| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Laune. Clozapine in schizophrenia. Lancet (London, England). vol 345. issue 8962. 1995-06-29. PMID:7605499. |
clozapine in schizophrenia. |
1995-06-29 |
2023-08-12 |
Not clear |
| W T Carpenter, R R Conley, R W Buchanan, A Breier, C A Tamming. Patient response and resource management: another view of clozapine treatment of schizophrenia. The American journal of psychiatry. vol 152. issue 6. 1995-06-21. PMID:7755110. |
patient response and resource management: another view of clozapine treatment of schizophrenia. |
1995-06-21 |
2023-08-12 |
Not clear |
| J B Sebens, T Koch, G J Ter Horst, J Kor. Differential Fos-protein induction in rat forebrain regions after acute and long-term haloperidol and clozapine treatment. European journal of pharmacology. vol 273. issue 1-2. 1995-06-05. PMID:7737311. |
the persisting effect of clozapine in the nucleus accumbens may be of significance to the efficacy of this drug in treatment-refractory schizophrenia. |
1995-06-05 |
2023-08-12 |
rat |
| E Klieser, E Lehmann, E Kinzler, C Wurthmann, K Heinric. Randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7537287. |
randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia. |
1995-05-31 |
2023-08-12 |
Not clear |
| E Klieser, E Lehmann, E Kinzler, C Wurthmann, K Heinric. Randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7537287. |
this study compares the antipsychotic efficacy and the tolerability of risperidone and clozapine in patients with schizophrenia. |
1995-05-31 |
2023-08-12 |
Not clear |
| E Klieser, E Lehmann, E Kinzler, C Wurthmann, K Heinric. Randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7537287. |
the results suggest that risperidone is at least as effective as an antipsychotic as clozapine, providing a valuable new approach for the treatment of schizophrenia. |
1995-05-31 |
2023-08-12 |
Not clear |
| M Huttune. The evolution of the serotonin-dopamine antagonist concept. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7730499. |
suggestions that serotonin might be involved in the cause of schizophrenia or could be a target for antipsychotic drug action began with the discovery that the antipsychotic agent clozapine is a potent serotonin 5-ht2a antagonist, as well as being a dopamine d2 antagonist. |
1995-05-31 |
2023-08-12 |
Not clear |
| R W Kerwi. Clozapine: back to the future for schizophrenia research. Lancet (London, England). vol 345. issue 8957. 1995-05-16. PMID:7715333. |
clozapine: back to the future for schizophrenia research. |
1995-05-16 |
2023-08-12 |
Not clear |
| S Szymanski, J Lieberman, S Pollack, A Safferman, R Munne, D Umbricht, J Kane, M Kronig, M Chakos, T Coope. Clozapine effects on neuroendocrine response to apomorphine challenge testing in chronic neuroleptic nonresponsive schizophrenia: preliminary findings. Biological psychiatry. vol 37. issue 1. 1995-04-25. PMID:7893860. |
clozapine effects on neuroendocrine response to apomorphine challenge testing in chronic neuroleptic nonresponsive schizophrenia: preliminary findings. |
1995-04-25 |
2023-08-12 |
Not clear |
| C Bryoi. [New psychopharmacologic alternatives in treatment of schizophrenia]. Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985). vol 145. issue 6. 1995-04-12. PMID:7533941. |
clozapine, risperidone and remoxipride are three neuroleptics that represent an interesting alternative in the psychopharmacological treatment of schizophrenia. |
1995-04-12 |
2023-08-12 |
Not clear |
| I Jalenques, A J Couder. [Clozapine and refractory schizophrenia. Long-term prospective study of 20 patients]. L'Encephale. vol 20. issue 6. 1995-04-04. PMID:7875111. |
[clozapine and refractory schizophrenia. |
1995-04-04 |
2023-08-12 |
Not clear |
| H Y Meltzer, M A Lee, R Ranja. Recent advances in the pharmacotherapy of schizophrenia. Acta psychiatrica Scandinavica. Supplementum. vol 384. 1995-03-31. PMID:7533472. |
