| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guy Sandner, Marie-Josée Angst, Thierry Guiberteau, Blandine Guignard, Astrid Nehli. Effects of caffeine or RX821002 in rats with a neonatal ventral hippocampal lesion. Frontiers in behavioral neuroscience. vol 8. 2014-01-30. PMID:24478661. |
rats with a neonatal ventral hippocampal lesion (nvhl) are used to model schizophrenia. |
2014-01-30 |
2023-08-12 |
rat |
| R A Chambers, J N McClintick, A M Sentir, S A Berg, M Runyan, K H Choi, H J Edenber. Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization. Genes, brain, and behavior. vol 12. issue 5. 2014-01-27. PMID:23682998. |
neonatal ventral hippocampal lesions (nvhl) model this dual diagnosis causality by producing a schizophrenia syndrome with enhanced responsiveness to addictive drugs. |
2014-01-27 |
2023-08-12 |
rat |
| Thomas W Scheewe, Neeltje E M van Haren, Gayane Sarkisyan, Hugo G Schnack, Rachel M Brouwer, Maria de Glint, Hilleke E Hulshoff Pol, Frank J G Backx, René S Kahn, Wiepke Cah. Exercise therapy, cardiorespiratory fitness and their effect on brain volumes: a randomised controlled trial in patients with schizophrenia and healthy controls. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 7. 2014-01-23. PMID:22981376. |
the objective of this study was to examine exercise effects on global brain volume, hippocampal volume, and cortical thickness in schizophrenia patients and healthy controls. |
2014-01-23 |
2023-08-12 |
human |
| Vanessa Suazo, Álvaro Díez, Pilar Tamayo, Carlos Montes, Vicente Molin. Limbic hyperactivity associated to verbal memory deficit in schizophrenia. Journal of psychiatric research. vol 47. issue 6. 2014-01-21. PMID:23490064. |
in schizophrenia there seems to be an inefficient activation of prefrontal and hippocampal regions. |
2014-01-21 |
2023-08-12 |
Not clear |
| Vanessa Suazo, Álvaro Díez, Pilar Tamayo, Carlos Montes, Vicente Molin. Limbic hyperactivity associated to verbal memory deficit in schizophrenia. Journal of psychiatric research. vol 47. issue 6. 2014-01-21. PMID:23490064. |
patients with schizophrenia showed an increased perfusion in the right hippocampus with respect to healthy controls, they also displayed a statistically significant inverse association between perfusion in the left hippocampus and verbal memory performance. |
2014-01-21 |
2023-08-12 |
Not clear |
| Ivan I Kirov, Caitlin J Hardy, Kant Matsuda, Julie Messinger, Ceylan Z Cankurtaran, Melina Warren, Graham C Wiggins, Nissa N Perry, James S Babb, Raymond R Goetz, Ajax George, Dolores Malaspina, Oded Gone. In vivo 7 Tesla imaging of the dentate granule cell layer in schizophrenia. Schizophrenia research. vol 147. issue 2-3. 2014-01-17. PMID:23664589. |
the hippocampus is central to the pathophysiology of schizophrenia. |
2014-01-17 |
2023-08-12 |
human |
| Stephanie M Perez, Amiksha Shah, Amber Asher, Daniel J Lodg. Hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia. The international journal of neuropsychopharmacology. vol 16. issue 6. 2014-01-15. PMID:23190686. |
hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia. |
2014-01-15 |
2023-08-12 |
human |
| Stephanie M Perez, Amiksha Shah, Amber Asher, Daniel J Lodg. Hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia. The international journal of neuropsychopharmacology. vol 16. issue 6. 2014-01-15. PMID:23190686. |
recent preclinical investigations and human imaging studies have proposed that the augmented dopamine system function observed in schizophrenia patients may be secondary to aberrant hippocampal activity. |
2014-01-15 |
2023-08-12 |
human |
| Stephanie M Perez, Amiksha Shah, Amber Asher, Daniel J Lodg. Hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia. The international journal of neuropsychopharmacology. vol 16. issue 6. 2014-01-15. PMID:23190686. |
thus, we posit that the hippocampus represents a novel therapeutic target for the treatment of schizophrenia. |
2014-01-15 |
2023-08-12 |
human |
| Stephanie M Perez, Amiksha Shah, Amber Asher, Daniel J Lodg. Hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia. The international journal of neuropsychopharmacology. vol 16. issue 6. 2014-01-15. PMID:23190686. |
here we provide evidence of the effectiveness of a unique approach aimed at decreasing hippocampal function in a rodent model of schizophrenia. |
2014-01-15 |
2023-08-12 |
human |
