| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Y Meltzer, M A Lee, R Ranja. Recent advances in the pharmacotherapy of schizophrenia. Acta psychiatrica Scandinavica. Supplementum. vol 384. 1995-03-31. PMID:7533472. |
the major advance in the psychopharmacology of schizophrenia has been the rediscovery of clozapine and the development of other novel antipsychotic drugs, all of which are superior to typical neuroleptic drugs with regard to extrapyramidal symptoms. |
1995-03-31 |
2023-08-12 |
Not clear |
| b' P Zvolsk\\xc3\\xbd, J Hul\\xc3\\xadnsk\\xc3\\xb. [Clozapine--an atypical antipsychotic agents, its advantages and risks]. Ceskoslovenska psychiatrie. vol 90. issue 6. 1995-03-23. PMID:7859323.' |
despite the cost of treatment and checks of the haemogram, clozapine reduces the sum total of expenditure associated with the treatment of chronic schizophrenia by reducing the number of re-admissions to hospital, by shortening the period of hospitalization and by cutting indirect costs, which are influenced by a greater sociability of the patient and a greater probability of successful comprehensive therapeutic procedures. |
1995-03-23 |
2023-08-12 |
Not clear |
| M L Rao, H J Mölle. Biochemical findings of negative symptoms in schizophrenia and their putative relevance to pharmacologic treatment. A review. Neuropsychobiology. vol 30. issue 4. 1995-03-22. PMID:7862264. |
however, negative symptoms of schizophrenia that occur independently of positive symptoms may also be reduced with monoamine oxidase inhibitors and atypical antipsychotic drugs, such as clozapine. |
1995-03-22 |
2023-08-12 |
Not clear |
| G Chouinard, J L Vainer, M C Bélanger, L Turnier, P Beaudry, J Y Roy, R Mille. Risperidone and clozapine in the treatment of drug-resistant schizophrenia and neuroleptic-induced supersensitivity psychosis. Progress in neuro-psychopharmacology & biological psychiatry. vol 18. issue 7. 1995-03-07. PMID:7531355. |
risperidone and clozapine in the treatment of drug-resistant schizophrenia and neuroleptic-induced supersensitivity psychosis. |
1995-03-07 |
2023-08-12 |
Not clear |
| H Y Meltzer, G Okayl. Reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia: impact on risk-benefit assessment. The American journal of psychiatry. vol 152. issue 2. 1995-03-01. PMID:7840350. |
reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia: impact on risk-benefit assessment. |
1995-03-01 |
2023-08-12 |
Not clear |
| R S Kahn, L Siever, M Davidson, C Greenwald, C Moor. Haloperidol and clozapine treatment and their effect on M-chlorophenylpiperazine-mediated responses in schizophrenia: implications for the mechanism of action of clozapine. Psychopharmacology. vol 112. issue 1 Suppl. 1995-02-22. PMID:7831445. |
haloperidol and clozapine treatment and their effect on m-chlorophenylpiperazine-mediated responses in schizophrenia: implications for the mechanism of action of clozapine. |
1995-02-22 |
2023-08-12 |
Not clear |
| H Y Meltzer, M Maes, M A Le. The cimetidine-induced increase in prolactin secretion in schizophrenia: effect of clozapine. Psychopharmacology. vol 112. issue 1 Suppl. 1995-02-22. PMID:7831446. |
the cimetidine-induced increase in prolactin secretion in schizophrenia: effect of clozapine. |
1995-02-22 |
2023-08-12 |
Not clear |
| H Y Meltzer, M Maes, M A Le. The cimetidine-induced increase in prolactin secretion in schizophrenia: effect of clozapine. Psychopharmacology. vol 112. issue 1 Suppl. 1995-02-22. PMID:7831446. |
there is considerable interest in the role of serotonin (5-ht) in the pathophysiology of schizophrenia and in the mechanism of action of clozapine, an atypical antipsychotic agent and a potent dopamine (da), 5-ht2/5-ht1c and histamine (h) antagonist. |
1995-02-22 |
2023-08-12 |
Not clear |
| S Gupta, P Bake. Clozapine treatment of polydipsia. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 6. issue 2. 1995-01-30. PMID:7804389. |
