| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zahra Isnaini Mohamed, Shiau Foon Tee, Tze Jen Chow, Siew Yim Loh, Hoi Sen Yong, Abdul Kadir Abu Bakar, Pek Yee Tan. Functional characterization of two variants in the 3'-untranslated region (UTR) of transcription factor 4 gene and their association with schizophrenia in sib-pairs from multiplex families. Asian journal of psychiatry. vol 40. 2019-07-29. PMID:30771755. |
since mirnas regulate targetgenes by binding to 3'utrs of target mrnas, the functional variants located in 3'utr of tcf4 are highly suggested to affect the gene expressions in schizophrenia. |
2019-07-29 |
2023-08-13 |
Not clear |
| Zahra Isnaini Mohamed, Shiau Foon Tee, Tze Jen Chow, Siew Yim Loh, Hoi Sen Yong, Abdul Kadir Abu Bakar, Pek Yee Tan. Functional characterization of two variants in the 3'-untranslated region (UTR) of transcription factor 4 gene and their association with schizophrenia in sib-pairs from multiplex families. Asian journal of psychiatry. vol 40. 2019-07-29. PMID:30771755. |
in this study, we sequenced the 3'utr of tcf4 in 13 multiplex schizophrenia families and 14 control families. |
2019-07-29 |
2023-08-13 |
Not clear |
| Zahra Isnaini Mohamed, Shiau Foon Tee, Tze Jen Chow, Siew Yim Loh, Hoi Sen Yong, Abdul Kadir Abu Bakar, Pek Yee Tan. Functional characterization of two variants in the 3'-untranslated region (UTR) of transcription factor 4 gene and their association with schizophrenia in sib-pairs from multiplex families. Asian journal of psychiatry. vol 40. 2019-07-29. PMID:30771755. |
our results suggested that rs1273263 is a potential regulator of tcf4 expression, and might be associated with schizophrenia. |
2019-07-29 |
2023-08-13 |
Not clear |
| Javad Tavakkoly-Bazzaz, Asaad Azarnezhad, Negar Mousavi, Pouya Salehipour, Esmaeil Shahsavand Ananloo, Fatemeh Alizade. TCF4 and GRM8 gene polymorphisms and risk of schizophrenia in an Iranian population: a case-control study. Molecular biology reports. vol 45. issue 6. 2019-04-25. PMID:30288643. |
tcf4 and grm8 gene polymorphisms and risk of schizophrenia in an iranian population: a case-control study. |
2019-04-25 |
2023-08-13 |
Not clear |
| Javad Tavakkoly-Bazzaz, Asaad Azarnezhad, Negar Mousavi, Pouya Salehipour, Esmaeil Shahsavand Ananloo, Fatemeh Alizade. TCF4 and GRM8 gene polymorphisms and risk of schizophrenia in an Iranian population: a case-control study. Molecular biology reports. vol 45. issue 6. 2019-04-25. PMID:30288643. |
tcf4 and grm8, two significant genes involved in the normal nervous development and glutamate pathway, are thought to be involved in the pathogenesis of schizophrenia (scz). |
2019-04-25 |
2023-08-13 |
Not clear |
| Ruth Whelan, David St Clair, Colette J Mustard, Philomena Hallford, Jun We. Study of Novel Autoantibodies in Schizophrenia. Schizophrenia bulletin. vol 44. issue 6. 2019-03-19. PMID:29373732. |
of 18 antigens tested, 6 (derived from dpyd, mad1l1, znf804a, drd2, trank1, and mmp16, respectively) showed increased igg levels and 3 (derived from tsnare1, tcf4, and vrk2, respectively) showed decreased igg levels in patients with schizophrenia compared with control subjects. |
2019-03-19 |
2023-08-13 |
human |
| Hanzhang Xia, Fay M Jahr, Nak-Kyeong Kim, Linying Xie, Andrey A Shabalin, Julien Bryois, Douglas H Sweet, Mohamad M Kronfol, Preetha Palasuberniam, MaryPeace McRae, Brien P Riley, Patrick F Sullivan, Edwin J van den Oord, Joseph L McCla. Building a schizophrenia genetic network: transcription factor 4 regulates genes involved in neuronal development and schizophrenia risk. Human molecular genetics. vol 27. issue 18. 2019-03-12. PMID:29905862. |
the transcription factor 4 (tcf4) locus is a robust association finding with schizophrenia (scz), but little is known about the genes regulated by the encoded transcription factor. |
2019-03-12 |
2023-08-13 |
Not clear |
| Marc P Forrest, Matthew J Hill, David H Kavanagh, Katherine E Tansey, Adrian J Waite, Derek J Blak. The Psychiatric Risk Gene Transcription Factor 4 (TCF4) Regulates Neurodevelopmental Pathways Associated With Schizophrenia, Autism, and Intellectual Disability. Schizophrenia bulletin. vol 44. issue 5. 2019-02-08. PMID:29228394. |
common genetic variants in and around the gene encoding transcription factor 4 (tcf4) are associated with an increased risk of schizophrenia. |
2019-02-08 |
2023-08-13 |
Not clear |
| Fatemeh Alizadeh, Javad Tavakkoly-Bazzaz, Ali Bozorgmehr, Asa'ad Azarnezhad, Mina Tabrizi, Esmaeil Shahsavand Ananlo. Association of transcription factor 4 (TCF4) gene mRNA level with schizophrenia, its psychopathology, intelligence and cognitive impairments. Journal of neurogenetics. vol 31. issue 4. 2018-07-23. PMID:29105523. |
in this study, using real-time pcr, we compared tcf4 mrna level between the case (70 unmedicated schizophrenia patients) and healthy control (n = 72) groups. |
2018-07-23 |
2023-08-13 |
human |
| A V Bocharova, V A Stepanov, A V Marusin, V N Kharkov, K V Vagaitseva, O Yu Fedorenko, N A Bokhan, A V Semke, S A Ivanov. [Association study of genetic markers of schizophrenia and its cognitive endophenotypes]. Genetika. vol 53. issue 1. 2018-02-16. PMID:29372809. |
a replicative analysis of associations of 15 snps located in the regions of 11 genes (tcf4, vrk2, notch4, znf804a, agbl1, reln, zfp64p1, kcnb2, csmd1, cpvl, nrip1) and three intergenic regions (slco6a1/lincoo491, loc105376248/loc105376249, spa17/nrgn) with schizophrenia was conducted in the russian population of the siberian region. |
2018-02-16 |
2023-08-13 |
Not clear |
| Mari Sepp, Hanna Vihma, Kaja Nurm, Mari Urb, Stephanie Cerceo Page, Kaisa Roots, Anu Hark, Brady J Maher, Priit Pruunsild, Tõnis Timmus. The Intellectual Disability and Schizophrenia Associated Transcription Factor TCF4 Is Regulated by Neuronal Activity and Protein Kinase A. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 43. 2017-11-06. PMID:28951451. |
the intellectual disability and schizophrenia associated transcription factor tcf4 is regulated by neuronal activity and protein kinase a. |
2017-11-06 |
2023-08-13 |
rat |
| Mari Sepp, Hanna Vihma, Kaja Nurm, Mari Urb, Stephanie Cerceo Page, Kaisa Roots, Anu Hark, Brady J Maher, Priit Pruunsild, Tõnis Timmus. The Intellectual Disability and Schizophrenia Associated Transcription Factor TCF4 Is Regulated by Neuronal Activity and Protein Kinase A. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 43. 2017-11-06. PMID:28951451. |
transcription factor 4 (tcf4 also known as itf2 or e2-2) is a basic helix-loop-helix (bhlh) protein associated with pitt-hopkins syndrome, intellectual disability, and schizophrenia (scz). |
2017-11-06 |
2023-08-13 |
rat |
| Jingjie Li, Zhengshuai Chen, Fengjiao Wang, Yongri Ouyang, Ning Zhang, Min Yang, Mengdan Yan, Xikai Zhu, Xue He, Dongya Yuan, Tianbo Ji. Polymorphisms of the TCF4 gene are associated with the risk of schizophrenia in the Han Chinese. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 171. issue 8. 2017-09-21. PMID:27103199. |
