| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Lan Zhu, Wen-Lin Xu, Xu-Jing Lü, Wen-Juan Luo, Lei-Lei Zhou, Qiao-Yun Che. [Mechanisms of preventive effect of tetrandrine on acquired multidrug resistance in K562 cells]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 2. 2012-01-12. PMID:21518489. |
ttd can also inhibit the expression of survivin and increase the apoptosis of cells induced by adm. |
2012-01-12 |
2023-08-12 |
human |
| Xiaochun Huang, Xiaolin Li, Ranxin Huang, Xiaogang Yang, Bin F. [Effect of celecoxib and adriamycin on proliferation and apoptosis of Raji cells and its mechanism]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 35. issue 10. 2011-11-28. PMID:21051834. |
to assess the effect of celecoxib in combination with adriamycin(adm) on cell proliferation and apoptosis. |
2011-11-28 |
2023-08-12 |
Not clear |
| Peng Yuang, Bao-An Chen, Jian Cheng, Xu-Dong Ma, De-Long Liu, Quan-Yi L. [Effect of phenylhexyl isothiocyanate on adriamycin resistance of K562/A02 cell line]. Zhongguo shi yan xue ye xue za zhi. vol 17. issue 2. 2011-07-12. PMID:19379565. |
the apoptosis rate of k562/a02 cell line, the changes of intracellular adm concentrations and mrp1 protein level were detected by flow cytometry (fcm). |
2011-07-12 |
2023-08-12 |
Not clear |
| Peng Yuang, Bao-An Chen, Jian Cheng, Xu-Dong Ma, De-Long Liu, Quan-Yi L. [Effect of phenylhexyl isothiocyanate on adriamycin resistance of K562/A02 cell line]. Zhongguo shi yan xue ye xue za zhi. vol 17. issue 2. 2011-07-12. PMID:19379565. |
apoptosis rate increased after treatment in combination with two above drugs, the changes of drug resistance multiple and intracellular adm level had statistical significance between k562/a02 and k562 cells (p < 0.05), when the concentration of phi was more than 20 micromol/l. |
2011-07-12 |
2023-08-12 |
Not clear |
| Zhi-Hua Liu, Yan-Lei Ma, Yan-Ping He, Peng Zhang, Yu-Kun Zhou, Huanlong Qi. Tamoxifen reverses the multi-drug-resistance of an established human cholangiocarcinoma cell line in combined chemotherapeutics. Molecular biology reports. vol 38. issue 3. 2011-05-23. PMID:20835928. |
cell growth inhibition was determined by the mtt assay, while cell cycle progression, apoptosis and the intra-cellular concentration of adriamycin (adm) were all determined by flow cytometry. |
2011-05-23 |
2023-08-12 |
human |
| Zhi-Hua Liu, Yan-Lei Ma, Yan-Ping He, Peng Zhang, Yu-Kun Zhou, Huanlong Qi. Tamoxifen reverses the multi-drug-resistance of an established human cholangiocarcinoma cell line in combined chemotherapeutics. Molecular biology reports. vol 38. issue 3. 2011-05-23. PMID:20835928. |
growth inhibition and apoptosis induced by adm, mitomycin (mmc), or vindesine (vds) were enhanced after pre-treatment with 5 or 10 μm tam, while only vds increased cell numbers in the g(2)/m phase. |
2011-05-23 |
2023-08-12 |
human |
| Ranxin Huang, Xiaolin Li, Xiaochun Huang, Xiaogang Yang, Wenqi L. [Effect of arsenic trioxide combined with adriamycin on the proliferation and apoptosis of human lymphoma cells]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 34. issue 6. 2011-04-28. PMID:19587434. |
to determine the effect of arsenic trioxide combined with adriamycin(adm) on the proliferation and apoptosis of human lymphoma cells. |
2011-04-28 |
2023-08-12 |
human |
