Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
James B Caress, Christopher H Hunt, Sat Dev Batis. Anti-MuSK myasthenia gravis presenting with purely ocular findings. Archives of neurology. vol 62. issue 6. 2005-06-30. PMID:15956173. |
antibodies to a muscle-specific receptor tyrosine kinase (musk) have been found in approximately 40% of patients with generalized myasthenia gravis who are seronegative for the antiacetylcholine receptor antibody. |
2005-06-30 |
2023-08-12 |
Not clear |
Ian Matthews, Shu Chen, Rachel Hewer, Vivienne McGrath, Jadwiga Furmaniak, Bernard Rees Smit. Muscle-specific receptor tyrosine kinase autoantibodies--a new immunoprecipitation assay. Clinica chimica acta; international journal of clinical chemistry. vol 348. issue 1-2. 2005-06-16. PMID:15369741. |
it has been reported that measurement of autoantibodies to a muscle-specific receptor tyrosine kinase (musk) may be useful in the assessment and management of patients with acetylcholine receptor antibody (achrab)-negative myasthenia gravis (mg). |
2005-06-16 |
2023-08-12 |
Not clear |
Hirokazu Shiraishi, Masakatsu Motomura, Toshiro Yoshimura, Takayasu Fukudome, Taku Fukuda, Yoko Nakao, Mitsuhiro Tsujihata, Angela Vincent, Katsumi Eguch. Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis. Annals of neurology. vol 57. issue 2. 2005-03-23. PMID:15668981. |
acetylcholine receptors loss and postsynaptic damage in musk antibody-positive myasthenia gravis. |
2005-03-23 |
2023-08-12 |
Not clear |
Hirokazu Shiraishi, Masakatsu Motomura, Toshiro Yoshimura, Takayasu Fukudome, Taku Fukuda, Yoko Nakao, Mitsuhiro Tsujihata, Angela Vincent, Katsumi Eguch. Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis. Annals of neurology. vol 57. issue 2. 2005-03-23. PMID:15668981. |
muscle-specific tyrosine kinase (musk) antibodies are found in some patients with "seronegative" myasthenia gravis (mg), but how they cause myasthenic symptoms is not clear. |
2005-03-23 |
2023-08-12 |
Not clear |
Kazuhiro End. [Advances in neuroimmunological laboratory studies on neuromuscular diseases]. Rinsho byori. The Japanese journal of clinical pathology. vol 52. issue 9. 2005-02-01. PMID:15552936. |
an explanation for muscular weakness in 10-15% of patients with seronegative myasthenia gravis who lack autoantibodies to acetylcholine receptors(achrs) appears to be the autoantibodies to muscle-specific receptor tyrosine kinase (musk). |
2005-02-01 |
2023-08-12 |
Not clear |
Duygu Selcen, Taku Fukuda, Xin-Ming Shen, Andrew G Enge. Are MuSK antibodies the primary cause of myasthenic symptoms? Neurology. vol 62. issue 11. 2004-12-20. PMID:15184594. |
to investigate the morphologic, electrophysiologic, and molecular correlates of muscle-specific tyrosine kinase-seropositive [musk(+)] myasthenia gravis (mg). |
2004-12-20 |
2023-08-12 |
Not clear |
Jiann-Horng Yeh, Wei-Hung Chen, Hou-Chang Chiu, Angela Vincen. Low frequency of MuSK antibody in generalized seronegative myasthenia gravis among Chinese. Neurology. vol 62. issue 11. 2004-12-20. PMID:15184635. |
low frequency of musk antibody in generalized seronegative myasthenia gravis among chinese. |
2004-12-20 |
2023-08-12 |
Not clear |
Xian Chu Kong, Patrizia Barzaghi, Markus A Rueg. Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference. EMBO reports. vol 5. issue 2. 2004-11-19. PMID:14749715. |
moreover, they show that musk is also required for the maintenance of the nmj, offering a mechanistic explanation for the myasthenia gravis caused by auto-antibodies to musk. |
2004-11-19 |
2023-08-12 |
mouse |
P Ian Andrew. Autoimmune myasthenia gravis in childhood. Seminars in neurology. vol 24. issue 1. 2004-08-19. PMID:15229797. |
the recent identification of an autoimmune process targeting muscle-specific kinase (musk) in a subset of seronegative patients with autoimmune myasthenia gravis promises to improve diagnostic accuracy and redirect therapy in at least some seronegative children and adolescents with myasthenia. |
2004-08-19 |
2023-08-12 |
Not clear |
Lan Zhou, John McConville, Vinay Chaudhry, Robert N Adams, Richard L Skolasky, Angela Vincent, Daniel B Drachma. Clinical comparison of muscle-specific tyrosine kinase (MuSK) antibody-positive and -negative myasthenic patients. Muscle & nerve. vol 30. issue 1. 2004-08-03. PMID:15221879. |
we assayed cryopreserved sera from 38 acetylcholine receptor (achr) antibody-negative patients with myasthenia gravis (mg) who were followed clinically for muscle-specific tyrosine kinase (musk) antibodies and analyzed and compared their clinical characteristics. |
2004-08-03 |
2023-08-12 |
Not clear |
P Gajdo. [Seronegative myasthenia gravis]. Revue neurologique. vol 160. issue 2. 2004-05-11. PMID:15034472. |
antibodies directed against the muscle receptor of tyrosine kinase (anti musk antibodies) were recently demonstrated in 40 to 70 p.cent of patients with sero-negative myasthenia gravis. |
2004-05-11 |
2023-08-12 |
Not clear |
John McConville, Maria Elena Farrugia, David Beeson, Uday Kishore, Richard Metcalfe, John Newsom-Davis, Angela Vincen. Detection and characterization of MuSK antibodies in seronegative myasthenia gravis. Annals of neurology. vol 55. issue 4. 2004-05-07. PMID:15048899. |
detection and characterization of musk antibodies in seronegative myasthenia gravis. |
2004-05-07 |
2023-08-12 |
rat |
John McConville, Maria Elena Farrugia, David Beeson, Uday Kishore, Richard Metcalfe, John Newsom-Davis, Angela Vincen. Detection and characterization of MuSK antibodies in seronegative myasthenia gravis. Annals of neurology. vol 55. issue 4. 2004-05-07. PMID:15048899. |
antibodies to rat muscle specific kinase, musk, have recently been identified in some generalized "seronegative" myasthenia gravis (snmg) patients, who are often females with marked bulbar symptoms. |
2004-05-07 |
2023-08-12 |
rat |
Yohan Liyanage, Werner Hoch, David Beeson, Angela Vincen. The agrin/muscle-specific kinase pathway: new targets for autoimmune and genetic disorders at the neuromuscular junction. Muscle & nerve. vol 25. issue 1. 2002-01-29. PMID:11754179. |
here, we summarize briefly the genetic and autoimmune disorders that affect neuromuscular transmission, and the identified targets, including new evidence that antibodies to muscle-specific receptor tyrosine kinase (musk) are involved in the pathogenesis of acetylcholine receptor (achr) antibody-negative myasthenia gravis. |
2002-01-29 |
2023-08-12 |
Not clear |
W Hoch, J McConville, S Helms, J Newsom-Davis, A Melms, A Vincen. Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nature medicine. vol 7. issue 3. 2001-04-05. PMID:11231638. |
auto-antibodies to the receptor tyrosine kinase musk in patients with myasthenia gravis without acetylcholine receptor antibodies. |
2001-04-05 |
2023-08-12 |
Not clear |