment domain (arc), an anti-apoptotic protein, is highly expressed in differentiated heart and skeletal muscle. |
2007-04-17 |
2023-08-12 |
Not clear |
| Arwen L Hunter, Jingchun Zhang, Shirley C Chen, Xiaoning Si, Brian Wong, Daryoush Ekhterae, Honglin Luo, David J Granvill. Apoptosis repressor with caspase recruitment domain (ARC) inhibits myogenic differentiation. FEBS letters. vol 581. issue 5. 2007-04-17. PMID:17292893. |
apoptosis and differentiation share numerous common pathways; therefore, we examined the impact of arc on h9c2-myoblast differentiation. |
2007-04-17 |
2023-08-12 |
Not clear |
| James M Antonini, Stephen S Leonard, Jenny R Roberts, Claudia Solano-Lopez, Shih-Houng Young, Xianglin Shi, Michael D Taylo. Effect of stainless steel manual metal arc welding fume on free radical production, DNA damage, and apoptosis induction. Molecular and cellular biochemistry. vol 279. issue 1-2. 2007-03-01. PMID:16283511. |
effect of stainless steel manual metal arc welding fume on free radical production, dna damage, and apoptosis induction. |
2007-03-01 |
2023-08-12 |
Not clear |
| Yi-Qiang Zhang, Brian Herma. ARC protects rat cardiomyocytes against oxidative stress through inhibition of caspase-2 mediated mitochondrial pathway. Journal of cellular biochemistry. vol 99. issue 2. 2006-11-08. PMID:16639714. |
apoptosis repressor with a card domain (arc) has been demonstrated to protect heart cells against ischemia/reperfusion (i/r) injury. |
2006-11-08 |
2023-08-12 |
rat |
| Yi-Qiang Zhang, Brian Herma. ARC protects rat cardiomyocytes against oxidative stress through inhibition of caspase-2 mediated mitochondrial pathway. Journal of cellular biochemistry. vol 99. issue 2. 2006-11-08. PMID:16639714. |
we monitored the extent of apoptosis and activity of multiple components of the intrinsic apoptotic pathway in rat cardiac myoblast cell line h9c2 with either reduced or increased expression of arc during oxidative stress. |
2006-11-08 |
2023-08-12 |
rat |
| Yi-Qiang Zhang, Brian Herma. ARC protects rat cardiomyocytes against oxidative stress through inhibition of caspase-2 mediated mitochondrial pathway. Journal of cellular biochemistry. vol 99. issue 2. 2006-11-08. PMID:16639714. |
these results indicate that arc plays an important role in protection of h9c2 cells against oxidative stress-induced apoptosis by phosphorylation-dependent suppression of the mitochondria-mediated intrinsic pathway, partially initiated through the activation of caspase-2. |
2006-11-08 |
2023-08-12 |
rat |
| Mutsumi Matsuu-Matsuyama, Kazuko Shichijo, Kumio Okaichi, Kouji Ishii, Chung Yang Wen, Eiichiro Fukuda, Toshiyuki Nakayama, Masahiro Nakashima, Yutaka Okumura, Ichiro Sekin. Sucralfate protects intestinal epithelial cells from radiation-induced apoptosis in rats. Journal of radiation research. vol 47. issue 1. 2006-06-01. PMID:16571913. |
the protective effects of sucralfate against arc may be partially due to the suppression of radiation-induced apoptosis by way of p53 in the colon and the protection of the colonic epithelial stem cell region. |
2006-06-01 |
2023-08-12 |
rat |
| Senthil K Radhakrishnan, Andrei L Garte. A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity. Cancer research. vol 66. issue 6. 2006-05-03. PMID:16540679. |
remarkably, arc induced potent apoptosis in human tumor and transformed, but not in normal cells, and possessed strong antiangiogenic activity in vitro. |
2006-05-03 |
2023-08-12 |
human |
| Senthil K Radhakrishnan, Andrei L Garte. A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity. Cancer research. vol 66. issue 6. 2006-05-03. PMID:16540679. |
although arc promoted the accumulation of p53, arc-induced apoptosis in tumor cells was p53-independent, suggesting that it may be useful for the treatment of tumors with functionally inactive p53. |
2006-05-03 |
2023-08-12 |
human |
| Stefan Donath, Peifeng Li, Christian Willenbockel, Nidal Al-Saadi, Volkmar Gross, Thomas Willnow, Michael Bader, Ulrich Martin, Johann Bauersachs, Kai C Wollert, Rainer Dietz, Rüdiger von Harsdor. Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress. Circulation. vol 113. issue 9. 2006-04-07. PMID:16505176. |
the apoptosis repressor with caspase recruitment domain (arc) is a recently discovered antiapoptotic factor with a highly specific expression pattern in striated muscle and neurons. |
2006-04-07 |
2023-08-12 |
Not clear |
