| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicola Laws, Andrew Hoe. Progression of kyphosis in mdx mice. Journal of applied physiology (Bethesda, Md. : 1985). vol 97. issue 5. 2005-02-25. PMID:15234960. |
we hypothesize that paraspinal and respiratory muscle weakness and fibrosis are associated with the progression of spinal deformity in this mouse model, and similar to dmd patients there is evidence of altered thoracic conformation and area. |
2005-02-25 |
2023-08-12 |
mouse |
| David Touboul, Hélène Piednoël, Vincent Voisin, Sabine De La Porte, Alain Brunelle, Frédéric Halgand, Olivier Laprévot. Changes of phospholipid composition within the dystrophic muscle by matrix-assisted laser desorption/ionization mass spectrometry and mass spectrometry imaging. European journal of mass spectrometry (Chichester, England). vol 10. issue 5. 2005-01-04. PMID:15531799. |
duchenne muscular dystrophy (dmd) is a neuromuscular disease linked to the lack of the dystrophin, a submembrane protein, leading to muscle weakness and associated with a defect of the lipid metabolism. |
2005-01-04 |
2023-08-12 |
mouse |
| Akitoshi Miyamoto, Kazumi Taguchi, Soutaro Hieda, Mitsuru Kawamura, Kunihiko Fukuchi, Kunihide Gom. [Detection of micro mutation in dystrophin gene of DMD female carrier]. Rinsho byori. The Japanese journal of clinical pathology. vol 52. issue 6. 2004-08-20. PMID:15283161. |
we attempted to identify a mutation in dystrophin gene in a female patient who was suspected a duchenne muscular dystrophy (dmd) carrier with muscle weakness of upper limbs and congestive heart failure. |
2004-08-20 |
2023-08-12 |
Not clear |
| Johnny Huard, Baohong Cao, Zhuqing Qu-Peterse. Muscle-derived stem cells: potential for muscle regeneration. Birth defects research. Part C, Embryo today : reviews. vol 69. issue 3. 2004-04-30. PMID:14671776. |
duchenne muscular dystrophy (dmd) is a devastating x-linked muscle disease characterized by progressive muscle weakness caused by the lack of dystrophin expression at the sarcolemma of muscle fibers. |
2004-04-30 |
2023-08-12 |
Not clear |
| Johnny Huard, Baohong Cao, Zhuqing Qu-Peterse. Muscle-derived stem cells: potential for muscle regeneration. Birth defects research. Part C, Embryo today : reviews. vol 69. issue 3. 2004-04-30. PMID:14671776. |
we also describe the remarkable ability of stem cells to regenerate skeletal muscle and their potential use to alleviate the muscle weakness associated with dmd. |
2004-04-30 |
2023-08-12 |
Not clear |
| J T den Dunnen, M de Visser, E Bakke. [From gene to disease; the dystrophin gene involved in Duchenne and Becker muscular dystrophy]. Nederlands tijdschrift voor geneeskunde. vol 146. issue 8. 2002-07-10. PMID:11887623. |
bmd, a more varying phenotype which may overlap with limb girdle muscular dystrophy (lgmd), has a less severe muscle weakness which starts later than in dmd patients. |
2002-07-10 |
2023-08-12 |
Not clear |
| J T den Dunnen, M de Visser, E Bakke. [From gene to disease; the dystrophin gene involved in Duchenne and Becker muscular dystrophy]. Nederlands tijdschrift voor geneeskunde. vol 146. issue 8. 2002-07-10. PMID:11887623. |
dmd carriers may show some muscle weakness. |
2002-07-10 |
2023-08-12 |
Not clear |
| C Cornu, F Goubel, M Fardea. Muscle and joint elastic properties during elbow flexion in Duchenne muscular dystrophy. The Journal of physiology. vol 533. issue Pt 2. 2001-08-02. PMID:11389216. |
in addition, increases in stiffness were more marked in dmd patients exhibiting high levels of muscle weakness. |
2001-08-02 |
2023-08-12 |
human |
| E M Hoogerwaard, E Bakker, P F Ippel, J C Oosterwijk, D F Majoor-Krakauer, N J Leschot, A J Van Essen, H G Brunner, P A van der Wouw, A A Wilde, M de Visse. Signs and symptoms of Duchenne muscular dystrophy and Becker muscular dystrophy among carriers in The Netherlands: a cohort study. Lancet (London, England). vol 353. issue 9170. 1999-07-09. PMID:10382696. |
carriers of duchenne muscular dystrophy (dmd) and becker muscular dystrophy (bmd) may show muscle weakness or dilated cardiomyopathy. |
1999-07-09 |
2023-08-12 |
Not clear |
| A von Moers, F K van Landeghem, R D Cohn, E Baumgarten, J Bürger, G Stoltenburg-Didinge. Dystrophinopathy in a boy with Chediak-Higashi syndrome. Neuromuscular disorders : NMD. vol 8. issue 7. 1999-02-04. PMID:9829279. |
unusual for both chs and dmd muscle weakness and hypotonia became evident during the first months of life. |
1999-02-04 |
2023-08-12 |
Not clear |
| J A Rafael, J M Tinsley, A C Potter, A E Deconinck, K E Davie. Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice. Nature genetics. vol 19. issue 1. 1998-05-29. PMID:9590295. |
