| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xuejing Wang, Hui Wang, Yujun Xia, Hong Jiang, Lu Shen, Shoubiao Wang, Ruowu Shen, Qian Xu, Xuegang Luo, Beisha Tan. Spinocerebellar ataxia type 6: Systematic patho-anatomical study reveals different phylogenetically defined regions of the cerebellum and neural pathways undergo different evolutions of the degenerative process. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 30. issue 5. 2016-02-17. PMID:20113406. |
spinocerebellar ataxia type 6: systematic patho-anatomical study reveals different phylogenetically defined regions of the cerebellum and neural pathways undergo different evolutions of the degenerative process. |
2016-02-17 |
2023-08-12 |
Not clear |
| Ludger Schöls, Matthias Reimold, Kay Seidel, Christoph Globas, Kathrin Brockmann, Till Karsten Hauser, Georg Auburger, Katrin Bürk, Wilfred den Dunnen, Gerald Reischl, Horst-Werner Korf, Ewout R Brunt, Udo Rü. No parkinsonism in SCA2 and SCA3 despite severe neurodegeneration of the dopaminergic substantia nigra. Brain : a journal of neurology. vol 138. issue Pt 11. 2016-02-09. PMID:26362908. |
see klockgether (doi:10.1093/awv253) for a scientific commentary on this article.the spinocerebellar ataxias types 2 (sca2) and 3 (sca3) are autosomal dominantly inherited cerebellar ataxias which are caused by cag trinucleotide repeat expansions in the coding regions of the disease-specific genes. |
2016-02-09 |
2023-08-13 |
Not clear |
| K Sato, K Ishigame, S H Ying, K Oishi, M I Miller, S Mor. Macro- and microstructural changes in patients with spinocerebellar ataxia type 6: assessment of phylogenetic subdivisions of the cerebellum and the brain stem. AJNR. American journal of neuroradiology. vol 36. issue 1. 2016-01-14. PMID:25169926. |
macro- and microstructural changes in patients with spinocerebellar ataxia type 6: assessment of phylogenetic subdivisions of the cerebellum and the brain stem. |
2016-01-14 |
2023-08-13 |
Not clear |
| Anna Duarri, Esther A R Nibbeling, Michiel R Fokkens, Michel Meijer, Melissa Boerrigter, Corien C Verschuuren-Bemelmans, Berry P H Kremer, Bart P van de Warrenburg, Dennis Dooijes, Erik Boddeke, Richard J Sinke, Dineke S Verbee. Functional analysis helps to define KCNC3 mutational spectrum in Dutch ataxia cases. PloS one. vol 10. issue 3. 2016-01-13. PMID:25756792. |
spinocerebellar ataxia type 13 (sca13) is an autosomal dominantly inherited neurodegenerative disorder of the cerebellum caused by mutations in the voltage gated potassium channel kcnc3. |
2016-01-13 |
2023-08-13 |
Not clear |
| Yi Dong, Jian-Jun Wu, Zhi-Ying W. Identification of 46 CAG repeats within PPP2R2B as probably the shortest pathogenic allele for SCA12. Parkinsonism & related disorders. vol 21. issue 4. 2016-01-11. PMID:25634432. |
spinocerebellar ataxia type 12 (sca12) is predominantly characterized by action tremor, followed by slowly progressive cerebellar dysfunction. |
2016-01-11 |
2023-08-13 |
Not clear |
| Isaac M Adanyeguh, Pierre-Gilles Henry, Tra M Nguyen, Daisy Rinaldi, Celine Jauffret, Romain Valabregue, Uzay E Emir, Dinesh K Deelchand, Alexis Brice, Lynn E Eberly, Gülin Öz, Alexandra Durr, Fanny Moche. In vivo neurometabolic profiling in patients with spinocerebellar ataxia types 1, 2, 3, and 7. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 5. 2015-12-29. PMID:25773989. |
spinocerebellar ataxias (scas) belong to polyglutamine repeat disorders and are characterized by a predominant atrophy of the cerebellum and the pons. |
