| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li-Ze Gu, Teng Jiang, Zao-Huo Cheng, Yue-Chun Zhang, Meng-Meng Ou, Min-Chi Chen, Zhen-He Zhou, Wei-Ming Lin. rs11098403 polymorphism near NDST3 is associated with a reduced risk of schizophrenia in a Han Chinese population. Neuroscience letters. vol 581. 2015-06-09. PMID:25139529. |
furthermore, this association was further confirmed using an independent replication sample containing 267 schizophrenia patients and 400 control subjects with a han chinese descent (or=0.652; 95% ci: 0.469-0.907; p=0.011; power=0.772). |
2015-06-09 |
2023-08-13 |
human |
| Katina Aleksovska, Emanuele Leoncini, Stefano Bonassi, Alfredo Cesario, Stefania Boccia, Alessandra Frustac. Systematic review and meta-analysis of circulating S100B blood levels in schizophrenia. PloS one. vol 9. issue 9. 2015-05-18. PMID:25202915. |
schizophrenia patients showed 76% higher s100b blood levels than controls with mmr = 1.76 95% ci: 1.44-2.15. |
2015-05-18 |
2023-08-13 |
Not clear |
| Meiyan Zhu, Tongyang Liu, Jihong Zhang, Shuting Jia, Wenru Tang, Ying Lu. Association between rs1344706 of ZNF804A and schizophrenia: a meta-analysis. Genomics, proteomics & bioinformatics. vol 12. issue 6. 2015-05-07. PMID:25526981. |
the current meta-analysis showed an association between rs1344706 and schizophrenia in caucasian populations (p=0.028, or=1.138, 95% ci: 1.014-1.278; p=0.004 for heterogeneity) and asian populations (p=0.008, or=1.092, 95% ci: 1.023-1.165; p=0.001 for heterogeneity), but not in other populations (p=0.286, or=1.209, 95% ci: 0.853-1.714, p=0.120 for heterogeneity). |
2015-05-07 |
2023-08-13 |
human |
| Holger J Sørensen, Philip R Nielsen, Carsten B Pedersen, Michael E Benros, Merete Nordentoft, Preben B Mortense. Population impact of familial and environmental risk factors for schizophrenia: a nationwide study. Schizophrenia research. vol 153. issue 1-3. 2015-04-22. PMID:24440494. |
cumulative incidences for male offspring or female offspring of a parent with schizophrenia were 9.53% (95% ci=7.71-11.79), and 4.89%, (95% ci 4.50-5.31). |
2015-04-22 |
2023-08-12 |
Not clear |
| Sudhakar Selvaraj, Danilo Arnone, Alessandra Cappai, Oliver Howe. Alterations in the serotonin system in schizophrenia: a systematic review and meta-analysis of postmortem and molecular imaging studies. Neuroscience and biobehavioral reviews. vol 45. 2015-04-16. PMID:24971825. |
meta-analysis of postmortem studies found an elevation in prefrontal 5-ht1a receptors with a moderate to large effect size (n=8, 85 patients and 94 controls, smd=0.60; ci: 0.17-1.03; p=0.007) and a reduction with a large effect size in prefrontal 5-ht2a receptors (n=8, 168 patients and 163 controls, smd=-0.73; ci: -1.33, -0.12; p=0.019) in schizophrenia vs healthy controls. |
2015-04-16 |
2023-08-13 |
Not clear |
| Derek W Morris, Richard D Pearson, Paul Cormican, Elaine M Kenny, Colm T O'Dushlaine, Louis-Philippe Lemieux Perreault, Eleni Giannoulatou, Daniela Tropea, Brion S Maher, Brandon Wormley, Eric Kelleher, Ciara Fahey, Ines Molinos, Stefania Bellini, Matti Pirinen, Amy Strange, Colin Freeman, Dawn L Thiselton, Rachel L Elves, Regina Regan, Sean Ennis, Timothy G Dinan, Colm McDonald, Kieran C Murphy, Eadbhard O'Callaghan, John L Waddington, Dermot Walsh, Michael O'Donovan, Detelina Grozeva, Nick