| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Dervaux, X Laqueill. [Tobacco and schizophrenia: therapeutic aspects]. L'Encephale. vol 33. issue 4 Pt 1. 2008-02-19. PMID:18033154. |
atypical antipsychotics may reduce smoking consumption in schizophrenia patients, in particular clozapine. |
2008-02-19 |
2023-08-12 |
Not clear |
| A Elif Anil Yağcioğl. [The mechanisms of action of antipsychotic drugs: is atypicality superior in schizophrenia treatment?]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 18. issue 4. 2008-02-19. PMID:18066727. |
in the final section, some specific mechanisms of action, which might be related to clozapine's superiority in schizophrenia treatment, will be examined. |
2008-02-19 |
2023-08-12 |
Not clear |
| Rudi Hwang, Takahiro Shinkai, Vincenzo De Luca, Xingqun Ni, Steven G Potkin, Jeffrey A Lieberman, Herbert Y Meltzer, James L Kenned. Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response. Journal of psychopharmacology (Oxford, England). vol 21. issue 7. 2008-02-15. PMID:17092969. |
therefore pharmacologic agents with potent d1 effects such as clozapine may influence the symptoms of schizophrenia (scz). |
2008-02-15 |
2023-08-12 |
Not clear |
| Zhu Li, Douglas W Bonhaus, Mei Huang, Adam J Prus, Jin Dai, Herbert Y Meltze. AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus. European journal of pharmacology. vol 572. issue 2-3. 2008-01-14. PMID:17628522. |
we have previously suggested that stimulation of the muscarinic m1 receptor has a beneficial effect on cognition, based upon evidence that the muscarinic m1 receptor agonist of n-desmethylclozapine, the major metabolite of clozapine, may contribute to the ability of clozapine to improve some domains of cognition in schizophrenia. |
2008-01-14 |
2023-08-12 |
rat |
| Ya Mei Bai, Jen-Yeu Chen, Wei-Shiung Yang, Yu-Chiao Chi, Ying-Jay Liou, Chao-Cheng Lin, Ying-Chieh Wang, Chih-Yuan Lin, Tung-Pine Su, Pesus Cho. Adiponectin as a potential biomarker for the metabolic syndrome in Chinese patients taking clozapine for schizophrenia. The Journal of clinical psychiatry. vol 68. issue 12. 2008-01-10. PMID:18162013. |
adiponectin as a potential biomarker for the metabolic syndrome in chinese patients taking clozapine for schizophrenia. |
2008-01-10 |
2023-08-12 |
Not clear |
| Ya Mei Bai, Jen-Yeu Chen, Wei-Shiung Yang, Yu-Chiao Chi, Ying-Jay Liou, Chao-Cheng Lin, Ying-Chieh Wang, Chih-Yuan Lin, Tung-Pine Su, Pesus Cho. Adiponectin as a potential biomarker for the metabolic syndrome in Chinese patients taking clozapine for schizophrenia. The Journal of clinical psychiatry. vol 68. issue 12. 2008-01-10. PMID:18162013. |
the aim of this study is to determine the possible relationship between adiponectin and the metabolic syndrome among chinese patients taking clozapine for schizophrenia. |
2008-01-10 |
2023-08-12 |
Not clear |
| B Grayson, N F Idris, J C Neil. Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat. Behavioural brain research. vol 184. issue 1. 2008-01-09. PMID:17675172. |
clozapine and risperidone but not haloperidol showed efficacy to reverse the deficit induced by sub-chronic pcp suggesting that this test may have some validity for assessing efficacy for improvement of cognitive deficit symptoms of schizophrenia. |
2008-01-09 |
2023-08-12 |
rat |
| Alain Dervaux, Joelle Cazal. Clozapine and amisulpride in refractory schizophrenia and alcohol dependence. Journal of clinical psychopharmacology. vol 27. issue 5. 2008-01-02. PMID:17873688. |
clozapine and amisulpride in refractory schizophrenia and alcohol dependence. |
2008-01-02 |
2023-08-12 |
Not clear |
| Yao Feng-Ju, Sun Fu-Gen, Zhang Zhi-Hu. [Short-term curative effect of electroacupuncture as an adjunctive treatment on schizophrenia]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 26. issue 3. 2007-12-27. PMID:16613275. |
to compare the short-term curative effect of clozapine (cz) and its combination with electroacupuncture (ea) in treating schizophrenia. |
2007-12-27 |
2023-08-12 |
Not clear |
| Steven C Stoner, Megan M Dahmen, Arnaldo Berges, Whitney M Petr. Augmentation of aripiprazole with low-dose clozapine. Pharmacotherapy. vol 27. issue 11. 2007-12-20. PMID:17963467. |
the standard of care for treating schizophrenia is to first use monotherapy of adequate dosage and duration, including a trial of clozapine before adding a second agent. |
2007-12-20 |
2023-08-12 |
Not clear |
| J A W Benckhuijsen, I P M Kee. [Delirium on re-starting clozapine after a short break in treatment]. Tijdschrift voor psychiatrie. vol 49. issue 9. 2007-12-18. PMID:17853376. |
a 44-year-old man with schizophrenia developed delirium on two occasions immediately after restarting clozapine at the dosage he had previously tolerated well; the clozapine-free periods had lasted 2 and 10 days respectively. |
