| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Barbara M Misof, Paul Roschger, Hugh J McMillan, Jinhui Ma, Klaus Klaushofer, Frank Rauch, Leanne M War. Histomorphometry and Bone Matrix Mineralization Before and After Bisphosphonate Treatment in Boys With Duchenne Muscular Dystrophy: A Paired Transiliac Biopsy Study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 31. issue 5. 2017-12-15. PMID:26615086. |
duchenne muscular dystrophy (dmd) is a genetic disorder causing progressive muscle weakness. |
2017-12-15 |
2023-08-13 |
Not clear |
| Elizabeth M van der Pijl, Maaike van Putten, Erik H Niks, Jan J G M Verschuuren, Annemieke Aartsma-Rus, Jaap J Plom. Characterization of neuromuscular synapse function abnormalities in multiple Duchenne muscular dystrophy mouse models. The European journal of neuroscience. vol 43. issue 12. 2017-11-16. PMID:27037492. |
it is possible that the absence of dystrophin at nmjs in dmd causes neuromuscular transmission defects that aggravate muscle weakness. |
2017-11-16 |
2023-08-13 |
mouse |
| Laura A Bertrand, Eric J Askeland, Katherine D Mathews, Bradley A Erickson, Christopher S Coope. Prevalence and bother of patient-reported lower urinary tract symptoms in the muscular dystrophies. Journal of pediatric urology. vol 12. issue 6. 2017-10-02. PMID:27567595. |
duchenne muscular dystrophy (dmd) and the less severe becker muscular dystrophy (bmd) are characterized by progressive muscle weakness and eventual loss of ambulation, and result from mutations in the dystrophin gene. |
2017-10-02 |
2023-08-13 |
Not clear |
| Nicholas P Whitehead, Kenneth L Bible, Min Jeong Kim, Guy L Odom, Marvin E Adams, Stanley C Froehne. Validation of ultrasonography for non-invasive assessment of diaphragm function in muscular dystrophy. The Journal of physiology. vol 594. issue 24. 2017-09-14. PMID:27570057. |
diaphragm amplitude correlated positively with ex vivo force values and negatively with diaphragm fibrosis, a major cause of dmd muscle weakness. |
2017-09-14 |
2023-08-13 |
mouse |
| Xin Xie, Sophia Y Tsai, Ming-Jer Tsa. COUP-TFII regulates satellite cell function and muscular dystrophy. The Journal of clinical investigation. vol 126. issue 10. 2017-09-11. PMID:27617862. |
furthermore, inhibition of coup-tfii preserved sc function and counteracted the muscle weakness associated with duchenne-like dystrophy in the murine model, suggesting that targeting coup-tfii is a potential treatment for dmd. |
2017-09-11 |
2023-08-13 |
mouse |
| Jennifer G Andrews, Aida Soim, Shree Pandya, Christina P Westfield, Emma Ciafaloni, Deborah J Fox, David J Birnkrant, Christopher M Cunniff, Daniel W Sheeha. Respiratory Care Received by Individuals With Duchenne Muscular Dystrophy From 2000 to 2011. Respiratory care. vol 61. issue 10. 2017-08-29. PMID:27507176. |
duchenne muscular dystrophy (dmd) causes progressive respiratory muscle weakness and decline in function, which can go undetected without monitoring. |
2017-08-29 |
2023-08-13 |
Not clear |
| Mayra Priscila Boscolo Alvarez, Talita Dias da Silva, Francis Meire Favero, Vitor Engrácia Valenti, Rodrigo Daminello Raimundo, Luiz Carlos Marques Vanderlei, David M Garner, Carlos Bandeira de Mello Monteir. Autonomic Modulation in Duchenne Muscular Dystrophy during a Computer Task: A Prospective Control Trial. PloS one. vol 12. issue 1. 2017-08-07. PMID:28118369. |
duchenne muscular dystrophy (dmd) is characterized by progressive muscle weakness that can lead to disability. |
