| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wanda M Snow, Judy E Anderson, Lorna S Jakobso. Neuropsychological and neurobehavioral functioning in Duchenne muscular dystrophy: a review. Neuroscience and biobehavioral reviews. vol 37. issue 5. 2014-01-03. PMID:23545331. |
duchenne muscular dystrophy (dmd) is a genetic condition affecting predominantly boys that is characterized by fatal muscle weakness. |
2014-01-03 |
2023-08-12 |
Not clear |
| Genevieve C Kendall, Ekaterina I Mokhonova, Miriana Moran, Natalia E Sejbuk, Derek W Wang, Oscar Silva, Richard T Wang, Leonel Martinez, Qi L Lu, Robert Damoiseaux, Melissa J Spencer, Stanley F Nelson, M Carrie Micel. Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy. Science translational medicine. vol 4. issue 164. 2013-09-16. PMID:23241744. |
duchenne muscular dystrophy (dmd) causes profound and progressive muscle weakness and loss, resulting in early death. |
2013-09-16 |
2023-08-12 |
mouse |
| Maaike van Putten, Margriet Hulsker, Courtney Young, Vishna D Nadarajah, Hans Heemskerk, Louise van der Weerd, Peter A C 't Hoen, Gert-Jan B van Ommen, Annemieke M Aartsma-Ru. Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double-knockout mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 6. 2013-08-02. PMID:23460734. |
mdx/utrn(-/-) mice develop severe muscle weakness, kyphosis, respiratory and heart failure, and premature death closely resembling dmd pathology. |
2013-08-02 |
2023-08-12 |
mouse |
| E Rizzuto, A Catizone, A Musarò, Z Del Pret. Dystrophic tendon functionality is recovered by muscle-specific expression of insulin-like growth factor in mdx mice. Journal of biomechanics. vol 46. issue 3. 2013-07-01. PMID:23122221. |
duchenne muscular dystrophy (dmd) is a severe genetic disorder of skeletal muscle, characterized by a steady muscle weakness. |
2013-07-01 |
2023-08-12 |
mouse |
| Andreas Buttgereit, Cornelia Weber, Christoph S Garbe, Oliver Friedric. From chaos to split-ups--SHG microscopy reveals a specific remodelling mechanism in ageing dystrophic muscle. The Journal of pathology. vol 229. issue 3. 2013-03-19. PMID:23132094. |
duchenne muscular dystrophy (dmd) is a common inherited muscle disease showing chronic inflammation and progressive muscle weakness. |
2013-03-19 |
2023-08-12 |
mouse |
| Julia von Maltzahn, Jean-Marc Renaud, Gianni Parise, Michael A Rudnick. Wnt7a treatment ameliorates muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 50. 2013-02-28. PMID:23185011. |
duchenne muscular dystrophy (dmd) is a devastating genetic muscular disorder of childhood marked by progressive debilitating muscle weakness and wasting, and ultimately death in the second or third decade of life. |
2013-02-28 |
2023-08-12 |
mouse |
| Marion Pauly, Frederic Daussin, Yan Burelle, Tong Li, Richard Godin, Jeremy Fauconnier, Christelle Koechlin-Ramonatxo, Gerald Hugon, Alain Lacampagne, Marjorie Coisy-Quivy, Feng Liang, Sabah Hussain, Stefan Matecki, Basil J Petro. AMPK activation stimulates autophagy and ameliorates muscular dystrophy in the mdx mouse diaphragm. The American journal of pathology. vol 181. issue 2. 2012-11-26. PMID:22683340. |
duchenne muscular dystrophy (dmd) is characterized by myofiber death from apoptosis or necrosis, leading in many patients to fatal respiratory muscle weakness. |
2012-11-26 |
2023-08-12 |
mouse |
| Justin M Percival, Nicholas P Whitehead, Marvin E Adams, Candace M Adamo, Joseph A Beavo, Stanley C Froehne. Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy. The Journal of pathology. vol 228. issue 1. 2012-10-09. PMID:22653783. |
we report here that a 14-week treatment of the mdx mouse model of dmd with the pde5 inhibitor sildenafil (viagra(®), revatio(®)) significantly reduced mdx diaphragm muscle weakness without impacting fatigue resistance. |
2012-10-09 |
2023-08-12 |
mouse |
| Stefan M Gehrig, Chris van der Poel, Timothy A Sayer, Jonathan D Schertzer, Darren C Henstridge, Jarrod E Church, Severine Lamon, Aaron P Russell, Kay E Davies, Mark A Febbraio, Gordon S Lync. Hsp72 preserves muscle function and slows progression of severe muscular dystrophy. Nature. vol 484. issue 7394. 2012-05-25. PMID:22495301. |
in dko mice, a phenocopy of dmd that results in severe spinal curvature (kyphosis), muscle weakness and premature death, bgp-15 decreased kyphosis, improved the dystrophic pathophysiology in limb and diaphragm muscles and extended lifespan. |
2012-05-25 |
2023-08-12 |
mouse |
| Rakshita A Charan, Ryan Hanson, Paula R Clemen. Deubiquitinating enzyme A20 negatively regulates NF-κB signaling in skeletal muscle in mdx mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 2. 2012-04-09. PMID:22012122. |
as a result, dmd causes progressive limb muscle weakness and cardiac and respiratory failure. |
2012-04-09 |
2023-08-12 |
mouse |