Craddock, Jennifer Stone, Ed Scolnick, Shaun Purcell, Pamela Sklar, Bradley Coe, Evan E Eichler, Roel Ophoff, Jacobine Buizer, Jin Szatkiewicz, Christina Hultman, Patrick Sullivan, Hugh Gurling, Andrew Mcquillin, David St Clair, Elliott Rees, George Kirov, James Walters, Douglas Blackwood, Mandy Johnstone, Gary Donohoe, Francis A O'Neill, Kenneth S Kendler, Michael Gill, Brien P Riley, Chris C A Spencer, Aiden Corvi. An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis. Human molecular genetics. vol 23. issue 12. 2015-01-12. PMID:24474471. |
a combined analysis of irish/uk subjects including additional psychosis cases (schizophrenia and bipolar disorder) identified 22 carriers in 11 707 cases and 10 carriers in 21 204 controls [meta-analysis cochran-mantel-haenszel p-value = 2 × 10(-4); odds ratio (or) = 11.3, 95% ci = 3.7, ∞]. |
2015-01-12 |
2023-08-12 |
human |
| Su Kang Kim, Hae Jeong Park, Hosik Seok, Hye Sook Jeon, Joo-Ho Chung, Won Sub Kang, Jong Woo Kim, Gyeong Im Yu, Dong Hoon Shi. Association study between monoamine oxidase A (MAOA) gene polymorphisms and schizophrenia: lack of association with schizophrenia and possible association with affective disturbances of schizophrenia. Molecular biology reports. vol 41. issue 5. 2015-01-05. PMID:24510409. |
in the analysis of the common clinical symptoms of schizophrenia patients, three examined snps were associated with affective disturbances, especially restricted affect and blunted affect in male schizophrenia, respectively (restricted affect, p=0.002, or=2.71, 95% ci 1.45-5.00; blunted affect, p=0.009, or 2.25, 95% ci 1.22-4.12). |
2015-01-05 |
2023-08-12 |
human |
| James D Clelland, Laura L Read, Valérie Drouet, Angela Kaon, Alexandra Kelly, Karen E Duff, Robert H Nadrich, Amit Rajparia, Catherine L Clellan. Vitamin D insufficiency and schizophrenia risk: evaluation of hyperprolinemia as a mediator of association. Schizophrenia research. vol 156. issue 1. 2014-12-22. PMID:24787057. |
25(oh)d levels were significantly lower in patients, and 25(oh)d insufficiency associated with schizophrenia (or 2.1, adjusted p=0.044, 95% ci: 1.02-4.46). |
2014-12-22 |
2023-08-13 |
human |
| James D Clelland, Laura L Read, Valérie Drouet, Angela Kaon, Alexandra Kelly, Karen E Duff, Robert H Nadrich, Amit Rajparia, Catherine L Clellan. Vitamin D insufficiency and schizophrenia risk: evaluation of hyperprolinemia as a mediator of association. Schizophrenia research. vol 156. issue 1. 2014-12-22. PMID:24787057. |
moreover, 25(oh)d insufficient subjects had three times greater odds of hyperprolinemia than those with optimal levels (p=0.035, 95% ci: 1.08-8.91), and formal testing established that hyperprolinemia is a significantly mediating phenotype that may explain over a third of the effect of 25(oh)d insufficiency on schizophrenia risk. |
2014-12-22 |
2023-08-13 |
human |
| Marie-Hélène Lafeuille, Jason Dean, John Fastenau, Jessica Panish, William Olson, Michael Markowitz, Mei Sheng Duh, Patrick Lefebvr. Burden of schizophrenia on selected comorbidity costs. Expert review of pharmacoeconomics & outcomes research. vol 14. issue 2. 2014-12-17. PMID:24593801. |
patients with schizophrenia incurred greater all-cause monthly healthcare costs (cost difference [95% ci]: us$978 [933; 1024]) and comorbidity-related costs (cost difference [95% ci]: us$288 [269; 307]). |
