| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroki Sano, Kazuhiko Namekata, Atsuko Kimura, Hiroshi Shitara, Xiaoli Guo, Chikako Harada, Yoshinori Mitamura, Takayuki Harad. Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma. Cell death & disease. vol 10. issue 2. 2020-04-21. PMID:30692515. |
suppressing oxidative stress in the retina may be an effective therapeutic strategy for glaucoma, a chronic neurodegenerative disease of the retinal ganglion cells (rgcs) and optic nerves. |
2020-04-21 |
2023-08-13 |
mouse |
| Frédéric Blond, Thierry Léveillar. Functional Genomics of the Retina to Elucidate its Construction and Deconstruction. International journal of molecular sciences. vol 20. issue 19. 2020-02-10. PMID:31590277. |
the retina has a central position both in fundamental biology and in the physiopathology of neurodegenerative diseases. |
2020-02-10 |
2023-08-13 |
Not clear |
| Alonso Sánchez-Cruz, Ana Martínez, Enrique J de la Rosa, Catalina Hernández-Sánche. GSK-3 Inhibitors: From the Brain to the Retina and Back Again. Advances in experimental medicine and biology. vol 1185. 2020-02-05. PMID:31884651. |
given the many molecular, cellular, and functional features shared by the brain and the retina in both physiological and pathological processes, drugs originally designed to treat neurodegenerative diseases of the brain could be useful candidates for the treatment of retinal degenerative pathologies. |
2020-02-05 |
2023-08-13 |
Not clear |
| José Martín-Nieto, Mary Luz Uribe, Julián Esteve-Rudd, María Trinidad Herrero, Laura Campell. A role for DJ-1 against oxidative stress in the mammalian retina. Neuroscience letters. vol 708. 2020-02-03. PMID:31276729. |
its function in counteracting oxidative stress in the retina, as it occurs in parkinson and other human neurodegenerative diseases, is, however, poorly understood. |
2020-02-03 |
2023-08-13 |
human |
| Isabel Martínez-Solís, Nuria Acero, Francisco Bosch-Morell, Encarna Castillo, María Eugenia González-Rosende, Dolores Muñoz-Mingarro, Teresa Ortega, María Amparo Sanahuja, Victoria Villagras. Neuroprotective Potential of Ginkgo biloba in Retinal Diseases. Planta medica. vol 85. issue 17. 2020-01-28. PMID:31266069. |
like other tissues of the central nervous system, the retina is susceptible to damage by oxidative processes that result in several neurodegenerative disease such as age-related macular degeneration, diabetic retinopathy, glaucoma, ischaemic retinal disease, retinal disease produced by light oxidation, and detached retina, among other diseases. |
2020-01-28 |
2023-08-13 |
Not clear |
| Alvita Vilkeviciute, Loresa Kriauciuniene, Romanas Chaleckis, Vytenis Pranas Deltuva, Rasa Liutkevicien. Disease markers. vol 2019. 2019-12-17. PMID:31191752. |
age-related macular degeneration (amd) is a progressive neurodegenerative disease of a central part of the neural retina (macula) and a leading cause of blindness in elderly people. |
2019-12-17 |
2023-08-13 |
Not clear |
| Nitin Chitranshi, Yogita Dheer, Sanjay Kumar, Stuart L Graham, Vivek Gupt. Molecular docking, dynamics, and pharmacology studies on bexarotene as an agonist of ligand-activated transcription factors, retinoid X receptors. Journal of cellular biochemistry. 2019-11-20. PMID:30746761. |
the protective effects of rxrs and rxr agonists have been reported in several neurodegenerative diseases, including in the retina. |
2019-11-20 |
2023-08-13 |
Not clear |
| Eleftherios I Paschalis, Fengyang Lei, Chengxin Zhou, Xiaohong Nancy Chen, Vassiliki Kapoulea, Pui-Chuen Hui, Reza Dana, James Chodosh, Demetrios G Vavvas, Claes H Dohlma. Microglia Regulate Neuroglia Remodeling in Various Ocular and Retinal Injuries. Journal of immunology (Baltimore, Md. : 1950). vol 202. issue 2. 2019-10-28. PMID:30541880. |
reactive microglia and infiltrating peripheral monocytes have been implicated in many neurodegenerative diseases of the retina and cns. |
2019-10-28 |
2023-08-13 |
mouse |
| Michael R R Böhm, Solon Thano. [The Aging Retina in the Context of Cerebral Neurodegenerative Diseases]. Klinische Monatsblatter fur Augenheilkunde. vol 236. issue 5. 2019-10-21. PMID:28599331. |
[the aging retina in the context of cerebral neurodegenerative diseases]. |
2019-10-21 |
2023-08-13 |
Not clear |
| Dominik M Fischer, François Paquet-Duran. [Development of cGMP Analogues for the Pharmacological Treatment of Neurodegenerative Diseases of the Retina]. Klinische Monatsblatter fur Augenheilkunde. vol 236. issue 3. 2019-10-21. PMID:30897644. |
[development of cgmp analogues for the pharmacological treatment of neurodegenerative diseases of the retina]. |
2019-10-21 |
2023-08-13 |
Not clear |
| Irene Bravo-Osuna, Vanessa Andrés-Guerrero, Alicia Arranz-Romera, Sergio Esteban-Pérez, Irene T Molina-Martínez, Rocío Herrero-Vanrel. Microspheres as intraocular therapeutic tools in chronic diseases of the optic nerve and retina. Advanced drug delivery reviews. vol 126. 2019-09-05. PMID:29339146. |
