| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arianna De Rosa, Andrea Fontana, Tommaso Nuzzo, Martina Garofalo, Anna Di Maio, Daniela Punzo, Massimiliano Copetti, Alessandro Bertolino, Francesco Errico, Antonio Rampino, Andrea de Bartolomeis, Alessandro Usiell. Machine Learning algorithm unveils glutamatergic alterations in the post-mortem schizophrenia brain. NPJ schizophrenia. vol 8. issue 1. 2022-02-26. PMID:35217646. |
we investigated in the post-mortem dorsolateral prefrontal cortex (dlpfc) and hippocampus of schizophrenia patients and non-psychiatric controls, the levels of neuroactive d- and l-amino acids (l-glutamate, d-serine, glycine, l-aspartate, d-aspartate) by hplc. |
2022-02-26 |
2023-08-13 |
Not clear |
| Arianna De Rosa, Andrea Fontana, Tommaso Nuzzo, Martina Garofalo, Anna Di Maio, Daniela Punzo, Massimiliano Copetti, Alessandro Bertolino, Francesco Errico, Antonio Rampino, Andrea de Bartolomeis, Alessandro Usiell. Machine Learning algorithm unveils glutamatergic alterations in the post-mortem schizophrenia brain. NPJ schizophrenia. vol 8. issue 1. 2022-02-26. PMID:35217646. |
univariable analyses revealed that none of the investigated molecules was differently represented in the post-mortem dlpfc and hippocampus of schizophrenia patients, compared with controls. |
2022-02-26 |
2023-08-13 |
Not clear |
| Maureen McHugo, Baxter P Rogers, Suzanne N Avery, Kristan Armstrong, Jennifer Urbano Blackford, Simon N Vandekar, Maxwell J Roeske, Neil D Woodward, Stephan Hecker. Increased amplitude of hippocampal low frequency fluctuations in early psychosis: A two-year follow-up study. Schizophrenia research. vol 241. 2022-02-18. PMID:35180665. |
neuroimaging studies have revealed hippocampal hyperactivity in schizophrenia. |
2022-02-18 |
2023-08-13 |
Not clear |
| Georgios Ponirakis, Reem Ghandi, Amani Ahmed, Hoda Gad, Ioannis N Petropoulos, Adnan Khan, Ahmed Elsotouhy, Surjith Vattoth, Mahmoud K M Alshawwaf, Mohamed Adil Shah Khoodoruth, Marwan Ramadan, Anjushri Bhagat, James Currie, Ziyad Mahfoud, Hanadi Al Hamad, Ahmed Own, Peter M Haddad, Majid Alabdulla, Rayaz A Malik, Peter W Woodruf. Abnormal corneal nerve morphology and brain volume in patients with schizophrenia. Scientific reports. vol 12. issue 1. 2022-02-04. PMID:35115592. |
subjects with schizophrenia had lower cognitive function (p ≤ 0.01), corneal nerve fiber density (cnfd), length (cnfl), branch density (cnbd), cnbd:cnfd ratio (p < 0.0001) and cingulate gyrus volume (p < 0.05) but comparable volume of whole brain (p = 0.61), cortical gray matter (p = 0.99), ventricle (p = 0.47), hippocampus (p = 0.10) and amygdala (p = 0.68). |
2022-02-04 |
2023-08-13 |
human |
| Xiaoe Lang, Dongmei Wang, Dachun Chen, Meihong Xiu, Huixia Zhou, Li Wang, Bo Cao, Xiangyang Zhan. Association Between Hippocampal Subfields and Clinical Symptoms of First-Episode and Drug Naive Schizophrenia Patients During 12 Weeks of Risperidone Treatment. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2022-01-31. PMID:35099766. |
association between hippocampal subfields and clinical symptoms of first-episode and drug naive schizophrenia patients during 12 weeks of risperidone treatment. |
2022-01-31 |
2023-08-13 |
human |
| Xiaoe Lang, Dongmei Wang, Dachun Chen, Meihong Xiu, Huixia Zhou, Li Wang, Bo Cao, Xiangyang Zhan. Association Between Hippocampal Subfields and Clinical Symptoms of First-Episode and Drug Naive Schizophrenia Patients During 12 Weeks of Risperidone Treatment. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2022-01-31. PMID:35099766. |
