| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ric M Procyshyn, Kishor M Wasan, Allen E Thornton, Alasdair M Barr, Eric Y H Chen, Edith Pomarol-Clotet, Emmanuel Stip, Richard Williams, G William Macewan, C Laird Birmingham, William G Hone. Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. Journal of psychiatry & neuroscience : JPN. vol 32. issue 5. 2007-10-29. PMID:17823649. |
the primary objective of this study was to determine whether an increase in serum lipids is associated with improvement in schizophrenia symptoms during steady state treatment with clozapine. |
2007-10-29 |
2023-08-12 |
Not clear |
| S Rathore, N D Masani, P O Callagha. Clozapine-induced effuso-constrictive pericarditis. Case report and review of the literature. Cardiology. vol 108. issue 3. 2007-10-25. PMID:17085936. |
clozapine is a widely used antipsychotic medication and is effective against both positive and negative symptoms of schizophrenia. |
2007-10-25 |
2023-08-12 |
Not clear |
| V Molina, J Sanz, F Sarramea, T Palom. Marked hypofrontality in clozapine-responsive patients. Pharmacopsychiatry. vol 40. issue 4. 2007-10-25. PMID:17694479. |
it seemed of interest to study the brain activity patterns after treatment with clozapine, since this drug might correct basal deficits directly related to schizophrenia or instead induce changes that would in some way compensate distant abnormalities. |
2007-10-25 |
2023-08-12 |
human |
| V Molina, J Sanz, F Sarramea, T Palom. Marked hypofrontality in clozapine-responsive patients. Pharmacopsychiatry. vol 40. issue 4. 2007-10-25. PMID:17694479. |
we compared metabolic patterns in 23 treatment-resistant (tr) patients after 6 months of treatment with clozapine, eighteen healthy subjects, and 17 nn schizophrenia patients. |
2007-10-25 |
2023-08-12 |
human |
| V Molina, J Sanz, F Sarramea, T Palom. Marked hypofrontality in clozapine-responsive patients. Pharmacopsychiatry. vol 40. issue 4. 2007-10-25. PMID:17694479. |
in conclusion, our results support a preferential role for prefrontal regions and their subcortical connections in the mechanism of action of clozapine, resulting in a clearly hypofrontal state as compared to both controls and schizophrenia patients without previous treatment. |
2007-10-25 |
2023-08-12 |
human |
| Oliver Freudenreich, Rajesh T Gandhi, Jared P Walsh, David C Henderson, Donald C Gof. Hepatitis C in schizophrenia: screening experience in a community-dwelling clozapine cohort. Psychosomatics. vol 48. issue 5. 2007-10-11. PMID:17878499. |
hepatitis c in schizophrenia: screening experience in a community-dwelling clozapine cohort. |
2007-10-11 |
2023-08-12 |
Not clear |
| Oliver Freudenreich, Rajesh T Gandhi, Jared P Walsh, David C Henderson, Donald C Gof. Hepatitis C in schizophrenia: screening experience in a community-dwelling clozapine cohort. Psychosomatics. vol 48. issue 5. 2007-10-11. PMID:17878499. |
to determine the prevalence of hepatitis c in a diagnostically well-defined sample, the authors screened all schizophrenia outpatients in a clozapine clinic (n=98) for hcv antibodies. |
2007-10-11 |
2023-08-12 |
Not clear |
| Patricia Zipris, Yuval Melamed, Abraham Weizman, Avi Bleic. Clozapine-induced eosinophilia and switch to quetiapine in a patient with chronic schizophrenia with suicidal tendencies. The Israel journal of psychiatry and related sciences. vol 44. issue 1. 2007-10-04. PMID:17665812. |
clozapine has proven effective in reducing morbidity and suicidality in chronic non-remitting patients with schizophrenia. |
2007-10-04 |
2023-08-12 |
Not clear |
| Yi-lang Tang, Peixian Mao, Feng-Min Li, Wenbiao Li, Qi Chen, Feng Jiang, Zhuo-ji Cai, Philip B Mitchel. Gender, age, smoking behaviour and plasma clozapine concentrations in 193 Chinese inpatients with schizophrenia. British journal of clinical pharmacology. vol 64. issue 1. 2007-09-27. PMID:17298477. |
gender, age, smoking behaviour and plasma clozapine concentrations in 193 chinese inpatients with schizophrenia. |
2007-09-27 |
2023-08-12 |
Not clear |
| Yi-lang Tang, Peixian Mao, Feng-Min Li, Wenbiao Li, Qi Chen, Feng Jiang, Zhuo-ji Cai, Philip B Mitchel. Gender, age, smoking behaviour and plasma clozapine concentrations in 193 Chinese inpatients with schizophrenia. British journal of clinical pharmacology. vol 64. issue 1. 2007-09-27. PMID:17298477. |
to study the relationship between age, gender, cigarette smoking and plasma concentrations of clozapine (clz) and its metabolite, norclozapine (nclz) in chinese patients with schizophrenia. |
2007-09-27 |
2023-08-12 |
Not clear |
| Divya Vohor. Atypical antipsychotic drugs: current issues of safety and efficacy in the management of schizophrenia. Current opinion in investigational drugs (London, England : 2000). vol 8. issue 7. 2007-09-04. PMID:17659473. |
this review focuses on the comparative safety and efficacy profile of nine atypical antipsychotic drugs (amisulpride, aripiprazole, clozapine, olanzapine, quetiapine, risperidone, sertindole, ziprasidone and zotepine), which may ultimately affect the therapeutic options available for patients with schizophrenia. |
