Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Claudia E Schneider, Tonya White, Johanna Hass, Daniel Geisler, Stuart R Wallace, Veit Roessner, Daphne J Holt, Vince D Calhoun, Randy L Gollub, Stefan Ehrlic. Smoking status as a potential confounder in the study of brain structure in schizophrenia. Journal of psychiatric research. vol 50. 2014-10-06. PMID:24373929. |
several but not all mri studies have reported volume reductions in the hippocampus and dorsolateral prefrontal cortex (dlpfc) in patients with schizophrenia. |
2014-10-06 |
2023-08-12 |
Not clear |
Claudia E Schneider, Tonya White, Johanna Hass, Daniel Geisler, Stuart R Wallace, Veit Roessner, Daphne J Holt, Vince D Calhoun, Randy L Gollub, Stefan Ehrlic. Smoking status as a potential confounder in the study of brain structure in schizophrenia. Journal of psychiatric research. vol 50. 2014-10-06. PMID:24373929. |
smoker schizophrenia patients showed significantly lower hippocampal and dlpfc volumes than non-smoker schizophrenia patients. |
2014-10-06 |
2023-08-12 |
Not clear |
Claudia E Schneider, Tonya White, Johanna Hass, Daniel Geisler, Stuart R Wallace, Veit Roessner, Daphne J Holt, Vince D Calhoun, Randy L Gollub, Stefan Ehrlic. Smoking status as a potential confounder in the study of brain structure in schizophrenia. Journal of psychiatric research. vol 50. 2014-10-06. PMID:24373929. |
our data suggest that a proportion of the volume reduction seen in the hippocampus and dlpfc in schizophrenia is associated with smoking rather than with the diagnosis of schizophrenia. |
2014-10-06 |
2023-08-12 |
Not clear |
Y Kunii, T M Hyde, T Ye, C Li, B Kolachana, D Dickinson, D R Weinberger, J E Kleinman, B K Lipsk. Revisiting DARPP-32 in postmortem human brain: changes in schizophrenia and bipolar disorder and genetic associations with t-DARPP-32 expression. Molecular psychiatry. vol 19. issue 2. 2014-10-01. PMID:23295814. |
in this study, we examined the association of expression of two major darpp-32 transcripts, full-length (fl-darpp-32) and truncated (t-darpp-32), with genetic variants of darpp-32 in three brain regions receiving dopaminergic input and implicated in schizophrenia (the dorsolateral prefrontal cortex (dlpfc), hippocampus and caudate) in a much larger set of postmortem samples from patients with schizophrenia, bipolar disorder, major depression and normal controls (>700 subjects). |
2014-10-01 |
2023-08-12 |
human |
S Kühn, T Gleich, R C Lorenz, U Lindenberger, J Gallina. Playing Super Mario induces structural brain plasticity: gray matter changes resulting from training with a commercial video game. Molecular psychiatry. vol 19. issue 2. 2014-10-01. PMID:24166407. |
the presented video game training could therefore be used to counteract known risk factors for mental disease such as smaller hippocampus and prefrontal cortex volume in, for example, post-traumatic stress disorder, schizophrenia and neurodegenerative disease. |
2014-10-01 |
2023-08-12 |
human |
Ian J Orozco, Peter Koppensteiner, Ipe Ninan, Ottavio Aranci. The schizophrenia susceptibility gene DTNBP1 modulates AMPAR synaptic transmission and plasticity in the hippocampus of juvenile DBA/2J mice. Molecular and cellular neurosciences. vol 58. 2014-09-25. PMID:24321452. |
the schizophrenia susceptibility gene dtnbp1 modulates ampar synaptic transmission and plasticity in the hippocampus of juvenile dba/2j mice. |
2014-09-25 |
2023-08-12 |
mouse |
K Sakata, S M Duk. Lack of BDNF expression through promoter IV disturbs expression of monoamine genes in the frontal cortex and hippocampus. Neuroscience. vol 260. 2014-09-25. PMID:24345476. |
