| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neil G Simon, Stephen W Reddel, Matthew C Kiernan, Robert Layze. Muscle-specific kinase antibodies: a novel cause of peripheral nerve hyperexcitability? Muscle & nerve. vol 48. issue 5. 2014-01-07. PMID:23720161. |
antibodies that target the postsynaptic neuromuscular junction (nmj) protein, muscle-specific kinase (musk), have been associated with myasthenia gravis (mg), often with cramps and fasciculations, after administration of acetylcholinesterase inhibitors (ache-i). |
2014-01-07 |
2023-08-12 |
Not clear |
| Shuuichi Mori, Kazuhiro Shigemot. Mechanisms associated with the pathogenicity of antibodies against muscle-specific kinase in myasthenia gravis. Autoimmunity reviews. vol 12. issue 9. 2014-01-06. PMID:23537506. |
the presence of autoantibodies against muscle-specific kinase (musk) at the neuromuscular junction (nmj) results in myasthenia gravis (mg). |
2014-01-06 |
2023-08-12 |
Not clear |
| Steven J Burden, Norihiro Yumoto, Wei Zhan. The role of MuSK in synapse formation and neuromuscular disease. Cold Spring Harbor perspectives in biology. vol 5. issue 5. 2013-12-19. PMID:23637281. |
mutations in musk and in genes that function in the musk signaling pathway, including dok-7, cause congenital myasthenia, and autoantibodies to musk, lrp4, and acetylcholine receptors are responsible for myasthenia gravis. |
2013-12-19 |
2023-08-12 |
Not clear |
| Marco Morsch, Stephen W Reddel, Nazanin Ghazanfari, Klaus V Toyka, William D Phillip. Pyridostigmine but not 3,4-diaminopyridine exacerbates ACh receptor loss and myasthenia induced in mice by muscle-specific kinase autoantibody. The Journal of physiology. vol 591. issue 10. 2013-12-05. PMID:23440963. |
here we formally examined the effects of these compounds in the antibody-induced mouse model of anti-muscle-specific kinase (musk) myasthenia gravis. |
2013-12-05 |
2023-08-12 |
mouse |
| Michal Haran, Ami Schattner, Andras Mate, Danield Starobin, Gilad Haran, Mordechai Shtalri. Can a rare form of myasthenia gravis shed additional light on disease mechanisms? Clinical neurology and neurosurgery. vol 115. issue 5. 2013-10-17. PMID:22854280. |
the diagnosis of myasthenia gravis (mg) was finally confirmed by direct measurement of diaphragmatic strength using magnetic nerve stimulation providing clear cut evidence of significant fatigable weakness and the demonstration of muscle-specific kinase (musk) serum antibodies using a novel cell-based assay. |
2013-10-17 |
2023-08-12 |
Not clear |
| Sanjeev Rajakulendran, Stuart Viegas, Jennifer Spillane, Robin S Howar. Clinically biphasic myasthenia gravis with both AChR and MuSK antibodies. Journal of neurology. vol 259. issue 12. 2013-09-05. PMID:22955633. |
clinically biphasic myasthenia gravis with both achr and musk antibodies. |
2013-09-05 |
2023-08-12 |
Not clear |
| Akiko Nagaishi, Waka Sakai, Masakatsu Motomur. [Novel autoantibodies in myasthenia gravis]. Nihon rinsho. Japanese journal of clinical medicine. vol 71. issue 5. 2013-08-22. PMID:23777098. |
patients with myasthenia gravis(mg) are divided into three groups: (1) acetylcholine receptor antibody positive mg: 80%, (2) muscle-specific receptor tyrosine kinase (musk) antibody positive mg: 5-10%, and (3) double seronegative mg. |
2013-08-22 |
2023-08-12 |
Not clear |
| Kinji Ohno, Mikako Ito, Yu Kawakami, Eric Krejci, Andrew G Enge. Specific binding of collagen Q to the neuromuscular junction is exploited to cure congenital myasthenia and to explore bases of myasthenia gravis. Chemico-biological interactions. vol 203. issue 1. 2013-05-28. PMID:22981737. |
musk antibody-positive myasthenia gravis (mg) accounts for 5-15% of autoimmune mg. as achr deficiency is typically mild and as cholinesterase inhibitors are generally ineffective or worsen myasthenic symptoms, we asked if the patient's musk-igg interferes with binding of colq to musk. |
2013-05-28 |
2023-08-12 |
mouse |
| Toshiyuki Yamamoto, Norio Chihara, Madoka Mori-Yoshimura, Miho Murat. Videofluorographic detection of anti-muscle-specific kinase-positive myasthenia gravis. American journal of otolaryngology. vol 33. issue 6. 2013-05-07. PMID:22673097. |
furthermore, the anti-muscle-specific kinase (musk) antibody titer was elevated, and anti-musk antibody-positive myasthenia gravis (musk-mg) was diagnosed. |
2013-05-07 |
2023-08-12 |
Not clear |
| Ai Hosaka, Hiroshi Takuma, Kiyoe Ohta, Akira Tamaok. An ocular form of myasthenia gravis with a high titer of anti-MuSK antibodies during a long-term follow-up. Internal medicine (Tokyo, Japan). vol 51. issue 21. 2013-04-26. PMID:23124154. |
we herein report a case of ocular myasthenia gravis (mg) that was highly positive for anti-muscle-specific tyrosine kinase (musk) antibodies. |
2013-04-26 |
2023-08-12 |
Not clear |