small hippocampal size may be implicated in the pathogenesis and psychopathology of schizophrenia (scz). |
2022-01-31 |
2023-08-13 |
human |
| Kazutaka Ohi, Yukimasa Muto, Kentaro Takai, Shunsuke Sugiyama, Toshiki Shioir. Investigating genetic overlaps of the genetic factor differentiating schizophrenia from bipolar disorder with cognitive function and hippocampal volume. BJPsych open. vol 8. issue 1. 2022-01-26. PMID:35078554. |
investigating genetic overlaps of the genetic factor differentiating schizophrenia from bipolar disorder with cognitive function and hippocampal volume. |
2022-01-26 |
2023-08-13 |
Not clear |
| Kazutaka Ohi, Yukimasa Muto, Kentaro Takai, Shunsuke Sugiyama, Toshiki Shioir. Investigating genetic overlaps of the genetic factor differentiating schizophrenia from bipolar disorder with cognitive function and hippocampal volume. BJPsych open. vol 8. issue 1. 2022-01-26. PMID:35078554. |
we investigated whether the genetic factor differentiating schizophrenia from bipolar disorder is genetically associated with cognitive phenotypes and hippocampal volumes. |
2022-01-26 |
2023-08-13 |
Not clear |
| Bryan W Jenkins, Shoshana Buckhalter, Melissa L Perreault, Jibran Y Khokha. Cannabis Vapor Exposure Alters Neural Circuit Oscillatory Activity in a Neurodevelopmental Model of Schizophrenia: Exploring the Differential Impact of Cannabis Constituents. Schizophrenia bulletin open. vol 3. issue 1. 2022-01-17. PMID:35036917. |
to understand how exposure to cannabis changes schizophrenia-related oscillatory disruptions, we investigated the impact of administering cannabis vapor containing either Δ9-tetrahydrocannabinol (thc) or balanced thc/cannabidiol (cbd) on oscillatory activity in the neonatal ventral hippocampal lesion (nvhl) rat model of schizophrenia. |
2022-01-17 |
2023-08-13 |
rat |
| Kasumi Yasuda, Shinichi Yamada, Shinya Uenishi, Natsuko Ikeda, Atsushi Tamaki, Yuji Ohoshi, Tomikimi Tsuji, Shun Takahash. Hippocampal Subfield Volumes and Cognitive Function in Schizophrenia and Mood Disorders. Neuropsychobiology. 2022-01-16. PMID:35034014. |
hippocampal subfield volumes and cognitive function in schizophrenia and mood disorders. |
2022-01-16 |
2023-08-13 |
Not clear |
| Kasumi Yasuda, Shinichi Yamada, Shinya Uenishi, Natsuko Ikeda, Atsushi Tamaki, Yuji Ohoshi, Tomikimi Tsuji, Shun Takahash. Hippocampal Subfield Volumes and Cognitive Function in Schizophrenia and Mood Disorders. Neuropsychobiology. 2022-01-16. PMID:35034014. |
the hippocampus is relevant to cognitive function in schizophrenia (scz) and mood disorder patients. |
2022-01-16 |
2023-08-13 |
Not clear |
| Sunah Choi, Minah Kim, Hyungyou Park, Taekwan Kim, Sun-Young Moon, Silvia Kyungjin Lho, Junhee Lee, Jun Soo Kwo. Volume deficits in hippocampal subfields in unaffected relatives of schizophrenia patients with high genetic loading but without any psychiatric symptoms. Schizophrenia research. vol 240. 2022-01-09. PMID:34999371. |
volume deficits in hippocampal subfields in unaffected relatives of schizophrenia patients with high genetic loading but without any psychiatric symptoms. |
2022-01-09 |
2023-08-13 |
Not clear |
| Sunah Choi, Minah Kim, Hyungyou Park, Taekwan Kim, Sun-Young Moon, Silvia Kyungjin Lho, Junhee Lee, Jun Soo Kwo. Volume deficits in hippocampal subfields in unaffected relatives of schizophrenia patients with high genetic loading but without any psychiatric symptoms. Schizophrenia research. vol 240. 2022-01-09. PMID:34999371. |
hippocampal volume changes have been reported in schizophrenia patients and their relatives and are proposed to contribute to the pathophysiology of schizophrenia. |
