| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irina T Zaharieva, Mattia Calissano, Mariacristina Scoto, Mark Preston, Sebahattin Cirak, Lucy Feng, James Collins, Ryszard Kole, Michela Guglieri, Volker Straub, Kate Bushby, Alessandra Ferlini, Jennifer E Morgan, Francesco Munton. Dystromirs as serum biomarkers for monitoring the disease severity in Duchenne muscular Dystrophy. PloS one. vol 8. issue 11. 2015-01-02. PMID:24282529. |
although longer term studies are needed to clarify the relationship between dystrophin restoration following therapeutic intervention and the level of circulating mirnas, our results indicate that mir-1 and mir-133 can be considered as exploratory biomarkers for monitoring the progression of muscle weakness and indirectly the remaining muscle mass in dmd. |
2015-01-02 |
2023-08-12 |
Not clear |
| C H Kunert-Keil, T Gredes, S Lucke, U Botzenhart, M Dominiak, T Gedrang. Differential expression of genes involved in the calcium homeostasis in masticatory muscles of MDX mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 65. issue 2. 2014-12-16. PMID:24781740. |
duchenne muscular dystrophy (dmd) and its murine model, mdx, are characterized by ca(2+) induced muscle damage and muscle weakness followed by distorted dentofacial morphology. |
2014-12-16 |
2023-08-13 |
mouse |
| Nathalie Doorenweerd, Chiara S Straathof, Eve M Dumas, Pietro Spitali, Ieke B Ginjaar, Beatrijs H Wokke, Debby G Schrans, Janneke C van den Bergen, Erik W van Zwet, Andrew Webb, Mark A van Buchem, Jan J Verschuuren, Jos G Hendriksen, Erik H Niks, Hermien E Ka. Reduced cerebral gray matter and altered white matter in boys with Duchenne muscular dystrophy. Annals of neurology. vol 76. issue 3. 2014-12-10. PMID:25043804. |
duchenne muscular dystrophy (dmd) is characterized by progressive muscle weakness caused by dmd gene mutations leading to absence of the full-length dystrophin protein in muscle. |
2014-12-10 |
2023-08-13 |
Not clear |
| Sonia Khirani, Adriana Ramirez, Guillaume Aubertin, Michèle Boulé, Chrystelle Chemouny, Véronique Forin, Brigitte Faurou. Respiratory muscle decline in Duchenne muscular dystrophy. Pediatric pulmonology. vol 49. issue 5. 2014-12-04. PMID:23836708. |
duchenne muscular dystrophy (dmd) causes progressive respiratory muscle weakness. |
2014-12-04 |
2023-08-12 |
Not clear |
| Norio Motohashi, Atsushi Asakur. Muscle satellite cell heterogeneity and self-renewal. Frontiers in cell and developmental biology. vol 2. 2014-11-03. PMID:25364710. |
additionally, in duchenne muscular dystrophy (dmd) patients, the loss of satellite cell regenerative capacity and decreased satellite cell number due to continuous needs for satellite cells lead to progressive muscle weakness with chronic degeneration. |
2014-11-03 |
2023-08-13 |
Not clear |
| Thomas D Ryan, John L Jefferies, Hemant Sawnani, Brenda L Wong, Aimee Gardner, Megan Del Corral, Angela Lorts, David L S Morale. Implantation of the HeartMate II and HeartWare left ventricular assist devices in patients with duchenne muscular dystrophy: lessons learned from the first applications. ASAIO journal (American Society for Artificial Internal Organs : 1992). vol 60. issue 2. 2014-10-24. PMID:24577373. |
duchenne muscular dystrophy (dmd) is an x-linked recessive disorder affecting 1 in 3,500 males, characterized by progressive skeletal muscle weakness and death secondary to cardiac or respiratory failure in the 2nd or 3rd decade. |
2014-10-24 |
2023-08-12 |
Not clear |