2017-08-07 |
2023-08-13 |
human |
| Juliette Ropars, Mathieu Lempereur, Carole Vuillerot, Vincent Tiffreau, Sylviane Peudenier, Jean-Marie Cuisset, Yann Pereon, Fabien Leboeuf, Ludovic Delporte, Yannick Delpierre, Raphaël Gross, Sylvain Brochar. Muscle Activation during Gait in Children with Duchenne Muscular Dystrophy. PloS one. vol 11. issue 9. 2017-08-04. PMID:27622734. |
since the motor command is normal in dmd, the hyper-activity and co-contractions likely compensate for gait instability and muscle weakness, however may have negative consequences on the muscles and may increase the energy cost of gait. |
2017-08-04 |
2023-08-13 |
Not clear |
| Margaret E Benny Klimek, Arpana Sali, Sree Rayavarapu, Jack H Van der Meulen, Kanneboyina Nagaraj. Effect of the IL-1 Receptor Antagonist Kineret® on Disease Phenotype in mdx Mice. PloS one. vol 11. issue 5. 2017-07-10. PMID:27213537. |
the pathology of dmd manifests in patients with progressive muscle weakness, loss of ambulation and ultimately death. |
2017-07-10 |
2023-08-13 |
mouse |
| Elizabeth M Gibbs, Jamie L Marshall, Eva Ma, Thien M Nguyen, Grace Hong, Jessica S Lam, Melissa J Spencer, Rachelle H Crosbie-Watso. High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMD. Human molecular genetics. vol 25. issue 24. 2017-06-09. PMID:27798107. |
duchenne muscular dystrophy (dmd) is a genetic disorder that causes progressive muscle weakness, ultimately leading to early mortality in affected teenagers and young adults. |
2017-06-09 |
2023-08-13 |
mouse |
| J Huard, X Mu, A L. Evolving paradigms in clinical pharmacology and therapeutics for the treatment of Duchenne muscular dystrophy. Clinical pharmacology and therapeutics. vol 100. issue 2. 2017-04-28. PMID:27071500. |
for the last 20 years, the major goal in the development of therapeutic approaches to alleviate muscle weakness in dmd has been centered on the restoration of dystrophin or proteins that are analogous to dystrophin, such as utrophin, through a variety of modalities including cell therapy, gene therapy, gene correction, and the highly promising techniques utilizing crispr/cas9 technology. |
2017-04-28 |
2023-08-13 |
Not clear |
| Hiroshi Yajima, Kiyoshi Kawakam. Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice. Development, growth & differentiation. vol 58. issue 6. 2017-02-08. PMID:27224259. |
although grip strength was comparable in six4(+/-) 5(+/-) dmd(mdx) /y and dmd(mdx) /y mice, treadmill exercise did not induce muscle weakness in six4(+/-) 5(+/-) dmd(mdx) /y mice, suggesting higher regeneration capacity. |
2017-02-08 |
2023-08-13 |
mouse |
| Riccardo Papa, Francesca Madia, Domenico Bartolomeo, Federica Trucco, Marina Pedemonte, Monica Traverso, Paolo Broda, Claudio Bruno, Federico Zara, Carlo Minetti, Chiara Fiorill. Genetic and Early Clinical Manifestations of Females Heterozygous for Duchenne/Becker Muscular Dystrophy. Pediatric neurology. vol 55. 2016-12-14. PMID:26718981. |
female carriers of duchenne muscular dystrophy (dmd), although usually asymptomatic, develop muscle weakness up to 17% of the time, and a third present cardiac abnormalities or cognitive impairment. |
2016-12-14 |
2023-08-13 |
Not clear |
| Won Ho Kong, Dong Kyung Sung, Hyemin Kim, Jeong-A Yang, Nicholas Ieronimakis, Ki Su Kim, Jeehun Lee, Deok-Ho Kim, Seok Hyun Yun, Sei Kwang Hah. Self-adjuvanted hyaluronate--antigenic peptide conjugate for transdermal treatment of muscular dystrophy. Biomaterials. vol 81. 2016-10-14. PMID:26724457. |