2022-01-09 |
2023-08-13 |
Not clear |
| Stuart A Williams, Miriam Gwilt, Rebecca Hock, Charlotte Taylor, Joanna Loayza, Carl W Stevenson, Helen J Cassaday, Tobias Bas. Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition. eNeuro. 2022-01-04. PMID:34980662. |
consequently, hippocampal neural disinhibition may contribute to impairments in fear conditioning and salience modulation reported in schizophrenia. |
2022-01-04 |
2023-08-13 |
rat |
| Stuart A Williams, Miriam Gwilt, Rebecca Hock, Charlotte Taylor, Joanna Loayza, Carl W Stevenson, Helen J Cassaday, Tobias Bas. Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition. eNeuro. 2022-01-04. PMID:34980662. |
the disruption of fear conditioning resembles aversive conditioning deficits reported in schizophrenia and may reflect a disruption of neural processing both within the hippocampus and in projection sites of the hippocampus. |
2022-01-04 |
2023-08-13 |
rat |
| Jeremy Hall, Nicholas J Bra. Schizophrenia Genomics: Convergence on Synaptic Development, Adult Synaptic Plasticity, or Both? Biological psychiatry. 2022-01-03. PMID:34974922. |
these data provide strong support for the view that synaptic dysfunction within glutamatergic and gabaergic (gamma-aminobutyric acidergic) neurons of the cerebral cortex, hippocampus, and other limbic structures is a central component of schizophrenia pathophysiology. |
2022-01-03 |
2023-08-13 |
Not clear |
| Joshua Hendrikse, Yann Chye, Sarah Thompson, Nigel C Rogasch, Chao Suo, James P Coxon, Murat Yüce. Regular aerobic exercise is positively associated with hippocampal structure and function in young and middle-aged adults. Hippocampus. 2021-12-28. PMID:34961996. |
the hippocampus plays a critical role in memory function, and is altered in a number of psychiatric disorders associated with memory impairments (e.g., depression and schizophrenia), as well as healthy aging. |
2021-12-28 |
2023-08-13 |
Not clear |
| Lavinia Carmen Uscătescu, Lisa Kronbichler, Renate Stelzig-Schöler, Brandy-Gale Pearce, Sarah Said-Yürekli, Luise Antonia Reich, Stefanie Weber, Wolfgang Aichhorn, Martin Kronbichle. Effective Connectivity of the Hippocampus Can Differentiate Patients with Schizophrenia from Healthy Controls: A Spectral DCM Approach. Brain topography. vol 34. issue 6. 2021-12-10. PMID:34482503. |
effective connectivity of the hippocampus can differentiate patients with schizophrenia from healthy controls: a spectral dcm approach. |
2021-12-10 |
2023-08-13 |
Not clear |
| Iluminada Corripio, Alexandra Roldán, Peter McKenna, Salvador Sarró, Anna Alonso-Solís, Laura Salgado, Enric Álvarez, Joan Molet, Edith Pomarol-Clotet, Maria Portell. Target selection for deep brain stimulation in treatment resistant schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 112. 2021-12-10. PMID:34517055. |
the hippocampus is also of theoretical interest but there is no clear functional imaging evidence that it shows overactivity in schizophrenia. |
2021-12-10 |
2023-08-13 |
Not clear |
| Nina Vanessa Kraguljac, Matthew Carle, Michael A Frölich, Steve Tran, Michael A Yassa, David Matthew White, Abhishek Reddy, Adrienne Carol Laht. Mnemonic Discrimination Deficits in First-Episode Psychosis and a Ketamine Model Suggest Dentate Gyrus Pathology Linked to NMDA Receptor Hypofunction. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 6. issue 12. 2021-12-10. PMID:34649019. |
converging evidence from neuroimaging and postmortem studies suggests that hippocampal subfields are differentially affected in schizophrenia. |
2021-12-10 |
2023-08-13 |
Not clear |