| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Serretti, P N Malitas, L Mandelli, C Lorenzi, C Ploia, B Alevizos, C Nikolaou, F Boufidou, G N Christodoulou, E Smerald. Further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders. The pharmacogenomics journal. vol 4. issue 4. 2005-03-07. PMID:15111989. |
further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders. |
2005-03-07 |
2023-08-12 |
human |
| A Serretti, P N Malitas, L Mandelli, C Lorenzi, C Ploia, B Alevizos, C Nikolaou, F Boufidou, G N Christodoulou, E Smerald. Further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders. The pharmacogenomics journal. vol 4. issue 4. 2005-03-07. PMID:15111989. |
we previously reported an association between the functional polymorphism in the upstream regulatory region of the serotonin transporter gene (sertpr) and the prophylactic efficacy of lithium in a sample of 201 italian subjects affected by mood disorders. |
2005-03-07 |
2023-08-12 |
human |
| Yung-Yu Huang, Cristina Battistuzzi, Maria A Oquendo, Jill Harkavy-Friedman, Laurence Greenhill, Gil Zalsman, Beth Brodsky, Victoria Arango, David A Brent, J John Man. Human 5-HT1A receptor C(-1019)G polymorphism and psychopathology. The international journal of neuropsychopharmacology. vol 7. issue 4. 2005-02-24. PMID:15469667. |
dysfunction of the serotonin (5-ht1a) receptor (5-htr1a) has been implicated in mood disorders, anxiety disorders, psychosis and the action of antidepressants. |
2005-02-24 |
2023-08-12 |
human |
| Vadim D Khait, Yung-yu Huang, Gil Zalsman, Maria A Oquendo, David A Brent, Jill M Harkavy-Friedman, J John Man. Association of serotonin 5-HT2A receptor binding and the T102C polymorphism in depressed and healthy Caucasian subjects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 1. 2005-01-26. PMID:15483560. |
serotonin 5-ht2a receptor (5-ht2a) binding is reported to be altered in individuals with suicidal behavior, mood disorders, and aggressive-impulsive traits. |
2005-01-26 |
2023-08-12 |
human |
| Demet Akin, D Hal Manier, Elaine Sanders-Bush, Richard C Shelto. Decreased serotonin 5-HT2A receptor-stimulated phosphoinositide signaling in fibroblasts from melancholic depressed patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 11. 2005-01-11. PMID:15187984. |
abnormalities in serotonin (5-ht) receptors and 5-ht receptor-mediated signal transduction systems have been widely reported in mood disorders. |
2005-01-11 |
2023-08-12 |
Not clear |
| Masafumi Kodama, Takashi Fujioka, Ronald S Duma. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat. Biological psychiatry. vol 56. issue 8. 2005-01-10. PMID:15476686. |
there has been increasing evidence that atypical antipsychotics are effective in the treatment of mood disorders or for augmenting 5-hydroxytryptamine selective reuptake inhibitors for treatment-resistant depression. |
2005-01-10 |
2023-08-12 |
rat |
| Alex Malinin, Benjamin Oshrine, Victor Serebruan. Treatment with selective serotonin reuptake inhibitors for enhancing wound healing. Medical hypotheses. vol 63. issue 1. 2005-01-06. PMID:15193359. |
selective serotonin reuptake inhibitors (ssris) are well-established medications for the treatment of mood disorders including major depression. |
2005-01-06 |
2023-08-12 |
Not clear |
| Alessandro Serretti, Paola Artiol. From molecular biology to pharmacogenetics: a review of the literature on antidepressant treatment and suggestions of possible candidate genes. Psychopharmacology. vol 174. issue 4. 2004-12-02. PMID:14997279. |
pharmacogenetic studies in mood disorders are raising increasing interest, after the first findings of a significant association between antidepressant response and a functional polymorphism in the upstream regulatory region of the serotonin transporter gene (sertpr). |
2004-12-02 |
2023-08-12 |
Not clear |
| Maartje M L de Win, Liesbeth Reneman, Johannes B Reitsma, Gerard J den Heeten, Jan Booij, Wim van den Brin. Mood disorders and serotonin transporter density in ecstasy users--the influence of long-term abstention, dose, and gender. Psychopharmacology. vol 173. issue 3-4. 2004-11-22. PMID:14726997. |
mood disorders and serotonin transporter density in ecstasy users--the influence of long-term abstention, dose, and gender. |
2004-11-22 |
2023-08-12 |
Not clear |
| Timo Heinrich, Henning Böttcher, Gerd D Bartoszyk, Hartmut E Greiner, Christoph A Seyfried, Christoph Van Amsterda. Indolebutylamines as selective 5-HT(1A) agonists. Journal of medicinal chemistry. vol 47. issue 19. 2004-10-07. PMID:15341483. |
a series of new 1-[4-(indol-3-yl)butyl]-4-arylpiperazines was prepared to identify highly selective and potent 5-ht(1a) agonists as potential pharmacological tools in studies of mood disorders. |
