| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Heaji Lee, Sun Yeou Kim, Yunsook Li. Lespedeza bicolor extract supplementation reduced hyperglycemia-induced skeletal muscle damage by regulation of AMPK/SIRT/PGC1α-related energy metabolism in type 2 diabetic mice. Nutrition research (New York, N.Y.). vol 110. 2023-01-13. PMID:36638746. |
inflammation and oxidative stress caused by type 2 diabetes mellitus (t2dm) not only contributes to insulin resistance, but also promotes muscle atrophy via decreased muscle protein synthesis and increased protein degradation, leading to frailty and sarcopenia. |
2023-01-13 |
2023-08-14 |
mouse |
| Toshiaki Seko, Hiroshi Akasaka, Masayuki Koyama, Nobuaki Himuro, Shigeyuki Saitoh, Tetsuji Miura, Mitsuru Mori, Hirofumi Ohnish. Preserved Lower Limb Muscle Mass Prevents Insulin Resistance Development in Nondiabetic Older Adults. Journal of the American Medical Directors Association. 2023-01-02. PMID:36592939. |
to investigate roles of sarcopenia indexes in prediction of development of insulin resistance in nondiabetic older adults. |
2023-01-02 |
2023-08-14 |
Not clear |
| Yanxia Lu, Wee Shiong Lim, Xia Jin, Ma Schwe Zin Nyunt, Tamas Fulop, Qi Gao, Su Chi Lim, Anis Larbi, Tze Pin N. Lower insulin level is associated with sarcopenia in community-dwelling frail and non-frail older adults. Frontiers in medicine. vol 9. 2022-12-09. PMID:36482911. |
lower insulin level is associated with sarcopenia in community-dwelling frail and non-frail older adults. |
2022-12-09 |
2023-08-14 |
Not clear |
| Yanxia Lu, Wee Shiong Lim, Xia Jin, Ma Schwe Zin Nyunt, Tamas Fulop, Qi Gao, Su Chi Lim, Anis Larbi, Tze Pin N. Lower insulin level is associated with sarcopenia in community-dwelling frail and non-frail older adults. Frontiers in medicine. vol 9. 2022-12-09. PMID:36482911. |
there are conflicting evidence in support of the role of insulin in the development of age-related and t2dm-related sarcopenia. |
2022-12-09 |
2023-08-14 |
Not clear |
| Yanxia Lu, Wee Shiong Lim, Xia Jin, Ma Schwe Zin Nyunt, Tamas Fulop, Qi Gao, Su Chi Lim, Anis Larbi, Tze Pin N. Lower insulin level is associated with sarcopenia in community-dwelling frail and non-frail older adults. Frontiers in medicine. vol 9. 2022-12-09. PMID:36482911. |
we investigated the relationships between the levels of fasting insulin and other blood biomarkers related to insulin or lipid metabolism with the presence of sarcopenia in two independent studies. |
2022-12-09 |
2023-08-14 |
Not clear |
| Sae Kyung Joo, Won Ki. Interaction between Sarcopenia and NAFLD. Clinical and molecular hepatology. 2022-12-06. PMID:36472051. |
sarcopenia and nafld are linked by several shared pathogenetic mechanisms, including insulin resistance, hormonal imbalance, systemic inflammation, myostatin and adiponectin dysregulation, nutritional deficiencies, and physical inactivity, thus implicating a bidirectional relationship between sarcopenia and nafld. |
2022-12-06 |
2023-08-14 |
Not clear |
| Mengting Yin, He Zhang, Qianhui Liu, Fei Ding, Lisha Hou, Yiping Deng, Tao Cui, Yixian Han, Yijun Chen, Chen Huang, Jirong Yue, Yong H. Determination of skeletal muscle mass by aspartate aminotransferase / alanine aminotransferase ratio, insulin and FSH in Chinese women with sarcopenia. BMC geriatrics. vol 22. issue 1. 2022-11-24. PMID:36419004. |
determination of skeletal muscle mass by aspartate aminotransferase / alanine aminotransferase ratio, insulin and fsh in chinese women with sarcopenia. |
2022-11-24 |
2023-08-14 |
Not clear |