2015-12-29 |
2023-08-13 |
Not clear |
| Yukari H Takeo, Wataru Kakegawa, Eriko Miura, Michisuke Yuzak. RORα Regulates Multiple Aspects of Dendrite Development in Cerebellar Purkinje Cells In Vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 36. 2015-12-14. PMID:26354918. |
because rorα deficiency during development is closely related to the severity of spinocerebellar ataxia type 1, delineating the specific roles of rorα in pcs in vivo at different time windows during development and throughout adulthood would facilitate our understanding of the pathogenesis of cerebellar disorders. |
2015-12-14 |
2023-08-13 |
mouse |
| Shunichi Matsuda, Hideyuki Matsumoto, Toshiaki Furubayashi, Ritsuko Hanajima, Shoji Tsuji, Yoshikazu Ugawa, Yasuo Tera. The 3-second rule in hereditary pure cerebellar ataxia: a synchronized tapping study. PloS one. vol 10. issue 2. 2015-12-03. PMID:25706752. |
the aim of paper was to investigate the temporal processing in patients with spinocerebellar ataxia type 6 (sca6) and sca31, pure cerebellar types of spinocerebellar degeneration, using a synchronized tapping task. |
2015-12-03 |
2023-08-13 |
human |
| Shunichi Matsuda, Hideyuki Matsumoto, Toshiaki Furubayashi, Hideki Fukuda, Ritsuko Hanajima, Shoji Tsuji, Yoshikazu Ugawa, Yasuo Tera. Visual scanning area is abnormally enlarged in hereditary pure cerebellar ataxia. Cerebellum (London, England). vol 14. issue 2. 2015-12-01. PMID:25231433. |
the aim of paper was to investigate abnormalities in visual scanning using an eye-tracking device with patients with spinocerebellar ataxia type 6 (sca6) and sca31, pure cerebellar types of spinocerebellar degeneration. |
2015-12-01 |
2023-08-13 |
human |
| M Cvetanovic, M Ingram, H Orr, P Opa. Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1. Neuroscience. vol 289. 2015-12-01. PMID:25595967. |
spinocerebellar ataxia type 1 (sca1) is an incurable, dominantly inherited neurodegenerative disease of the cerebellum caused by a polyglutamine-repeat expansion in the protein ataxin-1 (atxn1). |
2015-12-01 |
2023-08-13 |
mouse |
| Ho Tsoi, Allen C S Yu, Zhefan S Chen, Nelson K N Ng, Anne Y Y Chan, Liz Y P Yuen, Jill M Abrigo, Suk Ying Tsang, Stephen K W Tsui, Tony M F Tong, Ivan F M Lo, Stephen T S Lam, Vincent C T Mok, Lawrence K S Wong, Jacky C K Ngo, Kwok-Fai Lau, Ting-Fung Chan, H Y Edwin Cha. A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia. Journal of medical genetics. vol 51. issue 9. 2015-11-05. PMID:25062847. |
spinocerebellar ataxias (scas) are a group of clinically and genetically diverse and autosomal-dominant disorders characterised by neurological deficits in the cerebellum. |
2015-11-05 |
2023-08-13 |
Not clear |
| T J R de Rezende, A D'Abreu, R P Guimarães, T M Lopes, I Lopes-Cendes, F Cendes, G Castellano, M C Franç. Cerebral cortex involvement in Machado-Joseph disease. European journal of neurology. vol 22. issue 2. 2015-11-03. PMID:25251537. |
machado-joseph disease (mjd/sca3) is the most frequent spinocerebellar ataxia, characterized by brainstem, basal ganglia and cerebellar damage. |
2015-11-03 |
2023-08-13 |
Not clear |
| Marija Cvetanovi. Decreased expression of glutamate transporter GLAST in Bergmann glia is associated with the loss of Purkinje neurons in the spinocerebellar ataxia type 1. Cerebellum (London, England). vol 14. issue 1. 2015-10-23. PMID:25255716. |
spinocerebellar ataxia type 1 (sca1) is a dominantly inherited neurodegenerative disease of the cerebellum caused by a polyglutamine-repeat expansion in the protein atxn1. |
