| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masataka Kikuchi, Takanobu Nakazawa, Makoto Kinoshita, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Ryota Hashimoto, Shusuke Numat. Methylation Analysis in Monozygotic Twins With Treatment-Resistant Schizophrenia and Discordant Responses to Clozapine. Frontiers in psychiatry. vol 12. 2021-10-08. PMID:34616320. |
clozapine, an atypical antipsychotic, is a well-established therapy for treatment-resistant schizophrenia. |
2021-10-08 |
2023-08-13 |
Not clear |
| Masataka Kikuchi, Takanobu Nakazawa, Makoto Kinoshita, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Ryota Hashimoto, Shusuke Numat. Methylation Analysis in Monozygotic Twins With Treatment-Resistant Schizophrenia and Discordant Responses to Clozapine. Frontiers in psychiatry. vol 12. 2021-10-08. PMID:34616320. |
in this study, we focused on a set of monozygotic twins with treatment-resistant schizophrenia in which one twin effectively responded to clozapine treatment and the other did not. |
2021-10-08 |
2023-08-13 |
Not clear |
| Masataka Kikuchi, Takanobu Nakazawa, Makoto Kinoshita, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Ryota Hashimoto, Shusuke Numat. Methylation Analysis in Monozygotic Twins With Treatment-Resistant Schizophrenia and Discordant Responses to Clozapine. Frontiers in psychiatry. vol 12. 2021-10-08. PMID:34616320. |
these results suggest that effective clozapine action may correct the abnormalities of neuronal and synapse functions in schizophrenia via changes in methylation. |
2021-10-08 |
2023-08-13 |
Not clear |
| Seon-Cheol Park, Bong Ju Lee, Jae Hong Park, Hiroaki Kawasaki, Ajit Avasthi, Sandeep Grover, Andi J Tanra, Shih-Ku Lin, Afzal Javed, Chay Hoon Tan, Norman Sartorius, Naotaka Shinfuku, Yong Chon Par. QT interval prolongation noted in one percent of 2553 Asian patients with schizophrenia: Findings from the REAP-AP survey. The Kaohsiung journal of medical sciences. vol 36. issue 12. 2021-10-07. PMID:32772489. |
schizophrenia patients were characterized by lower proportions of disorganized speech and negative symptoms; higher use of amisulpride and clozapine; and higher proportions of rigidity, hypercholesterolemia, and sedation than those without qtc prolongation. |
2021-10-07 |
2023-08-13 |
Not clear |
| Seon-Cheol Park, Bong Ju Lee, Jae Hong Park, Hiroaki Kawasaki, Ajit Avasthi, Sandeep Grover, Andi J Tanra, Shih-Ku Lin, Afzal Javed, Chay Hoon Tan, Norman Sartorius, Naotaka Shinfuku, Yong Chon Par. QT interval prolongation noted in one percent of 2553 Asian patients with schizophrenia: Findings from the REAP-AP survey. The Kaohsiung journal of medical sciences. vol 36. issue 12. 2021-10-07. PMID:32772489. |
finally, a binary logistic mode showed that amisulpride, clozapine, rigidity, and hypercholesterolemia might be the distinctive clinical correlates of qtc prolongation in asian patients with schizophrenia. |
2021-10-07 |
2023-08-13 |
Not clear |
| Seon-Cheol Park, Bong Ju Lee, Jae Hong Park, Hiroaki Kawasaki, Ajit Avasthi, Sandeep Grover, Andi J Tanra, Shih-Ku Lin, Afzal Javed, Chay Hoon Tan, Norman Sartorius, Naotaka Shinfuku, Yong Chon Par. QT interval prolongation noted in one percent of 2553 Asian patients with schizophrenia: Findings from the REAP-AP survey. The Kaohsiung journal of medical sciences. vol 36. issue 12. 2021-10-07. PMID:32772489. |
these findings indicate the clinical implications that the uses of amisulpride and clozapine and the occurrences of rigidity and hypercholesterolemia may be potential risk factors for qtc prolongation of schizophrenia patients. |
2021-10-07 |
2023-08-13 |
Not clear |
| Edouard-Jules Laforgue, Marion Istvan, Marylène Guerlais, Anicet Chaslerie, Pascal Artarit, Genevieve Vallot, Pascale Jolliet, Marie Grall-Bronnec, Caroline Victorri-Vignea. What about regular hematological monitoring during clozapine treatment? A compliance analysis using the French health insurance database. Expert opinion on drug safety. vol 20. issue 10. 2021-10-07. PMID:34085879. |
the aim of this study was to assess the compliance with wbcm during clozapine initiation for schizophrenia and parkinson's disease (pd) subjects. |
2021-10-07 |
2023-08-13 |
human |
| Francesco Monteleone, Márcia Gonçalves, Luís Fonseca, Sónia Simões, Andreia Gonçalves, Eduarda Machado, João Fonsec. Clozapine-Induced Eosinophilia: a Case Report. Revista Colombiana de psiquiatria (English ed.). 2021-10-07. PMID:34167790. |
clozapine is an atypical antipsychotic drug eligible for treatment-resistant schizophrenia. |
2021-10-07 |
2023-08-13 |
Not clear |
| Joshep Revilla-Zúñiga, Joise Cornejo-Del Carpio, Lizardo Cruzad. Hepatoxicity Induced by Clozapine: Case Report and Brief Review. Revista Colombiana de psiquiatria (English ed.). 2021-10-07. PMID:34167791. |
clozapine is an atypical antipsychotic used in treatment-resistant schizophrenia and there is evidence that it can produce elevations of hepatic transaminases, expression of liver damage in a hepatocellular pattern. |
2021-10-07 |
2023-08-13 |
Not clear |
