| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nils Erik Gilhus, Jan J Verschuure. Myasthenia gravis: subgroup classification and therapeutic strategies. The Lancet. Neurology. vol 14. issue 10. 2015-12-22. PMID:26376969. |
subgroups based on serum antibodies and clinical features include early-onset, late-onset, thymoma, musk, lrp4, antibody-negative, and ocular forms of myasthenia gravis. |
2015-12-22 |
2023-08-13 |
Not clear |
| A I Tsonis, P Zisimopoulou, K Lazaridis, J Tzartos, E Matsigkou, V Zouvelou, R Mantegazza, C Antozzi, F Andreetta, A Evoli, F Deymeer, G Saruhan-Direskeneli, H Durmus, T Brenner, A Vaknin, S Berrih-Aknin, A Behin, T Sharshar, M De Baets, M Losen, P Martinez-Martinez, K A Kleopa, E Zamba-Papanicolaou, T Kyriakides, A Kostera-Pruszczyk, P Szczudlik, B Szyluk, D Lavrnic, I Basta, S Peric, C Tallaksen, A Maniaol, C Casasnovas Pons, J Pitha, M Jakubíkova, F Hanisch, S J Tzarto. MuSK autoantibodies in myasthenia gravis detected by cell based assay--A multinational study. Journal of neuroimmunology. vol 284. 2015-08-19. PMID:26025053. |
musk autoantibodies in myasthenia gravis detected by cell based assay--a multinational study. |
2015-08-19 |
2023-08-13 |
Not clear |
| W D Phillips, P Christadoss, M Losen, A R Punga, K Shigemoto, J Verschuuren, A Vincen. Guidelines for pre-clinical animal and cellular models of MuSK-myasthenia gravis. Experimental neurology. vol 270. 2015-08-18. PMID:25542979. |
muscle-specific tyrosine kinase (musk) autoantibodies are the hallmark of a form of myasthenia gravis (mg) that can challenge the neurologist and the experimentalist. |
2015-08-18 |
2023-08-13 |
mouse |
| Ana Nikolic, Ivana Basta, Vidosava Rakocevic Stojanovic, Zorica Stevic, Dragana Lavrni. Electrophysiological profile of the patients with MuSK positive myasthenia gravis. Neurological research. vol 36. issue 11. 2015-05-27. PMID:24825477. |
electrophysiological profile of the patients with musk positive myasthenia gravis. |
2015-05-27 |
2023-08-13 |
Not clear |
| Ana Nikolic, Ivana Basta, Vidosava Rakocevic Stojanovic, Zorica Stevic, Dragana Lavrni. Electrophysiological profile of the patients with MuSK positive myasthenia gravis. Neurological research. vol 36. issue 11. 2015-05-27. PMID:24825477. |
to determine the electrophysiological profile of our cohort of patients with muscle-specific tyrosine kinase (musk) positive myasthenia gravis (mg). |
2015-05-27 |
2023-08-13 |
Not clear |
| Stephen W Reddel, Marco Morsch, William D Phillip. Clinical and scientific aspects of muscle-specific tyrosine kinase-related myasthenia gravis. Current opinion in neurology. vol 27. issue 5. 2015-05-12. PMID:25159928. |
antibodies to muscle-specific tyrosine kinase (musk) characterize up to 5% of myasthenia gravis patients. |
2015-05-12 |
2023-08-13 |
Not clear |
| P Zisimopoulou, P Evangelakou, J Tzartos, K Lazaridis, V Zouvelou, R Mantegazza, C Antozzi, F Andreetta, A Evoli, F Deymeer, G Saruhan-Direskeneli, H Durmus, T Brenner, A Vaknin, S Berrih-Aknin, M Frenkian Cuvelier, T Stojkovic, M DeBaets, M Losen, P Martinez-Martinez, K A Kleopa, E Zamba-Papanicolaou, T Kyriakides, A Kostera-Pruszczyk, P Szczudlik, B Szyluk, D Lavrnic, I Basta, S Peric, C Tallaksen, A Maniaol, S J Tzarto. A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis. Journal of autoimmunity. vol 52. 2015-04-16. PMID:24373505. |
double-seronegative myasthenia gravis (dsn-mg, without detectable achr and musk antibodies) presents a serious gap in mg diagnosis and understanding. |
2015-04-16 |
2023-08-12 |
human |
| J S Yi, A Guidon, S Sparks, R Osborne, V C Juel, J M Massey, D B Sanders, K J Weinhold, J T Guptil. Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis. Journal of autoimmunity. vol 52. 2015-04-16. PMID:24378287. |
characterization of cd4 and cd8 t cell responses in musk myasthenia gravis. |
2015-04-16 |
2023-08-12 |
Not clear |
| J S Yi, A Guidon, S Sparks, R Osborne, V C Juel, J M Massey, D B Sanders, K J Weinhold, J T Guptil. Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis. Journal of autoimmunity. vol 52. 2015-04-16. PMID:24378287. |
muscle specific tyrosine kinase myasthenia gravis (musk mg) is a form of autoimmune mg that predominantly affects women and has unique clinical features, including prominent bulbar weakness, muscle atrophy, and excellent response to therapeutic plasma exchange. |
2015-04-16 |
2023-08-12 |
Not clear |
| Jeffrey T Guptill, John S Yi, Donald B Sanders, Amanda C Guidon, Vern C Juel, Janice M Massey, James F Howard, Flavia Scuderi, Emanuela Bartoccioni, Amelia Evoli, Kent J Weinhol. Characterization of B cells in muscle-specific kinase antibody myasthenia gravis. Neurology(R) neuroimmunology & neuroinflammation. vol 2. issue 2. 2015-03-06. PMID:25745635. |
to characterize b-cell subsets in patients with muscle-specific tyrosine kinase (musk) myasthenia gravis (mg). |
2015-03-06 |
