| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kazunori Nanri, Nobuaki Yoshikura, Akio Kimura, Sayaka Nakayama, Takayuki Otomo, Takayoshi Shimohata, Hiroo Terashi, Tatsuya Sato, Junji Yamad. [Cerebellar Ataxia and Autoantibodies]. Brain and nerve = Shinkei kenkyu no shinpo. vol 70. issue 4. 2019-05-10. PMID:29632285. |
magnetic resonance imaging voxel-based morphometry is also useful because it can detect cortical cerebellar atrophy of autoimmune cerebellar ataxia, different from spinocerebellar ataxia. |
2019-05-10 |
2023-08-13 |
Not clear |
| Yu-Ling Wu, Jui-Chih Chang, Wei-Yong Lin, Chien-Chun Li, Mingli Hsieh, Haw-Wen Chen, Tsu-Shing Wang, Wen-Tzu Wu, Chin-San Liu, Kai-Li Li. Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway. Free radical biology & medicine. vol 115. 2019-05-03. PMID:29247688. |
polyglutamine (polyq)-expanded mutant ataxin-3 protein, which is prone to misfolding and aggregation, leads to cerebellar neurotoxicity in spinocerebellar ataxia type 3 (sca3), an inherited polyq neurodegenerative disease. |
2019-05-03 |
2023-08-13 |
drosophila_melanogaster |
| Terri M Driessen, Paul J Lee, Janghoo Li. Molecular pathway analysis towards understanding tissue vulnerability in spinocerebellar ataxia type 1. eLife. vol 7. 2019-03-28. PMID:30507379. |
the neurodegenerative disorder spinocerebellar ataxia type 1 (sca1) affects the cerebellum and inferior olive, though previous research has focused primarily on the cerebellum. |
2019-03-28 |
2023-08-13 |
mouse |
| Hirokazu Hirai, Masanobu Kan. Type 1 metabotropic glutamate receptor and its signaling molecules as therapeutic targets for the treatment of cerebellar disorders. Current opinion in pharmacology. vol 38. 2019-03-14. PMID:29525719. |
neurodegenerative diseases such as spinocerebellar ataxias and autoantibody-associated disorders of the central nervous system often affect the cerebellum, resulting in motor deficits. |
2019-03-14 |
2023-08-13 |
Not clear |
| Emily Bowie, Ryan Norris, Kathryn V Anderson, Sarah C Goet. Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability. PLoS genetics. vol 14. issue 12. 2019-03-04. PMID:30532139. |
spinocerebellar ataxia type 11 (sca11) is a rare, dominantly inherited human ataxia characterized by atrophy of purkinje neurons in the cerebellum. |
2019-03-04 |
2023-08-13 |
human |
| Elan D Louis, Sheng-Han Kuo, William J Tate, Geoffrey C Kelly, Jesus Gutierrez, Etty P Cortes, Jean-Paul G Vonsattel, Phyllis L Faus. Heterotopic Purkinje Cells: a Comparative Postmortem Study of Essential Tremor and Spinocerebellar Ataxias 1, 2, 3, and 6. Cerebellum (London, England). vol 17. issue 2. 2019-02-28. PMID:28791574. |
we (1) quantify heterotopias in et cases vs. controls, (2) compare et cases to other cerebellar degenerative conditions (spinocerebellar ataxias (scas) 1, 2, 3, and 6), (3) compare these scas to one another, and (4) assess heterotopia within the context of associated pc loss in each disease. |
2019-02-28 |
2023-08-13 |
Not clear |
| Akiyoshi Matsugi, Yutaka Kikuchi, Kenta Kaneko, Yuta Seko, Masato Odagak. Cerebellar transcranial magnetic stimulation facilitates excitability of spinal reflex, but does not affect cerebellar inhibition and facilitation in spinocerebellar ataxia. Neuroreport. vol 29. issue 10. 2019-02-27. PMID:29659444. |
