| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesco Paneni, Thomas F Lüsche. Cardiovascular Protection in the Treatment of Type 2 Diabetes: A Review of Clinical Trial Results Across Drug Classes. The American journal of medicine. vol 130. issue 6S. 2017-07-03. PMID:28526186. |
the recent trials empagliflozin cardiovascular outcome event trial in type 2 diabetes mellitus patients-removing excess glucose (empa-reg outcome); trial to evaluate cardiovascular and other long-term outcomes with semaglutide in subjects with type 2 diabetes (sustain-6); liraglutide effect and action in diabetes: evaluation of cardiovascular outcome results (leader); and insulin resistance intervention after stroke (iris) have shed some light on this important clinical issue, thus showing a convincing effect of empagliflozin, liraglutide, and pioglitazone on cvd outcomes. |
2017-07-03 |
2023-08-13 |
human |
| Jing Jing, Yuesong Pan, Xingquan Zhao, Huaguang Zheng, Qian Jia, Donghua Mi, Weiqi Chen, Hao Li, Liping Liu, Chunxue Wang, Yan He, David Wang, Yilong Wang, Yongjun Wan. Insulin Resistance and Prognosis of Nondiabetic Patients With Ischemic Stroke: The ACROSS-China Study (Abnormal Glucose Regulation in Patients With Acute Stroke Across China). Stroke. vol 48. issue 4. 2017-05-29. PMID:28235959. |
insulin resistance and prognosis of nondiabetic patients with ischemic stroke: the across-china study (abnormal glucose regulation in patients with acute stroke across china). |
2017-05-29 |
2023-08-13 |
Not clear |
| Jing Jing, Yuesong Pan, Xingquan Zhao, Huaguang Zheng, Qian Jia, Donghua Mi, Weiqi Chen, Hao Li, Liping Liu, Chunxue Wang, Yan He, David Wang, Yilong Wang, Yongjun Wan. Insulin Resistance and Prognosis of Nondiabetic Patients With Ischemic Stroke: The ACROSS-China Study (Abnormal Glucose Regulation in Patients With Acute Stroke Across China). Stroke. vol 48. issue 4. 2017-05-29. PMID:28235959. |
insulin resistance was common in patients with stroke. |
2017-05-29 |
2023-08-13 |
Not clear |
| Silvio E Inzucchi, Karen L Furi. The IRIS (Insulin Resistance Intervention after Stroke) trial: A new perspective on pioglitazone. Journal of diabetes. vol 8. issue 5. 2017-04-18. PMID:27125599. |
the iris (insulin resistance intervention after stroke) trial: a new perspective on pioglitazone. |
2017-04-18 |
2023-08-13 |
Not clear |
| Evan L O'Keefe, James J DiNicolantonio, Harshal Patil, John H Helzberg, Carl J Lavi. Lifestyle Choices Fuel Epidemics of Diabetes and Cardiovascular Disease Among Asian Indians. Progress in cardiovascular diseases. vol 58. issue 5. 2017-04-10. PMID:26277705. |
due to the rapid pace of urbanization and modernization fueling population growth, in conjunction with a genetic predisposition to insulin resistance, india is suffering a rising epidemic of non-communicable diseases (ncds), including coronary artery disease (cad), type 2 diabetes mellitus (t2dm), and stroke. |
2017-04-10 |
2023-08-13 |
Not clear |
| Estifanos Baye, Barbara Ukropcova, Jozef Ukropec, Alan Hipkiss, Giancarlo Aldini, Barbora de Courte. Physiological and therapeutic effects of carnosine on cardiometabolic risk and disease. Amino acids. vol 48. issue 5. 2017-03-02. PMID:26984320. |
carnosine, traditionally used in exercise physiology to increase exercise performance, has potential preventative and therapeutic benefits in obesity, insulin resistance, t2dm and diabetic microvascular and macrovascular complications (cvd and stroke) as well as number of neurological and mental health conditions. |
2017-03-02 |
2023-08-13 |
Not clear |
| Xin-Yang Yu, Ying Li, Tiemin Liu, Rui-Tao Wan. Association of whole blood viscosity with non-alcoholic fatty liver disease. Clinical hemorheology and microcirculation. vol 62. issue 4. 2017-02-13. PMID:26444605. |
moreover, increased viscosity is observed in insulin resistance, metabolic syndrome, hypertension, diabetes, ischemic heart disease, and stroke. |
2017-02-13 |
2023-08-13 |
Not clear |
