| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kirsten E Schoonover, Charlene B Farmer, Charity J Morgan, Vidushi Sinha, Laura Odom, Rosalinda C Robert. Abnormalities in the copper transporter CTR1 in postmortem hippocampus in schizophrenia: A subregion and laminar analysis. Schizophrenia research. vol 228. 2021-06-16. PMID:33434736. |
using semi-quantitative immunohistochemistry for dysbindin1 and ctr1, we measured the optical density in a layer specific fashion in the hippocampus and entorhinal cortex in ten subjects with schizophrenia and ten comparison subjects. |
2021-06-16 |
2023-08-13 |
human |
| Aaron Gordon, Annika Forsingdal, Ib Vestergaard Klewe, Jacob Nielsen, Michael Didriksen, Thomas Werge, Daniel H Geschwin. Transcriptomic networks implicate neuronal energetic abnormalities in three mouse models harboring autism and schizophrenia-associated mutations. Molecular psychiatry. vol 26. issue 5. 2021-06-11. PMID:31705054. |
we analyzed the transcriptome from the cortex and hippocampus of three mouse lines modeling human copy number variants (cnvs) associated with schizophrenia and asd: df(h15q13)/+, df(h22q11)/+, and df(h1q21)/+ which carry the 15q13.3 deletion, 22q11.2 deletion, and 1q21.1 deletion, respectively. |
2021-06-11 |
2023-08-13 |
mouse |
| Edmund T Rolls, Wei Cheng, Matthieu Gilson, Weikang Gong, Gustavo Deco, Chun-Yi Zac Lo, Albert C Yang, Shih-Jen Tsai, Mu-En Liu, Ching-Po Lin, Jianfeng Fen. Beyond the disconnectivity hypothesis of schizophrenia. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 3. 2021-06-09. PMID:31381086. |
further, higher ec in schizophrenia was found from the precuneus and posterior cingulate cortex (pcc) to areas such as the parahippocampal, hippocampal, temporal, fusiform, and occipital cortices. |
2021-06-09 |
2023-08-13 |
human |
| Edmund T Rolls, Wei Cheng, Matthieu Gilson, Weikang Gong, Gustavo Deco, Chun-Yi Zac Lo, Albert C Yang, Shih-Jen Tsai, Mu-En Liu, Ching-Po Lin, Jianfeng Fen. Beyond the disconnectivity hypothesis of schizophrenia. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 3. 2021-06-09. PMID:31381086. |
further, a signal variance parameter was increased for areas that included the parahippocampal gyrus and hippocampus, consistent with the hypothesis that hippocampal overactivity is involved in schizophrenia. |
2021-06-09 |
2023-08-13 |
human |
| Johanna Seitz-Holland, Magdalena Seethaler, Nikos Makris, Jarrett Rushmore, Kang-Ik K Cho, Elizabeth Rizzoni, Mark Vangel, Olcay Senay Sahin, Carina Heller, Ofer Pasternak, Filip Szczepankiewicz, Carl-Fredrik Westin, Jan Lošák, Libor Ustohal, Josef Tomandl, Lubomír Vojtíšek, Petr Kudlička, Martin Jáni, T Wilson Woo, Tomáš Kašpárek, Zora Kikinis, Marek Kubick. The association of matrix metalloproteinase 9 (MMP9) with hippocampal volume in schizophrenia: a preliminary MRI study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-06-08. PMID:33833403. |
the association of matrix metalloproteinase 9 (mmp9) with hippocampal volume in schizophrenia: a preliminary mri study. |
2021-06-08 |
2023-08-13 |
human |
| Johanna Seitz-Holland, Magdalena Seethaler, Nikos Makris, Jarrett Rushmore, Kang-Ik K Cho, Elizabeth Rizzoni, Mark Vangel, Olcay Senay Sahin, Carina Heller, Ofer Pasternak, Filip Szczepankiewicz, Carl-Fredrik Westin, Jan Lošák, Libor Ustohal, Josef Tomandl, Lubomír Vojtíšek, Petr Kudlička, Martin Jáni, T Wilson Woo, Tomáš Kašpárek, Zora Kikinis, Marek Kubick. The association of matrix metalloproteinase 9 (MMP9) with hippocampal volume in schizophrenia: a preliminary MRI study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-06-08. PMID:33833403. |
this, combined with evidence for disrupted hippocampal structure and function in schizophrenia, has prompted our current investigation into the relationship between mmp9 and hippocampal volumes in schizophrenia. |
2021-06-08 |
2023-08-13 |
human |
| Sinead E Shortall, Angus M Brown, Eliot Newton-Mann, Erin Dawe-Lane, Chanelle Evans, Maxine Fowler, Madeleine V Kin. Calbindin Deficits May Underlie Dissociable Effects of 5-HT Molecular neurobiology. vol 57. issue 8. 2021-06-07. PMID:32533466. |
