| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Song Zhang, Yuanteng Fan, Xiaojian Cao, Chunchu Deng, Jia Xu, Qiuzhi Zhou, Yajie Li, Yatao Yin, Hong Che. Treadmill exercise improves cerebral ischemia injury by regulating microglia polarization via downregulation of MMP12. International immunopharmacology. vol 142. issue Pt B. 2024-09-28. PMID:39340990. |
exercise training is the main strategy for stroke rehabilitation, and it has shown that shifting microglia toward m2 phenotype is beneficial for the recovery of neurological function after stroke. |
2024-09-28 |
2024-10-01 |
Not clear |
| Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xian. Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model European journal of histochemistry : EJH. vol 68. issue 3. 2024-09-17. PMID:39287134. |
propofol alleviates m1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model subarachnoid hemorrhage (sah) is a devastating stroke caused by ruptured intracranial aneurysms, leading to blood accumulation around the brain. |
2024-09-17 |
2024-09-20 |
Not clear |
| Wei Wei, Seyed Siyawasch Justus Lattau, Wenqiang Xin, Yongli Pan, Lars Tatenhorst, Lin Zhang, Irina Graf, Yaoyun Kuang, Xuan Zheng, Zhongnan Hao, Aurel Popa-Wagner, Stefan T Gerner, Sabine Huber, Manuel Nietert, Christian Klose, Ertugrul Kilic, Dirk M Hermann, Mathias Bähr, Hagen B Huttner, Hua Liu, Dirk Fitzner, Thorsten R Doeppne. Dynamic Brain Lipid Profiles Modulate Microglial Lipid Droplet Accumulation and Inflammation Under Ischemic Conditions in Mice. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-09-10. PMID:39252446. |
however, the role of ld-rich microglia (ldrm) under stroke conditions is unknown. |
2024-09-10 |
2024-09-13 |
mouse |
| Wei Wei, Seyed Siyawasch Justus Lattau, Wenqiang Xin, Yongli Pan, Lars Tatenhorst, Lin Zhang, Irina Graf, Yaoyun Kuang, Xuan Zheng, Zhongnan Hao, Aurel Popa-Wagner, Stefan T Gerner, Sabine Huber, Manuel Nietert, Christian Klose, Ertugrul Kilic, Dirk M Hermann, Mathias Bähr, Hagen B Huttner, Hua Liu, Dirk Fitzner, Thorsten R Doeppne. Dynamic Brain Lipid Profiles Modulate Microglial Lipid Droplet Accumulation and Inflammation Under Ischemic Conditions in Mice. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-09-10. PMID:39252446. |
hence, microglia display enhanced levels of ld accumulation and elevated perilipin 2 (plin2) expression patterns when exposed to hypoxia or stroke. |
2024-09-10 |
2024-09-13 |
mouse |
| Yan Huang, Shuang Li, Yuhan Yang, Kunyi Li, Lan Wen, Jinglun L. Chemerin 15 peptide reduces neuroinflammation via the ChemR23 receptor after ischemia-reperfusion injury. Neural regeneration research. 2024-09-09. PMID:39248165. |
however, its effects on microglia and stroke remain unclear. |
2024-09-09 |
2024-09-11 |
mouse |
| Yuhua Chen, Wei He, Junlin Qiu, Yangyang Luo, Chenlong Jiang, Feng Zhao, Hong Wei, Jiao Meng, Tianlin Long, Xin Zhang, Lingjian Yang, Quanhua Xu, Juning Wang, Chi Zhan. Pterostilbene improves neurological dysfunction and neuroinflammation after ischaemic stroke via HDAC3/Nrf1-mediated microglial activation. Cellular & molecular biology letters. vol 29. issue 1. 2024-08-29. PMID:39198723. |
further elucidation of factors that regulate microglia and nuclear factor (erythroid-derived 2)-like 1 (nrf1) may lead to a promising strategy for treating neuroinflammation after ischaemic stroke. |
