| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nura Hamidu Alkali, Sunday A Bwala, Saeed A Alimi, Shyngle I Oyakhir. Spinocerebellar ataxia type-7: Report of a family in Northwest Nigeria. Annals of African medicine. vol 15. issue 2. 2016-09-16. PMID:27044733. |
spinocerebellar ataxia type-7 (sca7) is a cytosine-adenine-guanine (cag) repeat polyglutamine disorder characterized by progressive degeneration of the cerebellum, brainstem, spinal cord, and retina. |
2016-09-16 |
2023-08-13 |
Not clear |
| Chiharu Isono, Makito Hirano, Hikaru Sakamoto, Shuichi Ueno, Susumu Kusunoki, Yusaku Nakamur. Differential Progression of Dysphagia in Heredity and Sporadic Ataxias Involving Multiple Systems. European neurology. vol 74. issue 5-6. 2016-08-29. PMID:26618669. |
sporadic ataxia affecting multiple systems, such as cerebellar, extrapyramidal, and autonomic systems, is known as multiple system atrophy cerebellar type (msa-c), while similar multisystem involvements are seen in certain types of hereditary ataxia, such as spinocerebellar ataxia type 3 (sca3). |
2016-08-29 |
2023-08-13 |
Not clear |
| Lena Constantin, Brandon J Wainwrigh. MicroRNAs Promote Granule Cell Expansion in the Cerebellum Through Gli2. Cerebellum (London, England). vol 14. issue 6. 2016-08-15. PMID:25910616. |
their deregulation results in cerebellar neuronal degeneration and spinocerebellar ataxia type 1 and contributes to medulloblastoma. |
2016-08-15 |
2023-08-13 |
mouse |
| Sarah Doss, Jan Leo Rinnenthal, Tanja Schmitz-Hübsch, Alexander U Brandt, Sebastian Papazoglou, Silke Lux, Stephan Maul, Jens Würfel, Matthias Endres, Thomas Klockgether, Martina Minnerop, Friedemann Pau. Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency. Journal of neurology. vol 262. issue 8. 2016-06-22. PMID:26041613. |
cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency. |
2016-06-22 |
2023-08-13 |
Not clear |
| Carlos R Hernandez-Castillo, Víctor Galvez, Roberto E Mercadillo, Rosalinda Díaz, Petra Yescas, Leticia Martinez, Adriana Ochoa, Luis Velazquez-Perez, Juan Fernandez-Rui. Functional connectivity changes related to cognitive and motor performance in spinocerebellar ataxia type 2. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 10. 2016-06-17. PMID:26256273. |
several neuropathological studies in spinocerebellar ataxia type 2 (sca2) have revealed significant atrophy of the cerebellum, brainstem, sensorimotor cortex, and several regions in the frontal lobe. |
2016-06-17 |
2023-08-13 |
Not clear |
| Megan S Keiser, Jeffrey H Kordower, Pedro Gonzalez-Alegre, Beverly L Davidso. Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy. Brain : a journal of neurology. vol 138. issue Pt 12. 2016-05-04. PMID:26490326. |
spinocerebellar ataxia type 1 is one of nine polyglutamine expansion diseases and is characterized by cerebellar ataxia and neuronal degeneration in the cerebellum and brainstem. |
2016-05-04 |
2023-08-13 |
mouse |
| Megan S Keiser, Jeffrey H Kordower, Pedro Gonzalez-Alegre, Beverly L Davidso. Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy. Brain : a journal of neurology. vol 138. issue Pt 12. 2016-05-04. PMID:26490326. |
collectively the data illustrate the biodistribution and tolerability of raav1.mis1egfp administration to the adult rhesus cerebellum and are supportive of clinical application for spinocerebellar ataxia type 1. |
2016-05-04 |
2023-08-13 |
mouse |
