| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Colin D Chapman, William H Frey, Suzanne Craft, Lusine Danielyan, Manfred Hallschmid, Helgi B Schiöth, Christian Benedic. Intranasal treatment of central nervous system dysfunction in humans. Pharmaceutical research. vol 30. issue 10. 2014-03-21. PMID:23135822. |
thus, for a variety of growth factors, hormones, neuropeptides and therapeutics including insulin, oxytocin, orexin, and even stem cells, intranasal delivery is emerging as an efficient method of administration, and represents a promising therapeutic strategy for the treatment of diseases with cns involvement, such as obesity, alzheimer's disease, parkinson's disease, huntington's disease, depression, anxiety, autism spectrum disorders, seizures, drug addiction, eating disorders, and stroke. |
2014-03-21 |
2023-08-12 |
Not clear |
| M Zemba, Corina Ioana Avram, Uliana Ochinciuc, Alina Cristina Stamate, Raluca Lăcrămioara Cambur. [Ocular ischemic syndrome--a case report]. Oftalmologia (Bucharest, Romania : 1990). vol 57. issue 2. 2014-03-14. PMID:24386788. |
the case we present is of an 63 years old man known with primary arterial hypertension, hypercholesterolemia, diabetes type 2 non insulin dependent and diagnosticated with ischemic cerebral stroke and bilateral obstruction of internal carotid arteries in march 2010, who is presenting for visual impairment in both eyes. |
2014-03-14 |
2023-08-12 |
Not clear |
| C G Souza, B P Riboldi, F Hansen, J D Moreira, D G Souza, A M de Assis, L M Brum, M L S Perry, D O Souz. Chronic sulforaphane oral treatment accentuates blood glucose impairment and may affect GLUT3 expression in the cerebral cortex and hypothalamus of rats fed with a highly palatable diet. Food & function. vol 4. issue 8. 2014-02-06. PMID:23797263. |
obesity and insulin resistance are the key factors underlying the etiology of major health problems such as hypertension, diabetes and stroke. |
2014-02-06 |
2023-08-12 |
rat |
| Kelly A Tennant, Craig E Brow. Diabetes augments in vivo microvascular blood flow dynamics after stroke. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 49. 2014-01-31. PMID:24305815. |
treating diabetic mice with insulin immediately after stroke resulted in less severe alterations in blood flow within the first 7 d of recovery, but had more variable results at later time points. |
2014-01-31 |
2023-08-12 |
mouse |
| Justine Devos, André Peeters, Xavier Wittebole, Philippe Hantso. High-dose insulin therapy for neurogenic-stunned myocardium after stroke. BMJ case reports. vol 2012. 2014-01-21. PMID:23175002. |
high-dose insulin therapy for neurogenic-stunned myocardium after stroke. |
2014-01-21 |
2023-08-12 |
Not clear |
| Ahter D Sanlioglu, Hasan Ali Altunbas, Mustafa Kemal Balci, Thomas S Griffith, Salih Sanliogl. Clinical utility of insulin and insulin analogs. Islets. vol 5. issue 2. 2014-01-17. PMID:23584214. |
despite the evidence of early insulin treatment lowering macrovascular (coronary artery disease, peripheral arterial disease and stroke) and microvascular (diabetic nephropathy, neuropathy and retinopathy) complications of t2dm, controversy exists among physicians on how to initiate and intensify insulin therapy. |
2014-01-17 |
2023-08-12 |
human |
| Irene A Munro, Manohar L Gar. Dietary supplementation with long chain omega-3 polyunsaturated fatty acids and weight loss in obese adults. Obesity research & clinical practice. vol 7. issue 3. 2013-12-30. PMID:23697585. |
