| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Georg Juckel, Paraskevi Mavrogiorgo. [Traumatization and Schizophrenic Disorders - A Multidimensional View]. Fortschritte der Neurologie-Psychiatrie. 2021-08-13. PMID:34388829. |
patients with schizophrenia as well as those with posttraumatic stress disorder (ptsd) are characterized by brain morphological changes (mygdala und hippocampus). |
2021-08-13 |
2023-08-13 |
Not clear |
| Mei Hong Xiu, XiaoE Lang, Da Chun Chen, Bo Cao, Thomas R Kosten, Raymond Y Cho, Hui Shi, Chang Wei Wei, An Shi Wu, Xiang Yang Zhan. Cognitive Deficits and Clinical Symptoms with Hippocampal Subfields in First-Episode and Never-Treated Patients with Schizophrenia. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 1. 2021-08-11. PMID:32901269. |
cognitive deficits and clinical symptoms with hippocampal subfields in first-episode and never-treated patients with schizophrenia. |
2021-08-11 |
2023-08-13 |
Not clear |
| Mei Hong Xiu, XiaoE Lang, Da Chun Chen, Bo Cao, Thomas R Kosten, Raymond Y Cho, Hui Shi, Chang Wei Wei, An Shi Wu, Xiang Yang Zhan. Cognitive Deficits and Clinical Symptoms with Hippocampal Subfields in First-Episode and Never-Treated Patients with Schizophrenia. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 1. 2021-08-11. PMID:32901269. |
memory dysfunction and associated hippocampal disturbances play crucial roles in cognitive impairment of schizophrenia. |
2021-08-11 |
2023-08-13 |
Not clear |
| Mei Hong Xiu, XiaoE Lang, Da Chun Chen, Bo Cao, Thomas R Kosten, Raymond Y Cho, Hui Shi, Chang Wei Wei, An Shi Wu, Xiang Yang Zhan. Cognitive Deficits and Clinical Symptoms with Hippocampal Subfields in First-Episode and Never-Treated Patients with Schizophrenia. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 1. 2021-08-11. PMID:32901269. |
to examine the relationships between cognitive function and the hippocampal subfields (hss) in first-episode never-treated (fent) schizophrenia patients, the hss were segmented in 39 fent patients and 30 healthy controls using a state-of the-art automated algorithm. |
2021-08-11 |
2023-08-13 |
Not clear |
| Na Hu, Huaiqiang Sun, Gui Fu, Wenjing Zhang, Yuan Xiao, Lianqing Zhang, Wenbin Li, Zhe Li, Guoping Huang, Youguo Tan, John A Sweeney, Qiyong Gong, Su Lu. Anatomic abnormalities of hippocampal subfields in never-treated and antipsychotic-treated patients with long-term schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 35. 2021-08-10. PMID:32402652. |
anatomic abnormalities of hippocampal subfields in never-treated and antipsychotic-treated patients with long-term schizophrenia. |
2021-08-10 |
2023-08-13 |
Not clear |
| Na Hu, Huaiqiang Sun, Gui Fu, Wenjing Zhang, Yuan Xiao, Lianqing Zhang, Wenbin Li, Zhe Li, Guoping Huang, Youguo Tan, John A Sweeney, Qiyong Gong, Su Lu. Anatomic abnormalities of hippocampal subfields in never-treated and antipsychotic-treated patients with long-term schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 35. 2021-08-10. PMID:32402652. |
hippocampal volume deficits have been reported in chronically-treated schizophrenia patients, however, the longer-term effects of antipsychotic medications on hippocampal anatomy are unclear. |
2021-08-10 |
2023-08-13 |
Not clear |
| Na Hu, Huaiqiang Sun, Gui Fu, Wenjing Zhang, Yuan Xiao, Lianqing Zhang, Wenbin Li, Zhe Li, Guoping Huang, Youguo Tan, John A Sweeney, Qiyong Gong, Su Lu. Anatomic abnormalities of hippocampal subfields in never-treated and antipsychotic-treated patients with long-term schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 35. 2021-08-10. PMID:32402652. |
this case-control study investigated volume differences in hippocampal subfields of never-treated and antipsychotic-treated patients with long-term schizophrenia. |
2021-08-10 |
2023-08-13 |
Not clear |
