| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Munar-Qués, J L Pedrosa, T Coelho, L Gusmão, R Seruca, A Amorim, J Sequeiro. Two pairs of proven monozygotic twins discordant for familial amyloid neuropathy (FAP) TTR Met 30. Journal of medical genetics. vol 36. issue 8. 1999-09-27. PMID:10465115. |
familial amyloidotic polyneuropathy type i (fap-i), ttr met 30, was present in two sets of proven monozygotic (mz) twins, one from majorca and the other from portugal. |
1999-09-27 |
2023-08-12 |
Not clear |
| M Nakamura, T Yamashita, Y Ando, K Hamidi Asl, K Tashima, P Ohlsson, Y Kususe, M D Benso. Identification of a new transthyretin variant (Ile49) in familial amyloidotic polyneuropathy using electrospray ionization mass spectrometry and nonisotopic RNase cleavage assay. Human heredity. vol 49. issue 4. 1999-09-21. PMID:10436378. |
mutation of the transthyretin (ttr) plasma protein and gene in a japanese patient with amyloid polyneuropathy was investigated by electrospray ionization mass spectrometry (esi-ms) and nonisotopic rnase cleavage assay (nirca), respectively. |
1999-09-21 |
2023-08-12 |
Not clear |
| Y Ando, M Almeida, P I Ohlsson, E Ando, A Negi, O Suhr, H Terazaki, K Obayashi, M Ando, M J Saraiv. Unusual self-association properties of transthyretin Y114C related to familial amyloidotic polyneuropathy: effects on detection and quantification. Biochemical and biophysical research communications. vol 261. issue 2. 1999-09-08. PMID:10425176. |
we performed biochemical and immunological examinations of heterozygotic carriers of the transthyretin (ttr) mutant y114c associated with familial amyloidotic polyneuropathy (fap). |
1999-09-08 |
2023-08-12 |
Not clear |
| I Beirão, L Lobato, S Riedstra, P M Costa, S Pimentel, S Guimarãe. Ineffectiveness of dialysis in transthyretin (TTR) clearance in familial amyloid polyneuropathy type I, in spite of lower stability of the TTR Met30 variant. Clinical nephrology. vol 51. issue 1. 1999-04-16. PMID:9988146. |
ineffectiveness of dialysis in transthyretin (ttr) clearance in familial amyloid polyneuropathy type i, in spite of lower stability of the ttr met30 variant. |
1999-04-16 |
2023-08-12 |
Not clear |
| I Beirão, L Lobato, S Riedstra, P M Costa, S Pimentel, S Guimarãe. Ineffectiveness of dialysis in transthyretin (TTR) clearance in familial amyloid polyneuropathy type I, in spite of lower stability of the TTR Met30 variant. Clinical nephrology. vol 51. issue 1. 1999-04-16. PMID:9988146. |
familial amyloid polyneuropathy (fap) is an hereditary form of systemic amyloidosis related to a mutant transthyretin (ttr). |
1999-04-16 |
2023-08-12 |
Not clear |
| M Brett, M R Persey, M M Reilly, T Revesz, D R Booth, S E Booth, P N Hawkins, M B Pepys, J A Morgan-Hughe. Transthyretin Leu12Pro is associated with systemic, neuropathic and leptomeningeal amyloidosis. Brain : a journal of neurology. vol 122 ( Pt 2). 1999-03-18. PMID:10071047. |
she had extensive amyloid deposition in the leptomeninges and liver as well as the involvement of the heart and peripheral nervous system which characterizes familial amyloid polyneuropathy caused by variant ttr. |
1999-03-18 |
2023-08-12 |
Not clear |
| H A Lashuel, Z Lai, J W Kell. Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation. Biochemistry. vol 37. issue 51. 1999-02-11. PMID:9922152. |
analytical ultracentrifugation methods were utilized to further characterize the acid denaturation pathways of wild-type, v30m, and l55p transthyretin (ttr) that generate intermediates leading to amyloid fibril formation and possibly the diseases senile systemic amyloidosis and familial amyloid polyneuropathy. |
