| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew Mundwiler, Vikram G Shakkotta. Autosomal-dominant cerebellar ataxias. Handbook of clinical neurology. vol 147. 2018-07-26. PMID:29325610. |
spinocerebellar ataxias (scas) are a genetically diverse group of dominantly inherited disorders that share clinical features that result from dysfunction and degeneration of the cerebellum and its associated pathways. |
2018-07-26 |
2023-08-13 |
Not clear |
| Jeanne Hsieh, Jen-Wei Liu, Horng-Jyh Harn, Kuo-Wei Hsueh, Karthyayani Rajamani, Yu-Chen Deng, Chih-Min Chia, Woei-Cheang Shyu, Shinn-Zong Lin, Tzyy-Wen Chio. Human Olfactory Ensheathing Cell Transplantation Improves Motor Function in a Mouse Model of Type 3 Spinocerebellar Ataxia. Cell transplantation. vol 26. issue 10. 2018-07-19. PMID:29251109. |
spinocerebellar ataxia (sca) is a progressive neurodegenerative disease that affects the cerebellum and spinal cord. |
2018-07-19 |
2023-08-13 |
mouse |
| Judit M Pérez Ortiz, Harry T Or. Spinocerebellar Ataxia Type 1: Molecular Mechanisms of Neurodegeneration and Preclinical Studies. Advances in experimental medicine and biology. vol 1049. 2018-07-09. PMID:29427101. |
spinocerebellar ataxia type 1 (sca1) is an adult-onset, inherited disease that leads to degeneration of purkinje cells of the cerebellum and culminates in death 10-30 years after disease onset. |
2018-07-09 |
2023-08-13 |
mouse |
| Xiaofei Du, Christopher Manuel Gome. Spinocerebellar [corrected] Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics. Advances in experimental medicine and biology. vol 1049. 2018-07-09. PMID:29427102. |
spinocerebellar ataxia (sca) type 6 is an autosomal dominant disease affecting cerebellar degeneration. |
2018-07-09 |
2023-08-13 |
Not clear |
| G Olivito, M Lupo, C Iacobacci, S Clausi, S Romano, M Masciullo, M Molinari, M Cercignani, M Bozzali, M Leggi. Microstructural MRI Basis of the Cognitive Functions in Patients with Spinocerebellar Ataxia Type 2. Neuroscience. vol 366. 2018-06-29. PMID:29031602. |
spinocerebellar ataxia type 2 (sca2) is an autosomal dominant neurodegenerative disease involving the cerebellum. |
2018-06-29 |
2023-08-13 |
Not clear |
| Arunmozhi Elavarasi, Deepa Dash, Manjari Tripathi, Rohit Bhati. Cerebellar ataxia and neuropathy as presenting features of hepatitis-B related cirrhosis and portal hypertension. BMJ case reports. vol 2017. 2018-06-14. PMID:29054954. |
adult onset cerebellar dysfunction with neuropathy is a commonly encountered condition and is usually due to genetic causes such as spinocerebellar ataxia, gluten ataxia, alcohol related, toxic, degenerative, immune mediated, paraneoplastic causes and so on. |
2018-06-14 |
2023-08-13 |
Not clear |
| Koji Ab. [An early history of Japanese amyotrophic lateral sclerosis (ALS)-related diseases and the current development]. Rinsho shinkeigaku = Clinical neurology. vol 58. issue 3. 2018-06-07. PMID:29491329. |
in relation to foreign previous reports, five topics are introduced and discussed on als with dementia, als/parkinsonism dementia complex (als/pdc), familial als (fals), spinal bulbar muscular atrophy (sbma), and multisystem involvement especially in cerebellar system of als including als/sca (spinocerebellar ataxia) crossroad mutation asidan. |
2018-06-07 |
2023-08-13 |
Not clear |
| Sriram Jayabal, Hui Ho Vanessa Chang, Kathleen E Cullen, Alanna J Wat. 4-aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6. Scientific reports. vol 6. 2018-06-04. PMID:27381005. |
4-aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6. |
2018-06-04 |
2023-08-13 |
mouse |
| Etsuko Shimobayashi, Josef P Kapfhamme. Increased biological activity of protein Kinase C gamma is not required in Spinocerebellar ataxia 14. Molecular brain. vol 10. issue 1. 2018-05-07. PMID:28738819. |
spinocerebellar ataxia (sca) is an autosomal dominant neurodegenerative disorder characterized by slowly progressive cerebellar dysfunction. |
2018-05-07 |
2023-08-13 |
Not clear |
| Wenhui Qu, Andrea Johnson, Joo Hyun Kim, Abigail Lukowicz, Daniel Svedberg, Marija Cvetanovi. Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice. Journal of neuroinflammation. vol 14. issue 1. 2018-03-26. PMID:28545543. |
polyglutamine (polyq) expansion in the protein ataxin-1 (atxn1) causes spinocerebellar ataxia type 1 (sca1), a fatal dominantly inherited neurodegenerative disease characterized by motor deficits, cerebellar neurodegeneration, and gliosis. |
2018-03-26 |
2023-08-13 |
mouse |
| Chiharu Isono, Makito Hirano, Hikaru Sakamoto, Shuichi Ueno, Susumu Kusunoki, Yusaku Nakamur. Progression of Dysphagia in Spinocerebellar Ataxia Type 6. Dysphagia. vol 32. issue 3. 2018-03-12. PMID:28042641. |
spinocerebellar ataxia type 6 (sca6), an autosomal dominant triplet repeat disease, predominantly affects the cerebellum with a late onset and generally good prognosis. |
