| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrée-Anne Ledoux, Patrice Boyer, Jennifer L Phillips, Alain Labelle, Andra Smith, Véronique D Bohbo. Structural hippocampal anomalies in a schizophrenia population correlate with navigation performance on a wayfinding task. Frontiers in behavioral neuroscience. vol 8. 2014-03-27. PMID:24672451. |
structural hippocampal anomalies in a schizophrenia population correlate with navigation performance on a wayfinding task. |
2014-03-27 |
2023-08-12 |
human |
| Andrée-Anne Ledoux, Patrice Boyer, Jennifer L Phillips, Alain Labelle, Andra Smith, Véronique D Bohbo. Structural hippocampal anomalies in a schizophrenia population correlate with navigation performance on a wayfinding task. Frontiers in behavioral neuroscience. vol 8. 2014-03-27. PMID:24672451. |
episodic memory, related to the hippocampus, has been found to be impaired in schizophrenia. |
2014-03-27 |
2023-08-12 |
human |
| Andrée-Anne Ledoux, Patrice Boyer, Jennifer L Phillips, Alain Labelle, Andra Smith, Véronique D Bohbo. Structural hippocampal anomalies in a schizophrenia population correlate with navigation performance on a wayfinding task. Frontiers in behavioral neuroscience. vol 8. 2014-03-27. PMID:24672451. |
further, hippocampal anomalies have also been observed in schizophrenia. |
2014-03-27 |
2023-08-12 |
human |
| Andrée-Anne Ledoux, Patrice Boyer, Jennifer L Phillips, Alain Labelle, Andra Smith, Véronique D Bohbo. Structural hippocampal anomalies in a schizophrenia population correlate with navigation performance on a wayfinding task. Frontiers in behavioral neuroscience. vol 8. 2014-03-27. PMID:24672451. |
this study investigated whether average hippocampal gray matter (gm) would differentiate performance on a hippocampus-dependent memory task in patients with schizophrenia and healthy controls. |
2014-03-27 |
2023-08-12 |
human |
| Andrée-Anne Ledoux, Patrice Boyer, Jennifer L Phillips, Alain Labelle, Andra Smith, Véronique D Bohbo. Structural hippocampal anomalies in a schizophrenia population correlate with navigation performance on a wayfinding task. Frontiers in behavioral neuroscience. vol 8. 2014-03-27. PMID:24672451. |
interestingly, the cuneus and cingulate gyrus also covaried with the hippocampus in the patient group but the orbital frontal cortex did not, supporting the hypothesis of impaired connectivity between the hippocampus and the frontal cortex in schizophrenia. |
2014-03-27 |
2023-08-12 |
human |
| Andrée-Anne Ledoux, Patrice Boyer, Jennifer L Phillips, Alain Labelle, Andra Smith, Véronique D Bohbo. Structural hippocampal anomalies in a schizophrenia population correlate with navigation performance on a wayfinding task. Frontiers in behavioral neuroscience. vol 8. 2014-03-27. PMID:24672451. |
these results present important implications for creating intervention programs aimed at measuring functional and structural changes in the hippocampus in schizophrenia. |
2014-03-27 |
2023-08-12 |
human |
| Bin Ji, Wei Mei, John X Zhang, Juzhen Jing, Qiulin Wu, Yongning Zhuo, Zhuangwei Xia. Abnormal auditory sensory gating-out in first-episode and never-medicated paranoid schizophrenia patients: an fMRI study. Experimental brain research. vol 229. issue 2. 2014-03-25. PMID:23820976. |
different from previous findings, the schizophrenia patients showed decreased activation in hippocampus and thalamus during sensory gating-out, compared with the normal controls. |
2014-03-25 |
2023-08-12 |
Not clear |
| Bin Ji, Wei Mei, John X Zhang, Juzhen Jing, Qiulin Wu, Yongning Zhuo, Zhuangwei Xia. Abnormal auditory sensory gating-out in first-episode and never-medicated paranoid schizophrenia patients: an fMRI study. Experimental brain research. vol 229. issue 2. 2014-03-25. PMID:23820976. |
the results support the theory attributing abnormal sensory gating-out in schizophrenia patients to the dysfunction of hippocampus and thalamus. |
2014-03-25 |
2023-08-12 |
Not clear |
| Behnaz Esmaeili, Anthony A Grac. Afferent drive of medial prefrontal cortex by hippocampus and amygdala is altered in MAM-treated rats: evidence for interneuron dysfunction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 10. 2014-03-24. PMID:23471079. |
using a validated rat model of schizophrenia based on prenatal administration of the mitotoxin methyl azoxymethanol acetate (mam), we examined the convergent projections from the ventral hippocampus (vhipp) and the basolateral amygdala (bla) in the medial prefrontal cortex (mpfc). |
2014-03-24 |
2023-08-12 |
rat |
| Andrew R Mayer, David Ruhl, Flannery Merideth, Josef Ling, Faith M Hanlon, Juan Bustillo, Jose Cañiv. Functional imaging of the hemodynamic sensory gating response in schizophrenia. Human brain mapping. vol 34. issue 9. 2014-03-20. PMID:22461278. |
the cortical (auditory and prefrontal) and/or subcortical (thalamic and hippocampal) generators of abnormal electrophysiological responses during sensory gating remain actively debated in the schizophrenia literature. |
2014-03-20 |
2023-08-12 |
Not clear |
