| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Young Tak Jo, Sung Woo Joo, Soojin Ahn, Youngjae Choi, Jungsun Le. Use of olanzapine compared with clozapine for treatment-resistant schizophrenia in a real-world setting: nationwide register-based study. BJPsych open. vol 7. issue 5. 2021-08-21. PMID:34342261. |
clozapine is generally considered as the treatment of choice for patients with treatment-resistant schizophrenia (trs). |
2021-08-21 |
2023-08-13 |
Not clear |
| Julie R Larsen, Camilla K Svensson, Louise Vedtofte, Mathilde Lund Jakobsen, Hans Søe Jespersen, Michelle I Jakobsen, Kamuran Koyuncu, Ole Schjerning, Jimmi Nielsen, Claus T Ekstrøm, Jens J Holst, Christoph U Correll, Tina Vilsbøll, Anders Fink-Jense. High prevalence of prediabetes and metabolic abnormalities in overweight or obese schizophrenia patients treated with clozapine or olanzapine. CNS spectrums. vol 24. issue 4. 2021-08-20. PMID:30596361. |
high prevalence of prediabetes and metabolic abnormalities in overweight or obese schizophrenia patients treated with clozapine or olanzapine. |
2021-08-20 |
2023-08-13 |
Not clear |
| Giulia Tronchin, Genevieve McPhilemy, Mohamed Ahmed, Liam Kilmartin, Laura Costello, Natalie J Forde, Leila Nabulsi, Theophilus N Akudjedu, Laurena Holleran, Brian Hallahan, Dara M Cannon, Colm McDonal. White matter microstructure and structural networks in treatment-resistant schizophrenia patients after commencing clozapine treatment: A longitudinal diffusion imaging study. Psychiatry research. vol 298. 2021-08-19. PMID:33556689. |
white matter microstructure and structural networks in treatment-resistant schizophrenia patients after commencing clozapine treatment: a longitudinal diffusion imaging study. |
2021-08-19 |
2023-08-13 |
Not clear |
| Giulia Tronchin, Genevieve McPhilemy, Mohamed Ahmed, Liam Kilmartin, Laura Costello, Natalie J Forde, Leila Nabulsi, Theophilus N Akudjedu, Laurena Holleran, Brian Hallahan, Dara M Cannon, Colm McDonal. White matter microstructure and structural networks in treatment-resistant schizophrenia patients after commencing clozapine treatment: A longitudinal diffusion imaging study. Psychiatry research. vol 298. 2021-08-19. PMID:33556689. |
this study investigates changes on white matter microstructure and neural networks after 6 months of switching to clozapine in schizophrenia patients compared to controls, and whether any changes are related to clinical variables. |
2021-08-19 |
2023-08-13 |
Not clear |
| Giulia Tronchin, Genevieve McPhilemy, Mohamed Ahmed, Liam Kilmartin, Laura Costello, Natalie J Forde, Leila Nabulsi, Theophilus N Akudjedu, Laurena Holleran, Brian Hallahan, Dara M Cannon, Colm McDonal. White matter microstructure and structural networks in treatment-resistant schizophrenia patients after commencing clozapine treatment: A longitudinal diffusion imaging study. Psychiatry research. vol 298. 2021-08-19. PMID:33556689. |
t1 and diffusion-weighted mri images were acquired at baseline before commencing clozapine and after 6 months of treatment for 22 patients with treatment-resistant schizophrenia and 23 controls. |
2021-08-19 |
2023-08-13 |
Not clear |
| Katsunori Toyoda, Takeo Hata, Shigeru Yamauchi, Shinya Kinoshita, Masami Nishihara, Kazuhisa Uchiyama, Ken Inada, Tetsufumi Kanazaw. A descriptive study of 10-year clozapine use from the nationwide database in Japan. Psychiatry research. vol 297. 2021-08-19. PMID:33567393. |
this survey was conducted to identify the actual usage of clozapine and changes required to increase the number of patients with schizophrenia who would benefit from clozapine. |
2021-08-19 |
2023-08-13 |
human |
