Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ruby P Huttner, Janet E Shepher. Gonadal steroids, selective serotonin reuptake inhibitors, and mood disorders in women. The Medical clinics of North America. vol 87. issue 5. 2003-12-04. PMID:14621331. |
gonadal steroids, selective serotonin reuptake inhibitors, and mood disorders in women. |
2003-12-04 |
2023-08-12 |
Not clear |
S Sundram, P R Joyce, M A Kenned. Schizophrenia and bipolar affective disorder: perspectives for the development of therapeutics. Current molecular medicine. vol 3. issue 5. 2003-11-26. PMID:12942993. |
polymorphisms of candidate genes have yielded potential leads such as dopamine beta hydroxylase in mood disorder and the serotonin transporter for treatment response. |
2003-11-26 |
2023-08-12 |
Not clear |
D N Mendhekar, D Gupta, V Girotr. Sertraline-induced hypomania: a genuine side-effect. Acta psychiatrica Scandinavica. vol 108. issue 1. 2003-11-21. PMID:12807380. |
antidepressants including selective serotonin reuptake inhibitor (ssri)-associated mania or hypomania has been well documented in the literature but these patients with switch have either mood disorders or various risk factors for bipolar disorder. |
2003-11-21 |
2023-08-12 |
Not clear |
Piotr M Czerski, Anna Leszczynska-Rodziewicz, Monika Dmitrzak-Weglarz, Pawel Kapelski, Sebastian Godlewski, Janusz Rybakowski, Joanna Hause. Association analysis of serotonin 2A receptor gene T102c polymorphism and schizophrenia. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 4. issue 2. 2003-09-16. PMID:12692777. |
the serotonin neurotransmitter has been associated with the pathogenesis of mood disorders and schizophrenia. |
2003-09-16 |
2023-08-12 |
Not clear |
Feng-Chang Yen, Chen-Jee Hong, Sheu-Jane Hou, Jiunn-Kae Wang, Shih-Jen Tsa. Association study of serotonin transporter gene VNTR polymorphism and mood disorders, onset age and suicide attempts in a Chinese sample. Neuropsychobiology. vol 48. issue 1. 2003-09-02. PMID:12886033. |
association study of serotonin transporter gene vntr polymorphism and mood disorders, onset age and suicide attempts in a chinese sample. |
2003-09-02 |
2023-08-12 |
human |
Feng-Chang Yen, Chen-Jee Hong, Sheu-Jane Hou, Jiunn-Kae Wang, Shih-Jen Tsa. Association study of serotonin transporter gene VNTR polymorphism and mood disorders, onset age and suicide attempts in a Chinese sample. Neuropsychobiology. vol 48. issue 1. 2003-09-02. PMID:12886033. |
the human serotonin transporter (5-htt) gene is an important candidate for the pathogenesis of mood disorders. |
2003-09-02 |
2023-08-12 |
human |
Feng-Chang Yen, Chen-Jee Hong, Sheu-Jane Hou, Jiunn-Kae Wang, Shih-Jen Tsa. Association study of serotonin transporter gene VNTR polymorphism and mood disorders, onset age and suicide attempts in a Chinese sample. Neuropsychobiology. vol 48. issue 1. 2003-09-02. PMID:12886033. |
associations have been reported between a variable-number tandem-repeat polymorphism in intron 2 of the serotonin transporter gene (5-httvntr) and mood disorders in a number of studies of western and chinese populations. |
2003-09-02 |
2023-08-12 |
human |
Su-Jane Wang, Chin-Feng Su, Yu-Heng Ku. Fluoxetine depresses glutamate exocytosis in the rat cerebrocortical nerve terminals (synaptosomes) via inhibition of P/Q-type Ca2+ channels. Synapse (New York, N.Y.). vol 48. issue 4. 2003-07-25. PMID:12687635. |
fluoxetine, an antidepressant that is used clinically in the treatment of mood disorders, is a selective serotonin reuptake inhibitor. |
2003-07-25 |
2023-08-12 |
rat |
C Faravelli, F Cosci, M Ciampelli, M A Scarpato, R Spiti, V Ricc. A self-controlled, naturalistic study of selective serotonin reuptake inhibitors versus tricyclic antidepressants. Psychotherapy and psychosomatics. vol 72. issue 2. 2003-06-11. PMID:12601227. |
to compare the effectiveness of serotonin reuptake inhibitors (ssris) and tricyclic antidepressants (tcas) for anxiety and mood disorders in a naturalistic setting. |
2003-06-11 |
2023-08-12 |
Not clear |
Akihiro Takano, Tetsuya Suhara, Yasuhiko Sudo, Makoto Inoue, Kenji Hashimoto, Ming-Rong Zhang, Tetsuya Ichimiya, Fumihiko Yasuno, Kazutoshi Suzuk. Comparative evaluation of two serotonin transporter ligands in the human brain: [(11)C](+)McN5652 and [(11)C]cyanoimipramine. European journal of nuclear medicine and molecular imaging. vol 29. issue 10. 2003-05-07. PMID:12271409. |
abnormalities of the 5-ht transporter have been suggested in mood disorders, since it is one of the major binding sites of antidepressants. |
2003-05-07 |
2023-08-12 |
human |
Luca Pania, Gian Luigi Gessa. Dopaminergic deficit and mood disorders. International clinical psychopharmacology. vol 17 Suppl 4. 2003-05-02. PMID:12685916. |