1999-02-11 |
2023-08-12 |
Not clear |
| H A Lashuel, Z Lai, J W Kell. Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation. Biochemistry. vol 37. issue 51. 1999-02-11. PMID:9922152. |
interestingly, the l55p and v30m familial amyloid polyneuropathy (fap) associated variants form amyloid protofilaments at ph 7.5 (37 degrees c) after several weeks of incubation, suggesting that the activation barriers for ttr tetramer dissociation to the monomeric amyloidogenic intermediate are much lower for the fap variants relative to wild-type ttr, which does not form amyloid or amyloid protofilaments under these conditions. |
1999-02-11 |
2023-08-12 |
Not clear |
| H Inouye, F S Domingues, A M Damas, M J Saraiva, E Lundgren, O Sandgren, D A Kirschne. Analysis of x-ray diffraction patterns from amyloid of biopsied vitreous humor and kidney of transthyretin (TTR) Met30 familial amyloidotic polyneuropathy (FAP) patients: axially arrayed TTR monomers constitute the protofilament. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 5. issue 3. 1999-01-15. PMID:9818053. |
analysis of x-ray diffraction patterns from amyloid of biopsied vitreous humor and kidney of transthyretin (ttr) met30 familial amyloidotic polyneuropathy (fap) patients: axially arrayed ttr monomers constitute the protofilament. |
1999-01-15 |
2023-08-12 |
Not clear |
| H Inouye, F S Domingues, A M Damas, M J Saraiva, E Lundgren, O Sandgren, D A Kirschne. Analysis of x-ray diffraction patterns from amyloid of biopsied vitreous humor and kidney of transthyretin (TTR) Met30 familial amyloidotic polyneuropathy (FAP) patients: axially arrayed TTR monomers constitute the protofilament. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 5. issue 3. 1999-01-15. PMID:9818053. |
familial amyloidotic polyneuropathy (fap) is characterized by deposits of amyloid fibers in which the major protein component is transthyretin (ttr). |
1999-01-15 |
2023-08-12 |
Not clear |
| O B Suhr, Y Ando, P I Ohlsson, A Olofsson, K Andersson, E Lundgren, M Ando, G Holmgre. Investigation into thiol conjugation of transthyretin in hereditary transthyretin amyloidosis. European journal of clinical investigation. vol 28. issue 8. 1998-12-03. PMID:9767365. |
familial amyloidotic polyneuropathy type i is caused by a variant transthyretin (ttr met-30). |
1998-12-03 |
2023-08-12 |
Not clear |
| N Sakashita, Y Ando, S L Marklund, P Nilsson, K Tashima, T Yamashita, K Takahash. Familial amyloidotic polyneuropathy type I with extracellular superoxide dismutase mutation: a case report. Human pathology. vol 29. issue 10. 1998-11-05. PMID:9781661. |
we report an autopsy case of familial amyloidotic polyneuropathy (fap) type i with mutations in both transthyretin (ttr) and extracellular superoxide dismutase (ec-sod). |
1998-11-05 |
2023-08-12 |
Not clear |
| T Tokuda, T Kondo, N Hanaoka, Y Takei, F Kametani, Y Yamada, Y Tamura, M Yoshida, N Yamawaki, S Iked. A selective transthyretin-adsorption column for the treatment of patients with familial amyloid polyneuropathy. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 5. issue 2. 1998-10-22. PMID:9686305. |
a transthyretin (ttr)-adsorption column has been developed for the removal of variant ttr from the plasma of patients with familial amyloid polyneuropathy (fap). |
1998-10-22 |
2023-08-12 |
Not clear |