2007-09-04 |
2023-08-12 |
Not clear |
| R Zoccali, M R Muscatello, A Bruno, R Cambria, U Micò, E Spina, M Medur. The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: a double-blind, placebo-controlled study. Schizophrenia research. vol 93. issue 1-3. 2007-08-30. PMID:17383857. |
the findings provide evidence that lamotrigine augmentation of clozapine treatment is well tolerated and may be proposed as an effective therapeutic strategy to improve outcome in treatment-resistant schizophrenia. |
2007-08-30 |
2023-08-12 |
Not clear |
| Ren-Rong Wu, Jing-Ping Zhao, Jin-Guo Zhai, Xiao-Feng Guo, Wen-Bin Gu. Sex difference in effects of typical and atypical antipsychotics on glucose-insulin homeostasis and lipid metabolism in first-episode schizophrenia. Journal of clinical psychopharmacology. vol 27. issue 4. 2007-08-28. PMID:17632222. |
the present study was to investigate the sex difference in effects of clozapine, olanzapine, risperidone, and sulpiride on glucose and lipid metabolism in first-episode schizophrenia. |
2007-08-28 |
2023-08-12 |
Not clear |
| Maria A Rettenbacher, Martina Hummer, Alex Hofer, Susanne Baumgartner, Christoph Ebenbichler, Monika Edlinger, Georg Kemmler, Monika Lechleitner, W Wolfgang Fleischhacke. Alterations of glucose metabolism during treatment with clozapine or amisulpride: results from a prospective 16-week study. Journal of psychopharmacology (Oxford, England). vol 21. issue 4. 2007-08-24. PMID:17050656. |
we conducted a prospective, open study comparing body weight, parameters of insulin resistance in schizophrenia patients treated with either clozapine (n = 10) or amisulpride ( n = 12). |
2007-08-24 |
2023-08-12 |
Not clear |
| Kanapathippillai Karunakaran, Tongeji E Tungaraza, Giles C Harborn. Is clozapine-aripiprazole combination a useful regime in the management of treatment-resistant schizophrenia? Journal of psychopharmacology (Oxford, England). vol 21. issue 4. 2007-08-24. PMID:17050662. |
around 40-70% patients with treatment-resistant schizophrenia fail to respond to clozapine. |
2007-08-24 |
2023-08-12 |
Not clear |
| Kanapathippillai Karunakaran, Tongeji E Tungaraza, Giles C Harborn. Is clozapine-aripiprazole combination a useful regime in the management of treatment-resistant schizophrenia? Journal of psychopharmacology (Oxford, England). vol 21. issue 4. 2007-08-24. PMID:17050662. |
though combining antipsychotics is commonly practised with non-responders, there is little evidence for its use.we carried out a retrospective review of case notes of patients with treatment-resistant schizophrenia on clozapine-aripiprazole combination at our clozapine clinic. |
2007-08-24 |
2023-08-12 |
Not clear |
| T Abekawa, K Ito, T Koyam. Role of the simultaneous enhancement of NMDA and dopamine D1 receptor-mediated neurotransmission in the effects of clozapine on phencyclidine-induced acute increases in glutamate levels in the rat medial prefrontal cortex. Naunyn-Schmiedeberg's archives of pharmacology. vol 374. issue 3. 2007-07-30. PMID:17103144. |
clozapine (clz) can improve both the positive and negative symptoms of treatment-resistant schizophrenia (trs), which does not respond to typical antipsychotics. |
2007-07-30 |
2023-08-12 |
rat |
| Carol Paton, Craig Whittington, Thomas R Barne. Augmentation with a second antipsychotic in patients with schizophrenia who partially respond to clozapine: a meta-analysis. Journal of clinical psychopharmacology. vol 27. issue 2. 2007-07-30. PMID:17414246. |
augmentation with a second antipsychotic in patients with schizophrenia who partially respond to clozapine: a meta-analysis. |
2007-07-30 |
2023-08-12 |
Not clear |
| Carol Paton, Craig Whittington, Thomas R Barne. Augmentation with a second antipsychotic in patients with schizophrenia who partially respond to clozapine: a meta-analysis. Journal of clinical psychopharmacology. vol 27. issue 2. 2007-07-30. PMID:17414246. |
to conduct a meta-analysis of randomized placebo-controlled trials (rcts) of clozapine augmentation with another antipsychotic drug in patient with schizophrenia who partially respond to clozapine and compare the results with the findings of relevant open studies. |
2007-07-30 |
2023-08-12 |
Not clear |
| Luiz Dratcu, Alistair Grandison, Gavin McKay, Adekunle Bamidele, Vinodini Vasudeva. Clozapine-resistant psychosis, smoking, and caffeine: managing the neglected effects of substances that our patients consume every day. American journal of therapeutics. vol 14. issue 3. 2007-07-19. PMID:17515710. |
we describe 2 male patients with severe treatment-resistant psychosis, one with schizophrenia and the other with bipolar affective disorder-both of whom smoked heavily, and the latter also consumed enormous amounts of caffeine-whose symptoms were refractory to clozapine. |
2007-07-19 |
2023-08-12 |
Not clear |