| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fucheng Luo, Zhen Zhang, Yu Lu. Differential Role of p53 in Oligodendrocyte Survival in Response to Various Stresses: Experimental Autoimmune Encephalomyelitis, Cuprizone Intoxication or White Matter Stroke. International journal of molecular sciences. vol 22. issue 23. 2021-12-10. PMID:34884611. |
promoting oligodendrocyte viability has been proposed as a therapeutic strategy for alleviating many neuronal diseases, such as multiple sclerosis and stroke. |
2021-12-10 |
2023-08-13 |
mouse |
| Prashant Sadanandan, Natalie L Payne, Guizhi Sun, Anusha Ashokan, Siddaramana G Gowd, Arsha Lal, Madathiparambil Kumaran Satheesh Kumar, Sreeranjini Pulakkat, Shantikumar V Nair, Krishnakumar N Menon, Claude C A Bernard, Manzoor Koyakutt. Exploiting the preferential phagocytic uptake of nanoparticle-antigen conjugates for the effective treatment of autoimmunity. Nanomedicine : nanotechnology, biology, and medicine. vol 40. 2021-12-09. PMID:34748963. |
the brain autoantigen, myelin oligodendrocyte glycoprotein (mog), was conjugated to 200 or 500 nm silica nanoparticles (snp) and delivered to the spleen and liver-resident macrophages of experimental autoimmune encephalomyelitis (eae) mice, used as a model of multiple sclerosis. |
2021-12-09 |
2023-08-13 |
mouse |
| Mark A Petersen, Reshmi Tognatta, Anke Meyer-Franke, Eric A Bushong, Andrew S Mendiola, Zhaoqi Yan, Abinaya Muthusamy, Mario Merlini, Rosa Meza-Acevedo, Belinda Cabriga, Yungui Zhou, Reuben Thomas, Jae Kyu Ryu, Hans Lassmann, Mark H Ellisman, Katerina Akassoglo. BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis. Brain : a journal of neurology. vol 144. issue 8. 2021-12-08. PMID:34426831. |
by integrating in vivo two-photon imaging co-registered with electron microscopy and transcriptomics in chronic neuroinflammatory lesions, we found that oligodendrocyte precursor cells clustered perivascularly at sites of limited remyelination with deposition of fibrinogen, a blood coagulation factor abundantly deposited in multiple sclerosis lesions. |
2021-12-08 |
2023-08-13 |
Not clear |
| Karin Mausner-Fainberg, Moshe Benhamou, Maya Golan, Nadav Bleich Kimelman, Uri Danon, Ehud Marom, Arnon Karn. Specific Blockade of Bone Morphogenetic Protein-2/4 Induces Oligodendrogenesis and Remyelination in Demyelinating Disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 18. issue 3. 2021-12-04. PMID:34159538. |
oligodendrocyte precursor cells (opcs) are present in demyelinated lesions of multiple sclerosis (ms) patients. |
2021-12-04 |
2023-08-13 |
mouse |
| Bo Chen, Meng-Cui Gui, Su-Qiong Ji, Yi Xie, Dai-Shi Tian, Bi-Tao B. Distinct Immunological Features of Inflammatory Demyelinating Diseases of the Central Nervous System. Neuroimmunomodulation. 2021-11-25. PMID:34823248. |
the immunological features between neuromyelitis optica spectrum disorder (nmosd), multiple sclerosis (ms), and myelin oligodendrocyte glycoprotein antibody-associated disease (mogad), lacked systemic comparisons. |
2021-11-25 |
2023-08-13 |
Not clear |
| Timucin Avşar, Gökçe Çelikyapi Erdem, Gökhan Terzioğlu, Eda Tahir Turanl. Investigation of neuro-inflammatory parameters in a cuprizone induced mouse model of multiple sclerosis. Turkish journal of biology = Turk biyoloji dergisi. vol 45. issue 5. 2021-11-23. PMID:34803461. |
cuprizone, copper chelator, treatment of mouse is a toxic model of multiple sclerosis (ms) in which oligodendrocyte death, demyelination and remyelination can be observed. |
2021-11-23 |
2023-08-13 |
mouse |
| Uddalak Chakraborty, Shrestha Ghosh, Amlan Kusum Datta, Atanu Chandr. Recurrent ataxia and dysarthria in myelin oligodendrocyte glycoprotein antibody-associated disorder. BMJ case reports. vol 14. issue 11. 2021-11-16. PMID:34772679. |
however, introduction of several new biomarkers such as aquaporin-4 igg and myelin oligodendrocyte glycoprotein igg has made distinction between diseases such as multiple sclerosis and myelin oligodendrocyte glycoprotein antibody-associated disorder easier. |
