| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Y. [The correlation between clozapine saliva level and clinical response as well as side effect in patient with schizophrenia]. Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry. vol 25. issue 3. 1992-11-04. PMID:1356717. |
it was measured for clozapine saliva level in 62 patients with schizophrenia taking clozapine, the study have found that therapeutic window was at the range from 550 ng/ml to 920 ng/ml in 34 patients with duration more than two years and was at the range from 400 ng/ml to 510 ng/ml in 28 patients with duration less than two years. |
1992-11-04 |
2023-08-11 |
Not clear |
| U Osby, A Durlin. [Clozapine treatment of schizophrenia caused eosinophilia]. Lakartidningen. vol 89. issue 26-27. 1992-09-22. PMID:1507947. |
[clozapine treatment of schizophrenia caused eosinophilia]. |
1992-09-22 |
2023-08-11 |
Not clear |
| L S Pilowsky, D C Costa, P J Ell, R M Murray, N P Verhoeff, R W Kerwi. Clozapine, single photon emission tomography, and the D2 dopamine receptor blockade hypothesis of schizophrenia. Lancet (London, England). vol 340. issue 8813. 1992-08-21. PMID:1353135. |
clozapine, single photon emission tomography, and the d2 dopamine receptor blockade hypothesis of schizophrenia. |
1992-08-21 |
2023-08-11 |
Not clear |
| M S Buchsbaum, S G Potkin, J F Marshall, S Lottenberg, C Teng, C W Heh, R Tafalla, C Reynolds, L Abel, L Plo. Effects of clozapine and thiothixene on glucose metabolic rate in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 6. issue 3. 1992-07-10. PMID:1599606. |
effects of clozapine and thiothixene on glucose metabolic rate in schizophrenia. |
1992-07-10 |
2023-08-11 |
human |
| M S Buchsbaum, S G Potkin, J F Marshall, S Lottenberg, C Teng, C W Heh, R Tafalla, C Reynolds, L Abel, L Plo. Effects of clozapine and thiothixene on glucose metabolic rate in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 6. issue 3. 1992-07-10. PMID:1599606. |
twelve patients with schizophrenia received positron emission tomography scans with 18f-deoxyglucose before and after 4 to 6 weeks of treatment with clozapine or thiothixene. |
1992-07-10 |
2023-08-11 |
human |
| E H Friedman, G G Sander. Clozapine and cortical metabolism in schizophrenia. Biological psychiatry. vol 31. issue 5. 1992-06-18. PMID:1581431. |
clozapine and cortical metabolism in schizophrenia. |
1992-06-18 |
2023-08-11 |
Not clear |
| H Y Meltzer, G A Gudelsk. Dopaminergic and serotonergic effects of clozapine. Implications for a unique clinical profile. Arzneimittel-Forschung. vol 42. issue 2A. 1992-06-16. PMID:1586397. |
the clinical profile of clozapine (cas 5786-21-0) is characterized by superior efficacy in reducing the positive and negative symptoms of schizophrenia and a greatly reduced propensity to elicit acute extrapyramidal symptoms (e.g., parkinsonian symptoms), long-term effects (e.g., tardive dyskinesia) and hyperprolactinemia. |
1992-06-16 |
2023-08-11 |
Not clear |
| D Pickar, R R Owen, R E Litman, E Konicki, R Gutierrez, M H Rapapor. Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine. Archives of general psychiatry. vol 49. issue 5. 1992-06-15. PMID:1375019. |
clinical and biologic response to clozapine in patients with schizophrenia. |
1992-06-15 |
2023-08-11 |
Not clear |
| D Pickar, R R Owen, R E Litman, E Konicki, R Gutierrez, M H Rapapor. Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine. Archives of general psychiatry. vol 49. issue 5. 1992-06-15. PMID:1375019. |
twenty-one patients with schizophrenia who met criteria for neuroleptic treatment resistance or intolerance participated in a crossover, placebo-controlled, double-blind comparison of long-term typical neuroleptic and clozapine treatment. |
1992-06-15 |
2023-08-11 |
Not clear |
| L Friedman, J A Jesberger, H Y Meltze. Effect of typical antipsychotic medications and clozapine on smooth pursuit performance in patients with schizophrenia. Psychiatry research. vol 41. issue 1. 1992-05-11. PMID:1348583. |
effect of typical antipsychotic medications and clozapine on smooth pursuit performance in patients with schizophrenia. |