| Angela Vincent, Patrick Waters, M Isabel Leite, Leslie Jacobson, Inga Koneczny, Judith Cossins, David Beeso. Antibodies identified by cell-based assays in myasthenia gravis and associated diseases. Annals of the New York Academy of Sciences. vol 1274. 2013-04-03. PMID:23252902. |
we have established cell-based assays for the improved detection of acetylcholine receptor (achr) and muscle-specific kinase (musk) antibodies in myasthenia gravis. |
2013-04-03 |
2023-08-12 |
Not clear |
| Fulvio Baggi, Francesca Andreetta, Lorenzo Maggi, Paolo Confalonieri, Lucia Morandi, Franco Salerno, Pia Bernasconi, Cristina Montomoli, Massimo Barberis, Renato Mantegazza, Carlo Antozz. Complete stable remission and autoantibody specificity in myasthenia gravis. Neurology. vol 80. issue 2. 2013-03-01. PMID:23255823. |
patients with myasthenia gravis (mg) are subgrouped as acetylcholine receptor (achr)-positive, muscle-specific kinase (musk)-positive, and achr/musk-negative mg (or double negative [dn]) on the basis of autoantibody assay. |
2013-03-01 |
2023-08-12 |
Not clear |
| Masaharu Takamori, Tatsufumi Nakamura, Masakatsu Motomur. Antibodies against Wnt receptor of muscle-specific tyrosine kinase in myasthenia gravis. Journal of neuroimmunology. vol 254. issue 1-2. 2013-02-25. PMID:22999188. |
muscle-specific tyrosine kinase (musk) antibodies are detected in a proportion of myasthenia gravis (mg) patients who are negative for acetylcholine receptor (achr) antibodies and have prominent bulbar weakness and crises. |
2013-02-25 |
2023-08-12 |
Not clear |
| Konstantinos Lazaridis, Paraskevi Zisimopoulou, George Lagoumintzis, Labrini Skriapa, Nikos Trakas, Panagiota Evangelakou, Ioannis Kanelopoulos, Eirini Grapsa, Kostas Poulas, Socrates Tzarto. Antigen-specific apheresis of autoantibodies in myasthenia gravis. Annals of the New York Academy of Sciences. vol 1275. 2013-02-21. PMID:23278571. |
myasthenia gravis (mg) is an autoimmune disorder affecting the neuromuscular junction, usually caused by autoantibodies against the acetylcholine receptor (achr) or the muscle-specific kinase (musk). |
2013-02-21 |
2023-08-12 |
Not clear |
| Jaap J Plomp, Maartje G Huijbers, Silvère M van der Maarel, Jan J Verschuure. Pathogenic IgG4 subclass autoantibodies in MuSK myasthenia gravis. Annals of the New York Academy of Sciences. vol 1275. 2013-02-21. PMID:23278586. |
pathogenic igg4 subclass autoantibodies in musk myasthenia gravis. |
2013-02-21 |
2023-08-12 |
mouse |
| Jaap J Plomp, Maartje G Huijbers, Silvère M van der Maarel, Jan J Verschuure. Pathogenic IgG4 subclass autoantibodies in MuSK myasthenia gravis. Annals of the New York Academy of Sciences. vol 1275. 2013-02-21. PMID:23278586. |
autoantibodies against muscle-specific kinase (musk), a protein essential for clustering of acetylcholine receptors at the neuromuscular junction (nmj), are detected in the serum of a proportion of myasthenia gravis (mg) patients. |
2013-02-21 |
2023-08-12 |
mouse |
| Judith Cossins, Katsiaryna Belaya, Katarzyna Zoltowska, Inga Koneczny, Susan Maxwell, Leslie Jacobson, Maria Isabel Leite, Patrick Waters, Angela Vincent, David Beeso. The search for new antigenic targets in myasthenia gravis. Annals of the New York Academy of Sciences. vol 1275. 2013-02-21. PMID:23278587. |
around 80% of myasthenia gravis patients have antibodies against the acetylcholine receptor, and 0-60% of the remaining patients have antibodies against the muscle-specific tyrosine kinase, musk. |
2013-02-21 |
2023-08-12 |
Not clear |
| Elisabeth Chroni, Anna Rostedt Pung. Neurophysiological characteristics of MuSK antibody positive myasthenia gravis mice: focal denervation and hypersensitivity to acetylcholinesterase inhibitors. Journal of the neurological sciences. vol 316. issue 1-2. 2013-01-22. PMID:22251934. |
neurophysiological characteristics of musk antibody positive myasthenia gravis mice: focal denervation and hypersensitivity to acetylcholinesterase inhibitors. |
2013-01-22 |
2023-08-12 |
mouse |
| Marco Morsch, Stephen W Reddel, Nazanin Ghazanfari, Klaus V Toyka, William D Phillip. Muscle specific kinase autoantibodies cause synaptic failure through progressive wastage of postsynaptic acetylcholine receptors. Experimental neurology. vol 237. issue 2. 2012-11-13. PMID:22789393. |
patient autoantibodies against muscle specific kinase (musk) deplete musk from the postsynaptic membrane and reproduce signs of myasthenia gravis when injected into mice. |
2012-11-13 |
2023-08-12 |
mouse |
| Konstantinos Poulas, Euphrosyni Koutsouraki, Gregory Kordas, Anna Kokla, Socrates J Tzarto. Anti-MuSK- and anti-AChR-positive myasthenia gravis induced by d-penicillamine. Journal of neuroimmunology. vol 250. issue 1-2. 2012-10-18. PMID:22683336. |
myasthenia gravis (mg) is an autoimmune disorder of the neuromuscular junction usually caused by antibodies to the nicotinic acetylcholine receptor (achr) and occasionally to muscle-specific kinase (musk). |
2012-10-18 |
2023-08-12 |
Not clear |