| Stephanie M Perez, Amiksha Shah, Amber Asher, Daniel J Lodg. Hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia. The international journal of neuropsychopharmacology. vol 16. issue 6. 2014-01-15. PMID:23190686. |
therefore, we have provided initial preclinical evidence demonstrating the feasibility of hippocampal dbs as a potential novel approach for the treatment of schizophrenia. |
2014-01-15 |
2023-08-12 |
human |
| Junghyup Suh, David J Foster, Heydar Davoudi, Matthew A Wilson, Susumu Tonegaw. Impaired hippocampal ripple-associated replay in a mouse model of schizophrenia. Neuron. vol 80. issue 2. 2014-01-09. PMID:24139046. |
impaired hippocampal ripple-associated replay in a mouse model of schizophrenia. |
2014-01-09 |
2023-08-12 |
mouse |
| Junghyup Suh, David J Foster, Heydar Davoudi, Matthew A Wilson, Susumu Tonegaw. Impaired hippocampal ripple-associated replay in a mouse model of schizophrenia. Neuron. vol 80. issue 2. 2014-01-09. PMID:24139046. |
we recorded neural activity in the hippocampus of freely behaving mice that had a forebrain-specific knockout of the synaptic plasticity-mediating phosphatase calcineurin and were previously shown to exhibit behavioral and cognitive abnormalities, recapitulating the symptoms of schizophrenia. |
2014-01-09 |
2023-08-12 |
mouse |
| D P Eisenberg, A M Ianni, S-M Wei, P D Kohn, B Kolachana, J Apud, D R Weinberger, K F Berma. Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23319002. |
brain-derived neurotrophic factor (bdnf) val(66)met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. |
2014-01-03 |
2023-08-12 |
human |
| D P Eisenberg, A M Ianni, S-M Wei, P D Kohn, B Kolachana, J Apud, D R Weinberger, K F Berma. Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23319002. |
several clinical genetic association studies along with multi-modal evidence for hippocampal dysfunction in schizophrenia indirectly suggest a relationship between schizophrenia and genetically determined bdnf function in the hippocampus. |
2014-01-03 |
2023-08-12 |
human |
| D P Eisenberg, A M Ianni, S-M Wei, P D Kohn, B Kolachana, J Apud, D R Weinberger, K F Berma. Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23319002. |
to directly test this hypothesized relationship, we studied 47 medication-free patients with schizophrenia or schizoaffective disorder and 74 healthy comparison individuals with genotyping for the val(66)met snp and [(15)o]h(2)o positron emission tomography (pet) to measure resting and working memory-related hippocampal regional cerebral blood flow (rcbf). |
2014-01-03 |
2023-08-12 |
human |
| D P Eisenberg, A M Ianni, S-M Wei, P D Kohn, B Kolachana, J Apud, D R Weinberger, K F Berma. Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23319002. |
thus, both task-independent and task-dependent hippocampal neurophysiology accommodates a met allelic background differently in patients with schizophrenia than in control subjects. |
2014-01-03 |
2023-08-12 |
human |
| D P Eisenberg, A M Ianni, S-M Wei, P D Kohn, B Kolachana, J Apud, D R Weinberger, K F Berma. Hippocampal dysfunction in schizophrenia: association with brain-derived neurotrophic factor genotype. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23698315. |
hippocampal dysfunction in schizophrenia: association with brain-derived neurotrophic factor genotype. |
2014-01-03 |
2023-08-12 |
Not clear |
| N A Uranova, N S Kolomeets, O V Vikhreva, I S Zimina, V I Rachmanova, D D Orlovskay. [Ultrastructural pathology of myelinated fibers in schizophrenia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 113. issue 9. 2013-12-31. PMID:24107883. |
an electron microscopic morphometric study of myelinated fibers and proportions of pathological myelinated fibers in postmortem prefrontal cortex, caudate nucleus and hippocampus was performed in 25 cases with schizophrenia and 25 normal controls. |
2013-12-31 |
2023-08-12 |
Not clear |
| M Mizuno, H Sotoyama, H Namba, M Shibuya, T Eda, R Wang, T Okubo, K Nagata, Y Iwakura, H Naw. ErbB inhibitors ameliorate behavioral impairments of an animal model for schizophrenia: implication of their dopamine-modulatory actions. Translational psychiatry. vol 3. 2013-12-23. PMID:23632456. |
although erbb kinase inhibitors ameliorate behavioral deficits of the schizophrenia model that was established by hippocampal lesioning of rat pups, the antipsychotic action of erbb kinase inhibitors and its general applicability to other models are not fully characterized. |
2013-12-23 |
2023-08-12 |
rat |