Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ivana Basta, Ana Nikolic, Mario Losen, Pilar Martínez-Martínez, Vidosava Stojanovic, Slobodan Lavrnic, Marc de Baets, Dragana Lavrni. MuSK myasthenia gravis and Lambert-Eaton myasthenic syndrome in the same patient. Clinical neurology and neurosurgery. vol 114. issue 6. 2012-10-16. PMID:22421253. |
musk myasthenia gravis and lambert-eaton myasthenic syndrome in the same patient. |
2012-10-16 |
2023-08-12 |
Not clear |
Masakatsu Motomur. [The pathophysiology and treatment of autoimmune neuromuscular junction diseases]. Rinsho shinkeigaku = Clinical neurology. vol 51. issue 11. 2012-09-18. PMID:22277398. |
myasthenia gravis (mg) is caused by the failure of neuromuscular transmission mediated by autoantibodies against acetylcholine receptors (achr) and muscle-specific receptor tyrosine kinase (musk)/ldl-receptor related protein 4 which are achr-associated transmembrane post-synaptic proteins involved in achr aggregation. |
2012-09-18 |
2023-08-12 |
Not clear |
Kourosh Rezania, Betty Soliven, Joseph Baron, Helen Lin, Vikram Penumalli, Koen van Besie. Myasthenia gravis, an autoimmune manifestation of lymphoma and lymphoproliferative disorders: case reports and review of literature. Leukemia & lymphoma. vol 53. issue 3. 2012-08-03. PMID:21864038. |
myasthenia gravis (mg) is an autoimmune disease mediated by antibodies to acetylcholine receptors (achrs) or muscle specific tyrosine kinase (musk). |
2012-08-03 |
2023-08-12 |
Not clear |
Alexandra Pevzner, Benedikt Schoser, Katja Peters, Nicoleta-Carmen Cosma, Andromachi Karakatsani, Berthold Schalke, Arthur Melms, Stephan Kröge. Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis. Journal of neurology. vol 259. issue 3. 2012-07-03. PMID:21814823. |
autoantibodies against the tyrosine kinase muscle-specific kinase (musk) are responsible for 5-10% of all myasthenia gravis cases. |
2012-07-03 |
2023-08-12 |
mouse |
Alexandra Pevzner, Benedikt Schoser, Katja Peters, Nicoleta-Carmen Cosma, Andromachi Karakatsani, Berthold Schalke, Arthur Melms, Stephan Kröge. Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis. Journal of neurology. vol 259. issue 3. 2012-07-03. PMID:21814823. |
to this end we analyzed 13 sera from patients with generalized myasthenia gravis but without antibodies against achr or musk. |
2012-07-03 |
2023-08-12 |
mouse |
Shuuichi Mori, Masahiko Kishi, Sachiho Kubo, Takuyu Akiyoshi, Shigeru Yamada, Tsuyoshi Miyazaki, Tetsuro Konishi, Naoki Maruyama, Kazuhiro Shigemot. 3,4-Diaminopyridine improves neuromuscular transmission in a MuSK antibody-induced mouse model of myasthenia gravis. Journal of neuroimmunology. vol 245. issue 1-2. 2012-06-05. PMID:22409941. |
3,4-diaminopyridine improves neuromuscular transmission in a musk antibody-induced mouse model of myasthenia gravis. |
2012-06-05 |
2023-08-12 |
mouse |
Shuuichi Mori, Masahiko Kishi, Sachiho Kubo, Takuyu Akiyoshi, Shigeru Yamada, Tsuyoshi Miyazaki, Tetsuro Konishi, Naoki Maruyama, Kazuhiro Shigemot. 3,4-Diaminopyridine improves neuromuscular transmission in a MuSK antibody-induced mouse model of myasthenia gravis. Journal of neuroimmunology. vol 245. issue 1-2. 2012-06-05. PMID:22409941. |
this study investigated the effect of 3,4-diaminopyridine (3,4-dap), a potent potentiator of transmitter release, on neuromuscular transmission in vivo in a mouse model of myasthenia gravis (mg) caused by antibodies against muscle-specific kinase (musk; musk-mg) and ex vivo in diaphragm muscle from these mice. |
2012-06-05 |
2023-08-12 |
mouse |
David P Richman, Kayoko Nishi, Stuart W Morell, Jolene Mi Chang, Michael J Ferns, Robert L Wollmann, Ricardo A Maselli, Joachim Schnier, Mark A Agiu. Acute severe animal model of anti-muscle-specific kinase myasthenia: combined postsynaptic and presynaptic changes. Archives of neurology. vol 69. issue 4. 2012-05-31. PMID:22158720. |
to determine the pathogenesis of anti-muscle-specific kinase (musk) myasthenia, a newly described severe form of myasthenia gravis associated with musk antibodies characterized by focal muscle weakness and wasting and absence of acetylcholine receptor antibodies, and to determine whether antibodies to musk, a crucial protein in the formation of the neuromuscular junction (nmj) during development, can induce disease in the mature nmj. |
2012-05-31 |
2023-08-12 |
Not clear |
K Ramcharan, M Bahall, C Bodoe, S Khan, P Ewe, S Sharm. MuSK antibody positive myasthenia gravis in a 38-year old West Indian female. The West Indian medical journal. vol 60. issue 6. 2012-05-10. PMID:22512235. |
musk antibody positive myasthenia gravis in a 38-year old west indian female. |
2012-05-10 |
2023-08-12 |
Not clear |
Shuuichi Mori, Shigeru Yamada, Sachiho Kubo, Jie Chen, Seiji Matsuda, Masachika Shudou, Naoki Maruyama, Kazuhiro Shigemot. Divalent and monovalent autoantibodies cause dysfunction of MuSK by distinct mechanisms in a rabbit model of myasthenia gravis. Journal of neuroimmunology. vol 244. issue 1-2. 2012-05-08. PMID:22222307. |
