| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nico Teske, Annette Liessem, Felix Fischbach, Tim Clarner, Cordian Beyer, Christoph Wruck, Athanassios Fragoulis, Simone C Tauber, Marion Victor, Markus Kip. Chemical hypoxia-induced integrated stress response activation in oligodendrocytes is mediated by the transcription factor nuclear factor (erythroid-derived 2)-like 2 (NRF2). Journal of neurochemistry. vol 144. issue 3. 2019-03-01. PMID:29210072. |
this study provides strong evidence that oxidative stress in oligodendrocytes activates endoplasmic reticulum stress response in a nrf2-dependent manner and, in consequence, might regulate oligodendrocyte degeneration in multiple sclerosis and other neurological disorders. |
2019-03-01 |
2023-08-13 |
Not clear |
| Stefan Esser, Larissa Göpfrich, Kai Bihler, Eugenia Kress, Stella Nyamoya, Simone C Tauber, Tim Clarner, Matthias B Stope, Thomas Pufe, Markus Kipp, Lars-Ove Brandenbur. Toll-Like Receptor 2-Mediated Glial Cell Activation in a Mouse Model of Cuprizone-Induced Demyelination. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29288338. |
multiple sclerosis (ms) is a chronic degenerative disease of the central nervous system that is characterized by myelin abnormalities, oligodendrocyte pathology, and concomitant glia activation. |
2019-02-26 |
2023-08-13 |
mouse |
| Bin Xing, Lauren E Brink, Kelly Maers, Mara L Sullivan, Richard J Bodnar, Donna B Stolz, Franca Camb. Conditional depletion of GSK3b protects oligodendrocytes from apoptosis and lessens demyelination in the acute cuprizone model. Glia. vol 66. issue 9. 2019-02-12. PMID:29761559. |
apoptosis is recognized as the main mechanism of oligodendrocyte loss in multiple sclerosis caused either by immune mediated injury (barnett & prineas, ) or a direct degenerative process (oligodendrogliapathy; lucchinetti et al., ). |
2019-02-12 |
2023-08-13 |
Not clear |
| Elijah Koreman, Xiaowei Sun, Q Richard L. Chromatin remodeling and epigenetic regulation of oligodendrocyte myelination and myelin repair. Molecular and cellular neurosciences. vol 87. 2019-01-30. PMID:29254827. |
in this review, we will focus on epigenetic programming associated with histone modification enzymes, chromatin remodeling, and non-coding rnas that regulate oligodendrocyte lineage progression, and discuss how these mechanisms might be harnessed to induce myelin repair for treatment of demyelinating diseases such as multiple sclerosis. |
2019-01-30 |
2023-08-13 |
Not clear |
| Satoshi Kitagawa, Takashi Osada, Kimihiko Kaneko, Toshiyuki Takahashi, Norihiro Suzuki, Jin Nakahar. [Clinical analysis of opticospinal multiple sclerosis (OSMS) presentation detecting anti-myelin oligodendrocyte glycoprotein (MOG) antibody]. Rinsho shinkeigaku = Clinical neurology. vol 58. issue 12. 2019-01-30. PMID:30487359. |
[clinical analysis of opticospinal multiple sclerosis (osms) presentation detecting anti-myelin oligodendrocyte glycoprotein (mog) antibody]. |
2019-01-30 |
2023-08-13 |
Not clear |
| Fucheng Luo, Jessie Zhang, Kathryn Burke, Rita R Romito-DiGiacomo, Robert H Miller, Yan Yan. Oligodendrocyte-specific loss of Cdk5 disrupts the architecture of nodes of Ranvier as well as learning and memory. Experimental neurology. vol 306. 2019-01-28. PMID:29729246. |
the novel roles of cdk5 in oligodendrocyte lineage cells may provide insights for helping understand the cognitive changes sometimes seen in demyelinating diseases such as multiple sclerosis. |
2019-01-28 |
2023-08-13 |
mouse |
| Seok-Jin Choi, Boram Kim, Haeng-Jin Lee, Seong-Joon Kim, Sung-Min Kim, Jung-Joon Sun. Rebound of relapses after discontinuation of rituximab in a patient with MOG-IgG1 positive highly relapsing optic neuritis: a case report. BMC neurology. vol 18. issue 1. 2019-01-22. PMID:30577778. |
