| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R W Buchanan, A Breier, B Kirkpatrick, P Ball, W T Carpente. Positive and negative symptom response to clozapine in schizophrenic patients with and without the deficit syndrome. The American journal of psychiatry. vol 155. issue 6. 1998-06-18. PMID:9619146. |
in a preliminary report, the authors observed that clozapine was superior to haloperidol in the treatment of positive and negative symptoms in stable outpatients with schizophrenia. |
1998-06-18 |
2023-08-12 |
Not clear |
| H Jones, V A Curtis, P Wright, J V Luce. Neuroendocrine evidence that clozapine's serotonergic antagonism is relevant to its efficacy in treating hallucinations and other positive schizophrenic symptoms. The American journal of psychiatry. vol 155. issue 6. 1998-06-18. PMID:9619161. |
the authors examined the effect of prolonged clozapine treatment on central serotonergic (5-ht) function in schizophrenia. |
1998-06-18 |
2023-08-12 |
Not clear |
| L Lahdelma, A Ahokas, L C Andersson, M Huttunen, S Sarna, S Koskimie. Association between HLA-A1 allele and schizophrenia gene(s) in patients refractory to conventional neuroleptics but responsive to clozapine medication. Tissue antigens. vol 51. issue 2. 1998-06-01. PMID:9510376. |
association between hla-a1 allele and schizophrenia gene(s) in patients refractory to conventional neuroleptics but responsive to clozapine medication. |
1998-06-01 |
2023-08-12 |
Not clear |
| J I Tracy, C A Monaco, G Abraham, R C Josiassen, B G Polloc. Relation of serum anticholinergicity to cognitive status in schizophrenia patients taking clozapine or risperidone. The Journal of clinical psychiatry. vol 59. issue 4. 1998-05-29. PMID:9590669. |
relation of serum anticholinergicity to cognitive status in schizophrenia patients taking clozapine or risperidone. |
1998-05-29 |
2023-08-12 |
Not clear |
| J I Tracy, C A Monaco, G Abraham, R C Josiassen, B G Polloc. Relation of serum anticholinergicity to cognitive status in schizophrenia patients taking clozapine or risperidone. The Journal of clinical psychiatry. vol 59. issue 4. 1998-05-29. PMID:9590669. |
this study examines anticholinergic burden in schizophrenia patients taking clozapine and risperidone and tests whether this burden is associated with cognitive deficits. |
1998-05-29 |
2023-08-12 |
Not clear |
| W H Reid, M Maso. Psychiatric hospital utilization in patients treated with clozapine for up to 4.5 years in a state mental health care system. The Journal of clinical psychiatry. vol 59. issue 4. 1998-05-29. PMID:9590670. |
we wished to study long-term psychiatric hospital utilization in a large sample of patients with schizophrenia and/or schizoaffective disorders who were treated with clozapine for up to 4.5 years, and to determine whether or not the reduction in hospital utilization we previously observed in smaller groups for up to 2.5 years was sustained with larger groups and in the longer term. |
1998-05-29 |
2023-08-12 |
Not clear |
| G Ginsberg, S Shani, B Le. Cost-benefit analysis of risperidone and clozapine in the treatment of schizophrenia in Israel. PharmacoEconomics. vol 13. issue 2. 1998-05-28. PMID:10178649. |
cost-benefit analysis of risperidone and clozapine in the treatment of schizophrenia in israel. |
1998-05-28 |
2023-08-12 |
Not clear |
| G Ginsberg, S Shani, B Le. Cost-benefit analysis of risperidone and clozapine in the treatment of schizophrenia in Israel. PharmacoEconomics. vol 13. issue 2. 1998-05-28. PMID:10178649. |
in this study, the benefits and costs of treating schizophrenia with either risperidone or clozapine were examined. |
1998-05-28 |
2023-08-12 |
Not clear |
| G Ginsberg, S Shani, B Le. Cost-benefit analysis of risperidone and clozapine in the treatment of schizophrenia in Israel. PharmacoEconomics. vol 13. issue 2. 1998-05-28. PMID:10178649. |
the lifetime drug-treatment cost incurred by a patient with schizophrenia in israel was $us7561 (1996 values) with an initial 6-month trial with risperidone, compared with $us6326 with clozapine and $us3360 with typical antipsychotics. |
1998-05-28 |
2023-08-12 |
Not clear |
| S W Flynn, G W MacEwan, S Altman, L C Kopala, D H Fredrikson, G N Smith, W G Hone. An open comparison of clozapine and risperidone in treatment-resistant schizophrenia. Pharmacopsychiatry. vol 31. issue 1. 1998-05-21. PMID:9524981. |
an open comparison of clozapine and risperidone in treatment-resistant schizophrenia. |
1998-05-21 |
2023-08-12 |
Not clear |