| Alexander Spassov, Tomasz Gredes, Tomasz Gedrange, Silke Lucke, Sven Morgenstern, Dragan Pavlovic, Christiane Kunert-Kei. Differential expression of myosin heavy chain isoforms in the masticatory muscles of dystrophin-deficient mice. European journal of orthodontics. vol 33. issue 6. 2012-04-04. PMID:21187529. |
the dystrophin-deficient mouse (mdx) is a homologue animal model of duchenne muscular dystrophy (dmd) and is characterized by slowly progressive muscle weakness accompanied by changes in myosin heavy chain (myhc) composition. |
2012-04-04 |
2023-08-12 |
mouse |
| Christiane Kunert-Keil, Tomasz Gredes, Silke Lucke, Sven Morgenstern, Agnieszka Mielczarek, Katarzyna Sporniak-Tutak, Tomasz Gedrange, Alexander Spasso. Caveolin-1, caveolin-3 and VEGF expression in the masticatory muscles of mdx mice. Folia histochemica et cytobiologica. vol 49. issue 2. 2011-10-27. PMID:21744331. |
duchenne muscular dystrophy (dmd) and murine x-linked muscular dystrophy (mdx), its murine model, are characterized by muscle damage and muscle weakness associated with inflammation and new vessel formation. |
2011-10-27 |
2023-08-12 |
mouse |
| Nina Tsakadze, Lara W Katzin, Sendhil Krishnan, Réza Behrou. Cerebral infarction in Duchenne muscular dystrophy. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 20. issue 3. 2011-09-06. PMID:20621521. |
duchenne muscular dystrophy (dmd) is an x-linked form of muscular dystrophy characterized by progressive limb-girdle distribution of muscle weakness. |
2011-09-06 |
2023-08-12 |
Not clear |
| Claudia Del Tongo, Donatella Carretta, Gianluca Fulgenzi, Claudio Catini, Diego Minciacch. Parvalbumin-positive GABAergic interneurons are increased in the dorsal hippocampus of the dystrophic mdx mouse. Acta neuropathologica. vol 118. issue 6. 2011-07-04. PMID:19588159. |
duchenne muscular dystrophy (dmd) is characterized by variable alterations of the dystrophin gene and by muscle weakness and cognitive impairment. |
2011-07-04 |
2023-08-12 |
mouse |
| Tae-Jin Song, Kyung-A Lee, Seong-Woong Kang, Hanna Cho, Young-Chul Cho. Three cases of manifesting female carriers in patients with Duchenne muscular dystrophy. Yonsei medical journal. vol 52. issue 1. 2011-05-03. PMID:21155054. |
approximately 8% of female duchenne muscular dystrophy (dmd) carriers are manifesting carriers and have muscle weakness to some extent. |
2011-05-03 |
2023-08-12 |
Not clear |
| Nathaly Gaudreault, Denis Gravel, Sylvie Nadeau, Sylvie Houde, Denis Gagno. Gait patterns comparison of children with Duchenne muscular dystrophy to those of control subjects considering the effect of gait velocity. Gait & posture. vol 32. issue 3. 2011-01-24. PMID:20599384. |
these results suggest that most of the modifications observed are strategies used by children with dmd to cope with possible muscle weakness in order to provide support, propulsion and balance of the body during gait. |
2011-01-24 |
2023-08-12 |
human |
| Kumaran Chandrasekharan, Jung Hae Yoon, Ying Xu, Sarah deVries, Marybeth Camboni, Paulus M L Janssen, Ajit Varki, Paul T Marti. A human-specific deletion in mouse Cmah increases disease severity in the mdx model of Duchenne muscular dystrophy. Science translational medicine. vol 2. issue 42. 2010-11-15. PMID:20668298. |
this is especially true for the loss of ambulation, cardiac and respiratory muscle weakness, and decreased life span, all of which are major phenotypes contributing to dmd morbidity and mortality. |
2010-11-15 |
2023-08-12 |
mouse |
| Mirella Meregalli, Andrea Farini, Daniele Parolini, Simona Maciotta, Yvan Torrent. Stem cell therapies to treat muscular dystrophy: progress to date. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. vol 24. issue 4. 2010-10-05. PMID:20623990. |
dmd patients exhibit progressive muscle weakness and atrophy followed by exhaustion of muscular regenerative capacity, fibrosis, and eventually disruption of the muscle tissue architecture. |
2010-10-05 |
2023-08-12 |
human |
| Alexander Spassov, Tomasz Gredes, Tomasz Gedrange, Silke Lucke, Dragan Pavlovic, Christiane Kunert-Kei. Histological changes in masticatory muscles of mdx mice. Archives of oral biology. vol 55. issue 4. 2010-07-15. PMID:20207343. |
skeletal muscles of dmd patients and those of murine model of dmd - mdx mice - are both characterized by ca(2+) induced muscle damage, muscle weakness and characteristic histological changes. |
2010-07-15 |
2023-08-12 |
mouse |
| Eder Zucconi, Marcos Costa Valadares, Natássia M Vieira, Carlos R Bueno, Mariane Secco, Tatiana Jazedje, Helga Cristina Almeida da Silva, Mariz Vainzof, Mayana Zat. Ringo: discordance between the molecular and clinical manifestation in a golden retriever muscular dystrophy dog. Neuromuscular disorders : NMD. vol 20. issue 1. 2010-04-20. PMID:19944604. |
of the various genetic homologues to duchenne muscular dystrophy (dmd), the golden retriever muscular dystrophy (grmd) dog, which presents a variable but usually severe and progressive muscle weakness, has the closest relevance to dmd in both clinical severity and histopathological change. |
2010-04-20 |
2023-08-12 |
dog |