myelin oligodendrocyte glycoprotein immunoglobulin g1 (mog-igg1)-associated disease is suggested as a separate disease entity distinct from multiple sclerosis and neuromyelitis optica spectrum disorder. |
2019-01-22 |
2023-08-13 |
Not clear |
| Ferdinand Schweser, Ana Luiza Raffaini Duarte Martins, Jesper Hagemeier, Fuchun Lin, Jannis Hanspach, Bianca Weinstock-Guttman, Simon Hametner, Niels Bergsland, Michael G Dwyer, Robert Zivadino. Mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: A proposed mechanistic relationship between inflammation and oligodendrocyte vitality. NeuroImage. vol 167. 2018-11-08. PMID:29097315. |
mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: a proposed mechanistic relationship between inflammation and oligodendrocyte vitality. |
2018-11-08 |
2023-08-13 |
human |
| Brian Chiou, Elisabeth Lucassen, Michael Sather, Asha Kallianpur, James Conno. Semaphorin4A and H-ferritin utilize Tim-1 on human oligodendrocytes: A novel neuro-immune axis. Glia. vol 66. issue 7. 2018-11-05. PMID:29457657. |
furthermore, we show in a series of pilot studies that sema4a is detectable in the csf of multiple sclerosis patients and hiv-seropositive persons and can induce oligodendrocyte cell death. |
2018-11-05 |
2023-08-13 |
mouse |
| Ryo Ohtomo, Atsushi Iwata, Ken Ara. Molecular Mechanisms of Oligodendrocyte Regeneration in White Matter-Related Diseases. International journal of molecular sciences. vol 19. issue 6. 2018-10-09. PMID:29895784. |
in this review, we first overview basic mechanisms of interaction between oligodendrocyte lineage cells and neighboring cells, and then introduce how oligodendrogenesis occurs under the conditions of neurodegenerative diseases, focusing on vascular cognitive impairment syndrome, alzheimer’s disease, and multiple sclerosis. |
2018-10-09 |
2023-08-13 |
Not clear |
| Mohammadreza Semnani, Farhad Mashayekhi, Mahnaz Azarnia, Zivar Saleh. Effects of green tea epigallocatechin-3-gallate on the proteolipid protein and oligodendrocyte transcription factor 1 messenger RNA gene expression in a mouse model of multiple sclerosis. Folia neuropathologica. vol 55. issue 3. 2018-09-27. PMID:28984112. |
effects of green tea epigallocatechin-3-gallate on the proteolipid protein and oligodendrocyte transcription factor 1 messenger rna gene expression in a mouse model of multiple sclerosis. |
2018-09-27 |
2023-08-13 |
mouse |
| Elisa Romanelli, Doron Merkler, Aleksandra Mezydlo, Marie-Theres Weil, Martin S Weber, Ivana Nikić, Stephanie Potz, Edgar Meinl, Florian E H Matznick, Mario Kreutzfeldt, Alexander Ghanem, Karl-Klaus Conzelmann, Imke Metz, Wolfgang Brück, Matthew Routh, Mikael Simons, Derron Bishop, Thomas Misgeld, Martin Kerschensteine. Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model. Nature communications. vol 7. 2018-09-05. PMID:27848954. |
myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model. |
2018-09-05 |
2023-08-13 |
human |
| Elisa Romanelli, Doron Merkler, Aleksandra Mezydlo, Marie-Theres Weil, Martin S Weber, Ivana Nikić, Stephanie Potz, Edgar Meinl, Florian E H Matznick, Mario Kreutzfeldt, Alexander Ghanem, Karl-Klaus Conzelmann, Imke Metz, Wolfgang Brück, Matthew Routh, Mikael Simons, Derron Bishop, Thomas Misgeld, Martin Kerschensteine. Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model. Nature communications. vol 7. 2018-09-05. PMID:27848954. |
oligodendrocyte damage is a central event in the pathogenesis of the common neuroinflammatory condition, multiple sclerosis (ms). |
2018-09-05 |
2023-08-13 |
human |
| Maciej Jurynczyk, Fay Probert, Tianrong Yeo, George Tackley, Tim D W Claridge, Ana Cavey, Mark R Woodhall, Siddharth Arora, Torsten Winkler, Eric Schiffer, Angela Vincent, Gabriele DeLuca, Nicola R Sibson, M Isabel Leite, Patrick Waters, Daniel C Anthony, Jacqueline Palac. Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease. Acta neuropathologica communications. vol 5. issue 1. 2018-08-16. PMID:29208041. |