| Na Hu, Huaiqiang Sun, Gui Fu, Wenjing Zhang, Yuan Xiao, Lianqing Zhang, Wenbin Li, Zhe Li, Guoping Huang, Youguo Tan, John A Sweeney, Qiyong Gong, Su Lu. Anatomic abnormalities of hippocampal subfields in never-treated and antipsychotic-treated patients with long-term schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 35. 2021-08-10. PMID:32402652. |
findings indicate clinically-relevant and age-related volume reductions in hippocampal subfields of never-treated patients with long-term schizophrenia. |
2021-08-10 |
2023-08-13 |
Not clear |
| Junchao Huang, Yu Zhu, Fengmei Fan, Song Chen, Yuan Hong, Yimin Cui, Xingguang Luo, Shuping Tan, Zhiren Wang, Lan Shang, Ying Yuan, Jianxin Zhang, Fude Yang, Chiang-Shan R Li, Laura M Rowland, Peter Kochunov, Fengyu Zhang, L Elliot Hong, Yunlong Ta. Hippocampus and cognitive domain deficits in treatment-resistant schizophrenia: A comparison with matched treatment-responsive patients and healthy controls Psychiatry research. Neuroimaging. vol 297. 2021-08-06. PMID:32062167. |
hippocampus and cognitive domain deficits in treatment-resistant schizophrenia: a comparison with matched treatment-responsive patients and healthy controls some patients with schizophrenia do not respond to pharmacotherapy. |
2021-08-06 |
2023-08-13 |
Not clear |
| Junchao Huang, Yu Zhu, Fengmei Fan, Song Chen, Yuan Hong, Yimin Cui, Xingguang Luo, Shuping Tan, Zhiren Wang, Lan Shang, Ying Yuan, Jianxin Zhang, Fude Yang, Chiang-Shan R Li, Laura M Rowland, Peter Kochunov, Fengyu Zhang, L Elliot Hong, Yunlong Ta. Hippocampus and cognitive domain deficits in treatment-resistant schizophrenia: A comparison with matched treatment-responsive patients and healthy controls Psychiatry research. Neuroimaging. vol 297. 2021-08-06. PMID:32062167. |
the findings suggest that treatment-resistance to currently available antipsychotic medications may not be due to global cognitive deficits in these patients, but be associated with specific deficits in working memory and hippocampus deficits in the subgroup of schizophrenia. |
2021-08-06 |
2023-08-13 |
Not clear |
| b' El\\xc3\\xa7in \\xc3\\x96z\\xc3\\xa7elik Ero\\xc4\\x9flu, Ayg\\xc3\\xbcn Ertu\\xc4\\x9frul, Kader Karl\\xc4\\xb1 O\\xc4\\x9fuz, Sevilay Karahan, M K\\xc3\\xa2z\\xc4\\xb1m Yaz\\xc4\\xb1c\\xc4\\xb. Effect of Clozapine on Proton Magnetic Resonance Spectroscopy Findings in Hippocampus. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 31. issue 3. 2021-08-06. PMID:32978951.' |
the purpose of this study was to investigate the effect of clozapine on proton magnetic resonance spectroscopy (1h-mrs) findings in hippocampus in patients with schizophrenia. |
2021-08-06 |
2023-08-13 |
Not clear |
| Zhaowen Liu, Lena Palaniyappan, Xinran Wu, Kai Zhang, Jiangnan Du, Qi Zhao, Chao Xie, Yingying Tang, Wenjun Su, Yarui Wei, Kangkang Xue, Shaoqiang Han, Shih-Jen Tsai, Ching-Po Lin, Jingliang Cheng, Chunbo Li, Jijun Wang, Barbara J Sahakian, Trevor W Robbins, Jie Zhang, Jianfeng Fen. Resolving heterogeneity in schizophrenia through a novel systems approach to brain structure: individualized structural covariance network analysis. Molecular psychiatry. 2021-07-28. PMID:34316005. |
we conclude that the underlying physiology of affective symptoms in schizophrenia involves the hippocampus and putamen/pallidum, predates disease onset, and is sufficiently consistent to resolve morphological heterogeneity throughout the illness course. |
2021-07-28 |
2023-08-13 |
human |
| Hao Zhu, Yu Yang, Min Zhu, Xiao Shi, Le Ye, Song Zhang, Hongwei Fang, Wenjuan Y. Alteration in the expression of inflammatory cytokines in primary hippocampal astrocytes in response to MK-801 through ERK1/2 and PI3K signals. Cytokine. vol 138. 2021-07-26. PMID:33187817. |
these findings suggest that hippocampal astrocytes may regulate the expressions of inflammatory cytokines through erk1/2 and pi3k signaling pathway to participate in the pathogenesis of schizophrenia. |
