| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M S Kramer, B Last, A Getson, S A Reine. The effects of a selective D4 dopamine receptor antagonist (L-745,870) in acutely psychotic inpatients with schizophrenia. D4 Dopamine Antagonist Group. Archives of general psychiatry. vol 54. issue 6. 1997-06-27. PMID:9193198. |
based mainly on the selective antagonism of clozapine at d4 compared with d2 dopamine receptors, hopes have run high that a selective d4 dopamine receptor antagonist might improve the pharmacological treatment of patients with schizophrenia. |
1997-06-27 |
2023-08-12 |
Not clear |
| T H MacEwan, M J Morto. Use of clozapine in a child with treatment-resistant schizophrenia. The British journal of psychiatry : the journal of mental science. vol 168. issue 3. 1997-05-30. PMID:8833696. |
use of clozapine in a child with treatment-resistant schizophrenia. |
1997-05-30 |
2023-08-12 |
Not clear |
| T H MacEwan, M J Morto. Use of clozapine in a child with treatment-resistant schizophrenia. The British journal of psychiatry : the journal of mental science. vol 168. issue 3. 1997-05-30. PMID:8833696. |
clozapine is used effectively in adults with treatment-resistant schizophrenia but little is published on the use of clozapine in children. |
1997-05-30 |
2023-08-12 |
Not clear |
| M A Laune. Long-term treatment with clozapine in schizophrenia. The British journal of psychiatry : the journal of mental science. vol 168. issue 3. 1997-05-30. PMID:8833701. |
long-term treatment with clozapine in schizophrenia. |
1997-05-30 |
2023-08-12 |
Not clear |
| B Macfarlane, S Davies, K Mannan, R Sarsam, D Pariente, J Doole. Fatal acute fulminant liver failure due to clozapine: a case report and review of clozapine-induced hepatotoxicity. Gastroenterology. vol 112. issue 5. 1997-05-27. PMID:9136851. |
this report describes fatal acute fulminant liver failure caused by clozapine in a 39-year-old man with chronic paranoid schizophrenia. |
1997-05-27 |
2023-08-12 |
Not clear |
| G Joffe, E Venäläinen, J Tupala, O Hiltunen, K Wahlbeck, R Gädeke, R Rimo. The effect of clozapine on the course of illness in chronic schizophrenia: focus on treatment outcome in out-patients. International clinical psychopharmacology. vol 11. issue 4. 1997-05-22. PMID:9031993. |
the effect of clozapine on the course of illness in chronic schizophrenia: focus on treatment outcome in out-patients. |
1997-05-22 |
2023-08-12 |
Not clear |
| G Joffe, E Venäläinen, J Tupala, O Hiltunen, K Wahlbeck, R Gädeke, R Rimo. The effect of clozapine on the course of illness in chronic schizophrenia: focus on treatment outcome in out-patients. International clinical psychopharmacology. vol 11. issue 4. 1997-05-22. PMID:9031993. |
there appears to be a subgroup of hebephrenic patients who benefit from clozapine more than patients with other types of schizophrenia. |
1997-05-22 |
2023-08-12 |
Not clear |
| J Rabinowitz, M Avnon, V Rosenber. Effect of clozapine on physical and verbal aggression. Schizophrenia research. vol 22. issue 3. 1997-05-19. PMID:9000322. |
the hypothesis that clozapine reduced serious physically and verbally aggressive behavior of persons with schizophrenia whose symptoms did not respond to typical neuroleptic treatment was tested. |
1997-05-19 |
2023-08-12 |
Not clear |
| D J Freeman, L K Oyewum. Will routine therapeutic drug monitoring have a place in clozapine therapy? Clinical pharmacokinetics. vol 32. issue 2. 1997-05-13. PMID:9068925. |
clozapine is an atypical antipsychotic medication with proven efficacy in the management of refractory schizophrenia. |
1997-05-13 |
2023-08-12 |
Not clear |
| D J Still, P G Dorson, M L Crismon, C Pousso. Effects of switching inpatients with treatment-resistant schizophrenia from clozapine to risperidone. Psychiatric services (Washington, D.C.). vol 47. issue 12. 1997-04-23. PMID:9117479. |
effects of switching inpatients with treatment-resistant schizophrenia from clozapine to risperidone. |
1997-04-23 |
2023-08-12 |
Not clear |
