| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Florian Pernin, Julia Luo, Qiao-Ling Cui, Manon Blain, Milton G F Fernandes, Moein Yaqubi, Myriam Srour, Jeff Hall, Roy Dudley, Hélène Jamann, Catherine Larochelle, Stephanie E J Zandee, Alexandre Prat, Jo Anne Stratton, Timothy E Kennedy, Jack P Ante. Diverse injury responses of human oligodendrocyte to mediators implicated in multiple sclerosis. Brain : a journal of neurology. 2022-02-24. PMID:35202462. |
early multiple sclerosis lesions feature relative preservation of oligodendrocyte cell bodies with dying back retraction of their myelinating processes. |
2022-02-24 |
2023-08-13 |
human |
| Tracy L Fabri, Julia O'Mahony, Giulia Fadda, Raquel E Gur, Ruben C Gur, E Ann Yeh, Brenda L Banwell, Christine Til. Cognitive function in pediatric-onset relapsing myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). Multiple sclerosis and related disorders. vol 59. 2022-02-20. PMID:35183817. |
little is known about the cognitive sequelae of relapsing myelin oligodendrocyte glycoprotein antibody-associated disease (mogad) with onset in childhood or adolescence.overall, adults had 41% more risk than children to relapse over the whole disease course overall, adults had 41% more risk than children to relapse over the whole disease course objective: to compare cognitive performance in participants with pediatric-onset relapsing mogad, pediatric-onset multiple sclerosis (poms), and age-matched healthy controls. |
2022-02-20 |
2023-08-13 |
human |
| Katharina Messias, Vanessa Daccach Marques, Andre Messia. Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis: an update. Arquivos brasileiros de oftalmologia. 2022-02-16. PMID:35170658. |
another important differential diagnosis of myelin oligodendrocyte glycoprotein-igg--associated optic neuritis is multiple sclerosis. |
2022-02-16 |
2023-08-13 |
Not clear |
| Meltem Yıldız Kayaoğlu, Gözde Girgin, Ismail Solmaz, Terken Baydar, Banu Anla. Urine neopterin in childhood acute demyelinating diseases: Potential for differential diagnosis. Multiple sclerosis and related disorders. vol 59. 2022-02-12. PMID:35149394. |
inflammatory demyelinating diseases of the central nervous system (cns) in childhood include clinically and radiologically defined diseases such as acute disseminated encephalomyelitis (adem), multiple sclerosis (ms), neuromyelitis optica spectrum disorder (nmosd), and myelin oligodendrocyte glycoprotein antibody-associated disorder (mogad). |
2022-02-12 |
2023-08-13 |
Not clear |
| Ju Liu, Xiaoyan Yang, Jiali Pan, Zhihua Wei, Peidong Liu, Min Chen, Hongbo Li. Single-Cell Transcriptome Profiling Unravels Distinct Peripheral Blood Immune Cell Signatures of RRMS and MOG Antibody-Associated Disease. Frontiers in neurology. vol 12. 2022-01-31. PMID:35095746. |
relapsing-remitting multiple sclerosis (rrms) and myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad) are inflammatory demyelinating diseases of the central nervous system (cns). |
2022-01-31 |
2023-08-13 |
human |
| Mandy Meijer, Eneritz Agirre, Mukund Kabbe, Cassandra A van Tuijn, Abeer Heskol, Chao Zheng, Ana Mendanha Falcão, Marek Bartosovic, Leslie Kirby, Daniela Calini, Michael R Johnson, M Ryan Corces, Thomas J Montine, Xingqi Chen, Howard Y Chang, Dheeraj Malhotra, Gonçalo Castelo-Branc. Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility. Neuron. 2022-01-30. PMID:35093191. |
epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility. |
2022-01-30 |
2023-08-13 |
mouse |
| Mandy Meijer, Eneritz Agirre, Mukund Kabbe, Cassandra A van Tuijn, Abeer Heskol, Chao Zheng, Ana Mendanha Falcão, Marek Bartosovic, Leslie Kirby, Daniela Calini, Michael R Johnson, M Ryan Corces, Thomas J Montine, Xingqi Chen, Howard Y Chang, Dheeraj Malhotra, Gonçalo Castelo-Branc. Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility. Neuron. 2022-01-30. PMID:35093191. |
multiple sclerosis (ms) is characterized by a targeted attack on oligodendroglia (olg) and myelin by immune cells, which are thought to be the main drivers of ms susceptibility. |