glutamatergic dysfunction contributes to schizophrenia pathophysiology and may represent a treatment target, so we used enzyme-based microsensors to evaluate basal- and drug-evoked glutamate release in hippocampal slices from rats that received neonatal pcp and/or isolation rearing. |
2021-06-07 |
2023-08-13 |
rat |
| Natalia Tesli, Dennis van der Meer, Jaroslav Rokicki, Guttorm Storvestre, Cato Røsæg, Arvid Jensen, Gabriela Hjell, Christina Bell, Thomas Fischer-Vieler, Martin Tesli, Ole A Andreassen, Ingrid Melle, Ingrid Agartz, Unn K Haukvi. Hippocampal subfield and amygdala nuclei volumes in schizophrenia patients with a history of violence. European archives of psychiatry and clinical neuroscience. vol 270. issue 6. 2021-06-03. PMID:31980898. |
hippocampal subfield and amygdala nuclei volumes in schizophrenia patients with a history of violence. |
2021-06-03 |
2023-08-13 |
Not clear |
| Wei Qi, Esther Blessing, Chenxiang Li, Babak A Ardekani, Kamber L Hart, Julia Marx, Oliver Freudenreich, Corinne Cather, Daphne Holt, Iruma Bello, Erica D Diminich, Yingying Tang, Michelle Worthington, Botao Zeng, Renrong Wu, Xiaoduo Fan, Andrea Troxel, Jingping Zhao, Jijun Wang, Donald C Gof. Effect of citalopram on hippocampal volume in first-episode schizophrenia: Structural MRI results from the DECIFER trial. Psychiatry research. Neuroimaging. vol 312. 2021-05-20. PMID:33857750. |
effect of citalopram on hippocampal volume in first-episode schizophrenia: structural mri results from the decifer trial. |
2021-05-20 |
2023-08-13 |
Not clear |
| Wei Qi, Esther Blessing, Chenxiang Li, Babak A Ardekani, Kamber L Hart, Julia Marx, Oliver Freudenreich, Corinne Cather, Daphne Holt, Iruma Bello, Erica D Diminich, Yingying Tang, Michelle Worthington, Botao Zeng, Renrong Wu, Xiaoduo Fan, Andrea Troxel, Jingping Zhao, Jijun Wang, Donald C Gof. Effect of citalopram on hippocampal volume in first-episode schizophrenia: Structural MRI results from the DECIFER trial. Psychiatry research. Neuroimaging. vol 312. 2021-05-20. PMID:33857750. |
hippocampal volume loss is prominent in first episode schizophrenia (fes) and has been associated with poor clinical outcomes and with bdnf genotype; antidepressants are believed to reverse hippocampal volume loss via release of bdnf. |
2021-05-20 |
2023-08-13 |
Not clear |
| Chris Greene, Nicole Hanley, Matthew Campbel. Blood-brain barrier associated tight junction disruption is a hallmark feature of major psychiatric disorders. Translational psychiatry. vol 10. issue 1. 2021-05-18. PMID:33139732. |
using immunohistochemistry and qrt-pcr, we show that the expression of claudin-5 is reduced in the hippocampus of individuals diagnosed with major depression or schizophrenia. |
2021-05-18 |
2023-08-13 |
human |
| Esther M Blessing, Vishnu P Murty, Botao Zeng, Jijun Wang, Lila Davachi, Donald C Gof. Anterior Hippocampal-Cortical Functional Connectivity Distinguishes Antipsychotic Naïve First-Episode Psychosis Patients From Controls and May Predict Response to Second-Generation Antipsychotic Treatment. Schizophrenia bulletin. vol 46. issue 3. 2021-05-14. PMID:31433843. |
converging evidence implicates the anterior hippocampus in the proximal pathophysiology of schizophrenia. |
2021-05-14 |
2023-08-13 |
Not clear |
| Yang Du, Xue-Song Li, Lei Chen, Guang-Yang Chen, Yong Chen. A Network Analysis of Epigenetic and Transcriptional Regulation in a Neurodevelopmental Rat Model of Schizophrenia With Implications for Translational Research. Schizophrenia bulletin. vol 46. issue 3. 2021-05-14. PMID:31738422. |
therefore, this study examines epigenetic and transcriptional dysregulation in the prefrontal cortex and hippocampus of mam rats as these are brain regions closely associated with schizophrenia pathogenesis. |
2021-05-14 |
2023-08-13 |
rat |