a patient with refractory chronic schizophrenia having severe polydipsia and hyponatremia was treated with clozapine. |
1995-01-30 |
2023-08-12 |
Not clear |
| T P Zahn, D Pickar, R J Haie. Effects of clozapine, fluphenazine, and placebo on reaction time measures of attention and sensory dominance in schizophrenia. Schizophrenia research. vol 13. issue 2. 1995-01-09. PMID:7986770. |
effects of clozapine, fluphenazine, and placebo on reaction time measures of attention and sensory dominance in schizophrenia. |
1995-01-09 |
2023-08-12 |
human |
| S A Cohen, M T Underwoo. The use of clozapine in a mentally retarded and aggressive population. The Journal of clinical psychiatry. vol 55. issue 10. 1994-12-23. PMID:7961521. |
clozapine has proven efficacy in the management of treatment-resistant schizophrenia. |
1994-12-23 |
2023-08-12 |
Not clear |
| J A Lieberman, A Z Safferman, S Pollack, S Szymanski, C Johns, A Howard, M Kronig, P Bookstein, J M Kan. Clinical effects of clozapine in chronic schizophrenia: response to treatment and predictors of outcome. The American journal of psychiatry. vol 151. issue 12. 1994-12-20. PMID:7977880. |
clinical effects of clozapine in chronic schizophrenia: response to treatment and predictors of outcome. |
1994-12-20 |
2023-08-12 |
Not clear |
| R G Stern, R S Kahn, M Davidson, R M Nora, K L Davi. Early response to clozapine in schizophrenia. The American journal of psychiatry. vol 151. issue 12. 1994-12-20. PMID:7977893. |
early response to clozapine in schizophrenia. |
1994-12-20 |
2023-08-12 |
Not clear |
| J Welch, T Manschreck, D Redmon. Clozapine-induced seizures and EEG changes. The Journal of neuropsychiatry and clinical neurosciences. vol 6. issue 3. 1994-12-05. PMID:7950347. |
clozapine, an atypical antipsychotic drug, is widely used in refractory schizophrenia. |
1994-12-05 |
2023-08-12 |
Not clear |
| Y Levkowitz, Y Kronnenberg, N Kaysar, H Harari, B Gaon. [Clozapine in adolescence onset schizophrenia]. Harefuah. vol 127. issue 1-2. 1994-12-02. PMID:7959380. |
[clozapine in adolescence onset schizophrenia]. |
1994-12-02 |
2023-08-12 |
Not clear |
| Y Levkowitz, Y Kronnenberg, N Kaysar, H Harari, B Gaon. [Clozapine in adolescence onset schizophrenia]. Harefuah. vol 127. issue 1-2. 1994-12-02. PMID:7959380. |
clozapine is an atypical neuroleptic agent given when schizophrenia is resistant to other neuroleptic drugs. |
1994-12-02 |
2023-08-12 |
Not clear |
| Y Levkowitz, Y Kronnenberg, N Kaysar, H Harari, B Gaon. [Clozapine in adolescence onset schizophrenia]. Harefuah. vol 127. issue 1-2. 1994-12-02. PMID:7959380. |
in our opinion, clozapine should be considered when severe schizophrenia in adolescents is refractory to other neuroleptic agents, provided the wbc count is monitored. |
1994-12-02 |
2023-08-12 |
Not clear |
| D Pickar, R R Owen, R E Litman, J K Hsiao, T P S. Predictors of clozapine response in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7525541. |
predictors of clozapine response in schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| D Pickar, R R Owen, R E Litman, J K Hsiao, T P S. Predictors of clozapine response in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7525541. |
the introduction of the atypical neuroleptic, clozapine, has had widespread influence not only on the treatment of the seriously mentally ill patient, but also on new drug development and on hypotheses of the pathophysiology of schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| D Pickar, R R Owen, R E Litman, J K Hsiao, T P S. Predictors of clozapine response in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7525541. |
further, our data suggest that clozapine should not be reserved for the most chronically ill patients, but rather be utilized in patients with less chronic courses of schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |