Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Emma C Johnson, Douglas W Bjelland, Daniel P Howrigan, Abdel Abdellaoui, Gerome Breen, Anders Borglum, Sven Cichon, Franziska Degenhardt, Andreas J Forstner, Josef Frank, Giulio Genovese, Stefanie Heilmann-Heimbach, Stefan Herms, Per Hoffman, Wolfgang Maier, Manuel Mattheisen, Derek Morris, Bryan Mowry, Betram Müller-Mhysok, Benjamin Neale, Igor Nenadic, Markus M Nöthen, Colm O'Dushlaine, Marcella Rietschel, Douglas M Ruderfer, Dan Rujescu, Thomas G Schulze, Matthew A Simonson, Eli Stahl, Jana Strohmaier, Stephanie H Witt, Patrick F Sullivan, Matthew C Kelle. No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study. PLoS genetics. vol 12. issue 10. 2017-04-28. PMID:27792727. |
(2012) estimated that the odds of developing schizophrenia increased by approximately 17% for every additional percent of the genome that is autozygous (β = 16.1, ci(β) = [6.93, 25.7], z = 3.44, p = 0.0006). |
2017-04-28 |
2023-08-13 |
Not clear |
Emma C Johnson, Douglas W Bjelland, Daniel P Howrigan, Abdel Abdellaoui, Gerome Breen, Anders Borglum, Sven Cichon, Franziska Degenhardt, Andreas J Forstner, Josef Frank, Giulio Genovese, Stefanie Heilmann-Heimbach, Stefan Herms, Per Hoffman, Wolfgang Maier, Manuel Mattheisen, Derek Morris, Bryan Mowry, Betram Müller-Mhysok, Benjamin Neale, Igor Nenadic, Markus M Nöthen, Colm O'Dushlaine, Marcella Rietschel, Douglas M Ruderfer, Dan Rujescu, Thomas G Schulze, Matthew A Simonson, Eli Stahl, Jana Strohmaier, Stephanie H Witt, Patrick F Sullivan, Matthew C Kelle. No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study. PLoS genetics. vol 12. issue 10. 2017-04-28. PMID:27792727. |
(2012), we were unable to replicate the significant association between roh burden and schizophrenia in the independent pgc phase ii data, although the effect was in the predicted direction, and the combined (original + replication) dataset yielded an attenuated but significant relationship between froh and schizophrenia (β = 4.86,ci(β) = [0.90,8.83],z = 2.40,p = 0.02). |
2017-04-28 |
2023-08-13 |
Not clear |
Peng Yan, Xiaomeng Qiao, Hua Wu, Fangyuan Yin, Jing Zhang, Yuanyuan Ji, Shuguang Wei, Jianghua La. An Association Study Between Genetic Polymorphisms in Functional Regions of Five Genes and the Risk of Schizophrenia. Journal of molecular neuroscience : MN. vol 59. issue 3. 2017-03-16. PMID:27055860. |
the patients were significantly less likely to be cc homozygous (p = 0.005, odds ratio [or] = 0.635, 95 % confidence interval [95 % ci] = 0.462-0.873), and the schizophrenia subjects exhibited lower frequency of the c allele (p = 0.024, or = 0.811, 95 % ci = 0.676-0.972). |
2017-03-16 |
2023-08-13 |
human |
Yurong Wang, Li Liu, Lihong Xin, Dazhi Fan, Ning Ding, Yanting Hu, Guoqi Cai, Li Wang, Qing Xia, Xiaona Li, Xiao Yang, Yanfeng Zou, Faming Pa. The -141C Ins/Del and Taq1A polymorphism in the dopamine D2 receptor gene may confer susceptibility to schizophrenia in Asian populations. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 30. 2017-02-27. PMID:27283386. |
evidence regarding the association between -141c ins/del polymorphism and schizophrenia was found in the allele frequency comparison (ins versus del: or 1.29, 95% ci 1.06-1.57; p=0.01, praw=0.1, pfalse discovery rate=0.023). |
2017-02-27 |
2023-08-13 |
Not clear |
Bang-Shun He, Ling-Yun Zhang, Yu-Qin Pan, Kang Lin, Li-Li Zhang, Hui-Ling Sun, Tian-Yi Gao, Tai-Qin Su, Shu-Kui Wang, Cheng-Bin Zh. Association of the DISC1 and NRG1 genetic polymorphisms with schizophrenia in a Chinese population. Gene. vol 590. issue 2. 2017-01-30. PMID:27236031. |
the results revealed that the disc1 rs821616 heterozygous (at vs. aa: adjusted or, 1.98, 95%ci: 1.30-3.02) and co-dominant (at/tt vs. aa: adjusted or=1.94; 95%ci: 1.29-2.92) patterns were associated with increased risk for developing schizophrenia in all participants and subgroups (stratified by sex and age at onset), respectively. |
2017-01-30 |
2023-08-13 |
human |
A Sariaslan, S Fazel, B M D'Onofrio, N Långström, H Larsson, S E Bergen, R Kuja-Halkola, P Lichtenstei. Schizophrenia and subsequent neighborhood deprivation: revisiting the social drift hypothesis using population, twin and molecular genetic data. Translational psychiatry. vol 6. 2017-01-11. PMID:27138795. |
although the correlation between schizophrenia and neighborhood deprivation was moderate in magnitude (r=0.22; 95% ci: 0.20-0.24), it was entirely explained by genetic influences. |
2017-01-11 |
2023-08-13 |
Not clear |
Mascha M J Linszen, Rachel M Brouwer, Sophie M Heringa, Iris E Somme. Increased risk of psychosis in patients with hearing impairment: Review and meta-analyses. Neuroscience and biobehavioral reviews. vol 62. 2016-12-13. PMID:26743858. |
early exposure to hearing impairment elevated the risk of later development of schizophrenia (or 3.15(95%ci 1.25-7.95; n=50,490)). |
2016-12-13 |
2023-08-13 |
Not clear |
Faith Dickerson, Andrea Origoni, Jennifer Schroeder, Lucy A B Schweinfurth, Cassie Stallings, Christina L G Savage, Emily Katsafanas, Maria Banis, Sunil Khushalani, Robert Yolke. Mortality in schizophrenia and bipolar disorder: Clinical and serological predictors. Schizophrenia research. vol 170. issue 1. 2016-11-02. PMID:26607103. |
in the schizophrenia group, mortality was predicted by the following variables in a multivariate model: cigarette smoking (rr=6.93, 95% ci 1.59, 30.1, p=0.0099); autoimmune disorder (rr=8.08, 95% ci 2.50, 26.1, p=0.00047); gastrointestinal disorder (gi) (rr=3.53, 95% ci 1.43, 8.69 p=0.0061); and reduced maternal education (rr=0.84, 95% ci 0.72, 0.97), p=0.018. |
2016-11-02 |
2023-08-13 |
Not clear |
C Zhang, W Lu, Z Wang, J Ni, J Zhang, W Tang, Y Fan. A comprehensive analysis of NDST3 for schizophrenia and bipolar disorder in Han Chinese. Translational psychiatry. vol 6. 2016-10-17. PMID:26731438. |
the frequency of the rs11098403 g allele was significantly lower among schizophrenia patients than among the controls (odds ratio (or)=0.68, 95% confidence interval (ci): 0.55-0.84, corrected p=0.002). |
2016-10-17 |
2023-08-13 |
human |
C Zhang, W Lu, Z Wang, J Ni, J Zhang, W Tang, Y Fan. A comprehensive analysis of NDST3 for schizophrenia and bipolar disorder in Han Chinese. Translational psychiatry. vol 6. 2016-10-17. PMID:26731438. |
after pooling all data from 1861 patients with schizophrenia and 2081 controls, we observed a significant association of the rs11098403 g allele with schizophrenia (z=5.56, p<0.001), with an or=0.70 (95% ci: 0.61-0.79). |
2016-10-17 |
2023-08-13 |
human |
Mevhibe İrem Yıldız, Çağrı Temuçin, Aygün Ertuğru. [The Relationship of the Change in Symptoms and Cognitive Functions With the Change in Cortical Inhibition Parameters Measured by Transcranial Magnetic Stimulation: An Eight-Week Follow-Up Study]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 26. issue 3. 2016-09-15. PMID:26364170. |
transcranial magnetic stimulation (tms) studies show cortical inhibition (ci) abnormalities in patients with schizophrenia. |
2016-09-15 |
2023-08-13 |
Not clear |
Lei Cai, Tianlu Chen, Jinglei Yang, Kejun Zhou, Xiaomei Yan, Wenzhong Chen, Liya Sun, Linlin Li, Shengying Qin, Peng Wang, Ping Yang, Donghong Cui, Margit Burmeister, Lin He, Wei Jia, Chunling Wa. Serum trace element differences between Schizophrenia patients and controls in the Han Chinese population. Scientific reports. vol 5. 2016-08-22. PMID:26456296. |
the meta-analysis including 522 cases and 360 controls supported that zinc was significantly associated with schizophrenia (standardized mean difference [smd], -0.81; 95% confidence intervals [ci], -1.46 to -0.16, p = 0.01) in the random-effect model. |
2016-08-22 |
2023-08-13 |
human |
Brendon Stubbs, Trevor Thompson, Sarah Acaster, Davy Vancampfort, Fiona Gaughran, Christoph U Correl. Decreased pain sensitivity among people with schizophrenia: a meta-analysis of experimental pain induction studies. Pain. vol 156. issue 11. 2016-07-20. PMID:26207650. |
likewise, patients with schizophrenia had increased pain tolerance (es = 0.566; 95% ci, 0.235-0.897; p = 0.0001; studies = 6), sensory threshold (es = 1.16; 95% ci, 0.505-1.727; p < 0.0001; studies = 5), and pain threshold (es = 0.696; 95% ci, 0.407-0.986; p < 0.001; studies = 9), as well as reduced physiological response to noxious stimuli (es = 0.456; 95% ci, 0.131-0.783; p = 0.006) and pain intensity/unpleasantness ratings (es = 0.547; 95% ci, 0.146-0.949; p = 0.008). |