cerebellar transcranial magnetic stimulation facilitates excitability of spinal reflex, but does not affect cerebellar inhibition and facilitation in spinocerebellar ataxia. |
2019-02-27 |
2023-08-13 |
Not clear |
| Akiyoshi Matsugi, Yutaka Kikuchi, Kenta Kaneko, Yuta Seko, Masato Odagak. Cerebellar transcranial magnetic stimulation facilitates excitability of spinal reflex, but does not affect cerebellar inhibition and facilitation in spinocerebellar ataxia. Neuroreport. vol 29. issue 10. 2019-02-27. PMID:29659444. |
the aim of this study was to investigate whether such cerebellar spinal facilitation (cspf) appears in patients with spinocerebellar ataxia (sca) presenting with atrophy in the cerebellar gray matter and dentate nucleus. |
2019-02-27 |
2023-08-13 |
Not clear |
| Miaozhen Huang, Dineke S Verbee. Why do so many genetic insults lead to Purkinje Cell degeneration and spinocerebellar ataxia? Neuroscience letters. vol 688. 2019-02-18. PMID:29421540. |
the genetically heterozygous spinocerebellar ataxias are all characterized by cerebellar atrophy and pervasive purkinje cell degeneration. |
2019-02-18 |
2023-08-13 |
Not clear |
| Carlos R Hernandez-Castillo, Maedbh King, Jörn Diedrichsen, Juan Fernandez-Rui. Unique degeneration signatures in the cerebellar cortex for spinocerebellar ataxias 2, 3, and 7. NeuroImage. Clinical. vol 20. 2019-02-05. PMID:30308379. |
spinocerebellar ataxias (scas) are a heterogeneous group of neurodegenerative diseases that selectively affect vulnerable neuronal populations in the cerebellum and other subcortical regions. |
2019-02-05 |
2023-08-13 |
Not clear |
| Austin Ferro, Wenhui Qu, Abigail Lukowicz, Daniel Svedberg, Andrea Johnson, Marija Cvetanovi. Inhibition of NF-κB signaling in IKKβF/F;LysM Cre mice causes motor deficits but does not alter pathogenesis of Spinocerebellar ataxia type 1. PloS one. vol 13. issue 7. 2019-01-01. PMID:29975753. |
spinocerebellar ataxia type 1 (sca1) is a fatal neurodegenerative genetic disease that is characterized by pronounced neuronal loss and gliosis in the cerebellum. |
2019-01-01 |
2023-08-13 |
mouse |
| Ming Li, Qianqian Ma, Xing Zhao, Can Wang, Huijie Wu, Jinyao Li, Wei Yan. Dilemma of multiple system atrophy and spinocerebellar ataxias. Journal of neurology. vol 265. issue 12. 2018-12-27. PMID:29700645. |
multiple system atrophy (msa) and spinocerebellar ataxias (scas) are both progressive neurodegenerative disorders, which can manifest cerebellar dysfunctions and parkinsonism-related symptoms, although the former is sporadic and the latter is autosomal dominant disease. |
2018-12-27 |
2023-08-13 |
Not clear |
| Carlos Roberto Martins Junior, Alberto Rolim Muro Martinez, Ingrid Faber Vasconcelos, Thiago Junqueira Ribeiro de Rezende, Raphael Fernandes Casseb, Jose Luiz Pedroso, Orlando Graziani Povoas Barsottini, Íscia Lopes-Cendes, Marcondes Cavalcante Franç. Structural signature in SCA1: clinical correlates, determinants and natural history. Journal of neurology. vol 265. issue 12. 2018-12-27. PMID:30324307. |
spinocerebellar ataxia type 1 is an autosomal dominant disorder caused by a cag repeat expansion in atxn1, characterized by progressive cerebellar and extracerebellar symptoms. |
2018-12-27 |
2023-08-13 |
Not clear |