obesity is associated with elevated levels of inflammation and metabolic abnormalities, with increased risk of developing insulin resistance, type 2 diabetes, stroke and cvd. |
2013-12-30 |
2023-08-12 |
Not clear |
| Radosław Bienek, Bogdan Marek, Dariusz Kajdaniuk, Halina Borgiel-Marek, Tomasz Piecha, Mariusz Nowak, Lucyna Siemińska, Joanna Głogowska-Szeląg, Wanda Foltyn, Beata Kos-Kudł. Adiponectin, leptin, resistin and insulin blood concentrations in patients with ischaemic cerebral stroke. Endokrynologia Polska. vol 63. issue 5. 2013-12-05. PMID:23115066. |
adiponectin, leptin, resistin and insulin blood concentrations in patients with ischaemic cerebral stroke. |
2013-12-05 |
2023-08-12 |
human |
| Eric Vounsia Balti, André Pascal Kengne, Jean Valentin Fogha Fokouo, Brice Enid Nouthé, Eugene Sobngw. Metabolic syndrome and fatal outcomes in the post-stroke event: a 5-year cohort study in Cameroon. PloS one. vol 8. issue 4. 2013-10-30. PMID:23565192. |
we assessed the association of metabolic syndrome (mets) and insulin resistance with post-stroke mortality in patients with first-ever-in-lifetime stroke in the capital city of cameroon (sub-saharan africa). |
2013-10-30 |
2023-08-12 |
Not clear |
| Ya-Yu Wang, Chun-Jung Chen, Shih-Yi Lin, Yu-Han Chuang, Wayne Huey-Herng Sheu, Kwong-Chung Tun. Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia. Molecular and cellular endocrinology. vol 367. issue 1-2. 2013-09-26. PMID:23279876. |
in the acute phase of stroke (within 24h), rats with permanent cerebral ischemia developed higher fasting blood glucose and insulin levels in association with up-regulation of hepatic gluconeogenic gene expression, including phosphoenolpyruvate carboxykinase, glucose-6-phosphatase, and fructose-1,6-bisphosphatase. |
2013-09-26 |
2023-08-12 |
rat |
| Aleksandra Jotic, Nadezda Covickovic Sternic, Vladimir S Kostic, Katarina Lalic, Tanja Milicic, Milija Mijajlovic, Ljiljana Lukic, Milorad Civcic, Emina Colak, Marija Macesic, Jelena P Seferovic, Sandra Aleksic, Nebojsa M Lali. Type 2 diabetic patients with ischemic stroke: decreased insulin sensitivity and decreases in antioxidant enzyme activity are related to different stroke subtypes. International journal of endocrinology. vol 2013. 2013-07-11. PMID:23843789. |
type 2 diabetic patients with ischemic stroke: decreased insulin sensitivity and decreases in antioxidant enzyme activity are related to different stroke subtypes. |
2013-07-11 |
2023-08-12 |
Not clear |
| Aleksandra Jotic, Nadezda Covickovic Sternic, Vladimir S Kostic, Katarina Lalic, Tanja Milicic, Milija Mijajlovic, Ljiljana Lukic, Milorad Civcic, Emina Colak, Marija Macesic, Jelena P Seferovic, Sandra Aleksic, Nebojsa M Lali. Type 2 diabetic patients with ischemic stroke: decreased insulin sensitivity and decreases in antioxidant enzyme activity are related to different stroke subtypes. International journal of endocrinology. vol 2013. 2013-07-11. PMID:23843789. |
we analyzed (a) insulin sensitivity (is) and (b) glutathione peroxidase (gsh-px), glutathione reductase (gr), and superoxide dismutase (sod) antioxidant enzyme activity in type 2 diabetic (t2d) patients with atherothrombotic infarction (ati) (group a), lacunar infarction (li) (b), or without stroke (c) and in nondiabetics with ati (d), li (e), or without stroke (f). |
2013-07-11 |
2023-08-12 |
Not clear |
| Ayca Ozkul, Mediha Ayhan, Ali Akyol, Eylem Telli Turgut, Gurhan Kadikoylu, Cigdem Yenise. The effect of insulin resistance on inflammatory response and oxidative stress in acute cerebral ischemia. Neuro endocrinology letters. vol 34. issue 1. 2013-06-20. PMID:23524624. |