2021-07-26 |
2023-08-13 |
rat |
| Sun-Young Moon, Minah Kim, Silvia Kyungjin Lho, Sanghoon Oh, Se Hyun Kim, Jun Soo Kwo. Systematic Review of the Neural Effect of Electroconvulsive Therapy in Patients with Schizophrenia: Hippocampus and Insula as the Key Regions of Modulation. Psychiatry investigation. vol 18. issue 6. 2021-07-20. PMID:34218638. |
systematic review of the neural effect of electroconvulsive therapy in patients with schizophrenia: hippocampus and insula as the key regions of modulation. |
2021-07-20 |
2023-08-13 |
Not clear |
| Zachary B Jones, Jiajing Zhang, Yuying Wu, Yi Zho. Inhibition of 14-3-3 Proteins Alters Neural Oscillations in Mice. Frontiers in neural circuits. vol 15. 2021-07-16. PMID:33776658. |
here we investigated how 14-3-3 inhibition alters neuronal network activity in the mouse hippocampus (hpc) and prefrontal cortex (pfc), key brain regions implicated in schizophrenia pathophysiology. |
2021-07-16 |
2023-08-13 |
mouse |
| Niels Haan, Laura J Westacott, Jenny Carter, Michael J Owen, William P Gray, Jeremy Hall, Lawrence S Wilkinso. Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms. Translational psychiatry. vol 11. issue 1. 2021-07-14. PMID:34031371. |
haploinsufficiency of the schizophrenia and autism risk gene cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and arp2/3 mediated actin dependent mechanisms. |
2021-07-14 |
2023-08-13 |
Not clear |
| Ileana Marinescu, Dragoş Marinescu, Laurenţiu Mogoantă, Ion Cristian Efrem, Puiu Olivian Stovice. SARS-CoV-2 infection in patients with serious mental illness and possible benefits of prophylaxis with Memantine and Amantadine. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 61. issue 4. 2021-07-07. PMID:34171050. |
activation of m1-type microglia has an important role in pathogenesis of major psychiatric disorders, such as major depression, schizophrenia or bipolar disorder, and may associate hippocampal atrophy and disconnection of cognitive structures. |
2021-07-07 |
2023-08-13 |
Not clear |
| F Scheffler, S Du Plessis, L Asmal, S Kilian, L Phahladira, H K Luckhoff, R Emsle. Cannabis use and hippocampal subfield volumes in males with a first episode of a schizophrenia spectrum disorder and healthy controls. Schizophrenia research. vol 231. 2021-07-05. PMID:33740561. |
the hippocampus is a region of particular interest due to its role in memory and select cognitive functions, impairment of which is a core feature of schizophrenia and has also been observed in substance abuse. |
2021-07-05 |
2023-08-13 |
Not clear |
| Shiral S Gangadin, Wiepke Cahn, Thomas W Scheewe, Hilleke E Hulshoff Pol, Matthijs G Bosson. Reduced resting state functional connectivity in the hippocampus-midbrain-striatum network of schizophrenia patients. Journal of psychiatric research. vol 138. 2021-07-05. PMID:33836433. |
contemporary preclinical models suggest that abnormal functioning of a brain network consisting of the hippocampus, midbrain and striatum plays a critical role in the pathophysiology of schizophrenia. |
2021-07-05 |
2023-08-13 |
human |
| Maria E Plataki, Konstantinos Diskos, Christos Sougklakos, Marouso Velissariou, Alexandros Georgilis, Vasiliki Stavroulaki, Kyriaki Sidiropoulo. Effect of Neonatal Treatment With the NMDA Receptor Antagonist, MK-801, During Different Temporal Windows of Postnatal Period in Adult Prefrontal Cortical and Hippocampal Function. Frontiers in behavioral neuroscience. vol 15. 2021-06-29. PMID:34177484. |
no differences were identified in the expression of nmda receptor subunits, the synapsin or psd-95 proteins, either in the prefrontal cortex (pfc) or the hippocampus (hpc), brain regions significantly affected in schizophrenia. |
2021-06-29 |
2023-08-13 |
mouse |