2021-11-16 |
2023-08-13 |
Not clear |
| Inderjit Singh, Judong Kim, Nishant Saxena, Seungho Choi, S M Touhidul Islam, Avtar K Singh, Mushfiquddin Khan, Jeseong Wo. Vascular and immunopathological role of Asymmetric Dimethylarginine (ADMA) in Experimental Autoimmune Encephalomyelitis. Immunology. vol 164. issue 3. 2021-11-12. PMID:34310708. |
patients with multiple sclerosis (ms) are reported to have elevated blood levels of adma, and mice with experimental autoimmune encephalomyelitis (eae, an animal model of ms) generated by auto-immunization of myelin oligodendrocyte glycoprotein (mog) and blood-brain barrier (bbb) disruption by pertussis toxin also had increased blood adma levels in parallel with induction of clinical disease. |
2021-11-12 |
2023-08-13 |
mouse |
| Genaro Gabriel Ortiz, Mario A Mireles-Ramírez, Fermín P Pacheco-Moisés, Luis J Ramírez-Jirano, Oscar K Bitzer-Quintero, Daniela L C Delgado-Lara, L Javier Flores-Alvarado, Miriam A Mora-Navarro, Miguel Huerta, Blanca M G Torres-Mendoz. Are electrophysiological and oligodendrocyte alterations an element in the development of multiple sclerosis at the same time as or before the immune response? The International journal of neuroscience. vol 131. issue 12. 2021-11-10. PMID:32571126. |
are electrophysiological and oligodendrocyte alterations an element in the development of multiple sclerosis at the same time as or before the immune response? |
2021-11-10 |
2023-08-13 |
Not clear |
| Laura Clarke, Simon Arnett, Kate Lilley, Jacky Liao, Sandeep Bhuta, Simon A Broadle. Magnetic resonance imaging in neuromyelitis optica spectrum disorder. Clinical and experimental immunology. vol 206. issue 3. 2021-11-09. PMID:34080180. |
neuromyelitis optica spectrum disorder (nmosd) is an inflammatory disease of the central nervous system (cns) associated with antibodies to aquaporin-4 (aqp4), which has distinct clinical, radiological and pathological features, but also has some overlap with multiple sclerosis and myelin oligodendrocyte glycoprotein (mog) antibody associated disease. |
2021-11-09 |
2023-08-13 |
Not clear |
| Frederik Bartels, Angelo Lu, Frederike Cosima Oertel, Carsten Finke, Friedemann Paul, Claudia Chie. Clinical and neuroimaging findings in MOGAD-MRI and OCT. Clinical and experimental immunology. vol 206. issue 3. 2021-11-09. PMID:34152000. |
clinical and neuroimaging findings in mogad-mri and oct. myelin oligodendrocyte glycoprotein antibody-associated disorders (mogad) are rare in both children and adults, and have been recently suggested to be an autoimmune neuroinflammatory group of disorders that are different from aquaporin-4 autoantibody-associated neuromyelitis optica spectrum disorder and from classic multiple sclerosis. |
2021-11-09 |
2023-08-13 |
Not clear |
| Assia Tiane, Melissa Schepers, Renzo Riemens, Ben Rombaut, Patrick Vandormael, Veerle Somers, Jos Prickaerts, Niels Hellings, Daniel van den Hove, Tim Vanmierl. DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation. Cellular and molecular life sciences : CMLS. vol 78. issue 19-20. 2021-11-08. PMID:34482420. |
the differentiation of oligodendrocyte precursor cells (opcs) into myelinating oligodendrocytes is the prerequisite for remyelination in demyelinated disorders such as multiple sclerosis (ms). |
2021-11-08 |
2023-08-13 |
human |
| An Cheng, Wenbin Jia, Ichiro Kawahata, Kohji Fukunag. A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models. EBioMedicine. vol 72. 2021-11-01. PMID:34624687. |
a novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models. |
2021-11-01 |
2023-08-13 |
mouse |
| Moon Hee Hu. Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: Presentation, Diagnosis, and Management. Pediatric annals. vol 50. issue 6. 2021-10-27. PMID:34115560. |