| I Mercier, M Vuolo, R Madan, X Xue, A J Levalley, A W Ashton, J-F Jasmin, M T Czaja, E Y Lin, R C Armstrong, J W Pollard, R N Kitsi. ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance. Cell death and differentiation. vol 12. issue 6. 2005-10-06. PMID:15861191. |
arc, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance. |
2005-10-06 |
2023-08-12 |
human |
| Parco M Siu, Randall W Bryner, Zsolt Murlasits, Stephen E Alwa. Response of XIAP, ARC, and FLIP apoptotic suppressors to 8 wk of treadmill running in rat heart and skeletal muscle. Journal of applied physiology (Bethesda, Md. : 1985). vol 99. issue 1. 2005-09-19. PMID:15774698. |
because the antiapoptotic effect of exercise training in postmitotic myocytes could be possibly mediated by the upregulation of apoptotic suppressors, this study examined the effect of endurance training on endogenous apoptotic suppressors including x-chromosome-linked inhibitor of apoptosis protein (xiap), apoptosis repressor with caspases recruitment domain protein (arc), and fadd-like inhibitor protein (flip) in skeletal and cardiac muscles. |
2005-09-19 |
2023-08-12 |
rat |
| R Sasson, E Rimon, A Dantes, T Cohen, V Shinder, A Land-Bracha, A Amsterda. Gonadotrophin-induced gene regulation in human granulosa cells obtained from IVF patients. Modulation of steroidogenic genes, cytoskeletal genes and genes coding for apoptotic signalling and protein kinases. Molecular human reproduction. vol 10. issue 5. 2005-09-16. PMID:15026540. |
novel genes involved in the regulation of apoptosis were found for the first time to be up-regulated by gonadotrophin stimulation, including: bax inhibitor-1, granulysin and apoptosis repressor with caspase recruitment domain (arc). |
2005-09-16 |
2023-08-12 |
human |
| Kazuhiko Yamane, Timothy J Kinsell. CK2 inhibits apoptosis and changes its cellular localization following ionizing radiation. Cancer research. vol 65. issue 10. 2005-07-07. PMID:15899828. |
treatment with a pan-caspase inhibitor or transfection of arc (apoptosis repressor with caspase recruitment domain) suppresses the apoptotic response to ir in the ck2-reduced cells, indicating involvement of caspases. |
2005-07-07 |
2023-08-12 |
human |
| Mi Wang, Suparna Qanungo, Michael T Crow, Michiko Watanabe, Anna-Liisa Niemine. Apoptosis repressor with caspase recruitment domain (ARC) is expressed in cancer cells and localizes to nuclei. FEBS letters. vol 579. issue 11. 2005-05-31. PMID:15848180. |
apoptosis repressor with caspase recruitment domain (arc) is expressed in cancer cells and localizes to nuclei. |
2005-05-31 |
2023-08-12 |
human |
| Rachel A Hill, Sueli Pompolo, Margaret E E Jones, Evan R Simpson, Wah Chin Boo. Estrogen deficiency leads to apoptosis in dopaminergic neurons in the medial preoptic area and arcuate nucleus of male mice. Molecular and cellular neurosciences. vol 27. issue 4. 2005-03-02. PMID:15555924. |
immunohistochemical studies on active caspase-3 and tyrosine hydroxylase (th) revealed apoptosis of dopaminergic neurons in the medial preoptic area (mpo) and arcuate nucleus (arc) of the hypothalamus of 1-year-old (1yo) male arko mice while no active caspase-3 was detected in wild type (wt). |
2005-03-02 |
2023-08-12 |
mouse |
| Dong-Gyu Jo, Joon-Il Jun, Jae-Woong Chang, Yeon-Mi Hong, Sungmin Song, Dong-Hyung Cho, Sang Mi Shim, Ho-June Lee, Chunghee Cho, Do Han Kim, Yong-Keun Jun. Calcium binding of ARC mediates regulation of caspase 8 and cell death. Molecular and cellular biology. vol 24. issue 22. 2004-12-06. PMID:15509781. |
apoptosis repressor with card (arc) possesses the ability not only to block activation of caspase 8 but to modulate caspase-independent mitochondrial events associated with cell death. |
2004-12-06 |
2023-08-12 |
Not clear |
| Young-Jae Nam, Kartik Mani, Anthony W Ashton, Chang-Fu Peng, Barath Krishnamurthy, Yukihiro Hayakawa, Peiyee Lee, Stanley J Korsmeyer, Richard N Kitsi. Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions. Molecular cell. vol 15. issue 6. 2004-10-29. PMID:15383280. |
knockdown of endogenous arc facilitates disc assembly and triggers spontaneous bax activation and apoptosis. |
2004-10-29 |
2023-08-12 |
Not clear |
| Amie J Dirks, Christiaan Leeuwenburg. Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12. Free radical biology & medicine. vol 36. issue 1. 2004-09-23. PMID:14732288. |
the apoptotic inhibitor apoptosis repressor with a caspase recruitment domain (arc), which inhibits cytochrome c release, underwent an age-associated decline in the cytosol but increased with calorie restriction. |
2004-09-23 |
2023-08-12 |
rat |