mrna levels were measured in the frontal cortex and hippocampus, which are regions related to depression and schizophrenia and where promoter iv is active. |
2014-09-25 |
2023-08-12 |
mouse |
Kristin M Wildeboer-Andrud, Lijun Zheng, Kevin S Choo, Karen E Steven. Cotinine impacts sensory processing in DBA/2 mice through changes in the conditioning amplitude. Pharmacology, biochemistry, and behavior. vol 117. 2014-09-25. PMID:24374321. |
these mice spontaneously show a deficit in hippocampal sensory inhibition, as assessed by the p20-n40 eeg paradigm, which models the deficit observed in schizophrenia patients. |
2014-09-25 |
2023-08-12 |
mouse |
K M Allen, S J Fung, D A Rothmond, P L Noble, C Shannon Weicker. Gonadectomy increases neurogenesis in the male adolescent rhesus macaque hippocampus. Hippocampus. vol 24. issue 2. 2014-09-23. PMID:24123729. |
our findings are in contrast to existing studies in adults where testosterone tends to be a pro-survival factor and demonstrate that testicular hormones may reduce hippocampal neurogenesis during the age typical of schizophrenia onset. |
2014-09-23 |
2023-08-12 |
monkey |
Xiaofeng Guo, Jun Li, Juan Wang, Xiaoduo Fan, Maorong Hu, Yidong Shen, Huafu Chen, Jingping Zha. Hippocampal and orbital inferior frontal gray matter volume abnormalities and cognitive deficit in treatment-naive, first-episode patients with schizophrenia. Schizophrenia research. vol 152. issue 2-3. 2014-09-23. PMID:24439000. |
hippocampal and orbital inferior frontal gray matter volume abnormalities and cognitive deficit in treatment-naive, first-episode patients with schizophrenia. |
2014-09-23 |
2023-08-12 |
Not clear |
W Bailey Glen, Bryant Horowitz, Gregory C Carlson, Tyrone D Cannon, Konrad Talbot, J David Jentsch, Antonieta Lavi. Dysbindin-1 loss compromises NMDAR-dependent synaptic plasticity and contextual fear conditioning. Hippocampus. vol 24. issue 2. 2014-09-23. PMID:24446171. |
taken together, these results indicate that a loss of dysbindin-1 impairs hippocampal plasticity which may, in part, explain the role dysbindin-1 plays in the cognitive impairments of schizophrenia. |
2014-09-23 |
2023-08-12 |
mouse |
Luanna Dixson, Henrik Walter, Michael Schneider, Susanne Erk, Axel Schäfer, Leila Haddad, Oliver Grimm, Manuel Mattheisen, Markus M Nöthen, Sven Cichon, Stephanie H Witt, Marcella Rietschel, Sebastian Mohnke, Nina Seiferth, Andreas Heinz, Heike Tost, Andreas Meyer-Lindenber. Identification of gene ontologies linked to prefrontal-hippocampal functional coupling in the human brain. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 26. 2014-09-23. PMID:24979789. |
functional interactions between the dorsolateral prefrontal cortex and hippocampus during working memory have been studied extensively as an intermediate phenotype for schizophrenia. |
2014-09-23 |
2023-08-13 |
human |
Guolin Ma, Tianbin Song, Min Chen, Yuan Fu, Yong Xu, Ensen Ma, Wu Wang, Jiang Du, Mingxiong Huan. Hippocampal and thalamic neuronal metabolism in a putative rat model of schizophrenia. Neural regeneration research. vol 8. issue 26. 2014-09-10. PMID:25206551. |
hippocampal and thalamic neuronal metabolism in a putative rat model of schizophrenia. |
2014-09-10 |
2023-08-13 |
rat |
Guolin Ma, Tianbin Song, Min Chen, Yuan Fu, Yong Xu, Ensen Ma, Wu Wang, Jiang Du, Mingxiong Huan. Hippocampal and thalamic neuronal metabolism in a putative rat model of schizophrenia. Neural regeneration research. vol 8. issue 26. 2014-09-10. PMID:25206551. |
we developed a putative rat model of schizophrenia by transfecting lentiviral particles carrying the egr3 gene into bilateral hippocampal dentate gyrus. |