2022-01-30 |
2023-08-13 |
mouse |
| B Rodríguez-Acevedo, A Rovira, A Vidal-Jordana, D Moncho, D Pareto, J Sastre-Garrig. [Optic neuritis: aetiopathogenesis, diagnosis, prognosis and management]. Revista de neurologia. vol 74. issue 3. 2022-01-27. PMID:35084734. |
the main causes of optic neuritis (on) are multiple sclerosis (ms), neuromyelitis optica spectrum disorder (nmosd) and myelin oligodendrocyte glycoprotein antibody disease, also known as mogad. |
2022-01-27 |
2023-08-13 |
Not clear |
| Gaurav Nepal, Sanjeev Kharel, Megan Ariel Coghlan, Parash Rayamajhi, Rajeev Ojh. Safety and efficacy of rituximab for relapse prevention in myelin oligodendrocyte glycoprotein immunoglobulin G (MOG-IgG)-associated disorders (MOGAD): A systematic review and meta-analysis. Journal of neuroimmunology. vol 364. 2022-01-22. PMID:35063726. |
myelin oligodendrocyte glycoprotein immunoglobulin g (mog-igg)-associated disorders (mogad) is neuroimmunological disorder manifesting as episodes of adem, optic neuritis, transverse myelitis, brainstem encephalitis, and other cns manifestations and notably, distinct from multiple sclerosis (ms) and neuromyelitis optica spectrum disorders (nmosd). |
2022-01-22 |
2023-08-13 |
Not clear |
| Valerio Castoldi, Silvia Marenna, Su-Chun Huang, Raffaele d'Isa, Linda Chaabane, Giancarlo Comi, Letizia Leocan. Dose-dependent effect of myelin oligodendrocyte glycoprotein on visual function and optic nerve damage in experimental autoimmune encephalomyelitis. Journal of neuroscience research. 2022-01-19. PMID:35043454. |
female dark agouti rats were immunized with increasing doses of myelin oligodendrocyte glycoprotein (mog) to develop experimental autoimmune encephalomyelitis (eae), a preclinical model of multiple sclerosis. |
2022-01-19 |
2023-08-13 |
rat |
| Stephanie Barnes, Yuyi You, Ting Shen, Todd A Hardy, Clare Fraser, Stephen W Reddel, Fabienne Brilot, Sudarshini Ramanathan, Alexandr Klistorner, Con Yiannika. Structural and functional markers of optic nerve damage in myelin oligodendrocyte glycoprotein antibody-associated optic neuritis. Multiple sclerosis journal - experimental, translational and clinical. vol 7. issue 4. 2022-01-17. PMID:35035987. |
optic neuritis (on) occurs in immune-mediated disorders including multiple sclerosis (ms), aquaporin-4 antibody-positive (aqp4) neuromyelitis optica spectrum disorder (aqp4-nmosd) and myelin oligodendrocyte glycoprotein (mog) antibody-associated demyelination (mogad). |
2022-01-17 |
2023-08-13 |
Not clear |
| John J Chen, Elias S Sotirchos, Amanda D Henderson, Eleni S Vasileiou, Eoin P Flanagan, M Tariq Bhatti, Sepideh Jamali, Eric R Eggenberger, Marie Dinome, Larry P Frohman, Anthony C Arnold, Laura Bonelli, Nicolas Seleme, Alvaro J Mejia-Vergara, Heather E Moss, Tanyatuth Padungkiatsagul, Hadas Stiebel-Kalish, Itay Lotan, Mark A Hellmann, Dave Hodge, Frederike Cosima Oertel, Friedemann Paul, Shiv Saidha, Peter A Calabresi, Sean J Pittoc. OCT retinal nerve fiber layer thickness differentiates acute optic neuritis from MOG antibody-associated disease and Multiple Sclerosis: RNFL thickening in acute optic neuritis from MOGAD vs MS. Multiple sclerosis and related disorders. vol 58. 2022-01-17. PMID:35038647. |
optic neuritis (on) is the most common manifestation of myelin oligodendrocyte glycoprotein antibody associated disorder (mogad) and multiple sclerosis (ms). |
2022-01-17 |
2023-08-13 |
Not clear |
| Jana Remlinger, Adrian Madarasz, Kirsten Guse, Robert Hoepner, Maud Bagnoud, Ivo Meli, Moritz Feil, Mathias Abegg, Christopher Linington, Anthony Shock, Babak Boroojerdi, Peter Kiessling, Bryan Smith, Volker Enzmann, Andrew Chan, Anke Salme. Antineonatal Fc Receptor Antibody Treatment Ameliorates MOG-IgG-Associated Experimental Autoimmune Encephalomyelitis. Neurology(R) neuroimmunology & neuroinflammation. vol 9. issue 2. 2022-01-14. PMID:35027475. |