1992-05-11 |
2023-08-11 |
human |
| L Friedman, J A Jesberger, H Y Meltze. Effect of typical antipsychotic medications and clozapine on smooth pursuit performance in patients with schizophrenia. Psychiatry research. vol 41. issue 1. 1992-05-11. PMID:1348583. |
the effect of typical neuroleptic drugs or clozapine on smooth pursuit eye movements was tested in 13 patients with schizophrenia or schizoaffective disorder with a repeated measures design. |
1992-05-11 |
2023-08-11 |
human |
| G S Robertson, H C Fibige. Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine. Neuroscience. vol 46. issue 2. 1992-04-08. PMID:1347406. |
the mechanisms by which the atypical neuroleptic clozapine produces its therapeutic effects in the treatment of schizophrenia without causing the extrapyramidal side effects that are characteristic of most antipsychotic drugs remain unclear. |
1992-04-08 |
2023-08-11 |
Not clear |
| R F Squires, E Saederu. A review of evidence for GABergic predominance/glutamatergic deficit as a common etiological factor in both schizophrenia and affective psychoses: more support for a continuum hypothesis of "functional" psychosis. Neurochemical research. vol 16. issue 10. 1992-04-08. PMID:1686635. |
virtually all antidepressant and antipsychotic drugs, including clozapine, rimcazole and lithium ion, are proconvulsants, and convulsive therapy, using metrazol, a known gaba-a antagonist, as well as electro-convulsive therapy, can be effective in treating both schizophrenia and affective psychoses. |
1992-04-08 |
2023-08-11 |
Not clear |
| B Birmaher, R Baker, S Kapur, H Quintana, R Gangul. Clozapine for the treatment of adolescents with schizophrenia. Journal of the American Academy of Child and Adolescent Psychiatry. vol 31. issue 1. 1992-04-01. PMID:1537770. |
clozapine for the treatment of adolescents with schizophrenia. |
1992-04-01 |
2023-08-11 |
Not clear |
| B Birmaher, R Baker, S Kapur, H Quintana, R Gangul. Clozapine for the treatment of adolescents with schizophrenia. Journal of the American Academy of Child and Adolescent Psychiatry. vol 31. issue 1. 1992-04-01. PMID:1537770. |
despite recent reports that clozapine is useful for the treatment of chronic schizophrenics resistant to neuroleptics, no studies have been reported in adolescents with schizophrenia. |
1992-04-01 |
2023-08-11 |
Not clear |
| B Birmaher, R Baker, S Kapur, H Quintana, R Gangul. Clozapine for the treatment of adolescents with schizophrenia. Journal of the American Academy of Child and Adolescent Psychiatry. vol 31. issue 1. 1992-04-01. PMID:1537770. |
the authors report three successful trials of clozapine in adolescents with schizophrenia who did not respond to conventional neuroleptic treatment. |
1992-04-01 |
2023-08-11 |
Not clear |
| L Garmendia, J R Sánchez, A Azpiroz, P F Brain, V M Simó. Clozapine: strong antiaggressive effects with minimal motor impairment. Physiology & behavior. vol 51. issue 1. 1992-03-23. PMID:1741450. |
clinical studies have shown clozapine to be effective in the treatment of schizophrenia and associated with an extremely low incidence of extrapiramidal side effects. |
1992-03-23 |
2023-08-11 |
mouse |
| S L McElroy, E C Dessain, H G Pope, J O Cole, P E Keck, F R Frankenberg, H G Aizley, S O'Brie. Clozapine in the treatment of psychotic mood disorders, schizoaffective disorder, and schizophrenia. The Journal of clinical psychiatry. vol 52. issue 10. 1991-12-16. PMID:1938976. |
clozapine in the treatment of psychotic mood disorders, schizoaffective disorder, and schizophrenia. |
1991-12-16 |
2023-08-11 |
Not clear |
| Clozapine and loxapine for schizophrenia. Drug and therapeutics bulletin. vol 29. issue 11. 1991-12-02. PMID:1747161. |
clozapine and loxapine for schizophrenia. |
1991-12-02 |
2023-08-11 |
Not clear |
| b' V Kor\\xc3\\xadnkov\\xc3\\xa1, V Novotn\\xc3\\xb. [Maintenance therapy in schizophrenia using clozapine]. Ceskoslovenska psychiatrie. vol 87. issue 2. 1991-10-30. PMID:1913953.' |
[maintenance therapy in schizophrenia using clozapine]. |
1991-10-30 |
2023-08-11 |
Not clear |