2007-12-18 |
2023-08-12 |
Not clear |
| Xiang Yang Zhang, Yun Long Tan, Dong Feng Zhou, Lian Yuan Cao, Gui Ying Wu, Qi Xu, Yan Shen, Colin N Haile, Therese A Kosten, Thomas R Koste. Serum BDNF levels and weight gain in schizophrenic patients on long-term treatment with antipsychotics. Journal of psychiatric research. vol 41. issue 12. 2007-12-13. PMID:17095017. |
serum bdnf was measured in 124 schizophrenia patients chronically treated with clozapine (n=57), risperidone (n=23) or typical antipsychotics (n=44) and 50 healthy control subjects. |
2007-12-13 |
2023-08-12 |
human |
| Deanna L Kelly, Julie Kreyenbuhl, Lisa Dixon, Raymond C Love, Deborah Medoff, Robert R Conle. Clozapine underutilization and discontinuation in African Americans due to leucopenia. Schizophrenia bulletin. vol 33. issue 5. 2007-12-06. PMID:17170061. |
we examined the rates of leucopenia and agranulocytosis as reasons for discontinuation of clozapine in a sample of 1875 patients with schizophrenia treated in the state of maryland. |
2007-12-06 |
2023-08-12 |
Not clear |
| Helio Elki. Treatment-resistant schizophrenia. The Psychiatric clinics of North America. vol 30. issue 3. 2007-11-21. PMID:17720034. |
it then discusses the definition and treatment of treatment-resistant schizophrenia, with particular attention to clinical, biological and neuroimaging correlates, as well as the best treatment options, including the use of clozapine in patients who meet the definition of treatment-resistant schizophrenia. |
2007-11-21 |
2023-08-12 |
Not clear |
| Xavier López-Gil, Zoila Babot, Mercè Amargós-Bosch, Cristina Suñol, Francesc Artigas, Albert Adel. Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 10. 2007-11-20. PMID:17356574. |
the ability of clozapine to block excessive cortical 5-ht efflux elicited by mk-801 might be related to the superior efficacy of this drug in treating negative/cognitive symptoms of schizophrenia. |
2007-11-20 |
2023-08-12 |
rat |
| Lorenzo Pelizza, Pasquale De Luca, Maurizio La Pesa, Daniela Borell. Clozapine-induced intestinal occlusion: a serious side effect. Acta bio-medica : Atenei Parmensis. vol 78. issue 2. 2007-11-19. PMID:17933283. |
aim of this article is to describe the first italian case reported in literature of a clozapine-induced intestinal occlusion with previous severe constipation in a 45-year-old male patient who had been treated with daily clozapine for 5 months because of treatment-resistant residual schizophrenia. |
2007-11-19 |
2023-08-12 |
Not clear |
| Alexandra L Sporn, Anoop Vermani, Deanna K Greenstein, Aaron J Bobb, Edgar P Spencer, Liv S Clasen, Julia W Tossell, Catherine C Stayer, Peter A Gochman, Marge C Lenane, Judith L Rapoport, Nitin Gogta. Clozapine treatment of childhood-onset schizophrenia: evaluation of effectiveness, adverse effects, and long-term outcome. Journal of the American Academy of Child and Adolescent Psychiatry. vol 46. issue 10. 2007-11-08. PMID:17885577. |
clozapine treatment of childhood-onset schizophrenia: evaluation of effectiveness, adverse effects, and long-term outcome. |
2007-11-08 |
2023-08-12 |
Not clear |
| Alexandra L Sporn, Anoop Vermani, Deanna K Greenstein, Aaron J Bobb, Edgar P Spencer, Liv S Clasen, Julia W Tossell, Catherine C Stayer, Peter A Gochman, Marge C Lenane, Judith L Rapoport, Nitin Gogta. Clozapine treatment of childhood-onset schizophrenia: evaluation of effectiveness, adverse effects, and long-term outcome. Journal of the American Academy of Child and Adolescent Psychiatry. vol 46. issue 10. 2007-11-08. PMID:17885577. |
clozapine is a unique atypical antipsychotic with superior efficacy in treatment-resistant schizophrenia. |
2007-11-08 |
2023-08-12 |
Not clear |
| Umit B Semiz, Mesut Cetin, Cengiz Basoglu, Servet Ebrinc, Ozcan Uzun, Hasan Herken, Hakan Balibey, Ayhan Algul, Alpay Ate. Clinical predictors of therapeutic response to clozapine in a sample of Turkish patients with treatment-resistant schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 6. 2007-10-31. PMID:17618026. |
clinical predictors of therapeutic response to clozapine in a sample of turkish patients with treatment-resistant schizophrenia. |
2007-10-31 |
2023-08-12 |
Not clear |
| Umit B Semiz, Mesut Cetin, Cengiz Basoglu, Servet Ebrinc, Ozcan Uzun, Hasan Herken, Hakan Balibey, Ayhan Algul, Alpay Ate. Clinical predictors of therapeutic response to clozapine in a sample of Turkish patients with treatment-resistant schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 6. 2007-10-31. PMID:17618026. |
several lines of evidence suggest that clozapine is more effective than both first- and second-generation antipsychotic drugs in treatment-resistant schizophrenia (trs). |
2007-10-31 |
2023-08-12 |
Not clear |