| Tiffany Buckley, Christopher Kitchen, Gopal Vyas, Nathan A Siegfried, Eshetu Tefera, Shuo Chen, Bethany A DiPaula, Deanna L Kell. Comparison of Novel Immunoassay With Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) for Therapeutic Drug Monitoring of Clozapine. Therapeutic drug monitoring. vol 42. issue 5. 2021-08-18. PMID:32569062. |
clozapine is the most effective antipsychotic for treatment-resistant schizophrenia. |
2021-08-18 |
2023-08-13 |
Not clear |
| Mustafa Cicek, William V McCall, Zhixing Yao, Harold A Sackeim, Peter Rosenquist, Nagy A Yousse. Is There Evidence That Stimulus Parameters and Electrode Placement Affect the Cognitive Side Effects of Electroconvulsive Therapy in Patients With Schizophrenia and Schizoaffective Disorder?: A Systematic Review. The journal of ECT. vol 37. issue 2. 2021-08-18. PMID:33369995. |
seventy percent of patients with treatment-resistant schizophrenia do not respond to clozapine. |
2021-08-18 |
2023-08-13 |
Not clear |
| Eromona Whiskey, Alex Barnard, Ebenezer Oloyede, Olubanke Dzahini, David M Taylor, Sukhwinder S Shergil. An evaluation of the variation and underuse of clozapine in the United Kingdom. Acta psychiatrica Scandinavica. vol 143. issue 4. 2021-08-18. PMID:33501659. |
clozapine is the only licensed treatment for treatment refractory schizophrenia. |
2021-08-18 |
2023-08-13 |
Not clear |
| Elias Wagner, Tatiana Oviedo-Salcedo, Nicola Pelzer, Wolfgang Strube, Isabel Maurus, Stefan Gutwinski, Stefanie Schreiter, Phillip Kleymann, Carla-Lou Morgenroth, Cynthia Okhuijsen-Pfeifer, Jurjen J Luykx, Peter Falkai, Thomas Schneider-Axmann, Alkomiet Hasa. Effects of Smoking Status on Remission and Metabolic and Cognitive Outcomes in Schizophrenia Patients Treated with Clozapine. Pharmacopsychiatry. vol 53. issue 6. 2021-08-13. PMID:32757178. |
effects of smoking status on remission and metabolic and cognitive outcomes in schizophrenia patients treated with clozapine. |
2021-08-13 |
2023-08-13 |
Not clear |
| Xiding Yang, Qiangyong Yan, Lingfeng Yang, Jingjing Li, Xiao Fan, Jindong Chen, Haishan Wu, Hualin Cai, Ronghua Zhu, Pingfei Fan. Evaluation of bioequivalence between generic and brand-name clozapine in Chinese schizophrenic patients: A randomized, two-period, crossover study. International journal of clinical pharmacology and therapeutics. vol 59. issue 8. 2021-08-11. PMID:34142950. |
clozapine is the most effective therapy for schizophrenia. |
2021-08-11 |
2023-08-13 |
Not clear |
| Francesco Dal Santo, Isaac Jarratt-Barnham, Leticia González-Blanco, María Paz García-Portilla, Julio Bobes, Emilio Fernández-Ege. Longitudinal effects of clozapine concentration and clozapine to N-desmethylclozapine ratio on cognition: A mediation model. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 33. 2021-08-10. PMID:32057590. |
previous cross-sectional studies have found clozapine to n-desmethylclozapine (clz:ndmc) ratio to be negatively correlated with cognition in clozapine-treated patients with schizophrenia. |
2021-08-10 |
2023-08-13 |
Not clear |
| Emily Rose, Shanquan Chen, Concha Turrion, Christopher Jenkins, Rudolf N Cardinal, Emilio Fernandez-Ege. Causes of death in clozapine-treated patients in a catchment area: a 10-year retrospective case-control study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 36. 2021-08-10. PMID:32546415. |
here, we aimed to assess a decade of causes of deaths in a catchment area in patients with schizophrenia chronically treated with clozapine and compared them to a clozapine-treated control cohort. |
2021-08-10 |
2023-08-13 |
Not clear |
