| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stela Vujosevic, M Margarita Parra, M Elizabeth Hartnett, Louise O'Toole, Alessia Nuzzi, Celeste Limoli, Edoardo Villani, Paolo Nucc. Optical coherence tomography as retinal imaging biomarker of neuroinflammation/neurodegeneration in systemic disorders in adults and children. Eye (London, England). 2022-04-16. PMID:35428871. |
oct can non-invasively document changes in single retina layer thickness and structure due to neuronal and retinal glial cells (rgc) modifications in systemic and local inflammatory and neurodegenerative diseases. |
2022-04-16 |
2023-08-13 |
human |
| T J Hollingsworth, Xiangdi Wang, William A White, Raven N Simpson, Monica M Jablonsk. Chronic Proinflammatory Signaling Accelerates the Rate of Degeneration in a Spontaneous Polygenic Model of Inherited Retinal Dystrophy. Frontiers in pharmacology. vol 13. 2022-04-07. PMID:35387333. |
collectively, retinal neurodegenerative diseases are comprised of numerous subtypes of disorders which result in loss of a varying cell types in the retina. |
2022-04-07 |
2023-08-13 |
mouse |
| Leonardo Provetti Cunha, Leopoldo Antônio Pires, Marcelo Maroco Cruzeiro, Ana Laura Maciel Almeida, Luiza Cunha Martins, Pedro Nascimento Martins, Nadia Shigaeff, Thiago Cardoso Val. Optical coherence tomography in neurodegenerative disorders. Arquivos de neuro-psiquiatria. vol 80. issue 2. 2022-03-30. PMID:35352756. |
in this scenario, imaging studies focusing on the structures of the retina have increasingly been used for evaluating neurodegenerative diseases. |
2022-03-30 |
2023-08-13 |
Not clear |
| Leonardo Provetti Cunha, Leopoldo Antônio Pires, Marcelo Maroco Cruzeiro, Ana Laura Maciel Almeida, Luiza Cunha Martins, Pedro Nascimento Martins, Nadia Shigaeff, Thiago Cardoso Val. Optical coherence tomography in neurodegenerative disorders. Arquivos de neuro-psiquiatria. vol 80. issue 2. 2022-03-30. PMID:35352756. |
the retina shares embryological, histological, biochemical, microvascular and neurotransmitter similarities with the cerebral cortex, thus making it a uniquely promising biomarker for neurodegenerative diseases. |
2022-03-30 |
2023-08-13 |
Not clear |
| Xin Shi, Panpan Li, Hanhan Liu, Verena Prokosc. Oxidative Stress, Vascular Endothelium, and the Pathology of Neurodegeneration in Retina. Antioxidants (Basel, Switzerland). vol 11. issue 3. 2022-03-25. PMID:35326193. |
stress and endothelium dysfunction are suspected to be interlinked and associated with neurodegenerative diseases in the retina as well. |
2022-03-25 |
2023-08-13 |
Not clear |
| Xin Shi, Panpan Li, Hanhan Liu, Verena Prokosc. Oxidative Stress, Vascular Endothelium, and the Pathology of Neurodegeneration in Retina. Antioxidants (Basel, Switzerland). vol 11. issue 3. 2022-03-25. PMID:35326193. |
in this narrative review, we explore the role of os-led ed in the retina by focusing on mechanistic links between os and ed, ed in the pathophysiology of different retinal neurodegenerative conditions, and how a better understanding of the role of endothelial function could lead to new therapeutic approaches for neurodegenerative diseases in the retina. |
2022-03-25 |
2023-08-13 |
Not clear |
| Lorena Fuentes-Broto, Lorena Perdices, Francisco Segura, Elvira Orduna-Hospital, Gema Insa-Sánchez, Ana I Sánchez-Cano, Nicolás Cuenca, Isabel Pinill. Effects of Daily Melatonin Supplementation on Visual Loss, Circadian Rhythms, and Hepatic Oxidative Damage in a Rodent Model of Retinitis Pigmentosa. Antioxidants (Basel, Switzerland). vol 10. issue 11. 2021-11-30. PMID:34829724. |