| Junichiro Tanaka, Kazushi Sugimoto, Katsuya Shiraki, Masahiko Tameda, Satoko Kusagawa, Keiichiro Nojiri, Tetsuya Beppu, Kentaro Yoneda, Norihiko Yamamoto, Kazuhiko Uchida, Takahiro Kojima, Yoshiyuki Take. Functional cell surface expression of toll-like receptor 9 promotes cell proliferation and survival in human hepatocellular carcinomas. International journal of oncology. vol 37. issue 4. 2010-12-23. PMID:20811701. |
cell surface stimulation of tlr9 promoted cell proliferation, and, furthermore, the tlr9 agonists, cpg-odns, reduced the cytotoxicity of the anti-cancer drug adriamycin (adm) via up-regulation of apoptosis inhibitors such as survivin, bcl-xl, xiap and cflip, in hcc cell lines. |
2010-12-23 |
2023-08-12 |
human |
| Yan Yu, Min Xie, Yu-Lei He, Wang-Qiong Xu, Shan Zhu, Li-Zhi Ca. [Role of high mobility group box 1 in adriamycin-induced apoptosis in leukemia K562 cells]. Ai zheng = Aizheng = Chinese journal of cancer. vol 27. issue 9. 2010-08-31. PMID:18799030. |
this study was to explore the role of hmgb1 in adriamycin (adm)-induced apoptosis in leukemia k562 cells. |
2010-08-31 |
2023-08-12 |
Not clear |
| Min Xie, Rui Kang, Yan Yu, Shan Zhu, Yu-Lei He, Wang-Qiong Xu, Dao-Lin Tang, Li-Zhi Ca. [Enhancive effect of HMGB1 gene silence on adriamycin-induced apoptosis in K562/A02 drug resistance leukemia cells]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. vol 29. issue 8. 2010-04-08. PMID:19112920. |
to investigate the effect of high mobility group boxl (hmgbi) gene silence on adriamycin (adm)-induced apoptosis in k562/a02 drug resistance leukemia cells. |
2010-04-08 |
2023-08-12 |
Not clear |
| D D Cui, Y Huang, S H Mao, S C Chen, M Qiu, L L Ji, C Y. Synergistic antitumor effect of TRAIL and adriamycin on the human breast cancer cell line MCF-7. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 42. issue 9. 2010-03-03. PMID:19738990. |
the aim of the present study was to determine the effect of the combination of tumor necrosis factor-related apoptosis-inducing ligand (trail) and adriamycin (adm) on the human breast cancer cell line mcf-7 and to identify potential mechanisms of apoptosis. |
2010-03-03 |
2023-08-12 |
human |
| D D Cui, Y Huang, S H Mao, S C Chen, M Qiu, L L Ji, C Y. Synergistic antitumor effect of TRAIL and adriamycin on the human breast cancer cell line MCF-7. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 42. issue 9. 2010-03-03. PMID:19738990. |
in addition, the combined treatment with trail and adm significantly increased cell apoptosis from 9.8% (trail) or 17% (adm) to 38.7%, resulting in a synergistic apoptotic effect, which is proposed to be mediated by up-regulation of dr4 and dr5 mrna expression and increased expression of bax and caspase-9 proteins. |
2010-03-03 |
2023-08-12 |
human |
| Guo-rong Bi, Hui Zhang, Hui-jie Zhou, Li-juan Bai, He-min Zhang, Hong Hai, Xiu-bin Fan. [Effect of adrenomedullin on neuron apoptosis and early growth response gene-1 after focal ischemia/ reperfusion in rats]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. vol 19. issue 6. 2009-07-09. PMID:17577444. |
to explore the influence of adrenomedullin (adm) on apoptosis of neuron, volume of infarction and the expression of early growth response gene-1 (egr-1) mrna in the rat with focal ischemia/reperfusion (i/r) injury. |
2009-07-09 |
2023-08-12 |
rat |
| Juan Li, Ying Zhao, Shao-Kai Luo, Dian-Bao Zhang, Bei-Hui Huan. [Effect of silencing survivin gene on sensitivity of myeloma cells to adriamycin]. Ai zheng = Aizheng = Chinese journal of cancer. vol 25. issue 12. 2009-06-09. PMID:17166372. |
this study was designed to use rna interference technique to down-regulate the expression of survivin gene in human myeloma cell line km3, observe its effects on apoptosis of km3 cells and sensitivity of km3 cells to adriamycin (adm). |