| Wen-Ying Chen, Frank Chiahung Mao, Chia-Hsin Liu, Yu-Hsiang Kuan, Nai-Wei Lai, Chih-Cheng Wu, Chun-Jung Che. Chromium supplementation improved post-stroke brain infarction and hyperglycemia. Metabolic brain disease. vol 31. issue 2. 2017-01-10. PMID:26477944. |
stroke rats developed brain infarction, hyperglycemia, hyperinsulinemia, glucose intolerance, and insulin resistance. |
2017-01-10 |
2023-08-13 |
rat |
| Ezio Faglia, Giacomo Clerici, Robert Frykberg, Maurizio Caminiti, Vincenzo Curci, Francesco Cetta, Vincenzo Prisco, Rosaria Greco, Marco Prisco, Alberto Morabit. Outcomes of Chopart Amputation in a Tertiary Referral Diabetic Foot Clinic: Data From a Consecutive Series of 83 Hospitalized Patients. The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons. vol 55. issue 2. 2016-12-13. PMID:26620421. |
of the 83 patients, 26 were female, 61 required insulin, 47 had renal insufficiency, 19 underwent hemodialysis, 65 had hypertension, 34 had a history of cardiac disease, and 4 had a history of stroke. |
2016-12-13 |
2023-08-13 |
Not clear |
| James S Floyd, Kerri L Wiggins, Mark Christiansen, Sascha Dublin, William T Longstreth, Nicholas L Smith, Barbara McKnight, Susan R Heckbert, Noel S Weiss, Bruce M Psat. Case-control study of oral glucose-lowering drugs in combination with long-acting insulin and the risks of incident myocardial infarction and incident stroke. Pharmacoepidemiology and drug safety. vol 25. issue 2. 2016-10-24. PMID:26547662. |
case-control study of oral glucose-lowering drugs in combination with long-acting insulin and the risks of incident myocardial infarction and incident stroke. |
2016-10-24 |
2023-08-13 |
Not clear |
| James S Floyd, Kerri L Wiggins, Mark Christiansen, Sascha Dublin, William T Longstreth, Nicholas L Smith, Barbara McKnight, Susan R Heckbert, Noel S Weiss, Bruce M Psat. Case-control study of oral glucose-lowering drugs in combination with long-acting insulin and the risks of incident myocardial infarction and incident stroke. Pharmacoepidemiology and drug safety. vol 25. issue 2. 2016-10-24. PMID:26547662. |
among users of long-acting insulin, we conducted a population-based case-control study to evaluate the incident myocardial infarction (mi) and incident stroke risks associated with the use of sulfonylureas and the use of metformin. |
2016-10-24 |
2023-08-13 |
Not clear |
| Tushar P Patel, Komal Rawal, Ashim K Bagchi, Gauri Akolkar, Nathalia Bernardes, Danielle da Silva Dias, Sarita Gupta, Pawan K Singa. Insulin resistance: an additional risk factor in the pathogenesis of cardiovascular disease in type 2 diabetes. Heart failure reviews. vol 21. issue 1. 2016-10-12. PMID:26542377. |
insulin resistance (ir) leads to micro or macro angiopathy, peripheral arterial dysfunction, hampered blood flow, hypertension, as well as the cardiomyocyte and the endothelial cell dysfunctions, thus increasing risk factors for coronary artery blockage, stroke and heart failure suggesting that there is a strong association between ir and cvds. |
2016-10-12 |
2023-08-13 |
Not clear |
| Marcio Francisco Lehmann, Ana Paula Kallaur, Sayonara Rangel Oliveira, Daniela Frizon Alfieri, Franciele Delongui, Johnathan de Sousa Parreira, Maria Caroline Martins de Araújo, Carolina Rossato, Jéssica Tavares de Almeida, Larissa Moliterno Pelegrino, Erick Frank Bragato, Ana Lucia Cruz Fürstenberger Lehmann, Helena Kaminami Morimoto, Marcell Alysson Batisti Lozovoy, Andrea Name Colado Simão, Damácio Ramon Kaimen-Maciel, Edna Maria Vissoci Reich. Inflammatory and metabolic markers and short-time outcome in patients with acute ischemic stroke in relation to TOAST subtypes. Metabolic brain disease. vol 30. issue 6. 2016-08-23. PMID:26359121. |
when stroke subtypes were compared, insulin was higher in laas vs. lac and in lac vs. cei (p < 0.05); and tc was lower in laas vs. lac (p < 0.05). |
2016-08-23 |
2023-08-13 |
Not clear |
