All Relations between Stroke and apoptosis

Publication Sentence Publish Date Extraction Date Species
Zifu Li, Tianxiang Gao, Jing Wang, Xiaoxi Zhang, Yongxin Zhang, Lei Zhang, Pengfei Yang, Jianmin Li. Ferroptosis mediated by TNFSF9 interferes in acute ischaemic stroke reperfusion injury with the progression of acute ischaemic stroke. Journal of neurochemistry. 2024-02-12. PMID:38344886. we first examined tnfsf9 changes in peripheral blood from stroke patients with successful reperfusion, and constructed oxygen-glucose deprivation-reperfusion (ogd-r) on bv2 microglia, oxygen-glucose deprivation for 6 h followed by reoxygenation and re-glucose for 24 h, and appropriate over-expression or knockdown of tnfsf9 manipulation on bv2 cells and found that in the case of bv2 cells encountering ogd-r over-expression of tnfsf9 resulted in increased bv2 apoptosis. 2024-02-12 2024-02-15 mouse
Rehnuma Islam, Jan-Eric Ahlfors, Ricky Siu, Humna Noman, Roya Akbary, Cindi M Morshea. Inhibition of Apoptosis in a Model of Ischemic Stroke Leads to Enhanced Cell Survival, Endogenous Neural Precursor Cell Activation and Improved Functional Outcomes. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339065. apoptosis inhibitors demonstrate efficacy in improving neuronal cell survival in animal models of stroke. 2024-02-10 2024-02-12 mouse
Antoine Beurton, Maxime Michot, François-Xavier Hérion, Mario Rienzo, Claire Oddos, Thierry Couffinhal, Julien Imbault, Alexandre Ouattar. Systemic Hemodynamics, Cardiac Mechanics, and Signaling Pathways Induced by Extracorporeal Membrane Oxygenation in a Cardiogenic Shock Model. ASAIO journal (American Society for Artificial Internal Organs : 1992). 2024-01-23. PMID:38261663. venoarterial extracorporeal membrane oxygenation may also increase myocardial wall stress and stroke work, possibly affecting the cellular cardioprotective and apoptosis signaling pathways, and thus the infarct size. 2024-01-23 2024-01-26 Not clear
Dina M Mahmoud, Mohammed R A Ali, Basmah Nasser Aldosari, Randa Mohammed Zaki, Obaid Afzal, Alaa S Tulbah, Demiana M Naguib, Mohamed I Zanaty, Mary Eskander Attia, Fatma I Abo El-Ela, Amr Gamal Foua. Functional candesartan loaded lipid nanoparticles for the control of diabetes-associated stroke: In vitro International journal of pharmaceutics: X. vol 7. 2024-01-23. PMID:38260917. candesartan has been used to prevent stroke due to its inhibitory effects on blood pressure, angiogenesis, oxidative damage, and apoptosis. 2024-01-23 2024-01-25 rat
BioMed Research Internationa. Retracted: Influence of miR-1 on Nerve Cell Apoptosis in Rats with Cerebral Stroke via Regulating ERK Signaling Pathway. BioMed research international. vol 2024. 2024-01-17. PMID:38230012. retracted: influence of mir-1 on nerve cell apoptosis in rats with cerebral stroke via regulating erk signaling pathway. 2024-01-17 2024-01-19 rat
Xin Gao, Gang Su, Miao Chai, Minghui Shen, Zhenzhen Hu, Wei Chen, Juan Gao, Ruixin Li, Tianfei Ma, Yang An, Zhenchang Zhan. Research progress on mechanisms of ischemic stroke: Regulatory pathways involving Microglia. Neurochemistry international. 2023-12-11. PMID:38081419. activated microglia participate in the pathological processes after stroke through polarization, autophagy, phagocytosis, pyroptosis, ferroptosis, apoptosis, and necrosis, thereby influencing the injury and repair following stroke. 2023-12-11 2023-12-17 Not clear