| Hun Jee Choe, Hyunsuk Lee, DongHo Lee, Soo-Heon Kwak, Bo Kyung Ko. Different effects of low muscle mass on the risk of non-alcoholic fatty liver disease and hepatic fibrosis in a prospective cohort. Journal of cachexia, sarcopenia and muscle. 2022-11-20. PMID:36403577. |
non-alcoholic fatty liver disease (nafld) and sarcopenia share insulin resistance as a common pathophysiology and have overlapping clinical manifestation of metabolic derangement; hence, it is difficult to differentiate the independent effect of sarcopenia on the development of nafld from concomitant metabolic disorders. |
2022-11-20 |
2023-08-14 |
Not clear |
| Ramesh Kumar, Sabbu Surya Prakash, Rajeev Nayan Priyadarshi, Utpal Anan. Sarcopenia in Chronic Liver Disease: A Metabolic Perspective. Journal of clinical and translational hepatology. vol 10. issue 6. 2022-11-16. PMID:36381104. |
a major contributor to sarcopenia in cld is the imbalance in muscle protein turnover wherein changes in various metabolic factors such as hyperammonemia, amino acid deprivation, hormonal imbalance, gut dysbiosis, insulin resistance, chronic inflammation, etc. |
2022-11-16 |
2023-08-14 |
Not clear |
| Ramesh Kumar, Sabbu Surya Prakash, Rajeev Nayan Priyadarshi, Utpal Anan. Sarcopenia in Chronic Liver Disease: A Metabolic Perspective. Journal of clinical and translational hepatology. vol 10. issue 6. 2022-11-16. PMID:36381104. |
skeletal muscle is a major organ of insulin-induced glucose metabolism, and sarcopenia is closely linked to insulin resistance and metabolic syndrome. |
2022-11-16 |
2023-08-14 |
Not clear |
| Dyah Purnamasari, Erpryta Nurdia Tetrasiwi, Gracia Jovita Kartiko, Cindy Astrella, Khoirul Husam, Purwita Wijaya Laksm. Sarcopenia and Chronic Complications of Type 2 Diabetes Mellitus. The review of diabetic studies : RDS. vol 18. issue 3. 2022-10-30. PMID:36309772. |
insulin resistance that exists in t2dm is thought to be the key mediator for impaired physical function and mobility which may lead to sarcopenia. |
2022-10-30 |
2023-08-14 |
Not clear |
| Dyah Purnamasari, Erpryta Nurdia Tetrasiwi, Gracia Jovita Kartiko, Cindy Astrella, Khoirul Husam, Purwita Wijaya Laksm. Sarcopenia and Chronic Complications of Type 2 Diabetes Mellitus. The review of diabetic studies : RDS. vol 18. issue 3. 2022-10-30. PMID:36309772. |
t2dm may cause sarcopenia through the mediation of insulin resistance, inflammation, accumulation of advanced glycation end-products, and oxidative stress that may affect muscle mass and strength, protein metabolism, and vascular and mitochondrial dysfunction. |
2022-10-30 |
2023-08-14 |
Not clear |
| Takayoshi Sasako, Toshihiro Umehara, Kotaro Soeda, Kazuma Kaneko, Miho Suzuki, Naoki Kobayashi, Yukiko Okazaki, Miwa Tamura-Nakano, Tomoki Chiba, Domenico Accili, C Ronald Kahn, Tetsuo Noda, Hiroshi Asahara, Toshimasa Yamauchi, Takashi Kadowaki, Kohjiro Uek. Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice. Nature communications. vol 13. issue 1. 2022-10-05. PMID:36198696. |
here we show that mice with skeletal muscle-specific double knockout of akt1/2, key downstream molecules of insulin signaling, serve as a model of premature sarcopenia with insulin resistance. |
2022-10-05 |
2023-08-14 |
mouse |
| Ruoxin Chen, Liuping Zhang, Mengyan Zhang, Ying Wang, Dan Liu, Zuolin Li, Xiaoliang Zhang, Hui Jin, Bicheng Liu, Hong Li. The triglyceride-glucose index as a novel marker associated with sarcopenia in non-diabetic patients on maintenance hemodialysis. Renal failure. vol 44. issue 1. 2022-10-03. PMID:36191303. |
insulin resistance is present in non-diabetic patients undergoing maintenance hemodialysis (mhd) and is an important factor leading to sarcopenia. |