2016-07-20 |
2023-08-13 |
Not clear |
Yu-Chiau Shyu, Shin-Sheng Yuan, Sheng-Yu Lee, Chun-Ju Yang, Kang-Chung Yang, Tung-Liang Lee, Liang-Jen Wan. Attention-deficit/hyperactivity disorder, methylphenidate use and the risk of developing schizophrenia spectrum disorders: A nationwide population-based study in Taiwan. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26363968. |
compared to the control group, the adhd group showed significantly increased risk of developing any psychotic disorder (adjusted hazard ratio [ahr], 5.20; 95% confidence interval [ci], 4.30-6.30) and schizophrenia (ahr, 4.65; 95% ci, 3.59-6.04). |
2016-07-06 |
2023-08-13 |
human |
Yu-Chiau Shyu, Shin-Sheng Yuan, Sheng-Yu Lee, Chun-Ju Yang, Kang-Chung Yang, Tung-Liang Lee, Liang-Jen Wan. Attention-deficit/hyperactivity disorder, methylphenidate use and the risk of developing schizophrenia spectrum disorders: A nationwide population-based study in Taiwan. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26363968. |
among patients with adhd, mph use significantly increased the risk of developing any psychotic disorder (ahr, 1.20; 95% ci, 1.04-1.40), but did not increase the risk of developing schizophrenia (ahr, 1.16; 95% ci, 0.94-1.42). |
2016-07-06 |
2023-08-13 |
human |
Paolo Stagi, Simona Galeotti, Stefano Mimmi, Fabrizio Starace, Augusto C Castagnin. Continuity of care from child and adolescent to adult mental health services: evidence from a regional survey in Northern Italy. European child & adolescent psychiatry. vol 24. issue 12. 2016-06-27. PMID:26141538. |
young people referred for treatment to amhs were more likely to receive a discharge diagnosis of schizophrenia and related disorders (odds ratio [or] 3.92; 95 % confidence interval [ci] 2.17-7.08), personality disorders (or 2.69; 95 % ci 1.89-3.83), and pervasive developmental disorders (or 2.13; 95 % ci 1.51-2.99). |
2016-06-27 |
2023-08-13 |
Not clear |
Yueh-Han Hsu, Jur-Shan Cheng, Wen-Chen Ouyang, Chen-Li Lin, Chi-Ting Huang, Chih-Cheng Hs. Lower Incidence of End-Stage Renal Disease but Suboptimal Pre-Dialysis Renal Care in Schizophrenia: A 14-Year Nationwide Cohort Study. PloS one. vol 10. issue 10. 2016-06-14. PMID:26469976. |
compared to general population, patients with schizophrenia were less likely to develop esrd (hr = 0.6; 95% ci 0.4-0.8), but had a higher risk for death (hr = 1.2; 95% ci, 1.1-1.3). |
2016-06-14 |
2023-08-13 |
human |
Yueh-Han Hsu, Jur-Shan Cheng, Wen-Chen Ouyang, Chen-Li Lin, Chi-Ting Huang, Chih-Cheng Hs. Lower Incidence of End-Stage Renal Disease but Suboptimal Pre-Dialysis Renal Care in Schizophrenia: A 14-Year Nationwide Cohort Study. PloS one. vol 10. issue 10. 2016-06-14. PMID:26469976. |
patients with schizophrenia at the pre-esrd stage received suboptimal pre-dialysis renal care; for example, they were less likely to visit nephrologists (or = 0.6; 95% ci, 0.4-0.8) and received fewer erythropoietin prescriptions (or = 0.7; 95% ci, 0.6-0.9). |
2016-06-14 |
2023-08-13 |
human |
Hong Liang, Jørn Olsen, Wei Yuan, Sven Cnattingus, Mogens Vestergaard, Carsten Obel, Mika Gissler, Jiong L. Early Life Bereavement and Schizophrenia: A Nationwide Cohort Study in Denmark and Sweden. Medicine. vol 95. issue 3. 2016-06-09. PMID:26817875. |
compared with unexposed children, those exposed had overall a 39% higher risk of schizophrenia (= 1.39, 95% ci [confidence interval]: 1.32-1.47). |
2016-06-09 |
2023-08-13 |
Not clear |
Hong Liang, Jørn Olsen, Wei Yuan, Sven Cnattingus, Mogens Vestergaard, Carsten Obel, Mika Gissler, Jiong L. Early Life Bereavement and Schizophrenia: A Nationwide Cohort Study in Denmark and Sweden. Medicine. vol 95. issue 3. 2016-06-09. PMID:26817875. |
children who experienced >1 death during the first 18 years of life (airr = 1.79, 95% ci: 1.46-2.19) had a higher risk than those with a single death (airr = 1.37, 95% ci: 1.30-1.45).the study suggested that exposure to death of a first-degree relative before 18 years was associated with an increased risk of schizophrenia in later life. |
2016-06-09 |
2023-08-13 |
Not clear |