| Paul M L Janssen, Jason D Murray, Kevin E Schill, Neha Rastogi, Eric J Schultz, Tam Tran, Subha V Raman, Jill A Rafael-Fortne. Prednisolone attenuates improvement of cardiac and skeletal contractile function and histopathology by lisinopril and spironolactone in the mdx mouse model of Duchenne muscular dystrophy. PloS one. vol 9. issue 2. 2014-10-14. PMID:24551095. |
duchenne muscular dystrophy (dmd) is an inherited disease that causes striated muscle weakness. |
2014-10-14 |
2023-08-12 |
mouse |
| Chengzu Long, John R McAnally, John M Shelton, Alex A Mireault, Rhonda Bassel-Duby, Eric N Olso. Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA. Science (New York, N.Y.). vol 345. issue 6201. 2014-09-22. PMID:25123483. |
dmd is characterized by progressive muscle weakness and a shortened life span, and there is no effective treatment. |
2014-09-22 |
2023-08-13 |
mouse |
| Susan Jarmin, Hanna Kymalainen, Linda Popplewell, George Dickso. New developments in the use of gene therapy to treat Duchenne muscular dystrophy. Expert opinion on biological therapy. vol 14. issue 2. 2014-09-18. PMID:24308293. |
duchenne muscular dystrophy (dmd) is a lethal x-linked inherited disorder characterised by progressive muscle weakness, wasting and degeneration. |
2014-09-18 |
2023-08-12 |
Not clear |
| Rana Abou-Khalil, Frank Yang, Marie Mortreux, Shirley Lieu, Yan-Yiu Yu, Maud Wurmser, Catia Pereira, Frédéric Relaix, Theodore Miclau, Ralph S Marcucio, Céline Colno. Delayed bone regeneration is linked to chronic inflammation in murine muscular dystrophy. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 29. issue 2. 2014-09-04. PMID:23857747. |
duchenne muscular dystrophy (dmd) patients exhibit skeletal muscle weakness with continuous cycles of muscle fiber degeneration/regeneration, chronic inflammation, low bone mineral density, and increased risks of fracture. |
2014-09-04 |
2023-08-12 |
mouse |
| Elisa Negroni, Emilie Henault, Fabien Chevalier, Marie Gilbert-Sirieix, Toin H Van Kuppevelt, Dulce Papy-Garcia, Georges Uzan, Patricia Albanes. Glycosaminoglycan modifications in Duchenne muscular dystrophy: specific remodeling of chondroitin sulfate/dermatan sulfate. Journal of neuropathology and experimental neurology. vol 73. issue 8. 2014-09-02. PMID:25003237. |
widespread skeletal muscle degeneration and impaired regeneration lead to progressive muscle weakness and premature death in patients with duchenne muscular dystrophy (dmd). |
2014-09-02 |
2023-08-13 |
Not clear |
| Clara De Palma, Cristiana Perrotta, Paolo Pellegrino, Emilio Clementi, Davide Cervi. Skeletal muscle homeostasis in duchenne muscular dystrophy: modulating autophagy as a promising therapeutic strategy. Frontiers in aging neuroscience. vol 6. 2014-08-08. PMID:25104934. |
in duchenne muscular dystrophy (dmd), the most severe form of these diseases, the mutations in the dystrophin gene lead to muscle weakness and wasting, exhaustion of muscular regenerative capacity, and chronic local inflammation leading to substitution of myofibers by connective and adipose tissue. |
2014-08-08 |
2023-08-13 |
Not clear |
| Guqi Wang, Qilong L. A nitrate ester of sedative alkyl alcohol improves muscle function and structure in a murine model of Duchenne muscular dystrophy. Molecular pharmaceutics. vol 10. issue 10. 2014-05-22. PMID:23924275. |
abnormal no signaling at the sarcolemmal level is integrally involved in the pathogenesis and accounts, at least in part, for the muscle weakness of dmd. |
2014-05-22 |
2023-08-12 |
mouse |