the overlapping clinical features of relapsing remitting multiple sclerosis (rrms), aquaporin-4 (aqp4)-antibody (ab) neuromyelitis optica spectrum disorder (nmosd), and myelin oligodendrocyte glycoprotein (mog)-ab disease mean that detection of disease specific serum antibodies is the gold standard in diagnostics. |
2018-08-16 |
2023-08-13 |
Not clear |
| Rafael E Flores-Obando, Mona M Freidin, Charles K Abram. Rapid and Specific Immunomagnetic Isolation of Mouse Primary Oligodendrocytes. Journal of visualized experiments : JoVE. issue 135. 2018-08-06. PMID:29863670. |
the efficient and robust isolation and culture of primary oligodendrocytes (ols) is a valuable tool for the in vitro study of the development of oligodendroglia as well as the biology of demyelinating diseases such as multiple sclerosis and pelizaeus-merzbacher-like disease (pmld). |
2018-08-06 |
2023-08-13 |
mouse |
| Miho Hashimoto, Shinji Yamamoto, Kensuke Iwasa, Kota Yamashina, Masaki Ishikawa, Kei Maruyama, Francesca Bosetti, Keisuke Yoshikaw. The flavonoid Baicalein attenuates cuprizone-induced demyelination via suppression of neuroinflammation. Brain research bulletin. vol 135. 2018-07-05. PMID:28923306. |
multiple sclerosis (ms) is a chronic demyelinating disease of the central nervous system characterized by recurrent and progressive demyelination/remyelination cycles, neuroinflammation, oligodendrocyte loss, and axonal pathology. |
2018-07-05 |
2023-08-13 |
mouse |
| B M Escribano, E Luque, M Aguilar-Luque, M Feijóo, J Caballero-Villarraso, L A Torres, V Ramirez, F I García-Maceira, E Agüera, A Santamaria, I Túne. Dose-dependent S-allyl cysteine ameliorates multiple sclerosis disease-related pathology by reducing oxidative stress and biomarkers of dysbiosis in experimental autoimmune encephalomyelitis. European journal of pharmacology. vol 815. 2018-07-05. PMID:28939293. |
experimental autoimmune encephalomyelitis (eae) as a model of multiple sclerosis (ms) was induced by the myelin oligodendrocyte glycoprotein (mog), whose effects were quantified by examining the changes in: clinical score, lipid peroxidation products, carbonylated proteins, glutathione system, tumor necrosis factor alpha (tnfα), and lipopolysaccharide membrane bacteria (lps). |
2018-07-05 |
2023-08-13 |
Not clear |
| Vijayaraghava T S Rao, Damla Khan, Russell G Jones, Diane S Nakamura, Timothy E Kennedy, Qiao-Ling Cui, Malena B Rone, Luke M Healy, Richard Watson, Supurna Ghosh, Jack P Ante. Potential Benefit of the Charge-Stabilized Nanostructure Saline RNS60 for Myelin Maintenance and Repair. Scientific reports. vol 6. 2018-05-22. PMID:27451946. |
myelin injury in multiple sclerosis (ms) has been attributed both to "outside-in" primary immune mediated and "inside-out" metabolic stress of oligodendrocyte (ol) related mechanisms. |
2018-05-22 |
2023-08-13 |
rat |
| Roobina Boghozian, Brienne A McKenzie, Leina B Saito, Ninad Mehta, William G Branton, JianQiang Lu, Glen B Baker, Farshid Noorbakhsh, Christopher Powe. Suppressed oligodendrocyte steroidogenesis in multiple sclerosis: Implications for regulation of neuroinflammation. Glia. vol 65. issue 10. 2018-05-02. PMID:28707358. |
suppressed oligodendrocyte steroidogenesis in multiple sclerosis: implications for regulation of neuroinflammation. |
2018-05-02 |
2023-08-13 |
human |
| Suyog U Pol, Jessie J Polanco, Richard A Seidman, Melanie A O'Bara, Hani J Shayya, Karen C Dietz, Fraser J Si. Network-Based Genomic Analysis of Human Oligodendrocyte Progenitor Differentiation. Stem cell reports. vol 9. issue 2. 2018-04-23. PMID:28793249. |
impaired human oligodendrocyte progenitor cell (hopc) differentiation likely contributes to failed remyelination in multiple sclerosis. |
2018-04-23 |
2023-08-13 |
human |