| Brian J Miller, Karl-Heinz Herzig, Jari Jokelainen, Toni Karhu, Sirkka Keinänen-Kiukaanniemi, Marjo-Riitta Järvelin, Juha Veijola, Heimo Viinamäki, Päivikki Tanskanen, Erika Jääskeläinen, Matti Isohanni, Markku Timone. Inflammation, hippocampal volume, and cognition in schizophrenia: results from the Northern Finland Birth Cohort 1966. European archives of psychiatry and clinical neuroscience. vol 271. issue 4. 2021-05-14. PMID:32382794. |
inflammation, hippocampal volume, and cognition in schizophrenia: results from the northern finland birth cohort 1966. |
2021-05-14 |
2023-08-13 |
human |
| Brian J Miller, Karl-Heinz Herzig, Jari Jokelainen, Toni Karhu, Sirkka Keinänen-Kiukaanniemi, Marjo-Riitta Järvelin, Juha Veijola, Heimo Viinamäki, Päivikki Tanskanen, Erika Jääskeläinen, Matti Isohanni, Markku Timone. Inflammation, hippocampal volume, and cognition in schizophrenia: results from the Northern Finland Birth Cohort 1966. European archives of psychiatry and clinical neuroscience. vol 271. issue 4. 2021-05-14. PMID:32382794. |
in both schizophrenia and controls, higher blood il-6 levels were predictors of smaller hippocampal volumes, but not cognitive performance at age 34. |
2021-05-14 |
2023-08-13 |
human |
| Brian J Miller, Karl-Heinz Herzig, Jari Jokelainen, Toni Karhu, Sirkka Keinänen-Kiukaanniemi, Marjo-Riitta Järvelin, Juha Veijola, Heimo Viinamäki, Päivikki Tanskanen, Erika Jääskeläinen, Matti Isohanni, Markku Timone. Inflammation, hippocampal volume, and cognition in schizophrenia: results from the Northern Finland Birth Cohort 1966. European archives of psychiatry and clinical neuroscience. vol 271. issue 4. 2021-05-14. PMID:32382794. |
we found evidence for increased il-6 levels in patients with midlife schizophrenia from a population-based birth cohort, and replicated associations between il-6 levels and hippocampal volumes. |
2021-05-14 |
2023-08-13 |
human |
| Tadasu Horai, Shuken Boku, Satoshi Okazaki, Ikuo Otsuka, Woraphat Ratta-Apha, Kentaro Mouri, Naruhisa Yamaki, Takashi Hirata, Akitoyo Hishimot. miR-19b is elevated in peripheral blood of schizophrenic patients and attenuates proliferation of hippocampal neural progenitor cells. Journal of psychiatric research. vol 131. 2021-05-14. PMID:32950706. |
these results suggest that the level of mir-19b in peripheral blood is a potential biomarker of schizophrenia and that the higher level of mir-19b may increase the vulnerability of sz via attenuating proliferation of hippocampal npc. |
2021-05-14 |
2023-08-13 |
mouse |
| Huimei An, Jun Qin, Hongzhen Fan, Fengmei Fan, Shuping Tan, Zhiren Wang, Jing Shi, Fude Yang, Yunlong Tan, Xu-Feng Huan. Decreased serum NCAM is positively correlated with hippocampal volumes and negatively correlated with positive symptoms in first-episode schizophrenia patients. Journal of psychiatric research. vol 131. 2021-05-14. PMID:32950707. |
decreased serum ncam is positively correlated with hippocampal volumes and negatively correlated with positive symptoms in first-episode schizophrenia patients. |
2021-05-14 |
2023-08-13 |
Not clear |
| Huimei An, Jun Qin, Hongzhen Fan, Fengmei Fan, Shuping Tan, Zhiren Wang, Jing Shi, Fude Yang, Yunlong Tan, Xu-Feng Huan. Decreased serum NCAM is positively correlated with hippocampal volumes and negatively correlated with positive symptoms in first-episode schizophrenia patients. Journal of psychiatric research. vol 131. 2021-05-14. PMID:32950707. |
this study investigated the relationship between the serum ncam concentrations and hippocampal volume and psychotic symptoms in first-episode drug naïve schizophrenia (fes) patients. |
2021-05-14 |
2023-08-13 |
Not clear |
| Ellen Ji, Cynthia Shannon Weickert, Tertia Purves-Tyson, Christopher White, David J Handelsman, Reena Desai, Maryanne O'Donnell, Dennis Liu, Cherrie Galletly, Rhoshel Lenroot, Thomas W Weicker. Cortisol-dehydroepiandrosterone ratios are inversely associated with hippocampal and prefrontal brain volume in schizophrenia. Psychoneuroendocrinology. vol 123. 2021-04-30. PMID:33169678. |
cortisol-dehydroepiandrosterone ratios are inversely associated with hippocampal and prefrontal brain volume in schizophrenia. |
2021-04-30 |
2023-08-13 |
Not clear |