| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joshep Revilla-Zúñiga, Joise Cornejo-Del Carpio, Lizardo Cruzad. Hepatoxicity Induced by Clozapine: Case Report and Brief Review. Revista Colombiana de psiquiatria (English ed.). 2021-10-07. PMID:34167791. |
clozapine is an atypical antipsychotic used in treatment-resistant schizophrenia and there is evidence that it can produce elevations of hepatic transaminases, expression of liver damage in a hepatocellular pattern. |
2021-10-07 |
2023-08-13 |
Not clear |
| Dara Gammon, Catherine Cheng, Anna Volkovinskaia, Glen B Baker, Serdar M Dursu. Clozapine: Why Is It So Uniquely Effective in the Treatment of a Range of Neuropsychiatric Disorders? Biomolecules. vol 11. issue 7. 2021-10-06. PMID:34356654. |
clozapine is superior to other antipsychotics as a therapy for treatment-resistant schizophrenia and schizoaffective disorder with increased risk of suicidal behavior. |
2021-10-06 |
2023-08-13 |
Not clear |
| Ali Metehan Caliskan, Munir Karaaslan, Ikbal Inanli, Sila Caliskan, Mehmet Arslan, Ismet Esra Cicek, Ibrahim Ere. The effects of adding long-acting injectable antipsychotic drugs to clozapine on relapse and hospitalization in patients with treatment-resistant schizophrenia: a mirror-image retrospective study. International clinical psychopharmacology. vol 36. issue 1. 2021-10-04. PMID:33044315. |
the effects of adding long-acting injectable antipsychotic drugs to clozapine on relapse and hospitalization in patients with treatment-resistant schizophrenia: a mirror-image retrospective study. |
2021-10-04 |
2023-08-13 |
Not clear |
| Ali Metehan Caliskan, Munir Karaaslan, Ikbal Inanli, Sila Caliskan, Mehmet Arslan, Ismet Esra Cicek, Ibrahim Ere. The effects of adding long-acting injectable antipsychotic drugs to clozapine on relapse and hospitalization in patients with treatment-resistant schizophrenia: a mirror-image retrospective study. International clinical psychopharmacology. vol 36. issue 1. 2021-10-04. PMID:33044315. |
the aim of this retrospective study was to determine the safety and effectiveness of adding lais to clozapine in patients with treatment-resistant schizophrenia (trs). |
2021-10-04 |
2023-08-13 |
Not clear |
| Masaru Nakamura, Takahiko Nagamin. Prevalence and predictors of laxatives use in clozapine-related constipation: an observational study. International clinical psychopharmacology. vol 36. issue 3. 2021-10-04. PMID:33724255. |
this study aimed to investigate the prevalence of constipation and the breakdown of laxatives, and to identify whether use of laxative may be predicted by demographics or baseline metabolic markers in 53 japanese treatment-resistant schizophrenia inpatients switched to clozapine. |
2021-10-04 |
2023-08-13 |
human |
| Benedikt Munzar, Boris Nemet. Clinical Experience With Intramuscular Clozapine. Cureus. vol 13. issue 9. 2021-10-01. PMID:34589377. |
in summary, im clozapine may facilitate successful transition to oral clozapine in most patients, and it definitely represents a valuable tool for addressing refusal of oral clozapine in patients with treatment-refractory schizophrenia. |
2021-10-01 |
2023-08-13 |
Not clear |
| Petru Ifteni, Andreea Teodorescu, Lorena Dima, Victoria Burte. Rapid Titration of Clozapine in Schizophrenia and Bipolar Disorder. American journal of therapeutics. vol 28. issue 2. 2021-09-29. PMID:31567198. |
rapid titration of clozapine in schizophrenia and bipolar disorder. |
2021-09-29 |
2023-08-13 |
Not clear |
| Petru Ifteni, Andreea Teodorescu, Lorena Dima, Victoria Burte. Rapid Titration of Clozapine in Schizophrenia and Bipolar Disorder. American journal of therapeutics. vol 28. issue 2. 2021-09-29. PMID:31567198. |
the rapid clozapine titration was introduced in our hospital in the early 2000's as "last resort" method for aggressive, belligerent or homicidal patients with schizophrenia and bipolar disorder. |
2021-09-29 |
2023-08-13 |
Not clear |
| Petru Ifteni, Andreea Teodorescu, Lorena Dima, Victoria Burte. Rapid Titration of Clozapine in Schizophrenia and Bipolar Disorder. American journal of therapeutics. vol 28. issue 2. 2021-09-29. PMID:31567198. |
as there are no randomized controlled clinical trials to compare the efficacy and safety of standard versus rapid titration of clozapine in schizophrenia or bipolar disorder, future studies are needed. |
2021-09-29 |
2023-08-13 |
Not clear |