insulin resistance (ir) has effects on inflammation and oxidative stress which have importance in acute stroke. |
2013-06-20 |
2023-08-12 |
Not clear |
| G Barone-Rochette, G Vanzetto, O Detante, P-Y Benhamou, S Halimi, M Hommel, J-M Mallion, J-P Bague. Metabolic disturbances after acute vascular events: a comparative study of acute coronary syndrome and ischaemic atherothrombotic stroke. Diabetes & metabolism. vol 38. issue 6. 2013-05-07. PMID:23062594. |
this pilot study aimed to compare metabolic disturbances, particularly insulin resistance (ir) and cardiovascular risk factors (crfs), following two types of acute vascular atherothrombotic disease events: ischaemic atherothrombotic stroke (as); and acute coronary syndrome (acs). |
2013-05-07 |
2023-08-12 |
Not clear |
| Eugene Sobngwi, Andre-Pascal Kengne, Eric Vounsia Balti, Leopold Fezeu, Brice Nouthe, Sephirin Djiogue, Dieudonne Njamen, Jean-François Gautier, Nigel C Unwin, Jean-Claude Mbany. Metabolic profile of sub-Saharan African patients presenting with first-ever-in-lifetime stroke: association with insulin resistance. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 21. issue 8. 2013-04-23. PMID:21683619. |
metabolic profile of sub-saharan african patients presenting with first-ever-in-lifetime stroke: association with insulin resistance. |
2013-04-23 |
2023-08-12 |
Not clear |
| Shawn B Bender, Adam P McGraw, Iris Z Jaffe, James R Sower. Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease? Diabetes. vol 62. issue 2. 2013-04-11. PMID:23349535. |
patients with diabetes and/or the metabolic syndrome have a significantly increased risk of heart attack and stroke compared with people with normal insulin sensitivity. |
2013-04-11 |
2023-08-12 |
Not clear |
| J C K Well. Ethnic variability in adiposity, thrifty phenotypes and cardiometabolic risk: addressing the full range of ethnicity, including those of mixed ethnicity. Obesity reviews : an official journal of the International Association for the Study of Obesity. vol 13 Suppl 2. 2013-01-03. PMID:23107256. |
a conceptual model is proposed, treating insulin sensitivity and stroke risk as composite functions of body composition variables. |
2013-01-03 |
2023-08-12 |
Not clear |
| Renske G Wieberdink, Peter J Koudstaal, Albert Hofman, Jacqueline C M Witteman, Monique M B Breteler, M Arfan Ikra. Insulin resistance and the risk of stroke and stroke subtypes in the nondiabetic elderly. American journal of epidemiology. vol 176. issue 8. 2012-12-31. PMID:23035021. |
insulin resistance and the risk of stroke and stroke subtypes in the nondiabetic elderly. |
2012-12-31 |
2023-08-12 |
human |
| Renske G Wieberdink, Peter J Koudstaal, Albert Hofman, Jacqueline C M Witteman, Monique M B Breteler, M Arfan Ikra. Insulin resistance and the risk of stroke and stroke subtypes in the nondiabetic elderly. American journal of epidemiology. vol 176. issue 8. 2012-12-31. PMID:23035021. |
insulin resistance, which plays a key role in the development of diabetes mellitus, is a putative modifiable risk factor for stroke. |
2012-12-31 |
2023-08-12 |
human |
| Renske G Wieberdink, Peter J Koudstaal, Albert Hofman, Jacqueline C M Witteman, Monique M B Breteler, M Arfan Ikra. Insulin resistance and the risk of stroke and stroke subtypes in the nondiabetic elderly. American journal of epidemiology. vol 176. issue 8. 2012-12-31. PMID:23035021. |
the aim of this study was to investigate if markers of insulin resistance were associated with risk of stroke in the general elderly population. |
2012-12-31 |
2023-08-12 |
human |