retinitis pigmentosa (rp) is a group of inherited neurodegenerative diseases characterized by a progressive loss of visual function that primarily affect photoreceptors, resulting in the complete disorganization and remodeling of the retina. |
2021-11-30 |
2023-08-13 |
rat |
| Rong Rong, Mengxiao Wang, Mengling You, Haibo Li, Xiaobo Xia, Dan J. Pathogenesis and prospects for therapeutic clinical application of noncoding RNAs in glaucoma: Systematic perspectives. Journal of cellular physiology. vol 236. issue 10. 2021-11-29. PMID:33634475. |
glaucoma is a neurodegenerative disease of the retina, and one of the leading causes of blindness worldwide. |
2021-11-29 |
2023-08-13 |
human |
| Nicoletta Marchesi, Foroogh Fahmideh, Federica Boschi, Alessia Pascale, Annalisa Barbier. Ocular Neurodegenerative Diseases: Interconnection between Retina and Cortical Areas. Cells. vol 10. issue 9. 2021-11-22. PMID:34572041. |
ocular neurodegenerative diseases: interconnection between retina and cortical areas. |
2021-11-22 |
2023-08-13 |
Not clear |
| Fan Xia, Yonju Ha, Shuizhen Shi, Yi Li, Shengguo Li, Jonathan Luisi, Rakez Kayed, Massoud Motamedi, Hua Liu, Wenbo Zhan. Early alterations of neurovascular unit in the retina in mouse models of tauopathy. Acta neuropathologica communications. vol 9. issue 1. 2021-11-10. PMID:33762004. |
the retina, as the only visually accessible tissue in the central nervous system, has attracted significant attention for evaluating it as a biomarker for neurodegenerative diseases. |
2021-11-10 |
2023-08-13 |
mouse |
| Ryan J Bevan, Tim R Hughes, Pete A Williams, Mark A Good, B Paul Morgan, James E Morga. Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease. Acta neuropathologica communications. vol 8. issue 1. 2021-11-09. PMID:33287900. |
retinal ganglion cells, the output neurons of the retina, are vulnerable to damage in neurodegenerative diseases and are a potential opportunity for non-invasive clinical diagnosis and monitoring of alzheimer's progression. |
2021-11-09 |
2023-08-13 |
mouse |
| Eirini Christinaki, Hana Kulenovic, Xavier Hadoux, Nicole Baldassini, Jan Van Eijgen, Lies De Groef, Ingeborg Stalmans, Peter van Wijngaarde. Retinal imaging biomarkers of neurodegenerative diseases. Clinical & experimental optometry. 2021-11-09. PMID:34751086. |
retinal imaging is emerging as a method to detect features of a number of neurodegenerative diseases, given the anatomical and functional similarities between the retina and the brain. |
2021-11-09 |
2023-08-13 |
Not clear |
| Zeinab Amini-Farsani, Samira Asgharzad. The impact of miR-183/182/96 gene regulation on the maturation, survival, and function of photoreceptor cells in the retina. The Journal of comparative neurology. vol 528. issue 9. 2021-11-01. PMID:31785157. |
identifying the genes that are regulated by the mirna-183 cluster provides researchers with important insights into the complex development and regeneration mechanism of the retina and may offer a new way for maintaining and regenerating photoreceptor cells in neurodegenerative diseases. |
2021-11-01 |
2023-08-13 |
human |
| Soyoung Choi, Li Guo, Maria Francesca Cordeir. Retinal and Brain Microglia in Multiple Sclerosis and Neurodegeneration. Cells. vol 10. issue 6. 2021-11-01. PMID:34203793. |