2018-03-12 |
2023-08-13 |
Not clear |
| Luis Velázquez-Pérez, Roberto Rodríguez-Labrada, José Miguel Laffita-Mes. Prodromal spinocerebellar ataxia type 2: Prospects for early interventions and ethical challenges. Movement disorders : official journal of the Movement Disorder Society. vol 32. issue 5. 2018-02-06. PMID:28256108. |
research during the past 3 decades in spinocerebellar ataxia type 2 has revealed a large body of evidence suggesting that many disease features precede the manifest cerebellar syndrome, which delineates the prodromal stage of this disorder. |
2018-02-06 |
2023-08-13 |
Not clear |
| Lulin Choubtum, Pirada Witoonpanich, Kongkiat Kulkantrakorn, Suchat Hanchaiphiboolkul, Sunsanee Pongpakdee, Somsak Tiamkao, Teeratorn Pulke. Trinucleotide repeat expansion of TATA-binding protein gene associated with Parkinson's disease: A Thai multicenter study. Parkinsonism & related disorders. vol 28. 2018-02-05. PMID:27172828. |
spinocerebellar ataxia type 17 (sca17) is an inherited cerebellar degeneration associated with trinucleotide repeat expansions in the tata-binding protein gene (tbp). |
2018-02-05 |
2023-08-13 |
Not clear |
| Austin Ferro, Emily Carbone, Evan Marzouk, Asher Siegel, Donna Nguyen, Kailen Polley, Jessilyn Hartman, Kimberley Frederick, Stephen Ives, Sarita Lagalwa. Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function. Journal of visualized experiments : JoVE. issue 119. 2018-01-29. PMID:28190022. |
mitochondrial dysfunction plays a significant role in the aging process and in neurodegenerative diseases including several hereditary spinocerebellar ataxias and other movement disorders marked by progressive degeneration of the cerebellum. |
2018-01-29 |
2023-08-13 |
mouse |
| U Rüb, K Seidel, H Heinsen, J P Vonsattel, W F den Dunnen, H W Kor. Huntington's disease (HD): the neuropathology of a multisystem neurodegenerative disorder of the human brain. Brain pathology (Zurich, Switzerland). vol 26. issue 6. 2018-01-17. PMID:27529157. |
the multisystem character of the neuropathology of hd is emphasized by a brain distribution pattern of neurodegeneration (i) which apart from the striatum includes the cerebral neo-and allocortex, thalamus, pallidum, brainstem and cerebellum, and which (ii) therefore, shares more similarities with polyglutamine spinocerebellar ataxias than previously thought. |
2018-01-17 |
2023-08-13 |
human |
| M I Falcon, C M Gomez, E E Chen, A Shereen, A Solodki. Early Cerebellar Network Shifting in Spinocerebellar Ataxia Type 6. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 7. 2018-01-15. PMID:26209844. |
early cerebellar network shifting in spinocerebellar ataxia type 6. |
2018-01-15 |
2023-08-13 |
Not clear |
| Austin Ferro, Emily Carbone, Jenny Zhang, Evan Marzouk, Monica Villegas, Asher Siegel, Donna Nguyen, Thomas Possidente, Jessilyn Hartman, Kailen Polley, Melissa A Ingram, Georgia Berry, Thomas H Reynolds, Bernard Possidente, Kimberley Frederick, Stephen Ives, Sarita Lagalwa. Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model. PloS one. vol 12. issue 12. 2017-12-29. PMID:29211771. |
short-term succinic acid treatment mitigates cerebellar mitochondrial oxphos dysfunction, neurodegeneration and ataxia in a purkinje-specific spinocerebellar ataxia type 1 (sca1) mouse model. |
2017-12-29 |
2023-08-13 |
mouse |
| Austin Ferro, Emily Carbone, Jenny Zhang, Evan Marzouk, Monica Villegas, Asher Siegel, Donna Nguyen, Thomas Possidente, Jessilyn Hartman, Kailen Polley, Melissa A Ingram, Georgia Berry, Thomas H Reynolds, Bernard Possidente, Kimberley Frederick, Stephen Ives, Sarita Lagalwa. Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model. PloS one. vol 12. issue 12. 2017-12-29. PMID:29211771. |
in this study, we investigate the role of mitochondrial oxidative phosphorylation (oxphos) deficits in cerebellar tissue of a purkinje cell-driven spinocerebellar ataxia type 1 (sca1) mouse. |
2017-12-29 |
2023-08-13 |
mouse |
| Yoshihito Ishida, Hideshi Kawakami, Hiroyuki Kitajima, Ayaka Nishiyama, Yoshiki Sasai, Haruhisa Inoue, Keiko Mugurum. Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs. Cell reports. vol 17. issue 6. 2017-11-20. PMID:27806289. |
spinocerebellar ataxia type 6 (sca6) is a dominantly inherited neurodegenerative disease characterized by loss of purkinje cells in the cerebellum. |
2017-11-20 |
2023-08-13 |
Not clear |
| Shang-Ran Huang, Yu-Te Wu, Chii-Wen Jao, Bing-Wen Soong, Jiing-Feng Lirng, Hsiu-Mei Wu, Po-Shan Wan. CAG repeat length does not associate with the rate of cerebellar degeneration in spinocerebellar ataxia type 3. NeuroImage. Clinical. vol 13. 2017-11-17. PMID:27942452. |
cag repeat length does not associate with the rate of cerebellar degeneration in spinocerebellar ataxia type 3. |
2017-11-17 |
2023-08-13 |
Not clear |