| Xaver Koenig, Lena Rubi, Gerald J Obermair, Rene Cervenka, Xuan B Dang, Peter Lukacs, Stefan Kummer, Reginald E Bittner, Helmut Kubista, Hannes Todt, Karlheinz Hilbe. Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart. American journal of physiology. Heart and circulatory physiology. vol 306. issue 4. 2014-05-01. PMID:24337461. |
duchenne muscular dystrophy (dmd), induced by mutations in the gene encoding for the cytoskeletal protein dystrophin, is an inherited disease characterized by progressive muscle weakness. |
2014-05-01 |
2023-08-12 |
mouse |
| Nikolai Klymiuk, Andreas Blutke, Alexander Graf, Sabine Krause, Katinka Burkhardt, Annegret Wuensch, Stefan Krebs, Barbara Kessler, Valeri Zakhartchenko, Mayuko Kurome, Elisabeth Kemter, Hiroshi Nagashima, Benedikt Schoser, Nadja Herbach, Helmut Blum, Rüdiger Wanke, Annemieke Aartsma-Rus, Christian Thirion, Hanns Lochmüller, Maggie C Walter, Eckhard Wol. Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle. Human molecular genetics. vol 22. issue 21. 2014-04-30. PMID:23784375. |
dmd pigs exhibit absence of dystrophin in skeletal muscles, increased serum creatine kinase levels, progressive dystrophic changes of skeletal muscles, impaired mobility, muscle weakness and a maximum life span of 3 months due to respiratory impairment. |
2014-04-30 |
2023-08-12 |
human |
| Wanda M Snow, Judy E Anderson, Lorna S Jakobso. Neuropsychological and neurobehavioral functioning in Duchenne muscular dystrophy: a review. Neuroscience and biobehavioral reviews. vol 37. issue 5. 2014-01-03. PMID:23545331. |
duchenne muscular dystrophy (dmd) is a genetic condition affecting predominantly boys that is characterized by fatal muscle weakness. |
2014-01-03 |
2023-08-12 |
Not clear |
| Genevieve C Kendall, Ekaterina I Mokhonova, Miriana Moran, Natalia E Sejbuk, Derek W Wang, Oscar Silva, Richard T Wang, Leonel Martinez, Qi L Lu, Robert Damoiseaux, Melissa J Spencer, Stanley F Nelson, M Carrie Micel. Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy. Science translational medicine. vol 4. issue 164. 2013-09-16. PMID:23241744. |
duchenne muscular dystrophy (dmd) causes profound and progressive muscle weakness and loss, resulting in early death. |
2013-09-16 |
2023-08-12 |
mouse |
| Maaike van Putten, Margriet Hulsker, Courtney Young, Vishna D Nadarajah, Hans Heemskerk, Louise van der Weerd, Peter A C 't Hoen, Gert-Jan B van Ommen, Annemieke M Aartsma-Ru. Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double-knockout mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 6. 2013-08-02. PMID:23460734. |
mdx/utrn(-/-) mice develop severe muscle weakness, kyphosis, respiratory and heart failure, and premature death closely resembling dmd pathology. |
2013-08-02 |
2023-08-12 |
mouse |
| E Rizzuto, A Catizone, A Musarò, Z Del Pret. Dystrophic tendon functionality is recovered by muscle-specific expression of insulin-like growth factor in mdx mice. Journal of biomechanics. vol 46. issue 3. 2013-07-01. PMID:23122221. |
duchenne muscular dystrophy (dmd) is a severe genetic disorder of skeletal muscle, characterized by a steady muscle weakness. |
2013-07-01 |
2023-08-12 |
mouse |
| Andreas Buttgereit, Cornelia Weber, Christoph S Garbe, Oliver Friedric. From chaos to split-ups--SHG microscopy reveals a specific remodelling mechanism in ageing dystrophic muscle. The Journal of pathology. vol 229. issue 3. 2013-03-19. PMID:23132094. |
duchenne muscular dystrophy (dmd) is a common inherited muscle disease showing chronic inflammation and progressive muscle weakness. |
2013-03-19 |
2023-08-12 |
mouse |