myelin oligodendrocyte glycoprotein antibody-associated disorder (mogad) is a rare, autoimmune demyelinating cns disorder, distinct from multiple sclerosis and neuromyelitis optica spectrum disorder. |
2022-01-14 |
2023-08-13 |
Not clear |
| Wonjin Yun, Kyung-Ah Choi, Insik Hwang, Jie Zheng, Minji Park, Wonjun Hong, Ah-Young Jang, Jeong Hee Kim, Wonji Choi, Dae-Sung Kim, In Yong Kim, Yong Jun Kim, Ying Liu, Byung Sun Yoon, Gyuman Park, Gwonhwa Song, Sunghoi Hong, Seungkwon Yo. OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease. NPJ Regenerative medicine. vol 7. issue 1. 2022-01-14. PMID:35027563. |
the generation of human oligodendrocyte progenitor cells (opcs) may be therapeutically valuable for human demyelinating diseases such as multiple sclerosis. |
2022-01-14 |
2023-08-13 |
human |
| Meric A Altinoz, Sinan Guloksuz, Aysel Ozpina. Immunomodifying and neuroprotective effects of noscapine: Implications for multiple sclerosis, neurodegenerative, and psychiatric disorders. Chemico-biological interactions. 2021-12-29. PMID:34963564. |
noscapine protects oligodendroglia from ischemic and chemical injury, binds to bitter taste receptors, antagonizes the bradykinin and histaminergic systems, which may be of benefit in treatment of multiple sclerosis. |
2021-12-29 |
2023-08-13 |
rat |
| Rina Aharoni, Raya Eilam, Shaul Lerner, Efrat Shavit-Stein, Amir Dori, Joab Chapman, Ruth Arno. Neuroprotective Effect of Glatiramer Acetate on Neurofilament Light Chain Leakage and Glutamate Excess in an Animal Model of Multiple Sclerosis. International journal of molecular sciences. vol 22. issue 24. 2021-12-24. PMID:34948217. |
axonal and neuronal pathologies are a central constituent of multiple sclerosis (ms) and its animal model, experimental autoimmune encephalomyelitis (eae), induced by the myelin oligodendrocyte glycoprotein (mog) 35-55 peptide. |
2021-12-24 |
2023-08-13 |
mouse |
| Keivan Nedaei, Mahdi Hesaraki, Saeideh Mazloomzadeh, Mehdi Totonchi, Ali Reza Biglar. Lentiviral Mediated Expression of Soluble Neuropilin 1 Inhibits Semaphorin 3A-mediated Collapse Activity Basic and clinical neuroscience. vol 12. issue 2. 2021-12-20. PMID:34925719. |
in multiple sclerosis (ms), sema 3a expression increases and inhibits oligodendrocyte precursor cell differentiation. |
2021-12-20 |
2023-08-13 |
Not clear |
| Samantha Epstein, Zongqi Xia, Annie J Lee, Megan Dahl, Keith Edwards, Elle Levit, Erin E Longbrake, Christopher Perrone, Katelyn Kavak, Bianca Weinstock-Guttman, Fatoumata Diallo, Adelle Ricci, Claire S Riley, Philip L De Jager, Rebecca Farber, Sarah F Wesle. Vaccination Against SARS-CoV-2 in Neuroinflammatory Disease: Early Safety/Tolerability Data. Multiple sclerosis and related disorders. vol 57. 2021-12-19. PMID:34923427. |
this has led to significant vaccine hesitancy in patients with neuroinflammatory diseases (nid); including, but not limited to: multiple sclerosis (ms), neuromyelitis optica spectrum disorders (nmosd), neurosarcoidosis and myelin oligodendrocyte antibody-mediated disease (mog-ad). |
2021-12-19 |
2023-08-13 |
Not clear |
| Niklas Huntemann, Anna Vogelsang, Linda Groeneweg, Alice Willison, Alexander M Herrmann, Sven G Meuth, Susann Eichle. An optimized and validated protocol for inducingchronic experimental autoimmune encephalomyelitis in C57BL/6J mice. Journal of neuroscience methods. 2021-12-17. PMID:34920025. |
myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis (eae) is the most commonly used animal model of multiple sclerosis. |
2021-12-17 |
2023-08-13 |
mouse |
| Zixuan Gao, Chu Zhang, Zhaowei Feng, Ziqi Liu, Yaru Yang, Kexin Yang, Lei Chen, Ruiqin Ya. C1q inhibits differentiation of oligodendrocyte progenitor cells via Wnt/β-catenin signaling activation in a cuprizone-induced mouse model of multiple sclerosis. Experimental neurology. 2021-12-13. PMID:34902359. |
c1q inhibits differentiation of oligodendrocyte progenitor cells via wnt/β-catenin signaling activation in a cuprizone-induced mouse model of multiple sclerosis. |
2021-12-13 |
2023-08-13 |
mouse |