2004-10-07 |
2023-08-12 |
Not clear |
| Andrew H Kemp, Marcus A Gray, Richard B Silberstein, Stuart M Armstrong, Pradeep J Natha. Augmentation of serotonin enhances pleasant and suppresses unpleasant cortical electrophysiological responses to visual emotional stimuli in humans. NeuroImage. vol 22. issue 3. 2004-09-16. PMID:15219580. |
the serotonergic system is one of the major systems targeted in the pharmacological treatment of a wide range of mood disorders including depression; however, little is known about the neurophysiological mechanisms underlying the effects of serotonin (5-ht) on affective phenomena including emotional behaviours, mood and emotional processing. |
2004-09-16 |
2023-08-12 |
human |
| Ming T Tsuang, Levi Taylor, Stephen V Faraon. An overview of the genetics of psychotic mood disorders. Journal of psychiatric research. vol 38. issue 1. 2004-08-31. PMID:14690766. |
linkage studies of mood disorders in general have also provided some support for that notion, as have associated studies involving serotonin and dopamine genes and psychotic mood disorder. |
2004-08-31 |
2023-08-12 |
Not clear |
| A LLerena, R Berecz, P Dorado, A P González, E M Peñas-LLedó, A De La Rubi. CYP2C9 gene and susceptibility to major depressive disorder. The pharmacogenomics journal. vol 3. issue 5. 2004-06-29. PMID:14583800. |
alteration of monoaminergic neurotransmission has been implicated in the pathophysiology of mood disorders, and cyp2c9 enzyme activity has been shown to be modulated by serotonin in vitro. |
2004-06-29 |
2023-08-12 |
human |
| Zhuo Chen, Kate Waimey, Louis D Van de Kar, Gonzalo A Carrasco, Michelle Landry, George Battagli. Prenatal cocaine exposure potentiates paroxetine-induced desensitization of 5-HT2A receptor function in adult male rat offspring. Neuropharmacology. vol 46. issue 7. 2004-06-29. PMID:15081791. |
these data, demonstrating that prenatal exposure to cocaine potentiates paroxetine-induced desensitization of 5-ht(2a) receptor function, may be clinically relevant with respect to treating mood disorders in adults exposed in utero to cocaine. |
2004-06-29 |
2023-08-12 |
rat |
| Ghanshyam N Pandey, Subhash C Pandey, Xinguo Ren, Yogesh Dwivedi, Philip G Janica. Serotonin receptors in platelets of bipolar and schizoaffective patients: effect of lithium treatment. Psychopharmacology. vol 170. issue 2. 2004-04-12. PMID:12845409. |
abnormalities of serotonin (5ht) function have been implicated in mood disorders, and lithium treatment may produce its beneficial effects by modifying serotonergic mechanisms. |
2004-04-12 |
2023-08-12 |
Not clear |
| Antonio L López-Figueroa, Camille S Norton, Manuel O López-Figueroa, Denise Armellini-Dodel, Sharon Burke, Huda Akil, Juan F López, Stanley J Watso. Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia. Biological psychiatry. vol 55. issue 3. 2004-04-01. PMID:14744462. |
alterations of serotonin neurotransmission are implicated in both mood disorders and schizophrenia. |
2004-04-01 |
2023-08-12 |
human |
| Hanna Ostlund, Eva Keller, Yasmin L Hur. Estrogen receptor gene expression in relation to neuropsychiatric disorders. Annals of the New York Academy of Sciences. vol 1007. 2004-03-25. PMID:14993040. |
the norepinephrine (ne) system is, similar to serotonin, a target for antidepressant drugs, and projects to mesocorticolimbic structures implicated in mood disorders. |
2004-03-25 |
2023-08-12 |
human |
| Sylvie Lemonde, Anastasia Rogaeva, Paul R Alber. Cell type-dependent recruitment of trichostatin A-sensitive repression of the human 5-HT1A receptor gene. Journal of neurochemistry. vol 88. issue 4. 2004-03-15. PMID:14756806. |
regulation of serotonin (5-ht)1a receptor expression in brain is implicated in mood disorders such as depression and anxiety. |
2004-03-15 |
2023-08-12 |
human |
| D N D'Souza, Y Zhang, F Garcia, G Battaglia, L D Van de Ka. Fluoxetine-induced changes in body weight and 5-HT1A receptor-mediated hormone secretion in rats on a tryptophan-deficient diet. American journal of physiology. Regulatory, integrative and comparative physiology. vol 286. issue 2. 2004-02-27. PMID:14604841. |
tryptophan depleting protocols are commonly used to study the role of serotonin in mood disorders. |
2004-02-27 |
2023-08-12 |
rat |
| Kimberly A Yonker. Paroxetine treatment of mood disorders in women: premenstrual dysphoric disorder and hot flashes. Psychopharmacology bulletin. vol 37 Suppl 1. 2004-01-28. PMID:14566208. |
with the relatively recent introduction of the selective serotonin reuptake inhibitor (ssri) class of antidepressants, increased attention has been focused on the use of antidepressants in the treatment of mood disorders across the female life cycle. |
2004-01-28 |
2023-08-12 |
Not clear |