duchenne's muscular dystrophy (dmd) is a neuromuscular disorder accompanied with muscle weakness and wasting. |
2016-10-14 |
2023-08-13 |
mouse |
| Yuval Blat, Shachar Bla. Drug Discovery of Therapies for Duchenne Muscular Dystrophy. Journal of biomolecular screening. vol 20. issue 10. 2016-10-05. PMID:25975656. |
duchenne muscular dystrophy (dmd) is a genetic, lethal, muscle disorder caused by the loss of the muscle protein, dystrophin, leading to progressive loss of muscle fibers and muscle weakness. |
2016-10-05 |
2023-08-13 |
Not clear |
| Michel Toussaint, Kurt Pernet, Marc Steens, Jurn Haan, Nicole Sheer. Cough Augmentation in Subjects With Duchenne Muscular Dystrophy: Comparison of Air Stacking via a Resuscitator Bag Versus Mechanical Ventilation. Respiratory care. vol 61. issue 1. 2016-09-23. PMID:26443018. |
air stacking improves cough effectiveness in people with duchenne muscular dystrophy (dmd) and respiratory muscle weakness. |
2016-09-23 |
2023-08-13 |
human |
| Zachary Stelter, Jana Strakova, Amritha Yellamilli, Kaleb Fischer, Katharine Sharpe, DeWayne Townsen. Hypoxia-induced cardiac injury in dystrophic mice. American journal of physiology. Heart and circulatory physiology. vol 310. issue 7. 2016-08-19. PMID:26851247. |
duchenne muscular dystrophy (dmd) is a disease of progressive destruction of striated muscle, resulting in muscle weakness with progressive respiratory and cardiac failure. |
2016-08-19 |
2023-08-13 |
mouse |
| Jean K Ma. Current and emerging treatment strategies for Duchenne muscular dystrophy. Neuropsychiatric disease and treatment. vol 12. 2016-08-15. PMID:27524897. |
it is caused by mutations of the dmd gene, leading to progressive muscle weakness, loss of independent ambulation by early teens, and premature death due to cardiorespiratory complications. |
2016-08-15 |
2023-08-13 |
Not clear |
| Cathleen Buckon, Susan Sienko, Anita Bagley, Mitell Sison-Williamson, Eileen Fowler, Loretta Staudt, Kent Heberer, Craig M McDonald, Michael Sussma. Can Quantitative Muscle Strength and Functional Motor Ability Differentiate the Influence of Age and Corticosteroids in Ambulatory Boys with Duchenne Muscular Dystrophy? PLoS currents. vol 8. 2016-08-08. PMID:27500011. |
in the absence of a curative treatment for duchenne muscular dystrophy (dmd), corticosteroid therapy (prednisone, deflazacort) has been adopted as the standard of care, as it slows the progression of muscle weakness and enables longer retention of functional mobility. |
2016-08-08 |
2023-08-13 |
Not clear |
| Takashi Iwase, Shoichiro Takao, Masashi Akaike, Katsuhito Adachi, Yuka Sumitomo-Ueda, Shusuke Yagi, Toshiyuki Niki, Kenya Kusunose, Noriko Tomita, Yoichiro Hirata, Koji Yamaguchi, Kunihiko Koshiba, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Ken-Ichi Aihara, Masafumi Harada, Hiromu Nishitani, Masataka Sat. Diagnostic utility of cardiac magnetic resonance for detection of cardiac involvement in female carriers of Duchenne muscular dystrophy. Heart Asia. vol 2. issue 1. 2016-06-21. PMID:27325943. |
since segmental or global left ventricle (lv) wall motion abnormalities in dmd carriers can arise even without apparent muscle weakness, it is difficult to differentiate cardiac involvement of a dmd carrier from other heart diseases in a non-invasive manner. |
2016-06-21 |
2023-08-13 |
Not clear |