| S W Flynn, G W MacEwan, S Altman, L C Kopala, D H Fredrikson, G N Smith, W G Hone. An open comparison of clozapine and risperidone in treatment-resistant schizophrenia. Pharmacopsychiatry. vol 31. issue 1. 1998-05-21. PMID:9524981. |
clozapine and risperidone are used in treatment-resistant schizophrenia. |
1998-05-21 |
2023-08-12 |
Not clear |
| R Ganguli, J S Bra. The effects of risperidone and olanzapine on the indications for clozapine. Psychopharmacology bulletin. vol 34. issue 1. 1998-05-21. PMID:9564203. |
the effects of the availability of risperidone and olanzapine on the indications for which clozapine is prescribed (treatment-resistance, treatment-intolerance, and/or negative symptoms) were examined for 252 patients with schizophrenia who began treatment at our hospital between june 1990 and june 1997. |
1998-05-21 |
2023-08-12 |
Not clear |
| S Pollack, M G Woerner, A Howard, R B Fireworker, J M Kan. Clozapine reduces rehospitalization among schizophrenia patients. Psychopharmacology bulletin. vol 34. issue 1. 1998-05-21. PMID:9564204. |
clozapine reduces rehospitalization among schizophrenia patients. |
1998-05-21 |
2023-08-12 |
Not clear |
| S Pollack, M G Woerner, A Howard, R B Fireworker, J M Kan. Clozapine reduces rehospitalization among schizophrenia patients. Psychopharmacology bulletin. vol 34. issue 1. 1998-05-21. PMID:9564204. |
the sample consisted of 81 schizophrenia patients who entered hillside on a typical neuroleptic and then had their medication changed to clozapine. |
1998-05-21 |
2023-08-12 |
Not clear |
| J S Brar, K N Chengappa, H Parepally, A R Sandman, S B Kreinbrook, S A Sheth, R Gangul. The effects of clozapine on negative symptoms in patients with schizophrenia with minimal positive symptoms. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 9. issue 4. 1998-05-20. PMID:9511946. |
the effects of clozapine on negative symptoms in patients with schizophrenia with minimal positive symptoms. |
1998-05-20 |
2023-08-12 |
Not clear |
| J S Brar, K N Chengappa, H Parepally, A R Sandman, S B Kreinbrook, S A Sheth, R Gangul. The effects of clozapine on negative symptoms in patients with schizophrenia with minimal positive symptoms. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 9. issue 4. 1998-05-20. PMID:9511946. |
the effectiveness of clozapine in the treatment of the negative symptoms of schizophrenia remains controversial, as improvements in negative symptoms are invariably accompanied by improvements in positive symptoms and neurological side effects. |
1998-05-20 |
2023-08-12 |
Not clear |
| J L Waddington, P J Scully, E O'Callagha. The new antipsychotics, and their potential for early intervention in schizophrenia. Schizophrenia research. vol 28. issue 2-3. 1998-05-14. PMID:9468355. |
this article first evaluates the significance of clozapine and risperidone; it then reviews some of the new antipsychotics and how they might be classified vis-a-vis potential advantages for patients, outlines putative mechanisms and new therapeutic targets, and considers whether such agents may act on any disease process inherent to schizophrenia. |
1998-05-14 |
2023-08-12 |
Not clear |
| J S Trayer, D C Fidle. Neuroleptic malignant syndrome related to use of clozapine. The Journal of the American Osteopathic Association. vol 98. issue 3. 1998-05-14. PMID:9558834. |
the patient had a history of schizophrenia and was being treated with clozapine. |
1998-05-14 |
2023-08-12 |
Not clear |
| L K Jacobsen, J L Rapopor. Research update: childhood-onset schizophrenia: implications of clinical and neurobiological research. Journal of child psychology and psychiatry, and allied disciplines. vol 39. issue 1. 1998-05-13. PMID:9534088. |
findings from these studies indicate that children can be diagnosed with schizophrenia using unmodified dsm-iii, -iiir, and -iv criteria, and that the atypical neuroleptic clozapine is an effective medication for this treatment refractory group. |
1998-05-13 |
2023-08-12 |
Not clear |
| J Liégeois, L Eyrolles, J Bruhwyler, J Delarg. Dopamine D4 receptors: a new opportunity for research on schizophrenia. Current medicinal chemistry. vol 5. issue 2. 1998-05-08. PMID:9481035. |
currently, although the first clinical report was very disappointing, the observation which support the idea that d4 might serve as a target for clozapine have significantly modified and extended the understanding of mechanism underlying atypical antipsychotic treatment of schizophrenia. |
1998-05-08 |
2023-08-12 |
Not clear |