| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Sun, Bi-Qiu Tang, Fei Zhu, Wen-Jing Zhang, You-Jin Zhao, Qi-Yong Gong, Na Hu, Su Ly. [Anatomic Abnormalities of Hippocampal Subfields in First-Episode Drug-Naïve Schizophrenia and Major Depressive Disorder: A Structural MRI Comparative Study]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 54. issue 2. 2023-03-23. PMID:36949685. |
to compare the structural changes along the longitudinal axis of hippocampus subfields between schizophrenia (scz) patients and major depressive disorder (mdd) patients in the early stage of their scz and mdd. |
2023-03-23 |
2023-08-14 |
Not clear |
| Huaigui Liu, Wei Li, Nana Liu, Jie Tang, Lixin Sun, Jiayuan Xu, Yuan Ji, Yingying Xie, Hao Ding, Zhaoxiang Ye, Chunshui Yu, Wen Qi. Structural covariances of prefrontal subregions selectively associate with dopamine-related gene coexpression and schizophrenia. Cerebral cortex (New York, N.Y. : 1991). 2023-03-19. PMID:36935097. |
based on the brain gene expression dataset from allen human brain atlas and structural magnetic resonance imaging data (ndis = 1727, nrep = 408), we first identified 10 out of 22 pfc subregions whose gray matter volume (gmv) covariance profiles were reliably associated with their da genes coexpression profiles, then four out of the identified 10 pfc subregions demonstrated abnormally increased gmv covariance with the hippocampus, insula, and medial frontal areas in schizophrenia patients (ncase = 100; ncontrol = 102). |
2023-03-19 |
2023-08-14 |
human |
| Huaigui Liu, Wei Li, Nana Liu, Jie Tang, Lixin Sun, Jiayuan Xu, Yuan Ji, Yingying Xie, Hao Ding, Zhaoxiang Ye, Chunshui Yu, Wen Qi. Structural covariances of prefrontal subregions selectively associate with dopamine-related gene coexpression and schizophrenia. Cerebral cortex (New York, N.Y. : 1991). 2023-03-19. PMID:36935097. |
moreover, based on a schizophrenia postmortem expression dataset, we found that the da genes coexpression of schizophrenia was significantly reduced between the middle frontal gyrus and hippocampus, in which 21 da genes showed significantly unsynchronized expression changes, and the 21 genes' brain expression were enriched in brain activity invoked by working memory, reward, speech production, and episodic memory. |
2023-03-19 |
2023-08-14 |
human |
| Bradley S Peterson, Tejal Kaur, Siddhant Sawardekar, Tiziano Colibazzi, Xuejun Hao, Bruce E Wexler, Ravi Bansa. Aberrant hippocampus and amygdala morphology associated with cognitive deficits in schizophrenia. Frontiers in cellular neuroscience. vol 17. 2023-03-13. PMID:36909281. |
aberrant hippocampus and amygdala morphology associated with cognitive deficits in schizophrenia. |
2023-03-13 |
2023-08-14 |
Not clear |
| Bradley S Peterson, Tejal Kaur, Siddhant Sawardekar, Tiziano Colibazzi, Xuejun Hao, Bruce E Wexler, Ravi Bansa. Aberrant hippocampus and amygdala morphology associated with cognitive deficits in schizophrenia. Frontiers in cellular neuroscience. vol 17. 2023-03-13. PMID:36909281. |
we aimed to identify differences in morphology of the hippocampus and amygdala in patients with schizophrenia compared with healthy controls (hcs), and in patients who were either neuropsychologically near normal (npnn) or neuropsychologically impaired (npi). |
2023-03-13 |
2023-08-14 |
Not clear |
| Bradley S Peterson, Tejal Kaur, Siddhant Sawardekar, Tiziano Colibazzi, Xuejun Hao, Bruce E Wexler, Ravi Bansa. Aberrant hippocampus and amygdala morphology associated with cognitive deficits in schizophrenia. Frontiers in cellular neuroscience. vol 17. 2023-03-13. PMID:36909281. |
morphological disturbances in the same subfields of the hippocampus and amygdala, but of greater magnitude in those with npi, would strengthen evidence for the centrality of these limbic regions and working memory deficits in the pathogenesis of schizophrenia. |
