| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mei-Kuei Wu, Chin-Kun Wang, Ya-Mei Bai, Chih-Yang Huang, Shin-Da Le. Outcomes of obese, clozapine-treated inpatients with schizophrenia placed on a six-month diet and physical activity program. Psychiatric services (Washington, D.C.). vol 58. issue 4. 2007-07-16. PMID:17412858. |
patients with schizophrenia treated with clozapine often gain weight. |
2007-07-16 |
2023-08-12 |
Not clear |
| Mei-Kuei Wu, Chin-Kun Wang, Ya-Mei Bai, Chih-Yang Huang, Shin-Da Le. Outcomes of obese, clozapine-treated inpatients with schizophrenia placed on a six-month diet and physical activity program. Psychiatric services (Washington, D.C.). vol 58. issue 4. 2007-07-16. PMID:17412858. |
this study evaluated the effects of dietary control and physical activity among obese inpatients with schizophrenia being treated with clozapine. |
2007-07-16 |
2023-08-12 |
Not clear |
| Xiang Yang Zhang, Yun Long Tan, Dong Feng Zhou, Colin N Haile, Lian Yuan Cao, Qi Xu, Yan Shen, Therese A Kosten, Thomas R Koste. Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population. Journal of clinical psychopharmacology. vol 27. issue 3. 2007-07-13. PMID:17502770. |
we investigated whether a leptin gene promoter variant affected weight gain after long-term treatment with clozapine in chronic schizophrenia. |
2007-07-13 |
2023-08-12 |
Not clear |
| Xiang Yang Zhang, Yun Long Tan, Dong Feng Zhou, Colin N Haile, Lian Yuan Cao, Qi Xu, Yan Shen, Therese A Kosten, Thomas R Koste. Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population. Journal of clinical psychopharmacology. vol 27. issue 3. 2007-07-13. PMID:17502770. |
leptin g2548a polymorphism was genotyped in 102 chinese han inpatients with chronic schizophrenia treated with clozapine. |
2007-07-13 |
2023-08-12 |
Not clear |
| Xiang Yang Zhang, Yun Long Tan, Dong Feng Zhou, Colin N Haile, Lian Yuan Cao, Qi Xu, Yan Shen, Therese A Kosten, Thomas R Koste. Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population. Journal of clinical psychopharmacology. vol 27. issue 3. 2007-07-13. PMID:17502770. |
thus, variation in the leptin gene may be a risk factor for weight gain in male patients with schizophrenia on long-term clozapine treatment. |
2007-07-13 |
2023-08-12 |
Not clear |
| John Crill. The history of clozapine and its emergence in the US market: a review and analysis. History of psychiatry. vol 18. issue 1. 2007-07-06. PMID:17580753. |
clozapine is known as the first 'atypical' medication and is effective in people who have treatment-resistant schizophrenia. |
2007-07-06 |
2023-08-12 |
Not clear |
| Oliver Freudenreich, David C Henderson, Jared P Walsh, Melissa A Culhane, Donald C Gof. Risperidone augmentation for schizophrenia partially responsive to clozapine: a double-blind, placebo-controlled trial. Schizophrenia research. vol 92. issue 1-3. 2007-07-03. PMID:17321111. |
risperidone augmentation for schizophrenia partially responsive to clozapine: a double-blind, placebo-controlled trial. |
2007-07-03 |
2023-08-12 |
Not clear |
| Oliver Freudenreich, David C Henderson, Jared P Walsh, Melissa A Culhane, Donald C Gof. Risperidone augmentation for schizophrenia partially responsive to clozapine: a double-blind, placebo-controlled trial. Schizophrenia research. vol 92. issue 1-3. 2007-07-03. PMID:17321111. |
risperidone augmentation of clozapine in refractory schizophrenia has theoretical but only inconsistent support from clinical trials. |
2007-07-03 |
2023-08-12 |
Not clear |
| Wiesław J Cubała, Hubert M Wichowicz, Jerzy Landowsk. Refractory schizophrenia treated with clozapine combined with zuclopenthixol. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 3. 2007-06-26. PMID:17258371. |
refractory schizophrenia treated with clozapine combined with zuclopenthixol. |
2007-06-26 |
2023-08-12 |
Not clear |
| Robert Kerwi. When should clozapine be initiated in schizophrenia?: Some arguments for and against earlier use of clozapine. CNS drugs. vol 21. issue 4. 2007-06-26. PMID:17381182. |
when should clozapine be initiated in schizophrenia? |
2007-06-26 |
2023-08-12 |
Not clear |
| Robert Kerwi. When should clozapine be initiated in schizophrenia?: Some arguments for and against earlier use of clozapine. CNS drugs. vol 21. issue 4. 2007-06-26. PMID:17381182. |