in this review, we describe characteristics of cns microglia, including those in the retina, with a focus on their morphology, activation states and function in health, ageing, ms and other neurodegenerative diseases such as alzheimer's disease, parkinson's disease, glaucoma and retinitis pigmentosa, to highlight their activity in disease. |
2021-11-01 |
2023-08-13 |
Not clear |
| Jie Yan, Yiyi Chen, Yu Zhu, François Paquet-Duran. Programmed Non-Apoptotic Cell Death in Hereditary Retinal Degeneration: Crosstalk between cGMP-Dependent Pathways and PARthanatos? International journal of molecular sciences. vol 22. issue 19. 2021-11-01. PMID:34638907. |
misregulation of pcd mechanisms may be the underlying cause of neurodegenerative diseases of the retina, including hereditary retinal degeneration (rd). |
2021-11-01 |
2023-08-13 |
Not clear |
| Anna Sirés, Mireia Turch-Anguera, Patricia Bogdanov, Joel Sampedro, Hugo Ramos, Agustín Ruíz Lasa, Jianxin Huo, Shengli Xu, Kong-Peng Lam, Joaquín López-Soriano, M Jose Pérez-García, Cristina Hernández, Rafael Simó, Montse Solé, Joan X Comell. Faim knockout leads to gliosis and late-onset neurodegeneration of photoreceptors in the mouse retina. Journal of neuroscience research. 2021-10-29. PMID:34713467. |
the retina is a highly specialized tissue, and its degeneration has proved to precede pathological mechanisms of neurodegenerative diseases. |
2021-10-29 |
2023-08-13 |
mouse |
| Jennifer Ngolab, Michael Donohue, Alison Belsha, Jennifer Salazar, Paula Cohen, Sandhya Jaiswal, Veasna Tan, Devon Gessert, Shaina Korouri, Neelum T Aggarwal, Jessica Alber, Ken Johnson, Gregory Jicha, Christopher van Dyck, James Lah, Stephen Salloway, Reisa A Sperling, Paul S Aisen, Michael S Rafii, Robert A Rissma. Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial. Alzheimer's & dementia (Amsterdam, Netherlands). vol 13. issue 1. 2021-10-22. PMID:34430703. |
the retina and brain exhibit similar pathologies in patients diagnosed with neurodegenerative diseases. |
2021-10-22 |
2023-08-13 |
Not clear |
| Dongchang Xiao, Kangxin Jin, Suo Qiu, Qiannan Lei, Wanjing Huang, Haiqiao Chen, Jing Su, Qiang Xu, Zihui Xu, Bin Gou, Xiaoxiu Tie, Feng Liu, Sheng Liu, Yizhi Liu, Mengqing Xian. Frontiers in cell and developmental biology. vol 9. 2021-10-22. PMID:34671605. |
previous research into cell replacement therapy of these neurodegenerative diseases has been stalled due to the incapability for grafted rgcs to integrate into the retina and project properly along the long visual pathway. |
2021-10-22 |
2023-08-13 |
Not clear |
| Ashley A Rowe, Pinkal D Patel, Ruth Gordillo, Katherine J Wer. Replenishment of TCA cycle intermediates provides photoreceptor resilience against neurodegeneration during progression of retinitis pigmentosa. JCI insight. vol 6. issue 17. 2021-10-09. PMID:34292885. |
overall, targeting tca cycle activity in the neural retina promoted photoreceptor survival and visual function during neurodegenerative disease. |
2021-10-09 |
2023-08-13 |
Not clear |
| Assraa Hassan Jassim, McKay Cavanaugh, Jessica Stukel Shah, Rebecca Willits, Denise M Inma. Transcorneal Electrical Stimulation Reduces Neurodegenerative Process in a Mouse Model of Glaucoma. Annals of biomedical engineering. vol 49. issue 2. 2021-10-05. PMID:32974756. |
glaucoma is a neurodegenerative disease in which the retinal ganglion cell axons of the optic nerve degenerate concomitant with synaptic changes in the retina, leading finally to death of the retinal ganglion cells (rgcs). |
2021-10-05 |
2023-08-13 |
mouse |