2023-03-13 |
2023-08-14 |
Not clear |
| Bruce Atwood, Walid Yassin, Shi Yu Chan, Mei-Hua Hal. Subfield specific longitudinal changes of hippocampal volumes in patients with early stage bipolar disorder. Bipolar disorders. 2023-03-01. PMID:36855850. |
bipolar disorder (bpd) has substantial overlap in symptomatology and genetic liability with schizophrenia (sz), and reduced hippocampal volumes, particularly at the chronic illness stages, are documented in both disorders. |
2023-03-01 |
2023-08-14 |
Not clear |
| Yi Yin, Jinghui Tong, Junchao Huang, Leilei Wang, Baopeng Tian, Song Chen, Shuping Tan, Zhiren Wang, Ting Yu, Yanli Li, Yongsheng Tong, Fengmei Fan, Peter Kochunov, L Elliot Hong, Yunlong Ta. History of suicide attempt associated with amygdala and hippocampus changes among individuals with schizophrenia. European archives of psychiatry and clinical neuroscience. 2023-02-14. PMID:36788147. |
history of suicide attempt associated with amygdala and hippocampus changes among individuals with schizophrenia. |
2023-02-14 |
2023-08-14 |
Not clear |
| Yuan Sun, Na Hu, Mingqi Wang, Lu Lu, Chunyan Luo, Biqiu Tang, Chenyang Yao, John A Sweeney, Qiyong Gong, Changjian Qiu, Su Lu. Hippocampal subfield alterations in schizophrenia and major depressive disorder: a systematic review and network meta-analysis of anatomic MRI studies. Journal of psychiatry & neuroscience : JPN. vol 48. issue 1. 2023-02-07. PMID:36750240. |
hippocampal subfield alterations in schizophrenia and major depressive disorder: a systematic review and network meta-analysis of anatomic mri studies. |
2023-02-07 |
2023-08-14 |
Not clear |
| Yuan Sun, Na Hu, Mingqi Wang, Lu Lu, Chunyan Luo, Biqiu Tang, Chenyang Yao, John A Sweeney, Qiyong Gong, Changjian Qiu, Su Lu. Hippocampal subfield alterations in schizophrenia and major depressive disorder: a systematic review and network meta-analysis of anatomic MRI studies. Journal of psychiatry & neuroscience : JPN. vol 48. issue 1. 2023-02-07. PMID:36750240. |
hippocampal disturbances are important in the pathophysiology of both schizophrenia and major depressive disorder (mdd). |
2023-02-07 |
2023-08-14 |
Not clear |
| Jacob G Pine, Sarah E Paul, Emma Johnson, Ryan Bogdan, Sridhar Kandala, Deanna M Barc. Polygenic Risk for Schizophrenia, Major Depression, and Post-traumatic Stress Disorder and Hippocampal Subregion Volumes in Middle Childhood. Behavior genetics. 2023-01-31. PMID:36720770. |
studies demonstrate that individuals with diagnoses for major depressive disorder (mdd), post-traumatic stress disorder (ptsd), and schizophrenia (scz) may exhibit smaller hippocampal gray matter relative to otherwise healthy controls, although the effect sizes vary in each disorder. |
2023-01-31 |
2023-08-14 |
Not clear |
| Jia Guo, Douglas L Rothman, Scott A Smal. Why Hippocampal Glutamate Levels Are Elevated in Schizophrenia. JAMA psychiatry. 2023-01-25. PMID:36696108. |
why hippocampal glutamate levels are elevated in schizophrenia. |
2023-01-25 |
2023-08-14 |
Not clear |
| Wei Yao, Ping Zhou, Qiujin Yan, Xiulin Wu, Yaru Xia, Wenshi Li, Xuhang Li, Fan Zh. ERVWE1 Reduces Hippocampal Neuron Density and Impairs Dendritic Spine Morphology through Inhibiting Wnt/JNK Non-Canonical Pathway via miR-141-3p in Schizophrenia. Viruses. vol 15. issue 1. 2023-01-21. PMID:36680208. |
ervwe1 reduces hippocampal neuron density and impairs dendritic spine morphology through inhibiting wnt/jnk non-canonical pathway via mir-141-3p in schizophrenia. |
2023-01-21 |
2023-08-14 |
human |
| Wei Yao, Ping Zhou, Qiujin Yan, Xiulin Wu, Yaru Xia, Wenshi Li, Xuhang Li, Fan Zh. ERVWE1 Reduces Hippocampal Neuron Density and Impairs Dendritic Spine Morphology through Inhibiting Wnt/JNK Non-Canonical Pathway via miR-141-3p in Schizophrenia. Viruses. vol 15. issue 1. 2023-01-21. PMID:36680208. |