this article considers some of the arguments for unshackling clozapine from its current license for schizophrenia (its superiority overall in treatment-resistant schizophrenia, its potential for use in first-episode patients, and its anti-suicidal potential), and tries to synthesise these into some of the national guidelines available for the treatment of schizophrenia. |
2007-06-26 |
2023-08-12 |
Not clear |
| Yasin Genç, Ender Taner, Selcuk Candansaya. Comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: a single-blind randomized study. Advances in therapy. vol 24. issue 1. 2007-06-22. PMID:17526456. |
comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: a single-blind randomized study. |
2007-06-22 |
2023-08-12 |
Not clear |
| Yasin Genç, Ender Taner, Selcuk Candansaya. Comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: a single-blind randomized study. Advances in therapy. vol 24. issue 1. 2007-06-22. PMID:17526456. |
clozapine has long been the gold standard for treatment of patients with treatment-resistant schizophrenia; however, some patients are only partially responsive to clozapine treatment. |
2007-06-22 |
2023-08-12 |
Not clear |
| Deanna L Kelly, Robert R Conley, Stephanie Feldman, Yang Yu, Robert P McMahon, Charles M Richardso. Adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia. The Psychiatric quarterly. vol 77. issue 1. 2007-06-14. PMID:16397757. |
adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia. |
2007-06-14 |
2023-08-12 |
Not clear |
| Deanna L Kelly, Robert R Conley, Stephanie Feldman, Yang Yu, Robert P McMahon, Charles M Richardso. Adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia. The Psychiatric quarterly. vol 77. issue 1. 2007-06-14. PMID:16397757. |
this retrospective study examined adjunct divalproex (n = 15) or lithium (n = 9) in treatment-resistant schizophrenia patients added to clozapine and compared to clozapine monotherapy (n = 25). |
2007-06-14 |
2023-08-12 |
Not clear |
| Gaetana Migliardi, Concetta D'Arrigo, Vincenza Santoro, Antonio Bruno, Lara Cortese, Domenica Campolo, Massimo Cacciola, Edoardo Spin. Effect of topiramate on plasma concentrations of clozapine, olanzapine, risperidone, and quetiapine in patients with psychotic disorders. Clinical neuropharmacology. vol 30. issue 2. 2007-06-13. PMID:17414943. |
to investigate the effect of topiramate on the steady-state plasma concentrations of the second-generation antipsychotics--clozapine, olanzapine, risperidone, and quetiapine--in patients with schizophrenia or bipolar disorder. |
2007-06-13 |
2023-08-12 |
Not clear |
| Francisco J Diaz, Tulia E Rivera, Richard C Josiassen, Jose de Leo. Individualizing drug dosage by using a random intercept linear model. Statistics in medicine. vol 26. issue 9. 2007-05-31. PMID:16847902. |
computations are illustrated for clozapine, an antipsychotic drug used to treat patients with severe schizophrenia. |
2007-05-31 |
2023-08-12 |
Not clear |
| Neil D Woodward, Karu Jayathilake, Herbert Y Meltze. COMT val108/158met genotype, cognitive function, and cognitive improvement with clozapine in schizophrenia. Schizophrenia research. vol 90. issue 1-3. 2007-05-30. PMID:17123785. |
comt val108/158met genotype, cognitive function, and cognitive improvement with clozapine in schizophrenia. |
2007-05-30 |
2023-08-12 |
Not clear |
| Sarah M Turgeon, Virginia C Hulic. Differential effects of acute and subchronic clozapine and haloperidol on phencyclidine-induced decreases in voluntary sucrose consumption in rats. Pharmacology, biochemistry, and behavior. vol 86. issue 3. 2007-05-22. PMID:17320157. |
given that atypical antipsychotics have been shown to ameliorate negative symptoms of schizophrenia more effectively than typical neuroleptics, this effect should be reversed by clozapine but not haloperidol. |
2007-05-22 |
2023-08-12 |
rat |
| Edward D Levin, D Patrick Caldwell, Charles Perrau. Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response. Pharmacology, biochemistry, and behavior. vol 86. issue 3. 2007-05-22. PMID:17355891. |
this may be relevant to the action of clozapine in attenuating sensory gating deficits in schizophrenia and may point to new avenues of treatment for sensory modulation disorders in which there is excessive tactile response. |
2007-05-22 |
2023-08-12 |
rat |