divalent and monovalent autoantibodies cause dysfunction of musk by distinct mechanisms in a rabbit model of myasthenia gravis. |
2012-05-08 |
2023-08-12 |
rabbit |
Shuuichi Mori, Shigeru Yamada, Sachiho Kubo, Jie Chen, Seiji Matsuda, Masachika Shudou, Naoki Maruyama, Kazuhiro Shigemot. Divalent and monovalent autoantibodies cause dysfunction of MuSK by distinct mechanisms in a rabbit model of myasthenia gravis. Journal of neuroimmunology. vol 244. issue 1-2. 2012-05-08. PMID:22222307. |
although autoantibodies against musk have been demonstrated to cause myasthenia gravis (mg), the underlying pathogenic mechanism remains unclear because a major subclass of these antibodies is functionally monovalent. |
2012-05-08 |
2023-08-12 |
rabbit |
Stuart Viegas, Leslie Jacobson, Patrick Waters, Judith Cossins, Saiju Jacob, M Isabel Leite, Richard Webster, Angela Vincen. Passive and active immunization models of MuSK-Ab positive myasthenia: electrophysiological evidence for pre and postsynaptic defects. Experimental neurology. vol 234. issue 2. 2012-05-04. PMID:22326541. |
antibodies directed against the post-synaptic neuromuscular junction protein, muscle specific kinase (musk) are found in a small proportion of generalized myasthenia gravis (musk-mg) patients. |
2012-05-04 |
2023-08-12 |
mouse |
Earnest L Murray, Sachin Kedar, V V Vedanarayana. Transmission of maternal muscle-specific tyrosine kinase (MuSK) to offspring: report of two cases. Journal of clinical neuromuscular disease. vol 12. issue 2. 2012-03-26. PMID:21386774. |
familial occurrence of myasthenia gravis is uncommon and reports of maternal transmission of muscle-specific tyrosine kinase (musk) antibody myasthenia are rarer still. |
2012-03-26 |
2023-08-12 |
Not clear |
Earnest L Murray, Sachin Kedar, V V Vedanarayana. Transmission of maternal muscle-specific tyrosine kinase (MuSK) to offspring: report of two cases. Journal of clinical neuromuscular disease. vol 12. issue 2. 2012-03-26. PMID:21386774. |
we report two families with maternal transmission of musk antibody myasthenia gravis to the offspring by different mechanisms. |
2012-03-26 |
2023-08-12 |
Not clear |
Earnest L Murray, Sachin Kedar, V V Vedanarayana. Transmission of maternal muscle-specific tyrosine kinase (MuSK) to offspring: report of two cases. Journal of clinical neuromuscular disease. vol 12. issue 2. 2012-03-26. PMID:21386774. |
the first family demonstrates transmission genetic susceptibility of inheriting myasthenia gravis from musk antibodies, whereas the second one demonstrates transplacental transmission of musk antibodies at birth. |
2012-03-26 |
2023-08-12 |
Not clear |
Nikolaos Trakas, Paraskevi Zisimopoulou, Socrates J Tzarto. Development of a highly sensitive diagnostic assay for muscle-specific tyrosine kinase (MuSK) autoantibodies in myasthenia gravis. Journal of neuroimmunology. vol 240-241. 2012-01-30. PMID:21993075. |
development of a highly sensitive diagnostic assay for muscle-specific tyrosine kinase (musk) autoantibodies in myasthenia gravis. |
2012-01-30 |
2023-08-12 |
Not clear |
Nikolaos Trakas, Paraskevi Zisimopoulou, Socrates J Tzarto. Development of a highly sensitive diagnostic assay for muscle-specific tyrosine kinase (MuSK) autoantibodies in myasthenia gravis. Journal of neuroimmunology. vol 240-241. 2012-01-30. PMID:21993075. |
autoimmune myasthenia gravis is usually characterized by the presence of autoantibodies against the acetylcholine receptor (~80-90% of patients) or muscle-specific tyrosine kinase (musk) (~5% of patients). |
2012-01-30 |
2023-08-12 |
Not clear |
Y Kawakami, M Ito, M Hirayama, K Sahashi, B Ohkawara, A Masuda, H Nishida, N Mabuchi, A G Engel, K Ohn. Anti-MuSK autoantibodies block binding of collagen Q to MuSK. Neurology. vol 77. issue 20. 2012-01-05. PMID:22013178. |
muscle-specific receptor tyrosine kinase (musk) antibody-positive myasthenia gravis (mg) accounts for 5%-15% of autoimmune mg. musk mediates the agrin-signaling pathway and also anchors the collagenic tail subunit (colq) of acetylcholinesterase (ache). |
2012-01-05 |
2023-08-12 |
Not clear |
Amelia Evoli, Jon Lindstro. Myasthenia gravis with antibodies to MuSK: another step toward solving mystery? Neurology. vol 77. issue 20. 2012-01-05. PMID:22013184. |
myasthenia gravis with antibodies to musk: another step toward solving mystery? |
2012-01-05 |
2023-08-12 |
Not clear |
Davide Corda, Giovanni A Deiana, Marina Mulargia, Maria I Pirastru, Maria Serra, Maria G Piluzza, Carlo Carcassi, Gianpietro Sech. Familial autoimmune MuSK positive myasthenia gravis. Journal of neurology. vol 258. issue 8. 2011-12-12. PMID:21369718. |
familial autoimmune musk positive myasthenia gravis. |
2011-12-12 |
2023-08-12 |
Not clear |