finally, functional assays showed that ervwe1 induced the abnormalities in hippocampal neuron morphology and spine density through inhibiting wnt/jnk non-canonical pathway via mir-141-3p in schizophrenia. |
2023-01-21 |
2023-08-14 |
human |
| Amanda Kiemes, Maria Elisa Serrano Navacerrada, Eugene Kim, Karen Randall, Camilla Simmons, Loreto Rojo Gonzalez, Marija-Magdalena Petrinovic, David J Lythgoe, Diana Rotaru, Davide Di Censo, Lydiane Hirschler, Emmanuel L Barbier, Anthony C Vernon, James M Stone, Cathy Davies, Diana Cash, Gemma Modino. Erbb4 Deletion From Inhibitory Interneurons Causes Psychosis-Relevant Neuroimaging Phenotypes. Schizophrenia bulletin. 2022-12-27. PMID:36573631. |
conditional deletion of a schizophrenia susceptibility gene, the tyrosine kinase receptor erbb4, from cortical and hippocampal inhibitory interneurons leads to synaptic defects, and behavioral and cognitive phenotypes relevant to psychosis in mice. |
2022-12-27 |
2023-08-14 |
mouse |
| Vicente Molina, Inés Fernández-Linsenbarth, María Queipo-de-Llano, María Teresa Jiménez-Aparicio, Carmen Vallecillo-Adame, Abril Aremy-Gonzaga, Celia de-Andrés-Lobo, María Recio-Barbero, Álvaro Díez, Rosa M Beño-Ruiz-de-la-Sierra, Carmen Martín-Gómez, Javier Sanz-Fuentenebr. Real-life outcomes in biotypes of psychotic disorders based on neurocognitive performance. European archives of psychiatry and clinical neuroscience. 2022-11-23. PMID:36416961. |
in this previous work, the group with larger cognitive deficits (n = 93, including 69 chronic schizophrenia, 17 first episodes (fe) of schizophrenia and 7 bipolar disorder patients) showed smaller thalamus and hippocampus volume and hyper-synchronic electroencephalogram than the group with milder deficits (n = 105, including 58 chronic schizophrenia, 25 fe and 22 bipolar disorder patients). |
2022-11-23 |
2023-08-14 |
Not clear |
| Wei Qi, Julia Marx, Michael Zingman, Yi Li, Eva Petkova, Esther Blessing, Babak Ardekani, Ayse Sakalli Kani, Corinne Cather, Oliver Freudenreich, Daphne Holt, Jingping Zhao, Jijun Wang, Donald C Gof. Hippocampal Subfield Volumes Predict Disengagement from Maintenance Treatment in First Episode Schizophrenia. Schizophrenia bulletin. 2022-11-12. PMID:36370124. |
hippocampal subfield volumes predict disengagement from maintenance treatment in first episode schizophrenia. |
2022-11-12 |
2023-08-14 |
Not clear |
| Gabriella Ferretti, Alessia Romano, Rossana Sirabella, Sara Serafini, Thorsten Jürgen Maier, Carmela Matron. An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation. Cell & bioscience. vol 12. issue 1. 2022-11-09. PMID:36348448. |
this means that alterations in sema 3a signaling might compromise hippocampal and cortical circuits and predispose to disorders such as autism and schizophrenia. |
2022-11-09 |
2023-08-14 |
human |
| In Jun Yeo, Jaesuk Yun, Dong Ju Son, Sang-Bae Han, Maree J Webster, Jin Tae Hong, Sanghyeon Ki. Overexpression of transmembrane TNFα in brain endothelial cells induces schizophrenia-relevant behaviors. Molecular psychiatry. 2022-11-05. PMID:36333582. |
we conducted co-expression networks using publicly available rna-seq data from prefrontal cortex (pfc) and hippocampus (hp) of 64 individuals with schizophrenia and 64 unaffected controls from the smri tissue collections. |
2022-11-05 |
2023-08-14 |
mouse |
| Natsuko Ikeda, Shinichi Yamada, Kasumi Yasuda, Shinya Uenishi, Atsushi Tamaki, Takuya Ishida, Michiyo Tabata, Tomikimi Tsuji, Sohei Kimoto, Shun Takahash. Structural connectivity between the hippocampus and cortical/subcortical area relates to cognitive impairment in schizophrenia but not in mood disorders. Journal of neuropsychology. 2022-10-28. PMID:36305099. |
structural connectivity between the hippocampus and cortical/subcortical area relates to cognitive impairment in schizophrenia but not in mood disorders. |
2022-10-28 |
2023-08-14 |
human |