| Robin L Wellington, Robert M Bilder, Barbara Napolitano, Philip R Szeszk. Effects of age on prefrontal subregions and hippocampal volumes in young and middle-aged healthy humans. Human brain mapping. vol 34. issue 9. 2014-03-20. PMID:22488952. |
furthermore, understanding the potential role of sex and age in mediating prefrontal cortical and hippocampal volumes may have strong relevance for psychiatric disorders such as schizophrenia that have implicated neurodevelopmental abnormalities within frontotemporal circuits in their pathogenesis. |
2014-03-20 |
2023-08-12 |
Not clear |
| Melissa A Burt, Yiu Chung Tse, Patricia Boksa, Tak Pan Won. Prenatal immune activation interacts with stress and corticosterone exposure later in life to modulate N-methyl-D-aspartate receptor synaptic function and plasticity. The international journal of neuropsychopharmacology. vol 16. issue 8. 2014-03-14. PMID:23552018. |
prenatal infection could confer susceptibility to schizophrenia through modification of hippocampal nmdar function, with hypofunction in resting conditions and heightened responsiveness to stress, thus impacting the development of the disorder. |
2014-03-14 |
2023-08-12 |
rat |
| Yu Jing, Hu Zhang, Amy R Wolff, David K Bilkey, Ping Li. Altered arginine metabolism in the hippocampus and prefrontal cortex of maternal immune activation rat offspring. Schizophrenia research. vol 148. issue 1-3. 2014-03-10. PMID:23806581. |
the present study measured the levels of l-arginine and its downstream metabolites in the sub-regions of the hippocampus, prefrontal cortex and cerebellum in adult rats that had been exposed to maternal immune activation (mia; a risk factor for schizophrenia). |
2014-03-10 |
2023-08-12 |
rat |
| Desiree D Dickerson, David K Bilke. Aberrant neural synchrony in the maternal immune activation model: using translatable measures to explore targeted interventions. Frontiers in behavioral neuroscience. vol 7. 2014-03-10. PMID:24409130. |
exposure of pregnant dams to poly i:c on gd15 produced an impairment in long-range neural synchrony in adult offspring between two regions implicated in schizophrenia pathology; the hippocampus and the medial prefrontal cortex (mpfc). |
2014-03-10 |
2023-08-12 |
Not clear |
| Nina V Kraguljac, David M White, Meredith A Reid, Adrienne C Laht. Increased hippocampal glutamate and volumetric deficits in unmedicated patients with schizophrenia. JAMA psychiatry. vol 70. issue 12. 2014-02-24. PMID:24108440. |
increased hippocampal glutamate and volumetric deficits in unmedicated patients with schizophrenia. |
2014-02-24 |
2023-08-12 |
Not clear |
| Geraldo F Busatt. Structural and functional neuroimaging studies in major depressive disorder with psychotic features: a critical review. Schizophrenia bulletin. vol 39. issue 4. 2014-02-14. PMID:23615813. |
brain regions seen as critical both to emotional processing and to models of psychotic symptoms, such as the hippocampus, insula, and lateral prefrontal cortex, have been implicated in separate neuroimaging investigations of either schizophrenia or major depression, as well as in some studies that directly compared depressed patients with and without psychotic features. |
2014-02-14 |
2023-08-12 |
human |
| Fábio V Caixeta, Alianda M Cornélio, Robson Scheffer-Teixeira, Sidarta Ribeiro, Adriano B L Tor. Ketamine alters oscillatory coupling in the hippocampus. Scientific reports. vol 3. 2014-02-14. PMID:23907109. |
here we investigated the dynamics of oscillatory coupling in the hippocampus of awake rats upon nmda receptor blockade by ketamine, a pharmacological model of schizophrenia. |
2014-02-14 |
2023-08-12 |
rat |
| Yang Yu, Hui Shen, Ling-Li Zeng, Qiongmin Ma, Dewen H. Convergent and divergent functional connectivity patterns in schizophrenia and depression. PloS one. vol 8. issue 7. 2014-02-07. PMID:23844175. |
the depression and schizophrenia groups both showed altered functional connections associated with the medial prefrontal cortex, anterior cingulate cortex, thalamus, hippocampus, and cerebellum. |
2014-02-07 |
2023-08-12 |
Not clear |
| Sònia Darbra, Laura Modol, Monique Vallée, Marc Pallarè. Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats. Psychoneuroendocrinology. vol 38. issue 8. 2014-01-31. PMID:23294582. |
in order to study whether endogenous neonatal allo levels would be a determinant parameter involved in mediating adult hippocampal gabaa system maturation, we investigated the effects of neonatal finasteride (50mg/kg, sc) treatment and allo (allo; 20mg/kg, sc) supplementation on an animal behavioural model with relevance to neurodevelopmental disorder, such as schizophrenia. |
2014-01-31 |
2023-08-12 |
rat |
| Sònia Darbra, Laura Modol, Monique Vallée, Marc Pallarè. Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats. Psychoneuroendocrinology. vol 38. issue 8. 2014-01-31. PMID:23294582. |
the results obtained in the present study indicate the importance of neonatal neurosteroid levels in the development of hippocampal function and their relevance in a behavioural phenotype that some have likened to that present in schizophrenia. |
2014-01-31 |
2023-08-12 |
rat |