2023-08-13 |
Not clear |
| Inga Koneczny, Judith Cossins, Patrick Waters, David Beeson, Angela Vincen. MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters. PloS one. vol 8. issue 11. 2015-02-23. PMID:24244707. |
musk myasthenia gravis igg4 disrupts the interaction of lrp4 with musk but both igg4 and igg1-3 can disperse preformed agrin-independent achr clusters. |
2015-02-23 |
2023-08-12 |
Not clear |
| Inga Koneczny, Judith Cossins, Patrick Waters, David Beeson, Angela Vincen. MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters. PloS one. vol 8. issue 11. 2015-02-23. PMID:24244707. |
a variable proportion of patients with generalized myasthenia gravis (mg) have autoantibodies to muscle specific tyrosine kinase (musk). |
2015-02-23 |
2023-08-12 |
Not clear |
| Nazanin Ghazanfari, Marco Morsch, Stephen W Reddel, Simon X Liang, William D Phillip. Muscle-specific kinase (MuSK) autoantibodies suppress the MuSK pathway and ACh receptor retention at the mouse neuromuscular junction. The Journal of physiology. vol 592. issue 13. 2015-02-21. PMID:24860174. |
muscle-specific kinase (musk) autoantibodies from myasthenia gravis patients can block the activation of musk in vitro and/or reduce the postsynaptic localization of musk. |
2015-02-21 |
2023-08-13 |
mouse |
| Arnab Barik, Yisheng Lu, Anupama Sathyamurthy, Andrew Bowman, Chengyong Shen, Lei Li, Wen-cheng Xiong, Lin Me. LRP4 is critical for neuromuscular junction maintenance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 42. 2015-02-06. PMID:25319686. |
mutations have been identified in agrin, musk, and lrp4 in patients with congenital myasthenic syndrome, and patients with myasthenia gravis develop antibodies against agrin, lrp4, and musk. |
2015-02-06 |
2023-08-13 |
mouse |
| Ozgur Duman, Resit Koken, R Taner Baran, Senay Haspolat, Haluk Topalogl. Infantile anti-MuSK positive myasthenia gravis in a patient with autoimmune polyendocrinopathy type 3. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 18. issue 4. 2015-02-02. PMID:24685514. |
myasthenia gravis (mg) is an autoimmune disorder caused by autoantibodies and related to the muscle nicotinic acetylcholine receptor (achr) or muscle-specific tyrosine kinase (musk). |
2015-02-02 |
2023-08-12 |
Not clear |
| Lamprini Skriapa, Paraskevi Zisimopoulou, Nikolaos Trakas, Eirini Grapsa, Socrates J Tzarto. Expression of extracellular domains of muscle specific kinase (MuSK) and use as immunoadsorbents for the development of an antigen-specific therapy. Journal of neuroimmunology. vol 276. issue 1-2. 2015-02-02. PMID:25262156. |
antibodies against musk seem to be the pathogenic factor in approximately 5-8% of myasthenia gravis (mg) patients. |
2015-02-02 |
2023-08-13 |
Not clear |
| Bin Zhang, Chengyong Shen, Beverly Bealmear, Samia Ragheb, Wen-Cheng Xiong, Richard A Lewis, Robert P Lisak, Lin Me. Autoantibodies to agrin in myasthenia gravis patients. PloS one. vol 9. issue 3. 2014-12-28. PMID:24632822. |
to determine if patients with myasthenia gravis (mg) have antibodies to agrin, a proteoglycan released by motor neurons and is critical for neuromuscular junction (nmj) formation, we collected serum samples from 93 patients with mg with known status of antibodies to acetylcholine receptor (achr), muscle specific kinase (musk) and lipoprotein-related 4 (lrp4) and samples from control subjects (healthy individuals and individuals with other diseases). |
2014-12-28 |
2023-08-12 |
human |
| Nazanin Ghazanfari, Marco Morsch, Nigel Tse, Stephen W Reddel, William D Phillip. Effects of the ß2-adrenoceptor agonist, albuterol, in a mouse model of anti-MuSK myasthenia gravis. PloS one. vol 9. issue 2. 2014-11-08. PMID:24505322. |
here, for the first time, we examined the potential benefit of albuterol in a mouse model of anti-muscle specific kinase (musk) myasthenia gravis. |
2014-11-08 |
2023-08-12 |
mouse |
| Rie Ohta, Masakatsu Motomur. [Autoantibodies detected in acetylcholine receptor antibody-negative myasthenia gravis]. Rinsho byori. The Japanese journal of clinical pathology. vol 62. issue 3. 2014-09-18. PMID:24800501. |
myasthenia gravis (mg) is caused by the failure of neuromuscular transmission mediated by pathogenic autoantibodies (abs) against the acetylcholine receptor (achr), muscle-specific receptor tyrosine kinase (musk), and unknown autoantibodies. |
2014-09-18 |
2023-08-13 |
Not clear |
| Sandra George, Silvia Paulick, Ilka Knütter, Nadja Röber, Rico Hiemann, Dirk Roggenbuck, Karsten Conrad, Jan-Heiner Küppe. Stable expression of human muscle-specific kinase in HEp-2 M4 cells for automatic immunofluorescence diagnostics of myasthenia gravis. PloS one. vol 9. issue 1. 2014-09-08. PMID:24416182. |
muscle-specific kinase (musk) belongs to the nicotinic acetylcholine receptor complex which is targeted by pathogenic autoantibodies causing myasthenia gravis. |
2014-09-08 |
2023-08-12 |
human |