Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ligia J Dominguez, Mario Barbagall. The cardiometabolic syndrome and sarcopenic obesity in older persons. Journal of the cardiometabolic syndrome. vol 2. issue 3. 2007-12-06. PMID:17786082. |
cms is further complicated by modifications in body composition and fat redistribution during aging; older adults are at higher risk for developing central obesity and sarcopenia or sarcopenic obesity, a condition characterized by an important reduction in lean body mass associated with obesity, linked to an increased production of inflammatory adipokines that may alter insulin sensitivity and muscle mass and strength. |
2007-12-06 |
2023-08-12 |
Not clear |
Eric D B Goulet, Christine Lord, Jean-Philippe Chaput, Mylène Aubertin-Leheudre, Martin Brochu, Isabelle J Dionn. No difference in insulin sensitivity between healthy postmenopausal women with or without sarcopenia: a pilot study. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 32. issue 3. 2007-08-30. PMID:17510677. |
no difference in insulin sensitivity between healthy postmenopausal women with or without sarcopenia: a pilot study. |
2007-08-30 |
2023-08-12 |
Not clear |
Eric D B Goulet, Christine Lord, Jean-Philippe Chaput, Mylène Aubertin-Leheudre, Martin Brochu, Isabelle J Dionn. No difference in insulin sensitivity between healthy postmenopausal women with or without sarcopenia: a pilot study. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 32. issue 3. 2007-08-30. PMID:17510677. |
the age-associated decline in insulin sensitivity (is) may negatively alter muscle protein metabolism and, therefore, be implicated in the aetiology of sarcopenia. |
2007-08-30 |
2023-08-12 |
Not clear |
Eric D B Goulet, Christine Lord, Jean-Philippe Chaput, Mylène Aubertin-Leheudre, Martin Brochu, Isabelle J Dionn. No difference in insulin sensitivity between healthy postmenopausal women with or without sarcopenia: a pilot study. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 32. issue 3. 2007-08-30. PMID:17510677. |
using quicki, a surrogate measure of is, the present results suggest that the action of insulin does not play an important role in the development and maintenance of sarcopenia in healthy, non-obese, postmenopausal women. |
2007-08-30 |
2023-08-12 |
Not clear |
A J O'Sullivan, J J Kell. Insulin resistance and protein catabolism in non-diabetic hemodialysis patients. Kidney international. vol 71. issue 2. 2007-04-03. PMID:17213856. |
if insulin resistance is implicated in sarcopenia of ckd, further research will be required to determine whether interventions that improve insulin sensitivity improve clinical outcomes and cardiovascular risk in ckd. |
2007-04-03 |
2023-08-12 |
Not clear |
Flemming Dela, Michael Kjae. Resistance training, insulin sensitivity and muscle function in the elderly. Essays in biochemistry. vol 42. 2007-02-20. PMID:17144881. |
this leads to sarcopenia and reduced daily function, as well as to an increased risk for development of insulin resistance and type 2 diabetes. |
2007-02-20 |
2023-08-12 |
Not clear |
Blake B Rasmussen, Satoshi Fujita, Robert R Wolfe, Bettina Mittendorfer, Mona Roy, Vincent L Rowe, Elena Volp. Insulin resistance of muscle protein metabolism in aging. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 6. 2006-05-08. PMID:16464955. |
in conclusion, skeletal muscle protein synthesis is resistant to the anabolic action of insulin in older subjects, which may be an important contributor to the development of sarcopenia. |
2006-05-08 |
2023-08-12 |
human |
C Guillet, Y Boiri. Insulin resistance: a contributing factor to age-related muscle mass loss? Diabetes & metabolism. vol 31 Spec No 2. 2006-05-02. PMID:16415762. |
however, the effect of insulin on protein metabolism is less well documented, and insulin resistance could be involved in age-related muscle protein loss, progressively leading to sarcopenia. |
2006-05-02 |
2023-08-12 |
human |
Helen Karakelides, K Sreekumaran Nai. Sarcopenia of aging and its metabolic impact. Current topics in developmental biology. vol 68. 2005-09-29. PMID:16124998. |
the metabolic effects of sarcopenia include a decrease in resting metabolic rate secondary to decreased fat-free mass and decreased physical activity, leading to a higher prevalence of insulin resistance, type 2 diabetes mellitus, dyslipidemia, and hypertension. |
2005-09-29 |
2023-08-12 |
Not clear |
Michael R Deschene. Effects of aging on muscle fibre type and size. Sports medicine (Auckland, N.Z.). vol 34. issue 12. 2005-02-10. PMID:15462613. |
moreover, sarcopenia has been linked to several chronic afflictions that are common among the aged, including osteoporosis, insulin resistance and arthritis. |
2005-02-10 |
2023-08-12 |
Not clear |
B Beaufrère, B Mori. Fat and protein redistribution with aging: metabolic considerations. European journal of clinical nutrition. vol 54 Suppl 3. 2001-10-04. PMID:11041075. |
independent and significant effects of menopause or of sarcopenia on insulin resistance remain to be established. |
2001-10-04 |
2023-08-12 |
Not clear |
B F Hurley, S M Rot. Strength training in the elderly: effects on risk factors for age-related diseases. Sports medicine (Auckland, N.Z.). vol 30. issue 4. 2001-02-02. PMID:11048773. |
collectively, these studies indicate that st in the elderly: (i) is an effective intervention against sarcopenia because it produces substantial increases in the strength, mass, power and quality of skeletal muscle; (ii) can increase endurance performance; (iii) normalises blood pressure in those with high normal values; (iv) reduces insulin resistance; (v) decreases both total and intra-abdominal fat; (vi) increases resting metabolic rate in older men; (vii) prevents the loss of bmd with age; (viii) reduces risk factors for falls; and (ix) may reduce pain and improve function in those with osteoarthritis in the knee region. |
2001-02-02 |
2023-08-12 |
Not clear |
S B Eaton, S B Eato. Paleolithic vs. modern diets--selected pathophysiological implications. European journal of nutrition. vol 39. issue 2. 2000-11-30. PMID:10918987. |
this review addresses phytochemicals and cancer; calcium, physical exertion, bone mineral density and bone structural geometry; dietary protein, potassium, renal acid secretion and urinary calcium loss; and finally sarcopenia, adiposity, insulin receptors and insulin resistance. |
2000-11-30 |
2023-08-12 |
Not clear |