2024-08-29 |
2024-09-01 |
Not clear |
| Raffaela Cipriani, Maria Domerq, Abraham Martín, Carlos Matut. Role of Microglia in Stroke. Advances in neurobiology. vol 37. 2024-08-29. PMID:39207705. |
role of microglia in stroke. |
2024-08-29 |
2024-09-04 |
Not clear |
| Raffaela Cipriani, Maria Domerq, Abraham Martín, Carlos Matut. Role of Microglia in Stroke. Advances in neurobiology. vol 37. 2024-08-29. PMID:39207705. |
activated microglia are one of the most important cellular components of poststroke inflammation, appearing from the first few hours and persisting for days and weeks after stroke injury. |
2024-08-29 |
2024-09-04 |
Not clear |
| Santra Brenna, Markus Glatzel, Tim Magnus, Berta Puig, Giovanna Galliciott. Neuroserpin and Extracellular Vesicles in Ischemic Stroke: Partners in Neuroprotection? Aging and disease. vol 15. issue 5. 2024-08-27. PMID:39191396. |
conversely, ns-deficient animals exhibit larger stroke injury, increased bbb permeability and enhanced microglia activation. |
2024-08-27 |
2024-08-30 |
Not clear |
| Eric Yuhsiang Wang, Hank Szuhan Chen, Meng-Chih Wu, Ya Lan Yang, Hwai-Lee Wang, Che-Wei Liu, Ted Weita La. Microglia through MFG-E8 signaling decrease the density of degenerating neurons and protect the brain from the development of cortical infarction after stroke. PloS one. vol 19. issue 8. 2024-08-07. PMID:39110702. |
microglia through mfg-e8 signaling decrease the density of degenerating neurons and protect the brain from the development of cortical infarction after stroke. |
2024-08-07 |
2024-08-10 |
mouse |
| Eric Yuhsiang Wang, Hank Szuhan Chen, Meng-Chih Wu, Ya Lan Yang, Hwai-Lee Wang, Che-Wei Liu, Ted Weita La. Microglia through MFG-E8 signaling decrease the density of degenerating neurons and protect the brain from the development of cortical infarction after stroke. PloS one. vol 19. issue 8. 2024-08-07. PMID:39110702. |
neuronal loss is a hallmark of stroke and other neurodegenerative diseases, and as such, neuronal loss caused by microglia has been thought to be a contributing factor to disease progression. |
2024-08-07 |
2024-08-10 |
mouse |
| Eric Yuhsiang Wang, Hank Szuhan Chen, Meng-Chih Wu, Ya Lan Yang, Hwai-Lee Wang, Che-Wei Liu, Ted Weita La. Microglia through MFG-E8 signaling decrease the density of degenerating neurons and protect the brain from the development of cortical infarction after stroke. PloS one. vol 19. issue 8. 2024-08-07. PMID:39110702. |
in both scenarios, the effects were microglia specific, as the same treatments had no effect in mice whose microglia were depleted prior to stroke. |
2024-08-07 |
2024-08-10 |
mouse |
| Eric Yuhsiang Wang, Hank Szuhan Chen, Meng-Chih Wu, Ya Lan Yang, Hwai-Lee Wang, Che-Wei Liu, Ted Weita La. Microglia through MFG-E8 signaling decrease the density of degenerating neurons and protect the brain from the development of cortical infarction after stroke. PloS one. vol 19. issue 8. 2024-08-07. PMID:39110702. |
in conclusion, microglia through mfg-e8 signaling contribute to the loss of ischemic neurons and, in doing so, minimize the development of cortical infarction after stroke. |
2024-08-07 |
2024-08-10 |
mouse |
| Ángela Del Águila, Ran Zhang, Xinyuan Yu, Lihong Dang, Feng Xu, Jin Zhang, Vaibhav Jain, Jilin Tian, Xiao-Ping Zhong, Huaxin Sheng, Wei Yan. Microglial heterogeneity in the ischemic stroke mouse brain of both sexes. Genome medicine. vol 16. issue 1. 2024-08-03. PMID:39095897. |