| Hiroyuki Yahikozawa, Satoko Miyatake, Toshiaki Sakai, Takeshi Uehara, Mitsunori Yamada, Norinao Hanyu, Yasuhiro Futatsugi, Hiroshi Doi, Shigeru Koyano, Fumiaki Tanaka, Atsushi Suzuki, Naomichi Matsumoto, Kunihiro Yoshid. A Japanese Family of Spinocerebellar Ataxia Type 21: Clinical and Neuropathological Studies. Cerebellum (London, England). vol 17. issue 5. 2018-11-06. PMID:29687291. |
spinocerebellar ataxia type 21 (sca21) is a rare subtype of autosomal dominant cerebellar ataxias, which was first identified in a french family and has been reported almost exclusively in french ancestry so far. |
2018-11-06 |
2023-08-13 |
Not clear |
| Stefania Squadrone, Paola Brizio, Cecilia Mancini, Maria Cesarina Abete, Alfredo Brusc. Altered homeostasis of trace elements in the blood of SCA2 patients. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 47. 2018-10-05. PMID:29544796. |
spinocerebellar ataxia type 2 (sca2) is a neurological disorder characterized by cerebellar dysfunction. |
2018-10-05 |
2023-08-13 |
Not clear |
| Carlo Wilke, Friedemann Bender, Stefanie N Hayer, Kathrin Brockmann, Ludger Schöls, Jens Kuhle, Matthis Synofzi. Serum neurofilament light is increased in multiple system atrophy of cerebellar type and in repeat-expansion spinocerebellar ataxias: a pilot study. Journal of neurology. vol 265. issue 7. 2018-10-04. PMID:29737427. |
serum neurofilament light is increased in multiple system atrophy of cerebellar type and in repeat-expansion spinocerebellar ataxias: a pilot study. |
2018-10-04 |
2023-08-13 |
human |
| Carlo Wilke, Friedemann Bender, Stefanie N Hayer, Kathrin Brockmann, Ludger Schöls, Jens Kuhle, Matthis Synofzi. Serum neurofilament light is increased in multiple system atrophy of cerebellar type and in repeat-expansion spinocerebellar ataxias: a pilot study. Journal of neurology. vol 265. issue 7. 2018-10-04. PMID:29737427. |
specifically, as a marker of neuronal damage, nfl might (1) help to differentiate multiple system atrophy of cerebellar type (msa-c) from sporadic adult-onset ataxia (saoa), and (2) show increases in repeat-expansion spinocerebellar ataxias (scas) which might be amenable to treatment in the future. |
2018-10-04 |
2023-08-13 |
human |
| Etsuko Shimobayashi, Josef P Kapfhamme. Calcium Signaling, PKC Gamma, IP3R1 and CAR8 Link Spinocerebellar Ataxias and Purkinje Cell Dendritic Development. Current neuropharmacology. vol 16. issue 2. 2018-10-01. PMID:28554312. |
spinocerebellar ataxias (scas) are a group of cerebellar diseases characterized by progressive ataxia and cerebellar atrophy. |
2018-10-01 |
2023-08-13 |
Not clear |
| James P Orengo, Meike E van der Heijden, Shuang Hao, Jianrong Tang, Harry T Orr, Huda Y Zoghb. Motor neuron degeneration correlates with respiratory dysfunction in SCA1. Disease models & mechanisms. vol 11. issue 2. 2018-10-01. PMID:29419414. |
spinocerebellar ataxia type 1 (sca1) is characterized by adult-onset cerebellar degeneration with attendant loss of motor coordination. |
2018-10-01 |
2023-08-13 |
Not clear |
| Arnulf H Koeppe. The neuropathology of the adult cerebellum. Handbook of clinical neurology. vol 154. 2018-09-28. PMID:29903436. |
the cerebellum is a prominent target of several sporadic and hereditary neurodegenerative diseases, including multiple system atrophy, spinocerebellar ataxia, and friedreich ataxia. |
2018-09-28 |
2023-08-13 |
Not clear |