2014-12-17 |
2023-08-12 |
Not clear |
| Kuanjun He, Qingzhong Wang, Jianhua Chen, Tao Li, Zhiqiang Li, Wenjin Li, Zujia Wen, Yu Qiang, Meng Wang, Jiawei Shen, Zhijian Song, Jue Ji, Guoyin Feng, Shuguang Qi, He Lin, Yongyong Shi, Zaohuo Chen. ITIH family genes confer risk to schizophrenia and major depressive disorder in the Han Chinese population. Progress in neuro-psychopharmacology & biological psychiatry. vol 51. 2014-11-25. PMID:24389398. |
we found that rs2710322 was significantly associated with schizophrenia (adjusted p(allele) = 0.0018, adjusted p(genotype) = 0.006, or [95% ci] = 1.278 [1.117-1.462]) while rs1042779 was weakly associated with schizophrenia (adjusted p(allele) = 0.048, or [95% ci] = 1.164 [1.040-1.303]) and major depressive disorder (adjusted p(allele) = 0.042, or [95% ci] = 1.178 [1.047-1.326]); it was also our finding that rs3821831 was positively associated with major depressive disorder (adjusted p(allele) = 0.003, adjusted p(genotype) = 0.006, or [95% ci] = 1.426 [1.156-1.760]). |
2014-11-25 |
2023-08-12 |
human |
| Kuanjun He, Qingzhong Wang, Jianhua Chen, Tao Li, Zhiqiang Li, Wenjin Li, Zujia Wen, Yu Qiang, Meng Wang, Jiawei Shen, Zhijian Song, Jue Ji, Guoyin Feng, Shuguang Qi, He Lin, Yongyong Shi, Zaohuo Chen. ITIH family genes confer risk to schizophrenia and major depressive disorder in the Han Chinese population. Progress in neuro-psychopharmacology & biological psychiatry. vol 51. 2014-11-25. PMID:24389398. |
via the association analysis which combines the schizophrenia and major depressive disorder cases, we also notice that rs1042779 and rs3821831 were significantly associated with combined cases (rs1042779: adjusted p(allele) = 0.012, adjusted p(genotype) = 0.018, or [95% ci] = 1.171 [1.060-1.292]; rs3821831:adjusted p(genotype) = 0.012, or [95% ci] = 1.193 [1.010-1.410]). |
2014-11-25 |
2023-08-12 |
human |
| Steven M Lilly, Eric M Mortensen, Christopher R Frei, Mary Jo Pugh, Ishak A Mans. Comparison of the risk of psychological and cognitive disorders between persistent and nonpersistent statin users. The American journal of cardiology. vol 114. issue 7. 2014-11-13. PMID:25212545. |
they were also more likely to be diagnosed with schizophrenia or psychosis (odds ratio [or] 1.58, 95% confidence interval [ci] 1.20 to 2.10) and cognitive disorders (or 1.56, 95% ci 1.19 to 2.03) during follow-up compared with persistent users. |
2014-11-13 |
2023-08-13 |
Not clear |
| Daimei Sasayama, Hiroaki Hori, Noriko Yamamoto, Seiji Nakamura, Toshiya Teraishi, Masahiko Tatsumi, Kotaro Hattori, Miho Ota, Teruhiko Higuchi, Hiroshi Kunug. ITIH3 polymorphism may confer susceptibility to psychiatric disorders by altering the expression levels of GLT8D1. Journal of psychiatric research. vol 50. 2014-10-06. PMID:24373612. |
a significant difference in allele distribution was found between patients with schizophrenia and controls (odds ratio [or] = 1.21, 95% confidence interval [ci]: 1.05-1.39, p = 0.0077). |
2014-10-06 |
2023-08-12 |
human |
| Daimei Sasayama, Hiroaki Hori, Noriko Yamamoto, Seiji Nakamura, Toshiya Teraishi, Masahiko Tatsumi, Kotaro Hattori, Miho Ota, Teruhiko Higuchi, Hiroshi Kunug. ITIH3 polymorphism may confer susceptibility to psychiatric disorders by altering the expression levels of GLT8D1. Journal of psychiatric research. vol 50. 2014-10-06. PMID:24373612. |