| J S Floyd, K L Wiggins, C M Sitlani, J H Flory, S Dublin, N L Smith, S R Heckbert, B M Psat. Case-control study of second-line therapies for type 2 diabetes in combination with metformin and the comparative risks of myocardial infarction and stroke. Diabetes, obesity & metabolism. vol 17. issue 12. 2016-08-15. PMID:26179389. |
we conducted a population-based case-control study to assess the myocardial infarction (mi) and stroke risks associated with sulphonylureas and insulin when used in combination with metformin. |
2016-08-15 |
2023-08-13 |
Not clear |
| J S Floyd, K L Wiggins, C M Sitlani, J H Flory, S Dublin, N L Smith, S R Heckbert, B M Psat. Case-control study of second-line therapies for type 2 diabetes in combination with metformin and the comparative risks of myocardial infarction and stroke. Diabetes, obesity & metabolism. vol 17. issue 12. 2016-08-15. PMID:26179389. |
cases had type 2 diabetes and used metformin + insulin or metformin + sulphonylureas at the time of a first mi or first stroke between 1995 and 2010; controls used the same treatment combinations and were randomly sampled from the same population. |
2016-08-15 |
2023-08-13 |
Not clear |
| J S Floyd, K L Wiggins, C M Sitlani, J H Flory, S Dublin, N L Smith, S R Heckbert, B M Psat. Case-control study of second-line therapies for type 2 diabetes in combination with metformin and the comparative risks of myocardial infarction and stroke. Diabetes, obesity & metabolism. vol 17. issue 12. 2016-08-15. PMID:26179389. |
compared with metformin + sulphonylurea, metformin + insulin was associated with similar risks of mi or stroke [odds ratio 0.98 (95% confidence interval 0.63-1.52)]. |
2016-08-15 |
2023-08-13 |
Not clear |
| K J Mather, G D Hutchins, K Perry, W Territo, R Chisholm, A Acton, B Glick-Wilson, R V Considine, S Moberly, T R DeGrad. Assessment of myocardial metabolic flexibility and work efficiency in human type 2 diabetes using 16-[18F]fluoro-4-thiapalmitate, a novel PET fatty acid tracer. American journal of physiology. Endocrinology and metabolism. vol 310. issue 6. 2016-08-02. PMID:26732686. |
insulin augmented heart rate, blood pressure, and stroke index in both groups (all p < 0.01) and significantly increased myocardial oxygen consumption (p = 0.04) and perfusion (p = 0.01) in both groups. |
2016-08-02 |
2023-08-13 |
human |
| Neil F Goodman, Rhoda H Cobin, Walter Futterweit, Jennifer S Glueck, Richard S Legro, Enrico Carmin. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ANDROGEN EXCESS AND PCOS SOCIETY DISEASE STATE CLINICAL REVIEW: GUIDE TO THE BEST PRACTICES IN THE EVALUATION AND TREATMENT OF POLYCYSTIC OVARY SYNDROME - PART 2. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. vol 21. issue 12. 2016-07-29. PMID:26642102. |
given the association with insulin resistance, all women with pcos require evaluation for the risk of metabolic syndrome (mets) and its components, including type 2 diabetes, hypertension, hyperlipidemia, and the possible risk of clinical events, including acute myocardial infarction and stroke. |
2016-07-29 |
2023-08-13 |
human |
| Uwe Gröber, Joachim Schmidt, Klaus Kister. Magnesium in Prevention and Therapy. Nutrients. vol 7. issue 9. 2016-06-29. PMID:26404370. |
low levels of magnesium have been associated with a number of chronic diseases, such as alzheimer's disease, insulin resistance and type-2 diabetes mellitus, hypertension, cardiovascular disease (e.g., stroke), migraine headaches, and attention deficit hyperactivity disorder (adhd). |
2016-06-29 |
2023-08-13 |
human |
| Sarbashri Bank, Suman Bhattacharya, Smarajit Maiti, Raja Bhattacharya, Debajyoti Chakraborty, Asru K Sinh. The impaired synthesis of insulin and its inability to inhibit platelet aggregation in cerebrovascular accident. Metabolic brain disease. vol 30. issue 5. 2016-06-24. PMID:26188955. |
as diabetes mellitus is a risk factor for strokes and insulin is reported to prevent thrombosis, the role of insulin in is and hs was investigated. |
2016-06-24 |
2023-08-13 |
mouse |