2015-10-23 |
2023-08-13 |
mouse |
| Tao Hu, Bi Zhao, Qian-qian Wei, Huifang Shan. Unusual cerebral white matter change in a Chinese family with Spinocerebellar ataxia type 12. Journal of the neurological sciences. vol 349. issue 1-2. 2015-09-28. PMID:25586539. |
in a chinese family with spinocerebellar ataxia type 12 (sca12), presenting with action tremor, mild cerebellar dysfunction, and hyperreflexia, genetic testing revealed abnormal cag repeat length in the brain-specific protein phosphatase 2, regulatory subunit b, beta isoform (ppp2r2b) gene. |
2015-09-28 |
2023-08-13 |
Not clear |
| Roderick P P W M Maas, Judith van Gaalen, Thomas Klockgether, Bart P C van de Warrenbur. The preclinical stage of spinocerebellar ataxias. Neurology. vol 85. issue 1. 2015-09-18. PMID:26062625. |
the autosomal dominant spinocerebellar ataxias (scas) are a heterogeneous group of degenerative diseases of the cerebellum and connected regions. |
2015-09-18 |
2023-08-13 |
human |
| Ravi J Louis, Michelle Lee, Sheng-Han Kuo, Jean-Paul G Vonsattel, Elan D Louis, Phyllis L Faus. Cellular density in the cerebellar molecular layer in essential tremor, spinocerebellar ataxia, and controls. Parkinsonism & related disorders. vol 20. issue 11. 2015-09-04. PMID:25218844. |
cellular density in the cerebellar molecular layer in essential tremor, spinocerebellar ataxia, and controls. |
2015-09-04 |
2023-08-13 |
Not clear |
| Ravi J Louis, Michelle Lee, Sheng-Han Kuo, Jean-Paul G Vonsattel, Elan D Louis, Phyllis L Faus. Cellular density in the cerebellar molecular layer in essential tremor, spinocerebellar ataxia, and controls. Parkinsonism & related disorders. vol 20. issue 11. 2015-09-04. PMID:25218844. |
we quantified cerebellar molecular layer cellular density in 15 et cases, 15 controls, and 7 spinocerebellar ataxia (sca) cases (2:2:1 ratio). |
2015-09-04 |
2023-08-13 |
Not clear |
| Melanie D Mark, Martin Krause, Henk-Jan Boele, Wolfgang Kruse, Stefan Pollok, Thomas Kuner, Deniz Dalkara, Sebastiaan Koekkoek, Chris I De Zeeuw, Stefan Herlitz. Spinocerebellar ataxia type 6 protein aggregates cause deficits in motor learning and cerebellar plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 23. 2015-08-19. PMID:26063920. |
spinocerebellar ataxia type 6 protein aggregates cause deficits in motor learning and cerebellar plasticity. |
2015-08-19 |
2023-08-13 |
mouse |
| Roberto E Mercadillo, Víctor Galvez, Rosalinda Díaz, Carlos Roberto Hernández-Castillo, Aurelio Campos-Romo, Marie-Catherine Boll, Erick H Pasaye, Juan Fernandez-Rui. Parahippocampal gray matter alterations in Spinocerebellar Ataxia Type 2 identified by voxel based morphometry. Journal of the neurological sciences. vol 347. issue 1-2. 2015-08-06. PMID:25263602. |
spinocerebellar ataxia type 2 (sca2) is a genetic disorder causing cerebellar degeneration that result in motor and cognitive alterations. |
2015-08-06 |
2023-08-13 |
human |
| Maria R Stefanescu, Moritz Dohnalek, Stefan Maderwald, Markus Thürling, Martina Minnerop, Andreas Beck, Marc Schlamann, Joern Diedrichsen, Mark E Ladd, Dagmar Timman. Structural and functional MRI abnormalities of cerebellar cortex and nuclei in SCA3, SCA6 and Friedreich's ataxia. Brain : a journal of neurology. vol 138. issue Pt 5. 2015-07-17. PMID:25818870. |
as expected, the volume of the cerebellum was markedly reduced in spinocerebellar ataxia type 6, preserved in friedreich's ataxia, and mildy reduced in spinocerebellar ataxia type 3. |
2015-07-17 |
2023-08-13 |
Not clear |