| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R M Bilder, H Wu, M H Chakos, B Bogerts, S Pollack, J Aronowitz, M Ashtari, G Degreef, J M Kane, J A Lieberma. Cerebral morphometry and clozapine treatment in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961574. |
this paper reviews findings from magnetic resonance imaging studies of patients with schizophrenia conducted at hillside hospital, with special attention to (1) findings that have helped distinguish patients who respond well to typical neuroleptics from those who have gone on to trials of clozapine, (2) the capacity of morphological measures to predict clozapine treatment response, and (3) the possibility that selective hypertrophy of striatal structure may be caused by chronic treatment with typical neuroleptics, but not by clozapine. |
1994-11-28 |
2023-08-12 |
Not clear |
| S G Potkin, M S Buchsbaum, Y Jin, C Tang, J Telford, G Friedman, S Lottenberg, A Najafi, B Gulasekaram, J Cost. Clozapine effects on glucose metabolic rate in striatum and frontal cortex. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961576. |
eighteen patients with schizophrenia had cerebral metabolic rates assessed with positron emission tomography during a double-blind, placebo-controlled crossover study of clozapine treatment. |
1994-11-28 |
2023-08-12 |
Not clear |
| S G Potkin, M S Buchsbaum, Y Jin, C Tang, J Telford, G Friedman, S Lottenberg, A Najafi, B Gulasekaram, J Cost. Clozapine effects on glucose metabolic rate in striatum and frontal cortex. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961576. |
we have previously observed patients with schizophrenia to have low metabolic rates in the basal ganglia and to lack the normal right > left asymmetry; in this study, clozapine normalized striatal activity. |
1994-11-28 |
2023-08-12 |
Not clear |
| M A Lee, P A Thompson, H Y Meltze. Effects of clozapine on cognitive function in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961582. |
effects of clozapine on cognitive function in schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| M A Lee, P A Thompson, H Y Meltze. Effects of clozapine on cognitive function in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961582. |
we have studied the effect of clozapine, an atypical antipsychotic drug, on cognitive function in 36 patients with treatment-resistant schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| M A Lee, P A Thompson, H Y Meltze. Effects of clozapine on cognitive function in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961582. |
in addition, patients with non-treatment-resistant schizophrenia were randomly assigned to clozapine (n = 24) or typical neuroleptics (n = 23). |
1994-11-28 |
2023-08-12 |
Not clear |
| M A Lee, P A Thompson, H Y Meltze. Effects of clozapine on cognitive function in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961582. |
clozapine treatment improved several domains of cognitive function, especially attention and verbal fluency in both treatment-resistant schizophrenia and non-treatment-resistant schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| M A Lee, P A Thompson, H Y Meltze. Effects of clozapine on cognitive function in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961582. |
the effect of clozapine on some tests of attention and verbal fluency was significantly greater than that of typical neuroleptic treatment in non-treatment-resistant schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| M A Lee, P A Thompson, H Y Meltze. Effects of clozapine on cognitive function in schizophrenia. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961582. |
these data suggest that clozapine treatment was superior to typical neuroleptics in improving cognitive function in schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| S E Kimmel, J R Calabrese, M J Woyshville, H Y Meltze. Clozapine in treatment-refractory mood disorders. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961583. |
these preliminary data as well as the clinical reports reviewed indicate that the efficacy of clozapine in treatment-resistant patients is not limited to patients with schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| S C Piscitelli, J A Frazier, K McKenna, K E Albus, D R Grothe, C T Gordon, J L Rapopor. Plasma clozapine and haloperidol concentrations in adolescents with childhood-onset schizophrenia: association with response. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961584. |
plasma clozapine and haloperidol concentrations in adolescents with childhood-onset schizophrenia: association with response. |
1994-11-28 |
2023-08-12 |
Not clear |
| S C Piscitelli, J A Frazier, K McKenna, K E Albus, D R Grothe, C T Gordon, J L Rapopor. Plasma clozapine and haloperidol concentrations in adolescents with childhood-onset schizophrenia: association with response. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961584. |
plasma clozapine and haloperidol concentrations were studied in adolescents being treated for childhood-onset schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| A Z Safferman, J M Kane, J S Aronowitz, M F Gordon, S Pollack, J A Lieberma. The use of clozapine in neurologic disorders. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961585. |
the advent of clozapine has marked a major advance in the treatment of schizophrenia because of its low incidence of extrapyramidal side effects and superior efficacy. |
1994-11-28 |
2023-08-12 |
Not clear |
| A Z Safferman, J M Kane, J S Aronowitz, M F Gordon, S Pollack, J A Lieberma. The use of clozapine in neurologic disorders. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961585. |
in general, clozapine doses used in these settings are lower than that for treating psychosis in schizophrenia. |
1994-11-28 |
2023-08-12 |
Not clear |
| B A Malow, K B Reese, S Sato, P J Bogard, A K Malhotra, T P Su, D Picka. Spectrum of EEG abnormalities during clozapine treatment. Electroencephalography and clinical neurophysiology. vol 91. issue 3. 1994-10-20. PMID:7522149. |
clozapine is a novel antipsychotic agent effective in treating refractory schizophrenia. |
1994-10-20 |
2023-08-12 |
Not clear |
| D Marinkovic, I Timotijevic, T Babinski, S Totic, V R Paunovi. The side-effects of clozapine: a four year follow-up study. Progress in neuro-psychopharmacology & biological psychiatry. vol 18. issue 3. 1994-10-06. PMID:8078987. |
clozapine, as the model agent for the atypical antipsychotic drugs, is currently recommended as effective regarding negative symptoms of schizophrenia and treatment-resistant schizophrenic patients. |
1994-10-06 |
2023-08-12 |
Not clear |
| M Maes, H Y Meltzer, E Bosman. Immune-inflammatory markers in schizophrenia: comparison to normal controls and effects of clozapine. Acta psychiatrica Scandinavica. vol 89. issue 5. 1994-09-22. PMID:8067274. |
immune-inflammatory markers in schizophrenia: comparison to normal controls and effects of clozapine. |
1994-09-22 |
2023-08-12 |
human |
| M Maes, H Y Meltzer, E Bosman. Immune-inflammatory markers in schizophrenia: comparison to normal controls and effects of clozapine. Acta psychiatrica Scandinavica. vol 89. issue 5. 1994-09-22. PMID:8067274. |
the purpose of this study was to investigate immune-inflammatory markers in schizophrenia and the effects of chronic treatment with clozapine, an atypical antipsychotic agent, on these variables. |
1994-09-22 |
2023-08-12 |
human |
| M Maes, H Y Meltzer, E Bosman. Immune-inflammatory markers in schizophrenia: comparison to normal controls and effects of clozapine. Acta psychiatrica Scandinavica. vol 89. issue 5. 1994-09-22. PMID:8067274. |
we conclude that: (a) schizophrenia in younger people is accompanied by increased il-6 and sil-2r secretion; and (b) subchronic treatment with clozapine increases sil-2r levels. |
1994-09-22 |
2023-08-12 |
human |
| H Mok, L N Yatha. Response to clozapine as a predictor of risperidone response in schizophrenia. The American journal of psychiatry. vol 151. issue 9. 1994-09-16. PMID:7520672. |
response to clozapine as a predictor of risperidone response in schizophrenia. |
1994-09-16 |
2023-08-12 |
Not clear |