| Mikiko Ishibashi, Kentaro Matsui, Masahiko Kawano, Hidehiro Oshibuchi, Jun Ishigooka, Katsuji Nishimura, Ken Inad. Clinical Factors Associated with New-Onset Glucose Intolerance among Patients with Schizophrenia during Clozapine Treatment: All-Case Surveillance in Japan. The Tohoku journal of experimental medicine. vol 252. issue 2. 2021-08-09. PMID:33055431. |
clinical factors associated with new-onset glucose intolerance among patients with schizophrenia during clozapine treatment: all-case surveillance in japan. |
2021-08-09 |
2023-08-13 |
Not clear |
| Mikiko Ishibashi, Kentaro Matsui, Masahiko Kawano, Hidehiro Oshibuchi, Jun Ishigooka, Katsuji Nishimura, Ken Inad. Clinical Factors Associated with New-Onset Glucose Intolerance among Patients with Schizophrenia during Clozapine Treatment: All-Case Surveillance in Japan. The Tohoku journal of experimental medicine. vol 252. issue 2. 2021-08-09. PMID:33055431. |
clozapine (clz), an antipsychotic with a unique mechanism of action, is known to be superior to any other antipsychotic for schizophrenia. |
2021-08-09 |
2023-08-13 |
Not clear |
| b' El\\xc3\\xa7in \\xc3\\x96z\\xc3\\xa7elik Ero\\xc4\\x9flu, Ayg\\xc3\\xbcn Ertu\\xc4\\x9frul, Kader Karl\\xc4\\xb1 O\\xc4\\x9fuz, Sevilay Karahan, M K\\xc3\\xa2z\\xc4\\xb1m Yaz\\xc4\\xb1c\\xc4\\xb. Effect of Clozapine on Proton Magnetic Resonance Spectroscopy Findings in Hippocampus. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 31. issue 3. 2021-08-06. PMID:32978951.' |
the purpose of this study was to investigate the effect of clozapine on proton magnetic resonance spectroscopy (1h-mrs) findings in hippocampus in patients with schizophrenia. |
2021-08-06 |
2023-08-13 |
Not clear |
| Ibrahim A Akkouh, Hana Hribkova, Marta Grabiec, Eva Budinska, Attila Szabo, Tomas Kasparek, Ole A Andreassen, Yuh-Man Sun, Srdjan Djurovi. Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response. Schizophrenia bulletin. 2021-08-06. PMID:34357384. |
derivation and molecular characterization of a morphological subpopulation of human ipsc astrocytes reveal a potential role in schizophrenia and clozapine response. |
2021-08-06 |
2023-08-13 |
human |
| Ibrahim A Akkouh, Hana Hribkova, Marta Grabiec, Eva Budinska, Attila Szabo, Tomas Kasparek, Ole A Andreassen, Yuh-Man Sun, Srdjan Djurovi. Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response. Schizophrenia bulletin. 2021-08-06. PMID:34357384. |
we further found reduced levels of both glutamate and the nmda receptor coagonist d-serine in subtype astrocytes derived from schizophrenia patients, and that exposure to clozapine only rescued this deficiency in cells from clozapine responders, providing further evidence that d-serine in particular, and nmda receptor-mediated glutamatergic neurotransmission in general, could play an important role in disease pathophysiology and clozapine action. |
2021-08-06 |
2023-08-13 |
human |
| Theodore R Zarzar, Joseph B Williams, Megan E Pruette, Brian B Sheitma. A Legal Right to Clozapine Therapy for Incarcerated Individuals With Treatment-Resistant Schizophrenia. Psychiatric services (Washington, D.C.). vol 72. issue 4. 2021-08-03. PMID:33593106. |
a legal right to clozapine therapy for incarcerated individuals with treatment-resistant schizophrenia. |
2021-08-03 |
2023-08-13 |
Not clear |
| Theodore R Zarzar, Joseph B Williams, Megan E Pruette, Brian B Sheitma. A Legal Right to Clozapine Therapy for Incarcerated Individuals With Treatment-Resistant Schizophrenia. Psychiatric services (Washington, D.C.). vol 72. issue 4. 2021-08-03. PMID:33593106. |
however, incarcerated patients with treatment-resistant schizophrenia (trs) often are not offered clozapine, the only medication for this debilitating illness approved by the u.s. food and drug administration. |
2021-08-03 |
2023-08-13 |
Not clear |