the objective of the current study was to dissect the effect of permanent stroke on microglia, the resident immune cells within the brain parenchyma. |
2024-08-03 |
2024-08-06 |
mouse |
| Xiuping Li, Jingyang Shan, Xia Liu, Zhengzheng Huang, Gelin Xu, Lijie Re. Microglial repopulation induced by PLX3397 protects against ischemic brain injury by suppressing neuroinflammation in aged mice. International immunopharmacology. vol 138. 2024-06-29. PMID:38943977. |
although studies have demonstrated the inflammatory profile of aged microglia in several neurological diseases, this issue is largely uncertain in stroke. |
2024-06-29 |
2024-07-02 |
mouse |
| Heidi Harjunpää, Robert Tallberg, Yunhao Cui, Carla Guenther, Hock-Kean Liew, Anna Seelbach, Guillem Saldo Rubio, Mikko Airavaara, Susanna C Fagerhol. β2-Integrins Regulate Microglial Responses and the Functional Outcome of Hemorrhagic Stroke In Vivo. Journal of immunology (Baltimore, Md. : 1950). 2024-06-26. PMID:38921973. |
depending on their phenotype, microglia, the main leukocytes in the cns, are capable of either causing further tissue damage or promoting brain restoration after stroke. |
2024-06-26 |
2024-06-29 |
mouse |
| Lin-Yan Huang, Yi-De Zhang, Jie Chen, Hai-Di Fan, Wan Wang, Bin Wang, Ju-Yun Ma, Peng-Peng Li, Hai-Wei Pu, Xin-Yian Guo, Jian-Gang Shen, Su-Hua Q. Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke. Neural regeneration research. vol 20. issue 3. 2024-06-18. PMID:38886957. |
we found that in the early stage (within 24 hours) of ischemic stroke, neutrophils produced a large amount of hypochlorous acid, while in the recovery phase (10 days after stroke), microglia were activated and produced a small amount of hypochlorous acid. |
2024-06-18 |
2024-06-21 |
rat |
| Flavia Semida Ghinea, Marius Viorel Ionică, Ilona Mihaela Liliac, Simion Pătru, Denisa Greta Olaru, Aurel Popa-Wagne. The Impact of Juvenile Microglia Transcriptomics on the Adult Brain Regeneration after Cerebral Ischemia. Current health sciences journal. vol 50. issue 1. 2024-06-08. PMID:38846476. |
following a stroke in the adult brain, inflammation, neurodegeneration, or disruptions in neural equilibrium trigger alterations in both the genetic blueprint and the structure and roles of microglia, a state often described as "activated" microglia. |
2024-06-08 |
2024-06-10 |
Not clear |
| Yuan Zhao, Wenzhe Sun, Qinlin Fan, Yanjie Huang, Yufan Ma, Shuang Zhang, Changxiong Gong, Bingqiao Wang, Wanyun Zhang, Qingwu Yang, Sen Li. Exploring the potential molecular intersection of stroke and major depression disorder. Biochemical and biophysical research communications. vol 720. 2024-05-17. PMID:38759300. |
single-cell sequencing analysis indicated that mlkl and nlrp3 are mainly influential on endothelial cells and microglia, suggesting that the impairment of these two cell types may be a factor in the relationship between stroke and major depression. |
2024-05-17 |
2024-05-27 |
mouse |
| Weizhuo Lu, Yilin Wang, Jiyue We. The Roles of RhoA/ROCK/NF-κB Pathway in Microglia Polarization Following Ischemic Stroke. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 19. issue 1. 2024-05-16. PMID:38753217. |
on the contrary, anti-inflammatory microglia facilitate recovery following stroke. |
2024-05-16 |
2024-05-27 |
Not clear |