| M P Sebastião, M J Saraiva, A M Dama. The crystal structure of amyloidogenic Leu55 --> Pro transthyretin variant reveals a possible pathway for transthyretin polymerization into amyloid fibrils. The Journal of biological chemistry. vol 273. issue 38. 1998-10-15. PMID:9733771. |
the x-ray crystal structure of the amyloidogenic leu55 --> pro transthyretin (ttr) variant, implicated as the causative agent in early-onset familial amyloidotic polyneuropathy (jacobson, d. r., mcfarlin, d. e., kane, i., and buxbaum, j. n. (1992) hum. |
1998-10-15 |
2023-08-12 |
Not clear |
| A Rydh, O Suhr, S O Hietala, K R Ahlström, M B Pepys, P N Hawkin. Serum amyloid P component scintigraphy in familial amyloid polyneuropathy: regression of visceral amyloid following liver transplantation. European journal of nuclear medicine. vol 25. issue 7. 1998-09-11. PMID:9662592. |
familial amyloid polyneuropathy (fap) associated with transthyretin (ttr) mutations is the commonest type of hereditary amyloidosis. |
1998-09-11 |
2023-08-12 |
Not clear |
| A J Stangou, P N Hawkins, N D Heaton, M Rela, M Monaghan, P Nihoyannopoulos, J O'Grady, M B Pepys, R William. Progressive cardiac amyloidosis following liver transplantation for familial amyloid polyneuropathy: implications for amyloid fibrillogenesis. Transplantation. vol 66. issue 2. 1998-08-19. PMID:9701270. |
circulating transthyretin (ttr) is derived from the liver, and orthotopic liver transplantation (olt) is widely performed for variant ttr-associated familial amyloid polyneuropathy (fap). |
1998-08-19 |
2023-08-12 |
Not clear |
| L Lobato, I Beirão, S M Guimarães, D Droz, S Guimarães, J P Grünfeld, L H Noë. Familial amyloid polyneuropathy type I (Portuguese): distribution and characterization of renal amyloid deposits. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 31. issue 6. 1998-07-02. PMID:9631837. |
renal amyloidosis has been considered rare and late in the evolution of the transthyretin (ttr) familial amyloid polyneuropathy (fap) of the portuguese type (type i). |
1998-07-02 |
2023-08-12 |
Not clear |
| S Riedstra, J P Ferreira, P M Cost. Study of an anti-human transthyretin immunoadsorbent. Influence of coupling chemistry on binding capacity and ligand leakage. Journal of chromatography. B, Biomedical sciences and applications. vol 705. issue 2. 1998-05-13. PMID:9521557. |
a variant of transthyretin (ttr val30met) has been identified as the main protein precursor of the amyloid fibrils deposited in familial amyloidotic polyneuropathy (fap). |
1998-05-13 |
2023-08-12 |
Not clear |
| E A Pomfret, W D Lewis, R L Jenkins, P Bergethon, S W Dubrey, J Reisinger, R H Falk, M Skinne. Effect of orthotopic liver transplantation on the progression of familial amyloidotic polyneuropathy. Transplantation. vol 65. issue 7. 1998-05-08. PMID:9565095. |
familial amyloidotic polyneuropathy (fap) is an autosomal dominant inherited disease associated with a mutant form of the protein transthyretin (ttr). |
1998-05-08 |
2023-08-12 |
Not clear |
| Y Ando, O Suhr, T Yamashita, P I Ohlsson, G Holmgren, K Obayashi, H Terazaki, C Mambule, M Uchino, M And. Detection of different forms of variant transthyretin (Met30) in cerebrospinal fluid. Neuroscience letters. vol 238. issue 3. 1998-04-24. PMID:9464635. |
to detect the variant transthyretin (ttr; met30) in cerebrospinal fluid (csf) of familial amyloidotic polyneuropathy (fap) patients, we have applied a new method using a centrifugal concentrator device and electrospray ionization mass spectrometry (esi-ms). |
1998-04-24 |
2023-08-12 |
Not clear |