polymorphisms of the tcf4 gene are associated with the risk of schizophrenia in the han chinese. |
2017-09-21 |
2023-08-13 |
Not clear |
| Tze Jen Chow, Shiau Foon Tee, Hoi Sen Yong, Pek Yee Tan. Genetic Association of TCF4 and AKT1 Gene Variants with the Age at Onset of Schizophrenia. Neuropsychobiology. vol 73. issue 4. 2017-02-07. PMID:27305091. |
genetic association of tcf4 and akt1 gene variants with the age at onset of schizophrenia. |
2017-02-07 |
2023-08-13 |
Not clear |
| Tze Jen Chow, Shiau Foon Tee, Hoi Sen Yong, Pek Yee Tan. Genetic Association of TCF4 and AKT1 Gene Variants with the Age at Onset of Schizophrenia. Neuropsychobiology. vol 73. issue 4. 2017-02-07. PMID:27305091. |
tcf4 and akt1 are schizophrenia risk genes involved in cognitive functions. |
2017-02-07 |
2023-08-13 |
Not clear |
| Tze Jen Chow, Shiau Foon Tee, Hoi Sen Yong, Pek Yee Tan. Genetic Association of TCF4 and AKT1 Gene Variants with the Age at Onset of Schizophrenia. Neuropsychobiology. vol 73. issue 4. 2017-02-07. PMID:27305091. |
the current study examined the interactive effects of tcf4 and akt1 variants with gender, family history of psychiatric disorders and ethnicity on the aao of schizophrenia. |
2017-02-07 |
2023-08-13 |
Not clear |
| Matthew D Rannals, Gregory R Hamersky, Stephanie Cerceo Page, Morganne N Campbell, Aaron Briley, Ryan A Gallo, BaDoi N Phan, Thomas M Hyde, Joel E Kleinman, Joo Heon Shin, Andrew E Jaffe, Daniel R Weinberger, Brady J Mahe. Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1. Neuron. vol 90. issue 1. 2016-08-15. PMID:26971948. |
transcription factor 4 (tcf4) is a clinically pleiotropic gene associated with schizophrenia and pitt-hopkins syndrome (pths). |
2016-08-15 |
2023-08-13 |
mouse |
| Li Hui, Wen-Wang Rao, Qiong Yu, Changgui Kou, Jing Qin Wu, Jin Cai He, Min Jie Ye, Jia Hong Liu, Xiao Jun Xu, Ke Zheng, Li Na Ruan, Hong Yang Liu, Wei Ming Hu, Tian Nan Shao, Michael B AngRabanes, Jair C Soares, Xiang Yang Zhan. TCF4 gene polymorphism is associated with cognition in patients with schizophrenia and healthy controls. Journal of psychiatric research. vol 69. 2016-06-07. PMID:26343600. |
tcf4 gene polymorphism is associated with cognition in patients with schizophrenia and healthy controls. |
2016-06-07 |
2023-08-13 |
Not clear |
| Li Hui, Wen-Wang Rao, Qiong Yu, Changgui Kou, Jing Qin Wu, Jin Cai He, Min Jie Ye, Jia Hong Liu, Xiao Jun Xu, Ke Zheng, Li Na Ruan, Hong Yang Liu, Wei Ming Hu, Tian Nan Shao, Michael B AngRabanes, Jair C Soares, Xiang Yang Zhan. TCF4 gene polymorphism is associated with cognition in patients with schizophrenia and healthy controls. Journal of psychiatric research. vol 69. 2016-06-07. PMID:26343600. |
single nucleotide polymorphisms in the transcription factor 4 (tcf4) gene have been reported to be involved in the susceptibility to schizophrenia and be significantly related to cognitive deficits of schizophrenia and controls. |
2016-06-07 |
2023-08-13 |
Not clear |
| Li Hui, Wen-Wang Rao, Qiong Yu, Changgui Kou, Jing Qin Wu, Jin Cai He, Min Jie Ye, Jia Hong Liu, Xiao Jun Xu, Ke Zheng, Li Na Ruan, Hong Yang Liu, Wei Ming Hu, Tian Nan Shao, Michael B AngRabanes, Jair C Soares, Xiang Yang Zhan. TCF4 gene polymorphism is associated with cognition in patients with schizophrenia and healthy controls. Journal of psychiatric research. vol 69. 2016-06-07. PMID:26343600. |
this study examines whether the tcf4 rs2958182 polymorphism influences cognitive functions in chronic schizophrenia and controls. |
2016-06-07 |
2023-08-13 |
Not clear |