| Jian-Wen Chen, Li Zhao, Feng Zhang, Lan Li, Yu-Hang Gu, Jing-Yuan Zhou, Hui Zhang, Ming Meng, Kai-Hua Zhang, Wei-Dong Le, Chun-Bo Don. Clinical Characteristics, Radiological Features and Gene Mutation in 10 Chinese Families with Spinocerebellar Ataxias. Chinese medical journal. vol 128. issue 13. 2016-03-15. PMID:26112709. |
spinocerebellar ataxias (scas) are a group of neurodegenerative disorders that primarily cause the degeneration in the cerebellum, spinal cord, and brainstem. |
2016-03-15 |
2023-08-13 |
Not clear |
| Irene Pulido-Valdeolivas, David Gómez-Andrés, Irene Sanz-Gallego, Estrella Rausell, Javier Arp. Patterns of motor signs in spinocerebellar ataxia type 3 at the start of follow-up in a reference unit. Cerebellum & ataxias. vol 3. 2016-02-24. PMID:26909158. |
spinocerebellar ataxia type 3 (sca3) is a neurodegenerative disorder that affects the cerebellar system and other subcortical regions of the brain. |
2016-02-24 |
2023-08-13 |
Not clear |
| David D Bushart, Geoffrey G Murphy, Vikram G Shakkotta. Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease. Annals of translational medicine. vol 4. issue 2. 2016-02-18. PMID:26889478. |
spinocerebellar ataxias (scas) are a heterogeneous group of dominantly inherited neurodegenerative disorders affecting the cerebellum and its associated pathways. |
2016-02-18 |
2023-08-13 |
Not clear |
| Xuejing Wang, Hui Wang, Yujun Xia, Hong Jiang, Lu Shen, Shoubiao Wang, Ruowu Shen, Qian Xu, Xuegang Luo, Beisha Tan. Spinocerebellar ataxia type 6: Systematic patho-anatomical study reveals different phylogenetically defined regions of the cerebellum and neural pathways undergo different evolutions of the degenerative process. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 30. issue 5. 2016-02-17. PMID:20113406. |
spinocerebellar ataxia type 6: systematic patho-anatomical study reveals different phylogenetically defined regions of the cerebellum and neural pathways undergo different evolutions of the degenerative process. |
2016-02-17 |
2023-08-12 |
Not clear |
| Ludger Schöls, Matthias Reimold, Kay Seidel, Christoph Globas, Kathrin Brockmann, Till Karsten Hauser, Georg Auburger, Katrin Bürk, Wilfred den Dunnen, Gerald Reischl, Horst-Werner Korf, Ewout R Brunt, Udo Rü. No parkinsonism in SCA2 and SCA3 despite severe neurodegeneration of the dopaminergic substantia nigra. Brain : a journal of neurology. vol 138. issue Pt 11. 2016-02-09. PMID:26362908. |
see klockgether (doi:10.1093/awv253) for a scientific commentary on this article.the spinocerebellar ataxias types 2 (sca2) and 3 (sca3) are autosomal dominantly inherited cerebellar ataxias which are caused by cag trinucleotide repeat expansions in the coding regions of the disease-specific genes. |
2016-02-09 |
2023-08-13 |
Not clear |
| K Sato, K Ishigame, S H Ying, K Oishi, M I Miller, S Mor. Macro- and microstructural changes in patients with spinocerebellar ataxia type 6: assessment of phylogenetic subdivisions of the cerebellum and the brain stem. AJNR. American journal of neuroradiology. vol 36. issue 1. 2016-01-14. PMID:25169926. |
macro- and microstructural changes in patients with spinocerebellar ataxia type 6: assessment of phylogenetic subdivisions of the cerebellum and the brain stem. |
2016-01-14 |
2023-08-13 |
Not clear |