when myelin oligodendrocyte glycoprotein (mog) antibodies were first discovered, they were thought to be a biomarker for multiple sclerosis (ms). |
2021-10-27 |
2023-08-13 |
Not clear |
| Tetsuya Akaishi, Noriko Himori, Takayuki Takeshita, Tatsuro Misu, Toshiyuki Takahashi, Yoshiki Takai, Shuhei Nishiyama, Juichi Fujimori, Tadashi Ishii, Masashi Aoki, Kazuo Fujihara, Toru Nakazawa, Ichiro Nakashim. Five-year visual outcomes after optic neuritis in anti-MOG antibody-associated disease. Multiple sclerosis and related disorders. vol 56. 2021-10-26. PMID:34461572. |
optic neuritis (on) is a major phenotype of clinical attack related to demyelinating neurological diseases of the central nervous system, including multiple sclerosis (ms), anti-aquaporin-4 (aqp4) antibody-positive neuromyelitis optica spectrum disorder (nmosd), and anti-myelin oligodendrocyte glycoprotein antibody-associated disease (mogad). |
2021-10-26 |
2023-08-13 |
Not clear |
| Anna Presicci, Maria Serra, Mariaclara Achille, Elvita Caputo, Lucia Margar. Pediatric Optic Neuritis: Description of Four Cases and Review of the Literature. Children (Basel, Switzerland). vol 8. issue 10. 2021-10-26. PMID:34682120. |
pon has a high impact on the quality of life as it may or may not evolve into other acquired demyelinating syndromes (adss), such as multiple sclerosis (ms), neuromyelitis optica (nmo), or other syndromes related to the myelin oligodendrocyte glycoprotein igg antibodies (mog-igg). |
2021-10-26 |
2023-08-13 |
Not clear |
| Jianqin Niu, Guangdan Yu, Xiaorui Wang, Wenlong Xia, Yuxin Wang, Kimberly K Hoi, Feng Mei, Lan Xiao, Jonah R Chan, Stephen P J Fanc. Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturation. Neuron. vol 109. issue 19. 2021-10-25. PMID:34390652. |
oligodendrocyte (ol) maturation arrest in human white matter injury contributes significantly to the failure of endogenous remyelination in multiple sclerosis (ms) and newborn brain injuries such as hypoxic ischemic encephalopathy (hie) that cause cerebral palsy. |
2021-10-25 |
2023-08-13 |
human |
| Yang Zheng, Meng-Ting Cai, Er-Chuang Li, Wei Fang, Chun-Hong Shen, Yin-Xi Zhan. Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disorder Masquerading as Multiple Sclerosis: An Under-Recognized Entity? Frontiers in immunology. vol 12. 2021-10-18. PMID:34220818. |
case report: myelin oligodendrocyte glycoprotein antibody-associated disorder masquerading as multiple sclerosis: an under-recognized entity? |
2021-10-18 |
2023-08-13 |
Not clear |
| Negar Molazadeh, Angeliki G Filippatou, Eleni S Vasileiou, Michael Levy, Elias S Sotircho. Evidence for and against subclinical disease activity and progressive disease in MOG antibody disease and neuromyelitis optica spectrum disorder. Journal of neuroimmunology. vol 360. 2021-10-11. PMID:34547512. |
myelin oligodendrocyte glycoprotein antibody disease (mogad) and aquaporin-4 igg seropositive neuromyelitis optica spectrum disorder (aqp4-igg+ nmosd) are generally considered to be relapsing disorders, without clinical progression or subclinical disease activity outside of clinical relapses, in contrast to multiple sclerosis (ms). |
2021-10-11 |
2023-08-13 |
Not clear |
| Elia Sechi, Karl N Krecke, Steven A Messina, Marina Buciuc, Sean J Pittock, John J Chen, Brian G Weinshenker, A Sebastian Lopez-Chiriboga, Claudia F Lucchinetti, Nicholas L Zalewski, Jan Mendelt Tillema, Amy Kunchok, Salvatore Monaco, Padraig P Morris, James P Fryer, Adam Nguyen, Tammy Greenwood, Stephanie B Syc-Mazurek, B Mark Keegan, Eoin P Flanaga. Comparison of MRI Lesion Evolution in Different Central Nervous System Demyelinating Disorders. Neurology. vol 97. issue 11. 2021-10-05. PMID:34261784. |
we sought to compare mri t2 lesion evolution in myelin oligodendrocyte glycoprotein immunoglobulin g (igg)-associated disorder (mogad), aquaporin 4 igg-positive neuromyelitis optica spectrum disorder (aqp4-igg-nmosd), and multiple sclerosis (ms). |
2021-10-05 |
2023-08-13 |
Not clear |