mice deficient for both dystrophin and the dystrophin-related protein, utrophin, (dmd(mdx);utrn-/- mice) die between 6 and 20 weeks of age suffering from severe muscle weakness with joint contractures, pronounced growth retardation and kyphosis, suggesting that dystrophin and utrophin play complementary roles. |
1998-05-29 |
2023-08-12 |
mouse |
| R Forst, J Forst, K D Heller, K Hengstle. [Characteristics in the treatment of scoliosis in muscular diseases]. Zeitschrift fur Orthopadie und ihre Grenzgebiete. vol 135. issue 2. 1997-07-10. PMID:9214180. |
patients suffering from the most frequent muscle disorders duchenne muscular dystrophy (dmd) and spinal muscular atrophies (sma), who ceased walking respectively are confined from the outset to the wheel-chair, are developing commonly a progressive scoliosis (collapsing spine) due to an increasing muscle weakness. |
1997-07-10 |
2023-08-12 |
Not clear |
| K Ogata, S Kohno, T Komiya, K Yatabe, M Kawa. [Different mechanism may underlie respiratory failure of myotonic and Duchenne muscular dystrophies--a pulseoxymetric and spirometric study]. Rinsho shinkeigaku = Clinical neurology. vol 36. issue 7. 1997-01-21. PMID:8952351. |
we studied the relationship between nocturnal hypoxemia and respiratory muscle weakness by nocturnal pulseoxymetry and spirometry in two major hereditary myopathies, myotonic and duchenne muscular dystrophies (md and dmd respectively). |
1997-01-21 |
2023-08-12 |
Not clear |
| K Ogata, S Kohno, T Komiya, K Yatabe, M Kawa. [Different mechanism may underlie respiratory failure of myotonic and Duchenne muscular dystrophies--a pulseoxymetric and spirometric study]. Rinsho shinkeigaku = Clinical neurology. vol 36. issue 7. 1997-01-21. PMID:8952351. |
therefore, we conclude respiratory muscle weakness is a single important factor which determines the severity of respiratory failure in dmd, while another/other factor (s), such as disturbance of respiratory control or myotonia, may play an important role in md. |
1997-01-21 |
2023-08-12 |
Not clear |
| T Takasugi, T Ishihara, J Kawamura, T Kawashir. [Respiratory failure: respiratory disorder during sleep in patients with myotonic dystrophy]. Rinsho shinkeigaku = Clinical neurology. vol 35. issue 12. 1996-12-04. PMID:8752439. |
we concluded that respiratory failure in patients with myd would be attributed to respiratory center disorder rather than respiratory muscle weakness, which is the main cause of respiratory failure in patients with dmd. |
1996-12-04 |
2023-08-12 |
Not clear |
| T Takasugi, T Ishihara, J Kawamura, K Sasaki, T Toyoda, M Oosumi, T Aoyagi, T Kawashir. [Respiratory disorders during sleep in Duchenne muscular dystrophy]. Nihon Kyobu Shikkan Gakkai zasshi. vol 33. issue 8. 1995-12-12. PMID:7474561. |
in the patients with advanced dmd, blood gas analysis showed hypercapnia, and the index of central sleep apnea was high, probably because of respiratory muscle weakness or abnormalities in the respiratory center. |
1995-12-12 |
2023-08-12 |
Not clear |
| M Saito, H Kawai, K Adachi, M Akaik. [Clinical feature and mechanism of cardiac failure in patients with Becker muscular dystrophy]. Rinsho shinkeigaku = Clinical neurology. vol 34. issue 2. 1994-06-24. PMID:8194265. |
the ratio of ejection time to pre-ejection period (et/pep) decreased to 2.0-3.3 in bmd, and was significantly lower than that in dmd patients with comparable muscle weakness. |
1994-06-24 |
2023-08-12 |
Not clear |
| A D Gurusinghe, M C Wilce, L Austin, M T Hear. Duchenne muscular dystrophy and dystrophin: sequence homology observations. Neurochemical research. vol 16. issue 6. 1992-04-02. PMID:1791914. |
duchenne muscular dystrophy (dmd) is a genetically transmitted disease characterized by progressive muscle weakness and usually leads to death. |
1992-04-02 |
2023-08-11 |
Not clear |
| K McCully, U Giger, Z Argov, B Valentine, B Cooper, B Chance, W Ban. Canine X-linked muscular dystrophy studied with in vivo phosphorus magnetic resonance spectroscopy. Muscle & nerve. vol 14. issue 11. 1992-01-16. PMID:1745283. |
duchenne muscular dystrophy (dmd) is an x-linked disease characterized by progressive muscle weakness and degeneration. |
1992-01-16 |
2023-08-11 |
Not clear |
| M Saitoh, H Miyakoda, H Kitamura, S Kasagi, H Takakur. [Clinical significance of serum cardiac myosin light chain I in patients with muscular dystrophy]. Rinsho shinkeigaku = Clinical neurology. vol 30. issue 8. 1991-01-24. PMID:2253417. |
all patients with dmd and fcmd showed moderate or severe skeletal muscle weakness. |
1991-01-24 |
2023-08-11 |
human |