2009-06-09 |
2023-08-12 |
human |
| Zhi-Ming Li, Wen-Qi Jiang, Zhen-Yu Zhu, Xiao-feng Zhu, Jun-Min Zhou, Zong-Chao Liu, Da-Jun Yang, Zhong-Zhen Guan. Synergistic cytotoxicity of Bcl-xL inhibitor, gossypol and chemotherapeutic agents in non-Hodgkin's lymphoma cells. Cancer biology & therapy. vol 7. issue 1. 2008-06-10. PMID:17938578. |
our data showed that treatment of ramos cells with gossypol not only induced cell arrest on the g(0)/g(1) phase, but also augmented apoptosis and growth inhibition induced by etoposide (vp-16), doxorubicin hydrochloride (adm), vincristine (vcr), and paclitaxel (taxol). |
2008-06-10 |
2023-08-12 |
Not clear |
| Peng Gao, Chi-hua Fang, Gang-qing Zhang, Zheng Ya. [Antisense oligonucleotide against survivin induces apoptosis and enhances adriamycin sensitivity of SMMC-7721/ADM cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 11. 2008-05-14. PMID:17121723. |
to explore the effects of survivin-specific antisense oligonucleotide (asodn) delivered via liposome on the growth and apoptosis of drug-resistant human hepatic cancer cell line smmc-7721/adm and the sensitivity of the cells to adriamycin (adm). |
2008-05-14 |
2023-08-12 |
human |
| José Manuel Lerma-Díaz, Georgina Hernández-Flores, Jorge R Domínguez-Rodríguez, Pablo C Ortíz-Lazareno, Piedad Gómez-Contreras, Ramón Cervantes-Munguía, Daniel Scott-Algara, Adriana Aguilar-Lemarroy, Luis F Jave-Suárez, Alejandro Bravo-Cuella. In vivo and in vitro sensitization of leukemic cells to adriamycin-induced apoptosis by pentoxifylline. Involvement of caspase cascades and IkappaBalpha phosphorylation. Immunology letters. vol 103. issue 2. 2008-03-14. PMID:16388856. |
the aim of this work was to investigate whether in vivo and in vitro pentoxifylline (ptx) sensitizes hematological tumor cells to adriamycin (adm)-induced apoptosis, and to investigate the involvement of caspase cascades and phosphorylated forms of ikappabalpha. |
2008-03-14 |
2023-08-12 |
mouse |
| José Manuel Lerma-Díaz, Georgina Hernández-Flores, Jorge R Domínguez-Rodríguez, Pablo C Ortíz-Lazareno, Piedad Gómez-Contreras, Ramón Cervantes-Munguía, Daniel Scott-Algara, Adriana Aguilar-Lemarroy, Luis F Jave-Suárez, Alejandro Bravo-Cuella. In vivo and in vitro sensitization of leukemic cells to adriamycin-induced apoptosis by pentoxifylline. Involvement of caspase cascades and IkappaBalpha phosphorylation. Immunology letters. vol 103. issue 2. 2008-03-14. PMID:16388856. |
both cell lines were treated under similar experimental conditions with ptx and/or adm to assess their effects on apoptosis. |
2008-03-14 |
2023-08-12 |
mouse |
| Benjamin Uzan, Aude Villemin, Jean-Michel Garel, Michèle Cressen. Adrenomedullin is anti-apoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway. Journal of cellular physiology. vol 215. issue 1. 2008-02-19. PMID:17941085. |
adrenomedullin (adm) has been shown to mediate multifunctional responses in cell culture and animal system such as regulation of growth and apoptosis. |
2008-02-19 |
2023-08-12 |
mouse |
| Benjamin Uzan, Aude Villemin, Jean-Michel Garel, Michèle Cressen. Adrenomedullin is anti-apoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway. Journal of cellular physiology. vol 215. issue 1. 2008-02-19. PMID:17941085. |
the ability of adm to influence osteoblastic cell number through inhibition of apoptosis has not yet been studied. |
2008-02-19 |
2023-08-12 |
mouse |