the roles of serotonin and noradrenaline in the pathogenesis of mood disorders have been elucidated by numerous studies, which support the therapeutic use of tricyclic antidepressants and selective serotonin re-uptake inhibitors. |
2003-05-02 |
2023-08-12 |
Not clear |
T Ohtsuki, H Ishiguro, S D Detera-Wadleigh, T Toyota, H Shimizu, K Yamada, K Yoshitsugu, E Hattori, T Yoshikawa, T Arinam. Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case-control samples and the NIMH Genetics Initiative Bipolar Pedigrees. Molecular psychiatry. vol 7. issue 9. 2003-04-30. PMID:12399948. |
we performed mutation and association analyses of the htr4 gene, on 5q32, encoding the serotonin 4 receptor in mood disorders and schizophrenia. |
2003-04-30 |
2023-08-12 |
Not clear |
T Ohtsuki, H Ishiguro, S D Detera-Wadleigh, T Toyota, H Shimizu, K Yamada, K Yoshitsugu, E Hattori, T Yoshikawa, T Arinam. Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case-control samples and the NIMH Genetics Initiative Bipolar Pedigrees. Molecular psychiatry. vol 7. issue 9. 2003-04-30. PMID:12399948. |
the polymorphisms associated with mood disorder were located within the region that encodes the divergent c-terminal tails of the 5-ht(4) receptor. |
2003-04-30 |
2023-08-12 |
Not clear |
Andrea C Nicholas, Lewis S Seide. Ambient temperature influences core body temperature response in rat lines bred for differences in sensitivity to 8-hydroxy-dipropylaminotetralin. The Journal of pharmacology and experimental therapeutics. vol 305. issue 1. 2003-04-22. PMID:12649391. |
agonist-induced decrease in core body temperature has commonly been used as a measure of serotonin1a (5-ht(1a)) receptor sensitivity in mood disorder. |
2003-04-22 |
2023-08-12 |
rat |
Ruby Klink, Malika Robichaud, Guy Debonne. Gender and gonadal status modulation of dorsal raphe nucleus serotonergic neurons. Part II. Regulatory mechanisms. Neuropharmacology. vol 43. issue 7. 2003-03-21. PMID:12504919. |
these results constitute strong evidence of mechanisms by which gender and hormonal fluctuations can modulate the 5-ht neurons function and influence vulnerability to mood disorders. |
2003-03-21 |
2023-08-12 |
rat |
J González-Maeso, R Rodríguez-Puertas, J J Meana, J A García-Sevilla, J Guimó. Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of alpha(2A)-adrenoceptors. Molecular psychiatry. vol 7. issue 7. 2003-02-25. PMID:12192620. |
abnormalities in the density of neuroreceptors that regulate norepinephrine and serotonin release have been repeatedly reported in brains of suicide victims with mood disorders. |
2003-02-25 |
2023-08-12 |
human |
M C Austin, R E Whitehead, C L Edgar, J E Janosky, D A Lewi. Localized decrease in serotonin transporter-immunoreactive axons in the prefrontal cortex of depressed subjects committing suicide. Neuroscience. vol 114. issue 3. 2002-12-20. PMID:12220580. |
however, the integrity of the serotonin innervation of the prefrontal cortex in mood disorders has not been directly investigated. |
2002-12-20 |
2023-08-12 |
human |
Alessandro Serretti, Silvano Cristina, Roberta Lilli, Cristina Cusin, Enrico Lattuada, Cristina Lorenzi, Barbara Corradi, Gaetano Grieco, Alfredo Costa, Filippo Santorelli, Francesco Barale, Giuseppe Nappi, Enrico Smerald. Family-based association study of 5-HTTLPR, TPH, MAO-A, and DRD4 polymorphisms in mood disorders. American journal of medical genetics. vol 114. issue 4. 2002-09-27. PMID:11992558. |
variants of the functional polymorphism in the serotonin transporter (upstream regulatory region: 5-httlpr), the tryptophan hydroxylase (tph), the monoamine oxidase a (mao-a), and the dopamine receptor d4 (drd4) genes have all been associated with mood disorders. |
2002-09-27 |
2023-08-12 |
human |
Savas Gurso. Absence of association of the serotonin transporter gene polymorphism with the mentally healthy subset of fibromyalgia patients. Clinical rheumatology. vol 21. issue 3. 2002-09-12. PMID:12111622. |
the serotonin transporter (5-htt) gene is considered to be a promising candidate for genetic involvement in some mood disorders owing to its role in the regulation of serotoninergic neurotransmission. |
2002-09-12 |
2023-08-12 |
human |
Tetsuya Ichimiya, Tetsuya Suhara, Yasuhiko Sudo, Yoshiro Okubo, Kazuhiko Nakayama, Masahiro Nankai, Makoto Inoue, Fumihiko Yasuno, Akihiro Takano, Jun Maeda, Haruo Shibuy. Serotonin transporter binding in patients with mood disorders: a PET study with [11C](+)McN5652. Biological psychiatry. vol 51. issue 9. 2002-08-21. PMID:11983185. |
serotonin transporter binding in patients with mood disorders: a pet study with [11c](+)mcn5652. |
2002-08-21 |
2023-08-12 |
Not clear |