Chujuan Liu, Hui Chen, Xi Tao, Chen Li, Aiping Li, Wen W. ALKBH5 protects against stroke by reducing endoplasmic reticulum stress-dependent inflammation injury via the STAT5/PERK/EIF2α/CHOP signaling pathway in an m Experimental neurology. 2023-12-06. PMID:38056583. alkbh5 protects against stroke by reducing endoplasmic reticulum stress-dependent inflammation injury via the stat5/perk/eif2α/chop signaling pathway in an m endoplasmic reticulum (er) stress causes neuroinflammation and neuronal apoptosis during ischemic stroke progression. 2023-12-06 2023-12-10 Not clear
Shengjie Feng, Miaoxian Yang, Shengpeng Liu, Yu He, Shuixiang Deng, Ye Gon. Oxidative stress as a bridge between age and stroke: A narrative review. Journal of intensive medicine. vol 3. issue 4. 2023-12-01. PMID:38028635. a rapid increase in the levels of reactive oxygen species (ros) post stroke can overwhelm antioxidant defenses and trigger a series of pathophysiologic events including the inflammatory response, blood-brain barrier (bbb) disruption, apoptosis, and autophagy, ultimately leading to neuron degeneration and apoptosis. 2023-12-01 2023-12-10 Not clear
Tai Zhou, Lei Zhang, Li He, Yan Lan, Lei Ding, Li Li, Zhongcheng Wan. GSK-126 Attenuates Cell Apoptosis in Ischemic Brain Injury by Modulating the EZH2-H3K27me3-Bcl2l1 Axis. Molecular neurobiology. 2023-11-22. PMID:37989985. since the expression of many antiapoptotic genes is inhibited in the ischemic brains, here we aimed to offer an epigenetic solution to cell apoptosis after stroke by reversing h3k27me3 levels after ischemia. 2023-11-22 2023-11-29 Not clear
Victoria Jiménez Carretero, Eva Ramos, Pedro Segura-Chama, Adan Hernández, Andrés M Baraibar, Iris Álvarez-Merz, Francisco López Muñoz, Javier Egea, José M Solís, Alejandro Romero, Jesús M Hernández-Guij. Non-Excitatory Amino Acids, Melatonin, and Free Radicals: Examining the Role in Stroke and Aging. Antioxidants (Basel, Switzerland). vol 12. issue 10. 2023-10-30. PMID:37891922. they can attenuate oxidative stress, modulate calcium homeostasis, and inhibit apoptosis, thereby safeguarding neurons against damage induced by stroke and aging processes. 2023-10-30 2023-11-08 Not clear
Hui Xu, Jiangtao Dong, Yang Li, Lei Zhang, Jiangwen Yin, Chao Zhu, Xu Wang, Kunhao Ren, Hao Zhang, Dong Zha. Neuritin has a neuroprotective role in the rat model of acute ischemia stroke by inhibiting neuronal apoptosis and NLRP3 inflammasome. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 32. issue 12. 2023-10-13. PMID:37832268. neuritin has a neuroprotective role in the rat model of acute ischemia stroke by inhibiting neuronal apoptosis and nlrp3 inflammasome. 2023-10-13 2023-10-15 rat
Hui Xu, Jiangtao Dong, Yang Li, Lei Zhang, Jiangwen Yin, Chao Zhu, Xu Wang, Kunhao Ren, Hao Zhang, Dong Zha. Neuritin has a neuroprotective role in the rat model of acute ischemia stroke by inhibiting neuronal apoptosis and NLRP3 inflammasome. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 32. issue 12. 2023-10-13. PMID:37832268. this study explored the anti-inflammatory, anti-neuronal apoptosis, and neuroprotective effects of neuritin in rat models of acute ischemia stroke (ais). 2023-10-13 2023-10-15 rat
Morgan J Rothschadl, Monica Sathyanesan, Samuel S Newto. Synergism of Carbamoylated Erythropoietin and Insulin-like Growth Factor-1 in Immediate Early Gene Expression. Life (Basel, Switzerland). vol 13. issue 9. 2023-09-28. PMID:37763230. previous preclinical studies have shown synergistic effects on decreasing apoptosis and improving behavioral performance after stroke when combining two such trophic factors, erythropoietin (epo) and insulin-like growth factor-1 (igf-1). 2023-09-28 2023-10-07 rat