the major advance in the psychopharmacology of schizophrenia has been the rediscovery of clozapine and the development of other novel antipsychotic drugs, all of which are superior to typical neuroleptic drugs with regard to extrapyramidal symptoms. |
1995-03-31 |
2023-08-12 |
Not clear |
| b' P Zvolsk\\xc3\\xbd, J Hul\\xc3\\xadnsk\\xc3\\xb. [Clozapine--an atypical antipsychotic agents, its advantages and risks]. Ceskoslovenska psychiatrie. vol 90. issue 6. 1995-03-23. PMID:7859323.' |
despite the cost of treatment and checks of the haemogram, clozapine reduces the sum total of expenditure associated with the treatment of chronic schizophrenia by reducing the number of re-admissions to hospital, by shortening the period of hospitalization and by cutting indirect costs, which are influenced by a greater sociability of the patient and a greater probability of successful comprehensive therapeutic procedures. |
1995-03-23 |
2023-08-12 |
Not clear |
| M L Rao, H J Mölle. Biochemical findings of negative symptoms in schizophrenia and their putative relevance to pharmacologic treatment. A review. Neuropsychobiology. vol 30. issue 4. 1995-03-22. PMID:7862264. |
however, negative symptoms of schizophrenia that occur independently of positive symptoms may also be reduced with monoamine oxidase inhibitors and atypical antipsychotic drugs, such as clozapine. |
1995-03-22 |
2023-08-12 |
Not clear |
| G Chouinard, J L Vainer, M C Bélanger, L Turnier, P Beaudry, J Y Roy, R Mille. Risperidone and clozapine in the treatment of drug-resistant schizophrenia and neuroleptic-induced supersensitivity psychosis. Progress in neuro-psychopharmacology & biological psychiatry. vol 18. issue 7. 1995-03-07. PMID:7531355. |
risperidone and clozapine in the treatment of drug-resistant schizophrenia and neuroleptic-induced supersensitivity psychosis. |
1995-03-07 |
2023-08-12 |
Not clear |
| H Y Meltzer, G Okayl. Reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia: impact on risk-benefit assessment. The American journal of psychiatry. vol 152. issue 2. 1995-03-01. PMID:7840350. |
reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia: impact on risk-benefit assessment. |
1995-03-01 |
2023-08-12 |
Not clear |
| R S Kahn, L Siever, M Davidson, C Greenwald, C Moor. Haloperidol and clozapine treatment and their effect on M-chlorophenylpiperazine-mediated responses in schizophrenia: implications for the mechanism of action of clozapine. Psychopharmacology. vol 112. issue 1 Suppl. 1995-02-22. PMID:7831445. |
haloperidol and clozapine treatment and their effect on m-chlorophenylpiperazine-mediated responses in schizophrenia: implications for the mechanism of action of clozapine. |
1995-02-22 |
2023-08-12 |
Not clear |
| H Y Meltzer, M Maes, M A Le. The cimetidine-induced increase in prolactin secretion in schizophrenia: effect of clozapine. Psychopharmacology. vol 112. issue 1 Suppl. 1995-02-22. PMID:7831446. |
the cimetidine-induced increase in prolactin secretion in schizophrenia: effect of clozapine. |
1995-02-22 |
2023-08-12 |
Not clear |
| H Y Meltzer, M Maes, M A Le. The cimetidine-induced increase in prolactin secretion in schizophrenia: effect of clozapine. Psychopharmacology. vol 112. issue 1 Suppl. 1995-02-22. PMID:7831446. |
there is considerable interest in the role of serotonin (5-ht) in the pathophysiology of schizophrenia and in the mechanism of action of clozapine, an atypical antipsychotic agent and a potent dopamine (da), 5-ht2/5-ht1c and histamine (h) antagonist. |
1995-02-22 |
2023-08-12 |
Not clear |
| S Gupta, P Bake. Clozapine treatment of polydipsia. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 6. issue 2. 1995-01-30. PMID:7804389. |
a patient with refractory chronic schizophrenia having severe polydipsia and hyponatremia was treated with clozapine. |
1995-01-30 |
2023-08-12 |
Not clear |