the purpose of the present review is to describe the use of microspheres in chronic neurodegenerative diseases affecting the retina and the optic nerve. |
2019-09-05 |
2023-08-13 |
Not clear |
| Jian Yang, Jing Yang, Yuyan Li, Yungen Xu, Chongzhao Ra. Near-infrared Fluorescence Ocular Imaging (NIRFOI) of Alzheimer's Disease. Molecular imaging and biology. vol 21. issue 1. 2019-07-29. PMID:29802553. |
therefore, the retina can be considered as an alternative organ for investigating neurodegenerative diseases, and an eye represents an ideal nirf imaging organ, due to its minimal opacity. |
2019-07-29 |
2023-08-13 |
Not clear |
| b' Jeffrey M Sundstrom, Cristina Hern\\xc3\\xa1ndez, Sarah R Weber, Yuanjun Zhao, Mitchell Dunklebarger, Natalia Tiberti, Tatiana Laremore, Olga Sim\\xc3\\xb3-Servat, Marta Garcia-Ramirez, Alistair J Barber, Thomas W Gardner, Rafael Sim\\xc3\\xb. Proteomic Analysis of Early Diabetic Retinopathy Reveals Mediators of Neurodegenerative Brain Diseases. Investigative ophthalmology & visual science. vol 59. issue 6. 2019-02-15. PMID:29847632.' |
our main goal was to examine whether, in the diabetic human retina, common proteins and pathways are shared with brain neurodegenerative diseases. |
2019-02-15 |
2023-08-13 |
human |
| Landon J Rohowetz, Jacob G Kraus, Peter Koule. Reactive Oxygen Species-Mediated Damage of Retinal Neurons: Drug Development Targets for Therapies of Chronic Neurodegeneration of the Retina. International journal of molecular sciences. vol 19. issue 11. 2019-01-23. PMID:30373222. |
the significance of oxidative stress in the development of chronic neurodegenerative diseases of the retina has become increasingly apparent in recent years. |
2019-01-23 |
2023-08-13 |
Not clear |
| Landon J Rohowetz, Jacob G Kraus, Peter Koule. Reactive Oxygen Species-Mediated Damage of Retinal Neurons: Drug Development Targets for Therapies of Chronic Neurodegeneration of the Retina. International journal of molecular sciences. vol 19. issue 11. 2019-01-23. PMID:30373222. |
recent studies have investigated the role of excess ros in the pathogenesis and development of chronic neurodegenerative diseases of the retina including glaucoma, diabetic retinopathy, and age-related macular degeneration. |
2019-01-23 |
2023-08-13 |
Not clear |
| Landon J Rohowetz, Jacob G Kraus, Peter Koule. Reactive Oxygen Species-Mediated Damage of Retinal Neurons: Drug Development Targets for Therapies of Chronic Neurodegeneration of the Retina. International journal of molecular sciences. vol 19. issue 11. 2019-01-23. PMID:30373222. |
here, we briefly outline recent developments that have contributed to our understanding of the role of ros in the pathogenesis of chronic neurodegenerative diseases of the retina. |
2019-01-23 |
2023-08-13 |
Not clear |
| Luciana M Pujol-Lereis, Gerhard Liebisch, Tina Schick, Yuchen Lin, Felix Grassmann, Koji Uchida, Peter F Zipfel, Sascha Fauser, Christine Skerka, Bernhard H F Webe. Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration. PloS one. vol 13. issue 8. 2019-01-22. PMID:30071029. |
sphingolipids are bioactive molecules associated with oxidative stress, inflammation, and neurodegenerative diseases, but poorly studied in the context of age-related macular degeneration (amd), a prevalent sight-threatening disease of the ageing retina. |
2019-01-22 |
2023-08-13 |
Not clear |
| D V Telegina, O S Kozhevnikova, N G Kolosov. Changes in Retinal Glial Cells with Age and during Development of Age-Related Macular Degeneration. Biochemistry. Biokhimiia. vol 83. issue 9. 2018-12-11. PMID:30472939. |
age is the major risk factor in the age-related macular degeneration (amd) which is a complex multifactor neurodegenerative disease of the retina and the main cause of irreversible vision loss in people over 60 years old. |
2018-12-11 |
2023-08-13 |
Not clear |
| M V Zueva, I V Tsapenko, O M Manko, A E Smoleevsk. [Alterations of physiological rhythms in neurodegenerative disorders: problems and prospects of light therapy]. Klinicheskaia meditsina. vol 94. issue 6. 2018-11-01. PMID:30289659. |
it is expected that the use of stimuli with fractal structure can help to restore the retina and brain’s functions in neurodegenerative diseases by reactivation of neuronal plasticity and be an innovative method for the treatment of neurodegenerative disorders. |
2018-11-01 |
2023-08-13 |
human |
| Sarah L Roche, Ana M Ruiz-Lopez, Jennifer N Moloney, Ashleigh M Byrne, Thomas G Cotte. Microglial-induced Müller cell gliosis is attenuated by progesterone in a mouse model of retinitis pigmentosa. Glia. vol 66. issue 2. 2018-07-18. PMID:29034506. |
gliosis is a feature of many neurodegenerative diseases of the retina, including retinitis pigmentosa. |
2018-07-18 |
2023-08-13 |
mouse |