the allele distribution in the combined patient group (schizophrenia and mdd) was significantly different from that of the control group (or = 1.15, 95% ci: 1.03-1.28, p = 0.011). |
2014-10-06 |
2023-08-12 |
human |
| Fanfan Zheng, Yanling Zhang, Wuxiang Xie, Wenqiang Li, Chao Jin, Weifeng Mi, Fang Wang, Wenbin Ma, Cuicui Ma, Yongfeng Yang, Bo Du, Keqing Li, Chenxing Liu, Lifang Wang, Tianlan Lu, Hongyan Zhang, Yun Wang, Lin Lu, Luxian Lv, Dai Zhang, Weihua Yu. Further evidence for genetic association of CACNA1C and schizophrenia: new risk loci in a Han Chinese population and a meta-analysis. Schizophrenia research. vol 152. issue 1. 2014-08-29. PMID:24355530. |
in the meta-analysis, the association between rs1006737 and schizophrenia remained significant (or=1.14, 95% ci: 1.07-1.22, p=0.0001). |
2014-08-29 |
2023-08-12 |
human |
| Yuqing Pan, Jun Yao, Baojie Wan. Association of dopamine D1 receptor gene polymorphism with schizophrenia: a meta-analysis. Neuropsychiatric disease and treatment. vol 10. 2014-07-14. PMID:25018632. |
for the rs5326 locus, the guanine-adenine (ga) genotype was associated with schizophrenia as a risk factor (for ga vs guanine-guanine [gg], odds ratio [or] =1.36, 95% confidence interval [ci]: 1.15-1.61, p<0.001). |
2014-07-14 |
2023-08-13 |
Not clear |
| Philip Rising Nielsen, Preben Bo Mortensen, Christina Dalman, Tine Brink Henriksen, Marianne Giørtz Pedersen, Carsten Bøcker Pedersen, Esben Agerb. Fetal growth and schizophrenia: a nested case-control and case-sibling study. Schizophrenia bulletin. vol 39. issue 6. 2014-06-23. PMID:23236080. |
sga was associated with an irr of 1.23 (95% ci: 1.11-1.37) for schizophrenia in the case-control study. |
2014-06-23 |
2023-08-12 |
Not clear |
| Todd Lencz, Saurav Guha, Chunyu Liu, Jeffrey Rosenfeld, Semanti Mukherjee, Pamela DeRosse, Majnu John, Lijun Cheng, Chunling Zhang, Judith A Badner, Masashi Ikeda, Nakao Iwata, Sven Cichon, Marcella Rietschel, Markus M Nöthen, A T A Cheng, Colin Hodgkinson, Qiaoping Yuan, John M Kane, Annette T Lee, Anne Pisanté, Peter K Gregersen, Itsik Pe'er, Anil K Malhotra, David Goldman, Ariel Darvas. Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder. Nature communications. vol 4. 2014-06-19. PMID:24253340. |
the top single-nucleotide polymorphism (snp; rs11098403) demonstrates consistent effects across 11 replication and extension cohorts, totalling 23, 191 samples across multiple ethnicities, regardless of diagnosis (schizophrenia or bipolar disorder), resulting in pmeta=9.49 × 10(-12) (odds ratio (or)=1.13, 95% confidence interval (ci): 1.08-1.17) across both disorders and pmeta=2.67 × 10(-8) (or=1.15, 95% ci: 1.08-1.21) for schizophrenia alone. |
2014-06-19 |
2023-08-12 |
Not clear |
| Mohd A Zain, Siti N Roffeei, Nor Z Zainal, Sharmilla Kanagasundram, Zahurin Mohame. Nonsynonymous polymorphisms of the PDLIM5 gene association with the occurrence of both bipolar disorder and schizophrenia. Psychiatric genetics. vol 23. issue 6. 2014-06-12. PMID:24064681. |
a significant association was also observed between the rs7690296 polymorphism and schizophrenia under the recessive model for both malay (p=0.02, adjusted or 1.86, 95% ci 1.12-3.10) and indian (p=0.02, adjusted or 1.92, 95% ci 1.10-3.37) ethnic groups. |
2014-06-12 |
2023-08-12 |
Not clear |