| Anna Duarri, Esther A R Nibbeling, Michiel R Fokkens, Michel Meijer, Melissa Boerrigter, Corien C Verschuuren-Bemelmans, Berry P H Kremer, Bart P van de Warrenburg, Dennis Dooijes, Erik Boddeke, Richard J Sinke, Dineke S Verbee. Functional analysis helps to define KCNC3 mutational spectrum in Dutch ataxia cases. PloS one. vol 10. issue 3. 2016-01-13. PMID:25756792. |
spinocerebellar ataxia type 13 (sca13) is an autosomal dominantly inherited neurodegenerative disorder of the cerebellum caused by mutations in the voltage gated potassium channel kcnc3. |
2016-01-13 |
2023-08-13 |
Not clear |
| Yi Dong, Jian-Jun Wu, Zhi-Ying W. Identification of 46 CAG repeats within PPP2R2B as probably the shortest pathogenic allele for SCA12. Parkinsonism & related disorders. vol 21. issue 4. 2016-01-11. PMID:25634432. |
spinocerebellar ataxia type 12 (sca12) is predominantly characterized by action tremor, followed by slowly progressive cerebellar dysfunction. |
2016-01-11 |
2023-08-13 |
Not clear |
| Isaac M Adanyeguh, Pierre-Gilles Henry, Tra M Nguyen, Daisy Rinaldi, Celine Jauffret, Romain Valabregue, Uzay E Emir, Dinesh K Deelchand, Alexis Brice, Lynn E Eberly, Gülin Öz, Alexandra Durr, Fanny Moche. In vivo neurometabolic profiling in patients with spinocerebellar ataxia types 1, 2, 3, and 7. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 5. 2015-12-29. PMID:25773989. |
spinocerebellar ataxias (scas) belong to polyglutamine repeat disorders and are characterized by a predominant atrophy of the cerebellum and the pons. |
2015-12-29 |
2023-08-13 |
Not clear |
| Yukari H Takeo, Wataru Kakegawa, Eriko Miura, Michisuke Yuzak. RORα Regulates Multiple Aspects of Dendrite Development in Cerebellar Purkinje Cells In Vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 36. 2015-12-14. PMID:26354918. |
because rorα deficiency during development is closely related to the severity of spinocerebellar ataxia type 1, delineating the specific roles of rorα in pcs in vivo at different time windows during development and throughout adulthood would facilitate our understanding of the pathogenesis of cerebellar disorders. |
2015-12-14 |
2023-08-13 |
mouse |
| Shunichi Matsuda, Hideyuki Matsumoto, Toshiaki Furubayashi, Ritsuko Hanajima, Shoji Tsuji, Yoshikazu Ugawa, Yasuo Tera. The 3-second rule in hereditary pure cerebellar ataxia: a synchronized tapping study. PloS one. vol 10. issue 2. 2015-12-03. PMID:25706752. |
the aim of paper was to investigate the temporal processing in patients with spinocerebellar ataxia type 6 (sca6) and sca31, pure cerebellar types of spinocerebellar degeneration, using a synchronized tapping task. |
2015-12-03 |
2023-08-13 |
human |
| Shunichi Matsuda, Hideyuki Matsumoto, Toshiaki Furubayashi, Hideki Fukuda, Ritsuko Hanajima, Shoji Tsuji, Yoshikazu Ugawa, Yasuo Tera. Visual scanning area is abnormally enlarged in hereditary pure cerebellar ataxia. Cerebellum (London, England). vol 14. issue 2. 2015-12-01. PMID:25231433. |
the aim of paper was to investigate abnormalities in visual scanning using an eye-tracking device with patients with spinocerebellar ataxia type 6 (sca6) and sca31, pure cerebellar types of spinocerebellar degeneration. |
2015-12-01 |
2023-08-13 |
human |
| M Cvetanovic, M Ingram, H Orr, P Opa. Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1. Neuroscience. vol 289. 2015-12-01. PMID:25595967. |
spinocerebellar ataxia type 1 (sca1) is an incurable, dominantly inherited neurodegenerative disease of the cerebellum caused by a polyglutamine-repeat expansion in the protein ataxin-1 (atxn1). |
2015-12-01 |
2023-08-13 |
mouse |