| Kenya A Costa-Dookhan, Tarek K Rajji, Veronica N Tran, Sylvie Bowden, Daniel J Mueller, Gary J Remington, Sri Mahavir Agarwal, Margaret K Hah. Associations between plasma clozapine/N-desmethylclozapine ratio, insulin resistance and cognitive performance in patients with co-morbid obesity and ultra-treatment resistant schizophrenia. Scientific reports. vol 11. issue 1. 2021-09-27. PMID:33479273. |
clozapine (clz), the sole antipsychotic with superior efficacy for ultra-treatment resistant schizophrenia (trs), is limited by adverse effects, including metabolic dysregulation. |
2021-09-27 |
2023-08-13 |
Not clear |
| Graham Blackman, Ebenezer Oloyed. Clozapine discontinuation withdrawal symptoms in schizophrenia. Therapeutic advances in psychopharmacology. vol 11. 2021-09-25. PMID:34552710. |
clozapine discontinuation withdrawal symptoms in schizophrenia. |
2021-09-25 |
2023-08-13 |
Not clear |
| Graham Blackman, Ebenezer Oloyed. Clozapine discontinuation withdrawal symptoms in schizophrenia. Therapeutic advances in psychopharmacology. vol 11. 2021-09-25. PMID:34552710. |
clozapine is an atypical antipsychotic used in treatment-resistant schizophrenia. |
2021-09-25 |
2023-08-13 |
Not clear |
| J W Y Yuen, C Wu, C K Wang, D D Kim, R M Procyshyn, W G Honer, A M Bar. A comparison of the effects of clozapine and its metabolite norclozapine on metabolic dysregulation in rodent models. Neuropharmacology. vol 175. 2021-09-23. PMID:31348941. |
the second generation antipsychotic drug clozapine is a psychotherapeutic agent with superior efficacy for treatment-resistant schizophrenia. |
2021-09-23 |
2023-08-13 |
Not clear |
| Sharon Taub, Moshe Hoshen, Ran Balicer, Shiri Kamhi-Nesher, Abraham Weizman, Amir Krivo. Metabolic predictors for mortality among patients treated with long-term clozapine - A longitudinal study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 41. 2021-09-23. PMID:32981820. |
in this study we aimed to explore predictors for mortality in a large cohort of schizophrenia patients treated with long-term clozapine, using the electronic medical records of the largest health care provider in israel. |
2021-09-23 |
2023-08-13 |
Not clear |
| John Lally, Emily Breese, Mugtaba Osman, Cai Hua Sim, Hitesh Shetty, Amir Krivoy, James H MacCab. Augmentation of clozapine with ECT: a retrospective case analysis. Acta neuropsychiatrica. vol 33. issue 1. 2021-09-20. PMID:32967745. |
we sought to assess the effectiveness of clozapine augmentation with electroconvulsive therapy (ect) (c+ect) in patients with clozapine-resistant schizophrenia. |
2021-09-20 |
2023-08-13 |
Not clear |
| Yumiko Akamine, Yuka Kikuchi, Masatomo Miur. Effects on monotherapy and reduction of antipsychotic drugs by clozapine therapy in Japanese patients with treatment-resistant schizophrenia. Journal of clinical pharmacy and therapeutics. vol 46. issue 5. 2021-09-16. PMID:33959995. |
effects on monotherapy and reduction of antipsychotic drugs by clozapine therapy in japanese patients with treatment-resistant schizophrenia. |
2021-09-16 |
2023-08-13 |
Not clear |
| Yumiko Akamine, Yuka Kikuchi, Masatomo Miur. Effects on monotherapy and reduction of antipsychotic drugs by clozapine therapy in Japanese patients with treatment-resistant schizophrenia. Journal of clinical pharmacy and therapeutics. vol 46. issue 5. 2021-09-16. PMID:33959995. |
the schizophrenia guidelines in japan and many other countries describe clozapine as the first-choice drug for patients with treatment-resistant schizophrenia. |
2021-09-16 |
2023-08-13 |
Not clear |
| Elisa Pallares Vela, Prashil Dave, Ivan Cancarevi. Clozapine-Related Thromboembolic Events. Cureus. vol 13. issue 8. 2021-09-14. PMID:34513458. |
clozapine is an atypical antipsychotic used for treatment-resistant schizophrenia. |
2021-09-14 |
2023-08-13 |
Not clear |
| Subho Chakrabart. Clozapine resistant schizophrenia: Newer avenues of management. World journal of psychiatry. vol 11. issue 8. 2021-09-14. PMID:34513606. |
clozapine resistant schizophrenia: newer avenues of management. |
2021-09-14 |
2023-08-13 |
Not clear |
| Subho Chakrabart. Clozapine resistant schizophrenia: Newer avenues of management. World journal of psychiatry. vol 11. issue 8. 2021-09-14. PMID:34513606. |
about 40%-70% of the patients with treatment-resistant schizophrenia have a poor response to adequate treatment with clozapine. |
2021-09-14 |
2023-08-13 |
Not clear |