| D J Still, P G Dorson, M L Crismon, C Pousso. Effects of switching inpatients with treatment-resistant schizophrenia from clozapine to risperidone. Psychiatric services (Washington, D.C.). vol 47. issue 12. 1997-04-23. PMID:9117479. |
a prospective, open-label study in a 400-bed state psychiatric hospital evaluated change in therapeutic response among ten patients with treatment-resistant schizophrenia who were switched from clozapine to risperidone. |
1997-04-23 |
2023-08-12 |
Not clear |
| D J Still, P G Dorson, M L Crismon, C Pousso. Effects of switching inpatients with treatment-resistant schizophrenia from clozapine to risperidone. Psychiatric services (Washington, D.C.). vol 47. issue 12. 1997-04-23. PMID:9117479. |
the findings do not support replacing clozapine with risperidone for patients with treatment-resistant schizophrenia. |
1997-04-23 |
2023-08-12 |
Not clear |
| G E Davis, W E Lowell, G L Davi. Measuring quality of care in a psychiatric hospital using artificial neural networks. American journal of medical quality : the official journal of the American College of Medical Quality. vol 12. issue 1. 1997-04-18. PMID:9116530. |
the study took place during hospital downsizing (political change), a consent decree (policy change), new administrative and medical personnel (staffing change), and the introduction of clozapine and risperidone for schizophrenia (therapeutic change). |
1997-04-18 |
2023-08-12 |
Not clear |
| P Odou, B Frimat, B Fontaine, M Luyckx, C Brunet, H Robert, T Dine, B Gressier, M Cazin, J C Cazi. Determination of clozapine in serum by radioreceptor assay versus high-performance liquid chromatography: possible detection of hydroxy-metabolites. Journal of clinical pharmacy and therapeutics. vol 21. issue 5. 1997-04-18. PMID:9119916. |
clozapine is an antipsychotic drug with few extra-pyramidal motor side-effects, used to treat schizophrenia which is resistant to classical neuroleptic therapy. |
1997-04-18 |
2023-08-12 |
Not clear |
| b' H L\\xc3\\xb4o, J P Oli\\xc3\\xa. [Clozapine and schizophrenias: 1991-1996]. L\'Encephale. vol 22 Spec No 6. 1997-04-17. PMID:9102312.' |
[clozapine and schizophrenias: 1991-1996]. |
1997-04-17 |
2023-08-12 |
Not clear |
| J M Kan. [Clozapine in the treatment of schizophrenia]. L'Encephale. vol 22 Spec No 6. 1997-04-17. PMID:9102320. |
[clozapine in the treatment of schizophrenia]. |
1997-04-17 |
2023-08-12 |
Not clear |
| J K Patel, C Salzman, A I Green, M T Tsuan. Chronic schizophrenia: response to clozapine, risperidone, and paroxetine. The American journal of psychiatry. vol 154. issue 4. 1997-04-16. PMID:9090343. |
chronic schizophrenia: response to clozapine, risperidone, and paroxetine. |
1997-04-16 |
2023-08-12 |
Not clear |
| J R Stevens, D Denney, P Szo. Kindling with clozapine: behavioral and molecular consequences. Epilepsy research. vol 26. issue 1. 1997-04-14. PMID:8985708. |
clozapine is an 'atypical' neuroleptic that improves symptoms of many patients with schizophrenia whose illness is resistant to treatment with other neuroleptics. |
1997-04-14 |
2023-08-12 |
rat |
| J R Stevens, D Denney, P Szo. Kindling with clozapine: behavioral and molecular consequences. Epilepsy research. vol 26. issue 1. 1997-04-14. PMID:8985708. |
the evidence of central nervous system excitation with clozapine may be important to the unique therapeutic effect of this atypical antipsychotic in the treatment of symptoms, especially the deficit symptoms, of schizophrenia. |
1997-04-14 |
2023-08-12 |
rat |
| A G Awad, L N Voruganti, R J Heslegrav. Measuring quality of life in patients with schizophrenia. PharmacoEconomics. vol 11. issue 1. 1997-04-11. PMID:10172917. |
however, pharmacoeconomic studies have attracted much interest as a result of the high cost of newly introduced medications and of concern about the limitations of antipsychotic medications, particularly their adverse effects, as exemplified by the reintroduction of clozapine for the treatment of refractory schizophrenia. |
1997-04-11 |
2023-08-12 |
Not clear |