2022-10-03 |
2023-08-14 |
Not clear |
| Katarzyna Romejko, Aleksandra Rymarz, Hanna Sadownik, Stanisław Niemczy. Testosterone Deficiency as One of the Major Endocrine Disorders in Chronic Kidney Disease. Nutrients. vol 14. issue 16. 2022-08-26. PMID:36014945. |
the implications of hypogonadism in ckd are infertility and loss of libido, reduction of muscle mass and strength, disorders in bone mineralization, the development of sarcopenia and protein energy wasting (pew), progression of atherosclerosis, increased visceral adiposity, insulin resistance, and anaemia. |
2022-08-26 |
2023-08-14 |
Not clear |
| Mohammad Bagherniya, Atena Mahdavi, Nafiseh Shokri-Mashhadi, Maciej Banach, Stephan Von Haehling, Thomas P Johnston, Amirhossein Sahebka. The beneficial therapeutic effects of plant-derived natural products for the treatment of sarcopenia. Journal of cachexia, sarcopenia and muscle. 2022-08-12. PMID:35961944. |
we found that several risk factors such as nutritional status, physical inactivity, inflammation, oxidative stress, endocrine system dysfunction, insulin resistance, history of chronic disease, mental health, and genetic factors are linked or associated with sarcopenia. |
2022-08-12 |
2023-08-14 |
human |
| Joseph S Redman, Matt Kaspar, Puneet Pur. Implications of pre-transplant sarcopenia and frailty in patients with non-alcoholic steatohepatitis and alcoholic liver disease. Translational gastroenterology and hepatology. vol 7. 2022-07-27. PMID:35892054. |
the metabolic syndrome worsens sarcopenia through multi-tissue insulin resistance. |
2022-07-27 |
2023-08-14 |
Not clear |
| Mohammad Shafi Kuchay, José Ignacio Martínez-Montoro, Parjeet Kaur, José Carlos Fernández-García, Bruno Ramos-Molin. Non-alcoholic fatty liver disease-related fibrosis and sarcopenia: an altered liver-muscle crosstalk leading to increased mortality risk. Ageing research reviews. 2022-07-17. PMID:35843589. |
remarkably, while sarcopenia and nafld-related fibrosis are independently associated with all-cause mortality, the combination of both conditions entails a greater risk for all-cause and cardiac-specific mortality.interestingly, both sarcopenia and nafld-related fibrosis share common pathophysiological pathways, including insulin resistance, chronic inflammation, hyperammonemia, alterations in the regulation of myokines, sex hormones and growth hormone/insulin-like growth factor-1 signaling, which may explain reciprocal connections between these two disorders. |
2022-07-17 |
2023-08-14 |
Not clear |
| Eugene Han, Mi Kyung Kim, Seung-Soon Im, Byoung Kuk Jang, Hye Soon Ki. Non-alcoholic fatty liver disease and sarcopenia is associated with the risk of albuminuria independent of insulin resistance, and obesity. Journal of diabetes and its complications. 2022-07-11. PMID:35817677. |
non-alcoholic fatty liver disease and sarcopenia is associated with the risk of albuminuria independent of insulin resistance, and obesity. |
2022-07-11 |
2023-08-14 |
Not clear |
| Yoshihisa Hiromine, Shinsuke Noso, Hiromi Rakugi, Ken Sugimoto, Yasunori Takata, Tomohiro Katsuya, Masahiro Fukuda, Hiroshi Akasaka, Haruhiko Osawa, Yasuharu Tabara, Hiroshi Ikegam. Poor glycemic control rather than types of diabetes is a risk factor for sarcopenia in diabetes mellitus: The MUSCLES-DM study. Journal of diabetes investigation. 2022-07-07. PMID:35796583. |
poor glycemic control and insulin treatment are reported to be associated with sarcopenia in type 2 diabetes, type 1 diabetes may be a stronger risk for sarcopenia. |
2022-07-07 |
2023-08-14 |
Not clear |