| Dara Gammon, Catherine Cheng, Anna Volkovinskaia, Glen B Baker, Serdar M Dursu. Clozapine: Why Is It So Uniquely Effective in the Treatment of a Range of Neuropsychiatric Disorders? Biomolecules. vol 11. issue 7. 2021-10-06. PMID:34356654. |
clozapine is superior to other antipsychotics as a therapy for treatment-resistant schizophrenia and schizoaffective disorder with increased risk of suicidal behavior. |
2021-10-06 |
2023-08-13 |
Not clear |
| Ali Metehan Caliskan, Munir Karaaslan, Ikbal Inanli, Sila Caliskan, Mehmet Arslan, Ismet Esra Cicek, Ibrahim Ere. The effects of adding long-acting injectable antipsychotic drugs to clozapine on relapse and hospitalization in patients with treatment-resistant schizophrenia: a mirror-image retrospective study. International clinical psychopharmacology. vol 36. issue 1. 2021-10-04. PMID:33044315. |
the effects of adding long-acting injectable antipsychotic drugs to clozapine on relapse and hospitalization in patients with treatment-resistant schizophrenia: a mirror-image retrospective study. |
2021-10-04 |
2023-08-13 |
Not clear |
| Ali Metehan Caliskan, Munir Karaaslan, Ikbal Inanli, Sila Caliskan, Mehmet Arslan, Ismet Esra Cicek, Ibrahim Ere. The effects of adding long-acting injectable antipsychotic drugs to clozapine on relapse and hospitalization in patients with treatment-resistant schizophrenia: a mirror-image retrospective study. International clinical psychopharmacology. vol 36. issue 1. 2021-10-04. PMID:33044315. |
the aim of this retrospective study was to determine the safety and effectiveness of adding lais to clozapine in patients with treatment-resistant schizophrenia (trs). |
2021-10-04 |
2023-08-13 |
Not clear |
| Masaru Nakamura, Takahiko Nagamin. Prevalence and predictors of laxatives use in clozapine-related constipation: an observational study. International clinical psychopharmacology. vol 36. issue 3. 2021-10-04. PMID:33724255. |
this study aimed to investigate the prevalence of constipation and the breakdown of laxatives, and to identify whether use of laxative may be predicted by demographics or baseline metabolic markers in 53 japanese treatment-resistant schizophrenia inpatients switched to clozapine. |
2021-10-04 |
2023-08-13 |
human |
| Benedikt Munzar, Boris Nemet. Clinical Experience With Intramuscular Clozapine. Cureus. vol 13. issue 9. 2021-10-01. PMID:34589377. |
in summary, im clozapine may facilitate successful transition to oral clozapine in most patients, and it definitely represents a valuable tool for addressing refusal of oral clozapine in patients with treatment-refractory schizophrenia. |
2021-10-01 |
2023-08-13 |
Not clear |
| Petru Ifteni, Andreea Teodorescu, Lorena Dima, Victoria Burte. Rapid Titration of Clozapine in Schizophrenia and Bipolar Disorder. American journal of therapeutics. vol 28. issue 2. 2021-09-29. PMID:31567198. |
rapid titration of clozapine in schizophrenia and bipolar disorder. |
2021-09-29 |
2023-08-13 |
Not clear |
| Petru Ifteni, Andreea Teodorescu, Lorena Dima, Victoria Burte. Rapid Titration of Clozapine in Schizophrenia and Bipolar Disorder. American journal of therapeutics. vol 28. issue 2. 2021-09-29. PMID:31567198. |
the rapid clozapine titration was introduced in our hospital in the early 2000's as "last resort" method for aggressive, belligerent or homicidal patients with schizophrenia and bipolar disorder. |
2021-09-29 |
2023-08-13 |
Not clear |
| Petru Ifteni, Andreea Teodorescu, Lorena Dima, Victoria Burte. Rapid Titration of Clozapine in Schizophrenia and Bipolar Disorder. American journal of therapeutics. vol 28. issue 2. 2021-09-29. PMID:31567198. |
as there are no randomized controlled clinical trials to compare the efficacy and safety of standard versus rapid titration of clozapine in schizophrenia or bipolar disorder, future studies are needed. |
2021-09-29 |
2023-08-13 |
Not clear |
| Kenya A Costa-Dookhan, Tarek K Rajji, Veronica N Tran, Sylvie Bowden, Daniel J Mueller, Gary J Remington, Sri Mahavir Agarwal, Margaret K Hah. Associations between plasma clozapine/N-desmethylclozapine ratio, insulin resistance and cognitive performance in patients with co-morbid obesity and ultra-treatment resistant schizophrenia. Scientific reports. vol 11. issue 1. 2021-09-27. PMID:33479273. |
clozapine (clz), the sole antipsychotic with superior efficacy for ultra-treatment resistant schizophrenia (trs), is limited by adverse effects, including metabolic dysregulation. |
2021-09-27 |
2023-08-13 |
Not clear |
| Graham Blackman, Ebenezer Oloyed. Clozapine discontinuation withdrawal symptoms in schizophrenia. Therapeutic advances in psychopharmacology. vol 11. 2021-09-25. PMID:34552710. |
clozapine discontinuation withdrawal symptoms in schizophrenia. |
2021-09-25 |
2023-08-13 |
Not clear |
| Graham Blackman, Ebenezer Oloyed. Clozapine discontinuation withdrawal symptoms in schizophrenia. Therapeutic advances in psychopharmacology. vol 11. 2021-09-25. PMID:34552710. |
clozapine is an atypical antipsychotic used in treatment-resistant schizophrenia. |
2021-09-25 |
2023-08-13 |
Not clear |