Fei Zhuang, Xin Shi, Sen Qiao, Bin Liu, Zhimei Wang, Huanhuan Huo, Feng Liang, Linghong Shen, Lijuan Zhu, Ben He, Hongmei Wan. Allicin promotes functional recovery in ischemic stroke via glutathione peroxidase-1 activation of Src-Akt-Erk. Cell death discovery. vol 9. issue 1. 2023-09-06. PMID:37673878. our results suggested that allicin could significantly ameliorate behavioral characteristics, cerebral infarct area, cell apoptosis, inflammatory factors, and lipid metabolic-related factors (arachidonic acid, 15-hydroperoxy-eicosatetraenoic acid (15s-hpete), palmitoylcarnitine, and acylcarnitine) by recalibrating astrocyte homeostasis in mice with photothrombotic stroke (pt). 2023-09-06 2023-10-07 mouse
Li Wang, Wenzhan Tu, Xuqing Li, Caiyan Li, Junhong Lu, Peng Dai, Yuewei Chen, Meilin Gu, Ming Li, Songhe Jiang, Guanhu Yang, Shengcun L. Exercise improves cardiac function and attenuates myocardial inflammation and apoptosis by regulating APJ/STAT3 in mice with stroke. Life sciences. 2023-09-01. PMID:37657526. exercise improves cardiac function and attenuates myocardial inflammation and apoptosis by regulating apj/stat3 in mice with stroke. 2023-09-01 2023-09-07 mouse
Li Wang, Wenzhan Tu, Xuqing Li, Caiyan Li, Junhong Lu, Peng Dai, Yuewei Chen, Meilin Gu, Ming Li, Songhe Jiang, Guanhu Yang, Shengcun L. Exercise improves cardiac function and attenuates myocardial inflammation and apoptosis by regulating APJ/STAT3 in mice with stroke. Life sciences. 2023-09-01. PMID:37657526. the results demonstrated that chronic exercise prevented myocardial inflammation, apoptosis and cardiac dysfunction after stroke. 2023-09-01 2023-09-07 mouse
Li Wang, Wenzhan Tu, Xuqing Li, Caiyan Li, Junhong Lu, Peng Dai, Yuewei Chen, Meilin Gu, Ming Li, Songhe Jiang, Guanhu Yang, Shengcun L. Exercise improves cardiac function and attenuates myocardial inflammation and apoptosis by regulating APJ/STAT3 in mice with stroke. Life sciences. 2023-09-01. PMID:37657526. this study showed that exercise can maintain apj expression and inhibit p-stat3, thus, conferring protection against myocardial inflammation and apoptosis induced by stroke. 2023-09-01 2023-09-07 mouse
Arshi Waseem, Abdul Quaiyoom Khan, Mohsin Ali Khan, Rehan Khan, Shahab Uddin, Johannes Boltze, Syed Shadab Raz. Unveiling the Therapeutic Potential of Non-coding RNAs in Stroke-Induced Tissue Regeneration. Stem cells (Dayton, Ohio). 2023-08-17. PMID:37591309. aberrant expression of various non-coding rnas (ncrnas) has been identified after stroke onset, impacting neurogenesis, angiogenesis, apoptosis and autophagy. 2023-08-17 2023-09-07 Not clear
Minqi Zhou, Jiayu Xin, Jinyu Chen, Caiyun Sun, Bingyue Huo, Wenting Zhang, Xiangqian Li. Scientific Landscape of Oxidative Stress in Stroke: From a Bibliometric Analysis to an in-Depth Review. Neurochemical research. 2023-07-28. PMID:37505366. current key research areas of os in stroke may lie in the investigation of neuroinflammation, and interaction among multiple cell death mechanisms including apoptosis, autophagy, and ferroptosis to search for effective treatments. 2023-07-28 2023-08-14 Not clear
Binhao Chen, Weifeng Ji. A comprehensive review of stroke-related signaling pathways and treatment in western medicine and traditional Chinese medicine. Frontiers in neuroscience. vol 17. 2023-06-23. PMID:37351420. the involvement of multiple signaling pathways, including sonic hedgehog (shh), nuclear factor erythroid 2-related factor 2 (nrf2)/antioxidant response element (are), hypoxia-inducible factor-1α (hif-1α), pi3k/akt, jak/stat, and ampk in pathophysiological mechanisms such as oxidative stress and apoptosis, highlights the complexity of stroke. 2023-06-23 2023-08-14 Not clear