2014-09-10 |
2023-08-13 |
rat |
Guolin Ma, Tianbin Song, Min Chen, Yuan Fu, Yong Xu, Ensen Ma, Wu Wang, Jiang Du, Mingxiong Huan. Hippocampal and thalamic neuronal metabolism in a putative rat model of schizophrenia. Neural regeneration research. vol 8. issue 26. 2014-09-10. PMID:25206551. |
this study is the first to report evaluation of brain metabolites using 3.0 t proton magnetic resonance spectroscopy in rats transfected with egr3, and reveals metabolic abnormalities in the hippocampus and thalamus in this putative model of schizophrenia. |
2014-09-10 |
2023-08-13 |
rat |
Ian Mathew, Tova M Gardin, Neeraj Tandon, Shaun Eack, Alan N Francis, Larry J Seidman, Brett Clementz, Godfrey D Pearlson, John A Sweeney, Carol A Tamminga, Matcheri S Keshava. Medial temporal lobe structures and hippocampal subfields in psychotic disorders: findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study. JAMA psychiatry. vol 71. issue 7. 2014-08-27. PMID:24828364. |
structural alterations in the hippocampus and other medial temporal lobe regions have been observed in schizophrenia. |
2014-08-27 |
2023-08-13 |
Not clear |
Madeleine V King, Nisha Kurian, Si Qin, Nektaria Papadopoulou, Ben H C Westerink, Thomas I Cremers, Mark P Epping-Jordan, Emmanuel Le Poul, David E Ray, Kevin C F Fone, David A Kendall, Charles A Marsden, Tyson V Shar. Lentiviral delivery of a vesicular glutamate transporter 1 (VGLUT1)-targeting short hairpin RNA vector into the mouse hippocampus impairs cognition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 2. 2014-08-21. PMID:24037344. |
this study utilized novel lentiviral short hairpin rna (shrna) vectors to target expression of the vesicular glutamate transporter 1 (vglut1) following injection into the dorsal hippocampus of adult mice, as partial reductions in vglut1 expression should attenuate glutamatergic signaling and similar reductions have been reported in schizophrenia. |
2014-08-21 |
2023-08-12 |
mouse |
A M Barr, C H Wu, C Wong, C Hercher, E Töpfer, H N Boyda, R M Procyshyn, W G Honer, C L Beasle. Effects of chronic exercise and treatment with the antipsychotic drug olanzapine on hippocampal volume in adult female rats. Neuroscience. vol 255. 2014-08-14. PMID:24141179. |
numerous studies have reported that the hippocampus in schizophrenia patients is reduced in volume compared to the normal population. |
2014-08-14 |
2023-08-12 |
rat |
J Houenou, M-A d'Albis, C Daban, N Hamdani, M Delavest, J P Lepine, F-E Vederine, S Carde, M Lajnef, C Cabon, F Dickerson, R H Yolken, R Tamouza, C Poupon, M Leboye. Cytomegalovirus seropositivity and serointensity are associated with hippocampal volume and verbal memory in schizophrenia and bipolar disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 48. 2014-08-01. PMID:24083998. |
cytomegalovirus seropositivity and serointensity are associated with hippocampal volume and verbal memory in schizophrenia and bipolar disorder. |
2014-08-01 |
2023-08-12 |
Not clear |
J Houenou, M-A d'Albis, C Daban, N Hamdani, M Delavest, J P Lepine, F-E Vederine, S Carde, M Lajnef, C Cabon, F Dickerson, R H Yolken, R Tamouza, C Poupon, M Leboye. Cytomegalovirus seropositivity and serointensity are associated with hippocampal volume and verbal memory in schizophrenia and bipolar disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 48. 2014-08-01. PMID:24083998. |
we hypothesized that cmv seropositivity and serointensity would be associated with hippocampal volume and cognitive functioning in patients with schizophrenia or bipolar disorder. |
2014-08-01 |
2023-08-12 |
Not clear |